osteoporosis Archives - Amazing Health Advances

Osteoporosis Warning: How Bone Loss Signals Inflammation and a Risk of Disease

The AHA! Team — Fri, 28 Feb 2025 06:11:34 +0000

Lori Alton via NaturalHealth365 – Osteoporosis, a disease in which bones become brittle and prone to breakage, is so widespread that 50 percent of all women over age 50 (and 25 percent of all over-50 men) will eventually suffer an osteoporosis-related bone fracture. A new study published in the Journal of Cachexia, Sarcopenia and Muscle reveals systemic inflammation and frailty as key contributors to osteoporosis and fracture risks. Unfortunately, the consequences of osteoporosis extend even beyond the pain and disabling effect of broken bones. In fact, recent research highlights a shocking connection between osteoporosis and life-threatening conditions such as heart disease, Alzheimer’s disease, and cancer. Fortunately, a combination of natural nutrients may help prevent osteoporosis – and offer protection against the devastating diseases that can accompany it. Pro-inflammatory molecules released by bone loss are linked to increased risk of deadly diseases The creation of bone is regulated by the actions of the body’s osteoblasts (bone cells that create new bone) and osteoclasts (cells that break down bone). At about age 35, the “balancing act” begins to shift – and the rate of bone breakdown starts to overtake the rate of bone development, leading to bone loss. Researchers are now learning that aging bones contain more “senescent” cells – meaning they have stopped reproducing themselves and now exclusively promote the breakdown of bone tissue. These senescent cells release pro-inflammatory molecules into the bloodstream, laying the groundwork for disease. Senescent bone cells have been found in plaque deposits in heavily calcified arteries. And, having large numbers of senescent cells in the bones is linked in studies with accelerated aging – particularly affecting the brain. Finally, people with osteoporosis have an increased risk of cancer. Keep in mind, when over-activated, the bone proteins that normally regulate bone maintenance and healing can lead to uncontrollable cell growth and replication. Discover a natural way to strengthen your bones The antioxidant vitamin C plays a critical role in preventing bone loss – which it does by preventing the oxidative stress that destroys bone structure. Vitamin C also plays a pivotal role in the formation and structure of bones by forming collagen and developing other bone proteins. If the body’s need for vitamin C is unmet, insufficient collagen production can result – leading to easily fractured bones. Many natural health experts believe osteoporosis is a vitamin C deficiency or “scurvy of the bones.” Bone-building vitamin C is found in citrus fruits, kiwi, strawberries, and bell peppers. However, supplementation may be necessary – especially if you have osteoporosis. By the way, for superior bioavailability (absorption), natural health experts advise using a liposomal form of vitamin C. Boron reduces the loss of indispensable calcium from the bones This little-known trace mineral packs a powerful punch when it comes to supporting bone health. Simply put, boron helps the body produce and use vitamin D – a mainstay of bone health. The mineral also helps regulate calcium, magnesium, and phosphorus levels – all “MVPs” of bone maintenance and support. A study published in the Federation of American Societies for Experimental Biology Journal showed that 3 mg of boron daily helped prevent calcium loss and bone demineralization in postmenopausal women. Natural health experts may advise 3 to 6 mg of boron daily. You can increase your dietary boron intake by eating organic nuts, beans, avocados, and whole grains. Calcium: The primary structural component of bones Bones contain 99 percent of the body’s calcium stores – integral to bone building. But, for your body to use calcium to build bone, you must have sufficient levels and adequate amounts of vitamin D. Deficiency in both minerals can cause bone loss and symptoms of muscle pain, muscle cramps, and weakness. Calcium exists in sardines, including the bones, dark leafy greens, and cruciferous vegetables, such as Brussels sprouts. Most adults require between 1,000 and 1,200 mg of calcium a day. Magnesium deficiency is a cause of “incalculable” suffering Magnesium works in concert with calcium to suppress hormones that break down bones – while activating enzymes needed to produce new bone. Unfortunately, experts estimate that about half of all Americans fail to consume enough of this important mineral. More than 40 percent of post-menopausal women have low magnesium blood levels, which can trigger excessive bone breakdown. In one landmark study on magnesium benefits, the researchers lamented that the deficiency of such an “inexpensive, low-toxicity nutrient” is currently causing diseases that are a source of untold “suffering and expense” worldwide. Eating organic dark leafy greens, potatoes, raisins, chocolate, pumpkin seeds, nuts, and avocados can help ramp up your dietary intake of magnesium. Of course, your holistic healthcare provider may recommend supplementing with magnesium to avoid shortfalls. Most natural healers recommend 250 to 750 mg a day. Magnesium citrate, magnesium glycinate, and magnesium taurate are considered the most bioavailable forms. Vitamin D helps improve calcium absorption Vitamin D reduces the activity of the pro-inflammatory signaling molecules that are released from senescent bone cells during bone breakdown. Unsurprisingly, vitamin D shortfalls are bad news for your bones and the rest of your body. Vitamin D deficiency has been identified as a major contributor to osteoporosis – as well as to cancer, heart disease, type 2 diabetes, and lowered cognitive functioning. This fat-soluble vitamin is found in cold-water fatty fish (like wild-caught salmon), as well as in mushrooms and egg yolks. Because the body manufactures vitamin D in response to sunlight, many natural health experts advise getting 20 minutes of direct sunlight three or four times a week. However, supplementation may be necessary to maintain healthy vitamin D levels, especially in northern climates. Just remember to opt for vitamin D3 (cholecalciferol) over vitamin D2. Vitamin K2 directs calcium in the body Vitamin K2’s job is to route calcium where it belongs – in the bones and teeth – while keeping it out of blood vessel walls (thereby helping to prevent heart disease). Vitamin K2 improves bone mineral density and is particularly beneficial for improving bone mineral content of the femoral bone – which is particularly susceptible to fracture during falls. Researchers have found that vitamin K2 is synergistic with vitamin D3 – meaning that each nutrient enhances the beneficial effect of the other. In an influential study published in Maturitas, supplementation with a combination of vitamins K2 and D3 protected and increased vertebral bone mass in postmenopausal women. Food sources of vitamin K2 include liver, egg yolks, and natto, a food made from fermented soybeans. Your doctor may recommend 100 mcg per day of vitamin K2 in the form of menaquinone-7, a highly available form of the nutrient. Prescription drugs can jeopardize zinc supply Zinc is needed for bone cells (osteoblasts) to create bone tissue – and is crucial for the entry of vitamin D into cells. And, yes, patients with osteoporosis have been found to have low levels of zinc. Ironically, pharmaceutical osteoporosis drugs – such as Boniva and Reclast – actually rob the body of this important trace mineral. The RDA for zinc is 8 mg for women and 11 for men. You can increase your dietary zinc intake by eating organic pumpkin seeds, chickpeas, nuts, yogurt, and cruciferous vegetables, such as broccoli. Grass-fed beef, oysters, and pasture raised poultry are also rich in zinc. As with the other vitamins and minerals, consult your holistic doctor before supplementing with zinc. With millions of people either suffering from osteoporosis – or at serious risk – it’s time to fight back. And, your best weapons in the battle to slow and reverse bone loss could be these non-toxic, natural micronutrients. Sources for this article include: NIH.gov LifeExtension.com SaveOurBones.com UniversityHealthNews To read the original article click here.

