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Study Suggests Ergothioneine in Mushrooms Can Help Extend Your Lifespan

The AHA! Team — Tue, 03 Sep 2024 08:26:55 +0000

Zoey Sky via Natural News – Mushrooms are a great addition to many savory dishes. Research suggests the benefits offered by mushrooms go beyond the kitchen. Several studies have found that a compound in mushrooms can help extend the human lifespan. One recent study looked into the potential benefits of fungi-derived bioactive compounds on lifespan and health span. The study also highlighted the importance of finding interventions to minimize age-related diseases. Another study published in the Nutrition Journal investigated the health benefits of mushrooms. Researchers found that mushroom consumption is linked to a longer lifespan. They credited this benefit to mushrooms’ high content of ergothioneine, an antioxidant amino acid found in fungi and bacteria. While conducting the study, researchers reviewed data from the Centers for Disease Control and Prevention’s Third National Health and Nutrition Examination Survey. The 20-year prospective cohort study involved 15,000 participants. Results revealed that the people who included mushrooms in their diet had a 16 percent lower chance of early death. The researchers also discovered that consuming one serving of mushrooms per day instead of processed meat reduced the chances of dying prematurely from any cause by at least 35 percent. The research team explained that this benefit may be due to ergothioneine’s antioxidant, anti-inflammatory and neuroprotective effects. They also suggested that ergothioneine’s anti-aging properties could stem from its ability to protect against telomere shortening. Research shows ergothioneine has protective effects on telomeres Telomeres are usually described as protective “caps” for chromosomes. These long strings of delicate, elaborately folded DNA act like the protective plastic tips on shoelaces that help prevent fraying and damage. Longer telomeres are associated with better cellular health and are also usually linked with longevity. But telomeres naturally shorten over time, which makes them less able to preserve the structure of chromosomes. Shorter telomeres are linked with aging and chronic degenerative disease. In a study with participants over 60, those with shorter telomeres were three times more likely to die of heart disease than those with longer telomeres. They were also at least eight times more likely to die from infections. In another preliminary study published in the Journal of Dietary Supplements in 2022, a research team discovered that treating cells with ergothioneine for eight weeks alleviated telomere shortening from oxidative stress. They suggested that this can help potentially avoid mutations in DNA that could cause cancer. The researchers concluded that the results support “a potential role for ergothioneine in oxidative stress-related conditions and healthy aging.” Ergothioneine also supports longevity by helping to replenish and recycle glutathione, the body’s master antioxidant. Data also suggests that ergothioneine offers a valuable “trifecta” of anti-aging gifts: supporting longer telomeres, protecting DNA and recycling glutathione. Mushrooms can support optimal brain health In a separate study, scientists found that people over 60 were found to display lower levels of ergothioneine. They added that those over 60 with mild age-related cognitive impairment showed even sharper declines in this important amino acid. This is bad because ergothioneine, which helps protect brain cells from oxidative stress, is believed to help aging adults maintain healthy cognition and memory. Test tube and animal studies have indicated that ergothioneine may also help support memory by creating new neurons or brain cells. In a trial published in the Japanese Journal of Pharmacology, the research team gave both healthy adults and those with mild cognitive impairment a mushroom extract containing 5 mg of ergothioneine a day for 12 weeks. They found that the supplementation resulted in significant improvements in verbal memory, working memory and sustained attention for both the healthy and the mildly impaired volunteers. (Related: 6 Mushrooms you can eat to prevent cognitive impairment and reduce your dementia risk.) Aside from its anti-aging properties, ergothioneine also helps support a healthy immune system, promotes optimal cardiovascular function and supports healthy skin. Ergothioneine is even used in skincare serums and creams to reduce the appearance of fine lines and soothe redness and irritation. It is also used in products that help fight against damage and photoaging caused by ultraviolet radiation. Visit NaturalMedicine.news for more research about mushrooms and other superfoods. Watch the video below to learn about the health benefits of Organic Chaga Mushrooms. This video is from the Health Ranger Store channel on Brighteon.com. Sources include: NaturalHealth365.com PubMed.NCBI.NLM.NIH.gov Brighteon.com To read the original article, click here: https://www.naturalnews.com/2024-08-14-study-ergothioneine-mushrooms-help-extend-lifespan.html

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Amazing Science-Backed Benefits of Oleocanthal

