increased blood sugar Archives - Amazing Health Advances https://amazinghealthadvances.net/tag/increased-blood-sugar/ Your hub for fresh-picked health and wellness info Tue, 02 Nov 2021 04:46:04 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.1 https://amazinghealthadvances.net/wp-content/uploads/2019/08/AHA_Gradient_Bowl-150x150.jpg increased blood sugar Archives - Amazing Health Advances https://amazinghealthadvances.net/tag/increased-blood-sugar/ 32 32 Tissue Engineering Could Provide Diabetes Cure https://amazinghealthadvances.net/tissue-engineering-could-provide-diabetes-cure-7654/#utm_source=rss&utm_medium=rss&utm_campaign=tissue-engineering-could-provide-diabetes-cure-7654 https://amazinghealthadvances.net/tissue-engineering-could-provide-diabetes-cure-7654/#respond Tue, 02 Nov 2021 07:00:03 +0000 https://amazinghealthadvances.net/?p=13218 Abigail Klein Leichman via Israel21c – A novel approach to treating type 2 diabetes under development at the Technion-Israel Institute of Technology uses tissue engineering to create muscle cells that absorb sugar at increased rates. Diabetic mice treated in this manner displayed normal blood sugar levels for months after a single autograft procedure using their own enhanced muscle cells. The tissue-engineering treatment is part of a research study led by Prof. Shulamit Levenberg and PhD Student Rita Beckerman from the Technion’s Stem Cell and Tissue Engineering Laboratory. “By taking cells from the patient and treating them, we eliminate the risk of rejection,” Levenberg explained. Type 2 diabetes is caused by insulin resistance and cells’ reduced inability to absorb sugar, leading to increased blood-sugar levels. Its long-term complications include heart disease, strokes, retina damage, kidney failure and poor blood flow in the limbs. Although this chronic and common disease can be treated by a combination of lifestyle changes, medication and insulin injections, ultimately it is associated with a 10-year reduction in life expectancy. Currently around 34 million Americans suffer from diabetes, mostly type 2. An effective treatment could significantly improve both quality of life and life expectancy. The same method could also be used to treat various enzyme deficiency disorders. Researchers observed that the engineered muscle cells not only absorbed sugar correctly, improving blood-sugar levels, but also induced improved absorption in the mice’s other muscle cells. ‘ After the procedure, the mice remained diabetes-free for four months – the entire period they remained under observation. Their blood-sugar levels remained lower, and they had reduced levels of fatty liver normally seen in type 2 diabetes. Findings from the study, funded by Rina and Avner Schneur as part of the Rina and Avner Schneur Center for Diabetes Research, were recently published in Science Advances. Other scientists participating in the study are from Ben-Gurion University of the Negev; The Hospital for Sick Children, Toronto; and Ichan School of Medicine at Mount Sinai, New York City. To read the original article click here.

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]]> https://amazinghealthadvances.net/tissue-engineering-could-provide-diabetes-cure-7654/feed/ 0 A Cure for Diabetes? https://amazinghealthadvances.net/a-cure-for-diabetes-7634/#utm_source=rss&utm_medium=rss&utm_campaign=a-cure-for-diabetes-7634 https://amazinghealthadvances.net/a-cure-for-diabetes-7634/#respond Mon, 25 Oct 2021 07:00:03 +0000 https://amazinghealthadvances.net/?p=13141 American Technion Society via Newswise – A novel approach to treating type 2 diabetes is being developed at the Technion. The disease, caused by insulin resistance and reduction of cells’ ability to absorb sugar, is characterised by increased blood sugar levels. Its long-term complications include heart disease, strokes, damage to the retina that can result in blindness, kidney failure, and poor blood flow in the limbs that may lead to amputations. It is currently treated by a combination of lifestyle changes, medication, and insulin injections, but ultimately is associated with a 10-year reduction in life expectancy. Led by Professor Shulamit Levenberg, Ph.D. student Rita Beckerman from the Stem Cell and Tissue Engineering Laboratory in the Technion’s Faculty of Biomedical Engineering presents a novel treatment approach, using an autograft of muscle cells engineered to take in sugar at increased rates. Mice treated in this manner displayed normal blood sugar levels for months after a single procedure. The group’s findings were recently published in Science Advances. Muscle cells are among the main targets of insulin, and they are supposed to absorb sugar from the blood. In their study, Prof. Levenberg’s group isolated muscle cells from mice and engineered these cells to present more insulin-activated sugar transporters (GLUT4). These cells were then grown to form an engineered muscle tissue, and finally transported back into the abdomen of diabetic mice. The engineered cells not only proceeded to absorb sugar correctly, improving blood sugar levels, but also induced improved absorption in the mice’s other muscle cells, by means of signals sent between them. After this one treatment, the mice remained cured of diabetes for four months – the entire period they remained under observation. Their blood sugar levels remained lower, and they had reduced levels of fatty liver normally displayed in type 2 diabetes. “By taking cells from the patient and treating them, we eliminate the risk of rejection,” Prof. Levenberg explained. These cells can easily integrate back into being part of the body and respond to the body’s signalling activity. Currently around 34 million Americans, just over 1 in 10, suffer from diabetes, 90% of them from type 2 diabetes. An effective treatment – and one that is a one-time treatment rather than daily medication – could significantly improve both quality of life and life expectancy of those who have diabetes. The same method could also be used to treat various enzyme deficiency disorders. To read the original article click here.

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