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How to Improve Your Bone, Skin and Hair Health Naturally

AHA Publisher — Wed, 30 Nov 2022 08:00:28 +0000

Lori Alton via NaturalHealth365 – Horsetail – a tall, shaggy weed that grows in wetlands and woodlands throughout North America – may not appear particularly valuable, attractive, or therapeutic. Yet this common plant, botanically known as Equisetum arvense, has been valued by natural healers since the days of the Greek and Roman empires – and for a good reason. Did you know that the leaves of horsetail feature an extremely high concentration of silica, a mineral necessary for the growth and maintenance of bones? And that’s not all. A recent scientific study has highlighted the impressive antibacterial, antioxidant and anti-inflammatory effects of this plant. Let’s see how these properties translate into 21st-century applications and health benefits. Great Way to Improve Your Bone and Joint Health Horsetail contains an array of minerals needed for bone health, including calcium, magnesium, potassium, manganese, phosphorus, and – most importantly – silica. Silica – a combination of silicon and oxygen – accounts for 25 percent of the plant’s weight. Natural health experts maintain that this mineral can help promote bone strength and facilitate the healing of fractures. Research has been encouraging. Animal studies have shown that horsetail improves the density of bones, making them less susceptible to fracture. In addition, recent cell studies suggest that horsetail may even help discourage osteoporosis. The researchers reported that horsetail inhibited bone cells called osteoclasts – which break down bone through resorption – while stimulating the activity of bone-building osteoblasts. By the way, anti-inflammatory compounds in horsetail – such as epicatechins and kynurenic acid – may help ease the pain, swelling, and stiffness of arthritic joints. Best-Kept Beauty Secret: Silica Promotes Thicker, Shinier Hair and Stronger Nails The benefits of horsetail fern aren’t just medicinal but also cosmetic. Natural beauty experts have long insisted that silica-rich horsetail can help repair brittle nails and restore dull, thinning locks. After all, silica plays a role in producing collagen – a vital component of healthy hair, skin, and nails – and research suggests that raising the level of silicon in hair fibers may help prevent hair loss while increasing brightness and sheen. The antioxidants in horsetail help reduce the damage caused by free radicals, thereby limiting the premature aging and “wear-and-tear” of hair fibers. In an influential three-month study published in The Journal of Clinical and Aesthetic Dermatology, women who complained of thinning hair were given a formulation high in horsetail-derived silica. The participants experienced increased hair growth and strength compared to the control group – with no adverse effects reported. Horsetail also benefits the fingernails by decreasing fragility, breakage, and unsightly ripples and grooves. Thicker, more lustrous hair and stronger, smoother fingernails – what’s not to love about that? Soothe Inflamed Gums and Boost Oral Health With Horsetail Research has shown that horsetail has potent activity against bacteria and fungi, including the Candida albicans fungus that causes oral thrush. It also has astringent effects, meaning that it can shrink inflamed tissues. As a result, natural healers advise using horsetail tea as an oral rinse to ease mouth sores and tender, irritated gums. For a soothing mouthwash, steep a teaspoon or two of dried horsetail in 8 ounces of boiling water for 5 to ten minutes. After being strained and cooled, the liquid can be used as a gargle. (If you prefer, you can simply brew horsetail tea using a pre-packaged commercial product). Incidentally, natural healers may also advise horsetail tea to treat fevers, bronchitis, flu, and conjunctivitis. With natural diuretic properties, horsetail is also believed to support bladder health and prevent kidney stones. Horsetail Can Provide “Head-to-Toe” Beauty Benefits In addition to using horsetail tea as a mouthwash, you can employ it topically as a soak to strengthen nails, as a facial toner to refresh skin, and as a volumizing hair rinse. You can also drink the tea, with experts advising up to two cups a day. However, consuming horsetail tea for more than seven days in a row is not recommended. It can cause health problems, including vitamin B1 deficiency if used long-term. Consult your knowledgeable integrative doctor before using horsetail tea or supplements. Here’s a fun fact: Horsetail is so sturdy that it was used in bygone days to scrub pans, pewter pots, and bottles. In fact, horsetail’s traditional names – pewterwort, bottle brush, and scouring rush – reflect this use. You may also see horsetail referred to as field horsetail, mare’s tail, candock, and shavegrass. Although you may see horsetail growing wild, leave the harvesting to qualified herbalists. A similar-looking variety of horsetail – Equisetum palustre, or marsh horsetail – is known to be poisonous. Fortunately, Equisetum arvense teabags and capsules are readily accessible online or at your favorite health food store. Horsetail, when used appropriately, is a remarkable herb that can enhance health, well-being, and appearance from the “inside out.” Sources for this article include: NIH.gov Healthyfocus.org Healthline.com NIH.com Therighttea.com To read the original article click here.

