When to See a Doctor for Swelling in the Arms or Legs

The AHA! Team — Mon, 17 Feb 2025 06:27:50 +0000

Morgan deBlecourt via Duke Health – While minor swelling is common and not usually a cause for concern, swelling that is excessive, unexplained, or long-lasting may be a sign of a medical problem. Knowing when to seek care is important, since some causes of swelling can be medical emergencies. Here, Duke vascular expert Dan Geersen, PA-C, MPAP, talks about the different types of swelling and explains which symptoms are red flags. Causes of Swelling in the Arms and Legs According to Geersen, swelling can be caused by a range of conditions, from bug bites to bruises. After an injury, your body sends fluid to the affected area to help it heal. As the injury heals, excess fluid drains away and the swelling goes down. In some cases, however, your body may not be able to adequately circulate fluid, especially in areas that are farthest from your heart, like your arms, hands, legs, and feet. This type of swelling is called peripheral edema, and it can signal more dangerous issues, including: Blood clots that can travel to your heart, lungs, or brain Heart disease and heart failure Infection Kidney damage or disease Liver disease Lymphedema Severe allergic reactions Venous disease When to Seek Care for Swelling You should seek emergency care if you have sudden, unexplained swelling in just one limb or if it occurs along with chest pain, trouble breathing, coughing up blood, fever, or skin that is red and warm to the touch. These can be symptoms of dangerous conditions like deep vein thrombosis (a blood clot in the leg), pulmonary embolism (a blood clot in the lungs), or cellulitis (a skin infection). If you experience swelling that does not go away on its own, make an appointment to see your primary doctor. If the issue doesn’t improve, ask your doctor for a referral to a vascular specialist. Duke offers a special Limb Swelling Clinic for just these kinds of issues. “If you have any kind of unexplained swelling, we want you to come in,” Geersen said. “We’ll do the proper work-up to make sure you get the help you need.” To read the original article click here.

The post When to See a Doctor for Swelling in the Arms or Legs appeared first on Amazing Health Advances.

Australian Scientists Develop a Nasal Spray That Could Stop SARS-CoV-2 Infection

AHA Publisher — Thu, 01 Oct 2020 07:00:21 +0000

Angela Betsaida B. Laguipo, BSN via News-Medical Net – As the coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to wreak havoc globally, scientists race to develop an effective medicine or vaccine to fight the infection. With more than 33.5 million people infected since the pandemic started in December 2019, finding a treatment for those infected is crucial to stemming its spread. Now, a biotech company in Australia, Ena Respiratory, said that a nasal spray it is developing might help boost the human immune system to fight flu and common colds, significantly reduced the growth of the coronavirus in a recent study in animals. The potential nasal spray may not only help treat COVID-19 but also prevent it. The Nasal Spray The novel product, called INNA-051, is being developed by Ena Respiratory, and laboratory experiments have shown that it reduced viral replication by as much as 96 percent in the animal study. Spearheaded by Public Health England’s (PHE) Deputy Director, Professor Miles Carroll, the new study described the potential treatment and has been published in the open-source preprint server bioRxiv*. Used as a nasal spray, it aims to boost the natural immune system of the body to fight common colds and flu. It works by triggering the innate immune system, which is the body’s first line of defense against infection from a pathogen. When the drug has enhanced the immune system, it also prevented the infection and replication of SARS-CoV-2 in the laboratory. The Study Respiratory tract diseases, including those that cause flu, common colds, and the coronavirus infection, represent major ongoing global health threats. These viruses have caused outbreaks to pandemics, endangering the lives of those who are at higher risk, such as children, older adults, and those who are immunocompromised. The SARS-CoV-2 infection is actively spreading worldwide, and it spreads quickly from one person to another through close contact and respiratory droplets. One of the biggest threats of the current pandemic is that several people infected with the virus are asymptomatic, which means that they do not know that they carry the virus. As a result, they are called silent spreaders. The research team from the National Infection Service, Public Health England (PHE) wanted to develop the nasal spray to prevent the replication of the virus in the nasal area, the most common point of entry of the virus. To test the nasal spray, the team obtained nasal wash and throat swab samples four days before the viral challenge. Upon analyzing the viral RNA in nasal wash samples, the team confirmed infection in all treatment groups, with lower viral RNA levels seen in the INNA-051 treatment. The team has found that prophylactic intra-nasal administration of INNA-051 in the SARS-CoV-2 ferret infection model has reduced levels of viral RNA in the nose and throat. “The results of our study support clinical development of a therapy based on prophylactic TLR2/6 innate immune activation in the URT to reduce SARS-CoV-2 transmission and provide protection against COVID-19,” the team wrote in the paper. Further, the research team added that the prophylactic approach is important to people at a high risk of community transmission or development of the severe disease from COVID-19, such as older adults, people with comorbidities, and those who are immunocompromised. “We’ve been amazed by just how effective our treatment has been. By boosting the natural immune response of the ferrets with our treatment, we’ve seen a rapid eradication of the virus,” Christophe Demaison, the Ena Respiratory Managing Director, said. “If humans respond similarly, the benefits of treatment are two-fold. Individuals exposed to the virus would most likely rapidly eliminate it, with the treatment ensuring that the disease does not progress beyond mild symptoms. This is particularly relevant to vulnerable members of the community. In addition, the rapidity of this response means that the infected individuals are unlikely to pass it on, meaning a swift halt to community transmission,” he added. *Important Notice bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. This article has been modified. To read the original article click here.

The post Australian Scientists Develop a Nasal Spray That Could Stop SARS-CoV-2 Infection appeared first on Amazing Health Advances.

fight infection Archives - Amazing Health Advances

When to See a Doctor for Swelling in the Arms or Legs

Australian Scientists Develop a Nasal Spray That Could Stop SARS-CoV-2 Infection