AHA Publisher — Tue, 03 Aug 2021 07:00:55 +0000

Dr. Don Colbert – We all know that extra virgin olive oil is good for us. But what if most benefits of the Mediterranean Diet and olive oil are from a specific component of the oil? What if most of the olive oils sold in the United States don’t contain it? Does your olive oil measure up? Introducing the benefits of oleocanthal. Here’s what it is, what it does in the human body, and how to get yours today. What Is Oleocanthal? Oleocanthal (OC) is one of many phenols found in extra virgin olive oil (EVOO), and it is also known as deacetoxy-ligstroside aglycon. It was first identified as a minor phenolic compound in olives in 1993 (1). The amount of oleocanthal in EVOO varies due to the varieties of olives and different regions in which they are grown. Unfortunately, many commercial EVOO contains negligible or no-detectable OC(2). While all EVOO’s phenols are beneficial, it’s OC that produces amazing results. In fact, the benefits of oleocanthal range from supporting brain health to reducing inflammation to inhibiting the overgrowth of harmful cells. Science-Backed Benefits of Oleocanthal Most of the health benefits of OC are due to its potent anti-inflammatory and antioxidant actions. Oleocathal’s anti-inflammatory properties were first described in 2005 (3). At that time, scientists believed OC’s anti-inflammatory strength was similar to non-steroidal anti-inflammatory drugs (NSAID) like ibuprofen (4). In fact, OC provides anti-inflammatory benefits by inhibiting inflammatory enzymes called cyclooxygenase enzymes COX-1 and COX-2 in lab studies. These enzymes are part of the reaction that converts arachidonic acid into inflammatory prostaglandins and thromboxane (5,6). OC’s anti-inflammatory effects are dose-dependent. Amazingly, oleocanthal is as strong, or even stronger, than ibuprofen (5,7,8). A 2005 lab study reported that oleocanthal inhibited 41–57% of COX activity while the same amount of ibuprofen inhibited only 13–18% COX activity (5). And, oleocanthal does even more. Oleocanthal and Brain Health Recent animal studies indicate that OC supports brain health while we age and slows degeneration. How? OC disrupts β-amyloid oligomerization (synthesis) and protects against neurodegeneration (9). What’s more, OC inhibits proteins’ fibrillization, which can occur in degeneration (10, 11). In addition, OC promotes amyloid clearance by inducing gene expression of transport proteins. This is hugely beneficial in supporting brain health (12, 13). Oleocanthal and Healthy Cells The Mediterranean diet and olive oil consumption are specifically linked to better overall health and reduction in cell overgrowth (14, 15). Analyses have found that supplementing high-oleocanthal olive oil results in lower cell-overgrowth prevalence (16) and less-invasive cells (17). In fact, researchers have not found that OC specifically fights harmful cells’ lysosomes, causing cellular toxicity and death both in lab and animal studies as needed (18). Oleocanthal and Heart Health It’s widely accepted that olive oil is great for your heart. Studies results show the benefits of OC include healthy hearts. One study found that consuming oleocanthal for one week increased antiplatelet effects and aggregation in healthy men. This supports heart health and healthy blood flow (19). Another study tested 3 different varying concentrations of OC consumption on healthy men. Each consumed oleocanthal at random for one week. Researchers assessed the effect on platelet function 2 hours after ingestion. Concentrated OC significantly inhibited platelet aggregation, while those consuming olive oil with no oleocanthal did not show the same benefit. Interestingly, the latter oil still had the same total amount of phenols, mainly in the form of free tyrosol (20). Oleocanthal and Joint Health As described above, oleocanthal is a potent COX enzyme inhibitor. This is great news for those with stiff or inflamed joints. Not only does OC disrupt the production of inflammatory prostaglandins, but it also suppresses lipopolysaccharide (LPS)-induced nitric oxide (NO) production. These actions inhibit nitric oxide synthase gene expression (21). Nitric oxide is a key facet of joint inflammation. OC is a potent natural compound that can support healthy joints (13). How to Get Enough Oleocanthal It can be difficult to consume oleocanthal and receive the benefits of oleocanthal from modern olive oil. In fact, most commercial varieties don’t contain any detectable amounts. Luckily, you can now get a cost-effective, convenient form of concentrated oleocanthal. Introducing Dr. Colbert’s Oleocanthal Our supplement line has expanded to include this amazing antioxidant and anti-inflammatory compound. Introducing Dr. Colbert’s Oleocanthal (Powerful Antioxidant Concentrated from High-Phenolic Extra Virgin Olive Oil)! This powerful supplement contains 2250 milligrams of oleocanthal per serving in an easy-to-take form. It’s been formulated specifically to support brain, heart, and whole-body health. Get yours today! Bottom Line Looking to support your brain health? Heart health? Joint-health? Whole-body health? Oleocanthal is an amazing compound ready to do it all. If you don’t have a trusted source of proven high-oleocanthal extra-virgin olive oil, get Dr. Colbert’s Oleocanthal (Powerful Antioxidant Concentrated from High-Phenolic Extra Virgin Olive Oil) today! To read the original article click here. For more articles from Dr. Colbert click here.

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