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Prunes Provide UNEXPECTED Health Benefits, New Study Suggests

AHA Publisher — Fri, 25 Feb 2022 08:31:12 +0000

Lori Alton via NaturalHealth365 – Osteoporosis, a thinning of the bones that increases susceptibility to fractures, can have devastating consequences. The National Institutes of Health reports that a shocking 50 percent of women over age 60 (along with 20 percent of men in that age group) will suffer a potentially debilitating osteoporosis-related fracture at some point. And, with the “graying” of America, rates of the disease (which disproportionately affects women) are rising. Experts predict that the national prevalence of osteoporosis among women aged 50 and older will reach 13.6 million by 2030. Given these grim statistics, a review of studies published this month in the journal Advances in Nutrition delivers particularly welcome news. The authors, a team of scientists at Penn State University, concluded that a natural dietary intervention – daily consumption of ordinary prunes- may help delay and even prevent the onset of osteoporosis. So let’s take a closer look at the review – and the bone-building benefits of prunes. Researchers: “Promising effects” on Bone Mineral Density Are One of the Many Benefits of Prunes Researchers analyzed data from 28 studies – 16 involving animals and 12 involving humans to conduct the review. They identified multiple studies that showed that eating 100 grams of prunes (about three ounces, or ten prunes) every day for a year increased the mineral density of bones in the forearms and lower spines of postmenopausal women. And eating between 50 and 100 grams of prunes a day for six months was also shown to decrease a marker of resorption (bone loss) known as TRAP-5b. Dr. Connie Rogers, an associate professor of nutritional sciences and physiology at Penn State, noted that the prunes helped to inhibit inflammation and suppress markers of oxidative stress. (Oxidative stress and inflammation, triggered by the loss of estrogen in postmenopausal women, are believed to lie at the root of osteoporosis). The researchers concluded that incorporating prunes into the diet could help strengthen bones. Benefits of Prunes Include Reducing Bone Loss by Multiple Mechanisms It turns out that the benefits of prunes for bone health are multi-faceted. For one thing, prunes contain antioxidants, such as anthocyanins, that help battle oxidative stress. (In fact, scientists have found that plums – which are basically prunes before they have been dried – contain roughly twice as many antioxidants as peaches and nectarines. And the drying process causes no loss of antioxidants). Prunes also contribute bone-building minerals, along with hefty amounts of vitamin K. Vitamin K, once known primarily for its importance to normal blood clotting, has created a “buzz” in recent research with its ability to escort calcium from the blood and into the bones, where it belongs. The Penn State team also reported that prunes caused a change in the gut microbiome (the community of bacteria in the intestinal tract), which helped lower pro-inflammatory cytokine levels in the colon. Finally, prunes decreased levels of malondialdehyde – a marker of oxidative stress – while increasing the expression of important antioxidants such as glutathione and superoxide dismutase. Additional Studies Strongly Support Benefits of This Dried Fruit for Bone Health In older – but still-reputable – research published in 2009 in Aging Research Review, researchers credited prunes with being the “most effective” fruit in both preventing and reversing bone loss. The scientists used micro-computed tomography to show that prunes could restore bone mineral density to normal levels in rats with osteoporosis, reversing bone loss about as effectively as hormone therapy In a three-month clinical trial opostmenopausalal women conducted by the same research team, prunes significantly increased markers of bone formation, such as bone-specific alkaline phosphatase. Prunes Are a Nutritional Jackpot of Phytonutrients, Vitamins, Minerals, and Fiber Prunes, botanically known as Prunus domestica, are a rich source of high-quality nutrients. A one-ounce serving contains a fifth of the adult recommended dietary intake for vitamin K, along with various B vitamins, which are needed to convert food to energy and a healthy nervous sys em. And prunes offer an array of bone-building minerals – including magnesium, potassium, and phosp orus. The serving also contains 2 grams of heart-healthy dietary fiber. Yet the caloric cost is a reasonable 67 calories (meaning that even a three-ounce serving, like the one used in studies, clocks in at about 200 calories – less than that of a typical can y bar). And, despite their sumptuous, candy-sweet taste, they not only don’t raise blood sugar but may help regulate levels. (Researchers chalk this up to prunes’ content of dietary fiber and adiponectin, a blood sugar-regulating hormone). Portable, convenient and tasty, prunes are easy to incorporate into the diet. However, to avoid diarrhea, some natural health experts advise keeping their consumption to half a cup a day and limiting prune juice to no more than 8 ounces a day. While many people are familiar with their stimulating effects on the digestive tract – and their use as a trusted dietary intervention for constipation – it’s likely that far fewer realize just how much these nutritious dried fruits can bolster and protect the strength and density of bones. As the new review suggests, eating prunes may help you “stand strong” against a crippling disease. Sources for this article include: ScienceDaily.com NIH.gov Healthline.com NIH.gov NIH.gov NIH.gov To read the original article click here.

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Men With High Levels of Body Fat May Be at Risk for Osteoporosis

AHA Publisher — Tue, 15 Feb 2022 08:00:17 +0000

Endocrine Society via Newswise – Men with high levels of body fat have lower bone density and may be more likely to break a bone than those with normal levels of body fat, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Most studies have shown positive or neutral effects of body fat mass—the weight of fat in your body—on bone health. Lean mass is the entire weight of your body, including organs, skin and bones, minus fat. Health care providers often assume people with higher body weight have high bone density and are at low risk of fracture, and these patients are less likely to be screened for osteoporosis. “We found that higher fat mass was related to lower bone density, and these trends were stronger in men than women,” said Rajesh K. Jain, M.D., of University of Chicago Medicine in Chicago, Ill. “Our research suggests that the effect of body weight depends on a person’s makeup of lean and fat mass, and that high body weight alone is not a guarantee against osteoporosis.” The researchers analyzed the bone mineral density and body composition data of 10,814 people under 60 years old from the National Health and Nutrition Examination Survey (NHANES) 2011-2018. They found a strong positive association between lean mass and bone mineral density in both men and women. Conversely, fat mass had a moderately negative association with bone mineral density, especially in men. “Health care providers should consider osteoporosis screening for patients with high body weight, especially if they have other risk factors like older age, previous fracture, family history, or steroid use,” Jain said. To read the original article click here.

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AMAZING Compound Found in Tomatoes Can Strengthen Bones and Help Prevent Osteoporosis

AHA Publisher — Mon, 27 Dec 2021 08:00:25 +0000

Lori Alton via NaturalHealth365 – Osteoporosis, characterized by low bone mineral density, causes brittle bones susceptible to breakage. Odds of developing osteoporosis skyrocket with advancing age – with women disproportionately affected. About 30 percent of postmenopausal women in the United States are affected by osteoporosis, and – according to the International Osteoporosis Foundation – roughly one in three women over age 50 will experience a bone fracture due to the condition. (For men over 50, the odds of an osteoporosis-related fracture are one out of five). Unfortunately, pharmaceutical therapies for osteoporosis can feature horrific side effects, including jaw osteonecrosis, thromboembolisms, increased cancer risk, and – ironically – bone fractures. This has led to an urgent search for effective natural interventions. And, there’s good news on that front. New research suggests that lycopene, the antioxidant plant pigment responsible for the ruby-red coloration of tomatoes, may help to stop the progression of osteoporosis in its tracks. New Study Explores Exciting Potential of Tomato Compound to Support Bone Health In a study conducted at Azienda University Hospital in Catanzaro, Italy, and published in the Journal of Translational Medicine, scientists set out to investigate the effects of lycopene on bone mineral density. Some of the research centered around test-tube studies – and was designed to evaluate the effects of lycopene on bone cells such as osteoblasts (the specialized cells that synthesize bone matrix). But, it wasn’t all lab tests. The team also conducted a clinical trial involving 39 postmenopausal women. In this deceptively small trial, participants received 150 ml a day of a lycopene-rich sauce made from vine-ripened tomatoes. The control group – 39 women of comparable age and health status – received no tomato sauce. Lycopene Plays a Vital Role in the Regulation of Bone Metabolism and IMPROVES Bone Density The study results were encouraging. The team found that lycopene helps activate cellular systems – such as the WNT/beta-catenin pathway – that help prevent bone loss. In addition, lycopene appears to improve bone resistance and repair by influencing collagen biosynthesis. But, it was the clinical study that yielded the most dramatic results. To put it simply, at the end of the three-month study, the control group had a loss of bone density – but the lycopene group did not. Lycopene also reduced biomarkers of bone loss (and the team noted that it did this about as well as raloxifene, a pharmaceutical anti-osteoporosis medication). The impressed researchers concluded that lycopene improves bone mineral density and can help prevent the bone loss that results from osteoporosis – potentially exciting news for the 10 million people in the United States suffering from the disease. Additional Research Backs Therapeutic Effects of Lycopene Lycopene is a powerful antioxidant that can scavenge harmful free radicals that otherwise cause oxidative stress and damage. Researchers have learned that oxidative stress can increase osteoclast cells, which degrade bone and cause bone loss (a process also known as resorption). So, it’s not surprising that additional research helps to confirm the therapeutic potential of lycopene. In a separate study published in Osteoporosis International, the team found that 30 mg of lycopene a day – the amount found in two glasses of tomato juice – could decrease bone resorption and prevent bones from becoming brittle and prone to breakage. And a 2020 review of studies published in the International Journal of Molecular Science (IJMS) concluded that there is a positive correlation between lycopene consumption and prevention of bone loss. Boost Dietary Intake of Lycopene With Ripe, Red Tomatoes According to the review published in IJMS, most people get about 80 percent of their lycopene by way of tomatoes – making them an important part of a healthy, bone-supporting diet. In addition to consuming stewed tomatoes and tomato sauce, you can get lycopene from fresh tomatoes and tomato juice. Lycopene is fat-soluble, so it is best absorbed with some healthy fat. This is one reason why natural health experts and nutritionists are so enthusiastic about serving tomatoes alongside avocados or olives. (For the “best of all possible worlds,” add tomatoes and olives to your favorite guacamole recipe). If you absolutely can’t tolerate tomatoes in any form, other sources of lycopene include watermelon, guava, papayas, pink or red grapefruit, red cabbage, persimmons, and, somewhat surprisingly, asparagus. Many researchers believe that tomatoes release more lycopene when cooked, although not all scientists agree. By the way, it’s not only women who benefit from this amazing compound. Men can – and do – suffer from osteoporosis. In addition, lycopene is important for prostate health. Whether you eat tomatoes raw or cooked, one thing is clear. These savory fruits (yes, tomatoes are technically fruit) can be a valuable natural ally in the fight against osteoporosis. Sources for this article include: HealthyDirections.com InternationalOsteoporosisFoundation.com NIH.gov Healthline.com To read the original article click here.

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Top Nutrients to Slash Your Risk of Bone Fracture

AHA Publisher — Wed, 25 Aug 2021 07:00:11 +0000

Stephanie Woods via NaturalHealth365 – Bone loss is widely considered to be just another part of the aging process. In fact, many conventionally-trained physicians believe that it is perfectly “understandable” for a person to experience a higher risk of osteoporosis later in life. In addition, Western medicine is quite accepting of the fractures that result from these conditions. In fact, researchers estimate that 50% of U.S. women and 20% of men will have an osteoporotic fracture after 49 years of age. But, make no mistake about it, bone fractures due to osteoporosis can be avoided. FACT: Bone Loss is NOT a Natural Part of the Aging Process; Vital Nutrients Can Help You Maintain Strong Bones The truth is osteoporosis is not a normal part of aging. Having said that, bone loss can occur due to age, but that is typically due to vitamin and nutrient deficiencies. Just keep in mind, by getting all of the vital nutrients you need each day, you can have healthy, strong bones as you age, even well into your “golden years.” For the basic facts, let’s start here: Many of the “bone-building nutrients” needed can be obtained by eating a well-rounded, organic diet loaded with organic dark (mineral rich) leaky vegetables and some fruit. The key here is to get your food from the best sources possible. And, yes, local farmers markets can be a great place to start. Of course, depending on your own health status – in many cases – nutritional supplements may be needed to correct any deficiencies that exist. THESE Critical Nutrients Can Help You Build Strong Bones and Prevent Bone Fractures, Studies Suggest Vitamin D3 and calcium As children, it is drilled into us, “drink your milk so you can have strong bones!” But, for the most part, we have to thank the milk industry for that marketing hype. The truth is: there are no “magic bullets” when it comes to keeping bones healthy and strong. It really comes down to a combination of nutrients like vitamin D3 – mainly generated from adequate sun exposure – and calcium from dark leafy greens like dandelion greens. In addition, there are several vitamins and minerals that the body needs in order to form strong bones. If you are concerned about your bone health, talk to an integrative physician or health coach (with experience in nutrition) about nutrients like boron, magnesium and zinc … that improve the absorption of vitamin D3. In terms of healthy food choices for vitamin D and calcium, raw milk, organic broccoli, kale, collard greens, sesame seeds, pasture-raised eggs, wild mushrooms and grass-fed beef liver can help. Don’t forget your vitamin K A study published in 2019 found that a deficiency in vitamin K and other nutrient deficiencies can lead to increased fracture rates. This is because vitamin K plays a significant role in strengthening bones (known as mineralization) and bone formation. There are two types of vitamin K, called K1 and K2. While deficiencies in both vitamins do seem to negatively affect bone loss, vitamin K2 is believed to be more integral to bone protection and strengthening. Good sources of vitamin K include, organic spinach, Brussels sprouts, wild-caught fish, cabbage, turnip greens, grass-fed liver. Are you getting enough vitamin B12 Many people are deficient in this essential vitamin and don’t even know it! A Tufts University study found a link between low vitamin B12 and osteoporosis in both women and men. B12 is a water-soluble vitamin that is absorbed in the lining of the stomach. As people age, especially as they reach their 80s, they can experience changes in the stomach lining that inhibits their body’s ability to absorb the nutrient efficiently or effectively. Simply put, there is plenty of evidence to suggest that B12 is important to bone health and that a deficiency can increase the risk of fractures and osteoporosis. Some of the best sources for B12 are: wild-caught trout, salmon, spirulina and, of course (if necessary), a high quality, B12 supplement. The value of vitamin C Vitamin C is tissue building and strengthens immunity, but it is also a key component of collagen formation in the body which is the foundation of bone mineralization. Several studies have found a link between greater bone density and higher levels of vitamin C in the body. Again, as a water-soluble vitamin, it gets absorbed in the intestines. Unfortunately, too many people are vitamin C deficient – which only increases the risk of health issues. For a good food source of vitamin C, try eating more organic bell pepper, blueberries, strawberries, cauliflower, broccoli, lemons, oranges and kale. Plus, as a general rule, a good quality vitamin C supplement can’t hurt, as well. Just check with your integrative physician before making any changes to your diet. Magnesium deserves our attention Magnesium benefits the body in many ways, from regulating blood pressure and blood sugar levels to making protein and increasing bone mineral density. It works very closely with calcium to improve bone health and strengthen bones. When taking magnesium, look for chelated forms of magnesium that are easier for the body to absorb. The body does not absorb magnesium oxide as easily as it does chelated forms of the mineral. It is also a good idea to divide magnesium, taking them two or three times during the day. Food sources include, organic nuts, brown rice, seeds, whole grains, legumes and dark leafy green vegetables. Boron – in small amounts – can be powerful Boron is another important nutrient when it comes to bone formation and growth. It is believed to increase bone building and decrease bone loss by aiding the body in more efficient calcium utilization. In fact, studies have shown that a deficiency in boron leads to decreased bone strength. Science is still exploring the link between bone strength and boron, but it is believed that increasing your boron intake can help improve your bone health. Food sources include, organic apples, nuts, avocados, broccoli, legumes, tomatoes, bananas and prune juice. Bottom line: Focusing on better bone health now can help prevent falls and fractures later. It doesn’t matter if you are 18 or 80; making adjustments to your diet and taking the right bone-building supplements will positively affect your body. And, remember, it’s never too late to build stronger bones. Sources for this article include: LifeExtension.com AmericanBoneHealth.org AmericanBoneHealth.org JamaNetwork.com ResearchGate.net TuftsJournal.Tufts.edu NIH.gov Academic.OUP.com NIH.gov To read the original article click here.

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Excess Caffeine Intake May Be Linked to Increased Risk of Osteoporosis

AHA Publisher — Mon, 26 Jul 2021 07:00:37 +0000

University of South Australia via News-Medical – University of South Australia researchers have a bone to pick when it comes to drinking too much coffee as new research finds that excess caffeine may be linked to an increased risk of osteoporosis. Investigating the effects of coffee on how the kidneys regulate calcium in the body, researchers found that high doses of caffeine (800 mg) consumed over a six-hour period almost doubled the amount of calcium lost in the urine. This is the first study to report the impact of high-dose, short-term caffeine intake on renal clearance of calcium, sodium, and creatinine in healthy adults. UniSA’s Dr Hayley Schultz says with the emergence of an increasing ‘coffee culture’ it’s important for people to understand the impacts of what they are putting into their bodies. “Caffeine is one of the most widely used recreational drugs in the world, with 80 per cent of adults consuming at least one caffeinated beverage per day. It’s a common stimulant, consumed by professionals, parents, shift workers, and teenagers alike to start their day and stay alert – even the military use caffeine to help combat sleepiness. But while coffee has its perks, it’s also important to acknowledge its fallbacks – one of them being how our kidneys handle calcium. Our research found that people who consume 800 mg of caffeine over a typical working day will have a 77 per cent increase in calcium in their urine, creating a potential deficiency that could impact their bones.” Dr Hayley Schultz, UniSA Osteoporosis is a chronic, painful, and debilitating disease which makes your bones less dense and more susceptible to fracture. More common in women, it occurs when bones lose calcium and other minerals faster than the body can replace them. In Australia, an estimated 924,000 people have osteoporosis. The double-blind clinical study saw participants chew caffeine or a placebo gum for five minutes at two-hour intervals over a six-hour treatment period (total caffeine 800 mg). While the primary research objective was to examine the impact of caffeine consumption on wakefulness and other factors, this sub-study aimed to evaluate the impact of caffeine consumption on the renal clearance of calcium. Co-researcher, UniSA’s Dr Stephanie Reuter Lange says understanding the long-term impacts of high caffeine consumption is especially important for higher risk groups. “The average daily intake of caffeine is about 200 mg – roughly two cups of coffee. While drinking eight cups of coffee may seem a lot (800 mg of caffeine), there are groups who would fall into this category,” Dr Reuter Lange says. “People at risk could include teenagers who binge-consume energy drinks are at are at risk because their bones are still developing; professional athletes who use caffeine for performance enhancement; as well as post-menopausal women who often have low blood calcium levels due to hormonal changes and lack sufficient daily dietary calcium intake. “Increasingly, we are also seeing high levels of caffeine among shiftworkers who need to stay alert over the night-time hours, as well as those in the military who use caffeine to combat sleep deprivation in operational settings. “Caffeine in moderation certainly has its pros. But understanding how excess consumption could increase the risks of a highly preventable disease such as osteoporosis, is important.” From here, researchers will explore and predict the impact of different levels of caffeine intake on short- and long-term bone health, with the aim to inform dietary guidelines in Australia. To read the original article click here.

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Heat and Gut Microbiota Promote Stronger Bones

AHA Publisher — Tue, 15 Sep 2020 07:00:01 +0000

University of Geneva via News-Medical Net – Osteoporosis, a bone disease linked to ageing, is characterized by a loss of bone density, micro-architectural deterioration of the bones and an increased risk of fractures. With one third of postmenopausal women affected, it is a major public health problem. Through epidemiological analyses, laboratory experiments and state-of-the-art metagenomic and metabolomics tools, a research team from the University of Geneva (UNIGE), in Switzerland, has observed that exposure to warmer ambient temperatures (34 °C) increases bone strength, while preventing the loss of bone density typical of osteoporosis. Moreover, this phenomenon, linked to a change in the composition of gut microbiota triggered by heat, could be replicated by transplanting the microbiota of mice living in a warm environment to mice suffering from osteoporosis. Indeed, after the transplant, their bones were stronger and denser. These results, to be discovered in Cell Metabolism, make it possible to imagine effective and innovative interventions for prevention and treatment of osteoporosis. Many biologists are familiar with Allen’s Rule, from 19th-century naturalist Joel Asaph Allen, according to which animals living in warm areas have a larger surface area in relation to their volume than animals living in colder environment. Indeed, a larger skin surface allows better evacuation of body heat. “In one experiment, we placed newborn mice at a temperature of 34 °C in order to minimise the heat shock associated with their birth. We found that they had longer and stronger bones, confirming that bone growth is affected by ambient temperature,” explains Mirko Trajkovski, Professor at the Department of Cell Physiology and Metabolism and at the Diabetes Centre of the UNIGE Faculty of Medicine, who led the study. But what about adulthood? Consistent Epidemiological Data By placing several groups of adult mice in a warm environment, the scientists observed that while bone size remained unchanged, bone strength and density were largely improved. They then repeated their experiment with mice after an ovariectomy modelling post-menauposal osteoporosis. “The effect was very interesting. The simple fact of warming the living environment of our mice protected them from the bone loss typical of osteoporosis!” (Claire Chevalier, Study First Author and Researcher in Professor Trajkovski’s Laboratory) What about human beings? The research team analysed global epidemiological data on the incidence of osteoporosis in relation to the average temperature, latitude, calcium consumption and vitamin D levels. Interestingly, they found that the higher the temperature, the fewer hip fractures –one of the main consequences of osteoporosis– regardless of other factors. “We found a clear correlation between geographical latitude and hip fractures, meaning that in the northern countries the incidence is higher compared to the warmer south”, says Mirko Trajkovski. “Normalising the analysis of the known players such as vitamin D or calcium did not modify this correlation. However, when we excluded the temperature as the determinant, the correlation was lost. This is not to say that calcium or vitamin D do not play a role, either alone or in combination. However, the determining factor is heat -or lack thereof.” How the Microbiota Adapts Specialists in the microbiota, the Geneva scientists wanted to understand its role in these metabolic modifications. To this end, they transplanted the microbiota of mice living in a 34° environment to osteoporotic mice, whose bone quality was rapidly improved. “These findings may imply an extension to Allen’s rule, suggesting elongation-independent effects of the warmth, which predominantly favours bone density and strength during adulthood through microbiota alterations”, says Mirko Trajkovski. Thanks to the state-of-the-art metagenomic tools developed in their laboratory, the scientists then succeeded in understanding the role played by microbiota. When adapts to heat, it leads to a disruption in the synthesis and degradation of polyamines, molecules that are involved in ageing, and in particular in bone health. “With heat, the synthesis of polyamines increases, while their degradation is reduced. They thus affect the activity of osteoblasts (the cells that build bones) and reduce the number of osteoclasts (the cells that degrade bones). With age and menopause, the exquisite balance between the osteoclast and osteoblast activity is disrupted,” explains Claire Chevalier. “However, heat, by acting on the polyamines, which we found to be partly regulated by the microbiota, can maintain the balance between these two cell groups.” These data therefore indicate that exposure to warmth could be a prevention strategy against osteoporosis. Developing New Treatments The influence of microbiota on metabolism is being better understood. However, in order to be able to use this knowledge to develop therapeutic strategies, scientists must identify precisely the role of particular bacteria in particular diseases. In the context of their work on osteoporosis, Professor Trajkovski’s team has been able to identify certain important bacteria. “We still need to refine our analyses, but our relatively short-term goal would be to identify candidate bacteria, and develop several ‘bacterial cocktails’ to treat metabolic and bone disorders, such as osteoporosis, but also to improve insulin sensitivity, for example,” the authors conclude. To read the original article click here.

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The Effect of Antibiotics on Bone Mass

AHA Publisher — Fri, 20 Mar 2020 07:00:24 +0000

Chloe Bennett, B.Sc. via News-Medical Net – Novel research has found a link between the antibacterial and antifungal agent triclosan and an increased prevalence of osteoporosis in American females. Researchers from the Hangzhou Medical College School of Public Health, China, found that women with higher urinary levels of triclosan were more likely to have lower bone mineral density. Previous research has found triclosan to adversely affect the bone density of animals and cell lines. However, very little was known about the effect exposure has on human bone health. What is Triclosan? Triclosan is an antibacterial and antifungal agent commonly found in mouthwash, soaps, toothpaste and hand sanitizers. As an endocrine-disrupting chemical, many have been skeptical about its safety, namely, the United States Food and Drug Administration, who banned its use in soap and over-the-counter antiseptic products in 2017 following a lack of evidence that triclosan was safe. Triclosan and Bone Health The researchers examined the data from 1,848 women and analyzed the association between bone mineral density and the concentration of triclosan in their urine. The women were divided into three groups based on their triclosan levels. Those in group 3, with the highest concentrations of triclosan, were found to have the lowest bone mineral density in their femur, lumbar spine, and intertrochanter, compared to women in group 1, with the lowest levels of urinary triclosan. Furthermore, when compared to those in group 1, women in group 3 were 2.5 times more likely to be diagnosed with osteoporosis of the intertrochanter. These relationships: the inverse relationship between bone mineral density and urinary triclosan levels; and the positive relationship between triclosan and osteoporosis was found to be stronger in postmenopausal women. Despite the associations shown, the findings cannot be interpreted as showing that exposure to triclosan causes the onset of osteoporosis. A range of other factors or chemical exposure were not controlled for in the study, and therefore, may have affected the results seen. Some argue that it might be likely that triclosan alters the biochemistry of bones. However, it might be too far to claim that such exposure causes osteoporosis. Furthermore, Professor Hammock from the University of California states that the benefits of triclosan need to be carefully examined to justify its use if there are potential adverse effects. Additionally, research has found the prescription of some antibiotics to not negatively impact bone health. Type 1 diabetics are associated with a reduction in bone mineral density and increased risk of fracture. There is evidence to suggest that the prescription of tetracycline derivatives and their beneficial anti-inflammatory and anti-collagenolytic properties may be useful in preventing further deterioration in bone strength. The research used a mice model to investigate the impact of prescribing doxycycline an antibiotic of tetracycline-class on bone density. They concluded that the long-term use of the antibiotic did not improve the bone disease. However, it was not deleterious to the biomechanical or microarchitecture of healthy bones in diabetic mice. Other Adverse Effects of Antibiotic Use Research has investigated the impact of repeated antibiotic use. The mice study analyzed the impact of the consumption of three short causes of amoxicillin and tylosin – a class of antibiotics commonly prescribed in children. The mice were either given one of the antibiotics, a mixture of both and, as part of the control group were given none. The amount and number of prescriptions given matched the average amount a child is typically given during the first year of infancy. The study found that short, high doses of amoxicillin negatively affected bone growth potentially stunting growth while tylosin was associated with long-lasting effects on weight. These findings align with research suggesting that prescribing antibiotics during crucial developmental periods can alter the gut’s bacterial composition and metabolism which can increase the risk of obesity. Despite the current study being limited to mice, the results align with several other studies that have demonstrated the adverse effects on children of prescribing antibiotics early in life. This article has been modified. To read the original article click here.

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