reduced mortality Archives - Amazing Health Advances

A Moderate Level of Physical Activity Increases Breast Cancer Survival

AHA Publisher — Wed, 30 Nov 2022 08:00:25 +0000

Suchandrima Bhowmik via News-Medical – Physical activity may provide some level of protection against the development of breast cancer; however, the impact of physical activity following a breast cancer diagnosis remains unknown. Previous studies suggest that both strenuous and moderate exercise have comparable benefits on the incidence of breast cancer; however, there is limited data on survival outcomes. A recent letter published in the journal JAMA Network Open discusses the association of physical activity beyond essential everyday functions with the mortality risk among breast cancer survivors. About the Study The current study included post-menopausal breast cancer survivors who had received their initial diagnosis at least two years prior to the start of the study. More specifically, the study participants’ early-stage breast cancer diagnosis was provided between 1996 and 2012. Baseline interviews were conducted between August 1, 2013, and March 31, 2015. After that, the participants were followed up with until their death or when the study ended on April 30, 2022. The Fatigue Severity Inventory and the Godin-Shephard Leisure-Time Physical Activity Questionnaire (GSLTPAQ) was used to assess physical activity and leisure. Exercise patterns were categorized as insufficiently active, moderately active, and active at baseline based on exercise habits during a seven-day period. Physical Activity Reduces Risk of Death Due to Breast Cancer A total of 315 participants were included in the study, all women. The mean age at the interview was 71 years. A total of 217 participants were non-Hispanic White, 28 were Pacific or Asian Islander, 66 were African American or Black, and four were Hispanic. Unfortunately, five participants died within the follow-up period due to breast cancer. Mortality rates were 12.9 per 1,000 person-years (PY) for active participants, 32.9/1000 PY for insufficiently active participants, and 13.4/1000 PY for moderately active participants. Taken together, moderately active or active participants were associated with a 60% reduced risk of death compared to insufficiently active participants. Conclusions Taken together, these findings indicate that both active and moderately active women diagnosed with breast cancer were less likely to die from breast cancer as compared to entirely inactive participants. Thus, the care management plans for women diagnosed with breast cancer should incorporate physical activity to increase the likelihood of survival and improve their overall quality of life. A key limitation of the current study includes the lack of information on the participants’ daily diet habits. Furthermore, physical activity was self-reported by the participants and is subject to bias; therefore, future studies incorporating technological devices such as pedometers and heart rate monitors may be beneficial. Journal reference: Chen, L. H., Irwin, M. R., Olmstead, R., et al. (2022). Association of Physical Activity With Risk of Mortality Among Breast Cancer Survivors. JAMA Network Open. doi:10.1001/jamanetworkopen.2022.42660. To read the original article click here.

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Proper Nutrient Intake Promotes Longevity, Study Suggests

AHA Publisher — Mon, 08 Aug 2022 07:00:26 +0000

News Staff via NaturalHealth365 – We’ve all heard it’s important to take in enough vitamins, minerals, and other nutrients. A healthy, balanced diet is essential to looking and feeling your best. But how are longevity and diet related? Keep reading to find out how your nutrient intake can affect mortality risk. In fact, according to one study published in the Annals of Internal Medicine, the answer is quite interesting – with a catch. Can Nutrient Intake Promote a Longer Life? If you don’t consume enough nutrients, it could lead to health problems in the long run. But what about nutrition for longevity? This is what the Annals study sought to determine. Researchers tried to find out if there’s a link between adequate nutrient intake and reduced mortality. They followed 27,000 adults over the age of 20 from the United States over several years. Researchers questioned participants about their nutrient intake from both food and supplements. Nutrient intake was considered “adequate” when intake was at or above the estimated average requirements. They then looked for correlations between nutrient intake and mortality. The study concluded that adequate vitamin K and magnesium intake led to a lower risk of death than inadequate intake. Additionally, sufficient vitamin A, vitamin K, zinc, and copper intake appeared to lower heart disease risk. Supplements vs. Nutrients from Food … Which One Is Better? The study suggests nutrient intake may be linked to a lower risk of mortality. However, there was a caveat to these results. The reduced mortality risk was only seen with nutrients that came from food, not dietary supplements. Those who took nutrient supplements didn’t appear to have a decreased risk of mortality or heart disease. So it would seem that the best source of nutrients is the food you eat. Moreover, taking too much calcium in supplements was associated with higher cancer risk. So taking in more nutrients than necessary could actually be harmful to your health. How to Get the Most Nutrients in Your Diet? Of course, don’t misunderstand the message here; dietary supplements can be vital for those who can’t get enough intake through food alone. For example, people with certain health conditions or food allergies. Folic acid is an essential supplement for pregnant women as it helps prevent fetal birth defects. Nutrient supplements have their place when needed. Even if there’s no evidence that nutrient supplements increase longevity, nutrient supplements can significantly improve the quality of your life and may be necessary. Supplementing with essential nutrients like CoQ10, magnesium, and vitamin C is linked to better heart health. You can also up your nutrition intake through food by consuming lots of whole, organic meals. Some foods, like microgreens, are particularly rich in nutrients like zinc, vitamin B6, and magnesium. To strive for the best possible health, choose a diet packed with organic (chemical-free) vegetables, fruits, and non-toxic fats or protein. Whenever possible, minimize (or avoid) processed foods, grow your food or look for high-quality, locally sourced organic food. Undoubtedly, eating a balanced (clean) diet will help you live a long and healthy life. So try making some changes today … what have you got to lose? Sources for this article include: LiveScience.com ACPJournals.org

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Drug Saves 47 of 50 Severe Covid Patients in Trial

AHA Publisher — Mon, 29 Nov 2021 08:23:27 +0000

Abigail Klein Leichman via Israel21c – Israel’s Bonus BioGroup reports a survival rate of 94 percent (47 of 50) of the severe Covid-19 patients treated with its drug product MesenCure in a Phase II, multicenter clinical trial. Study results, soon to be published, show MesenCure treatment reduced study participants’ hospitalization period by about half compared to a control group. All these patients had life-threatening pneumonia and respiratory distress caused by Covid-19. The data shows that MesenCure treatment reduced mortality by about 70% compared with the control group. Only two of the first 30 severe Covid-19 patients treated with MesenCure died due to Covid-19 or its complications, while 14 of 60 similar patients in the control group died. MesenCure treatment shortened the hospitalization period of severe Covid-19 patients by eight days on average, a reduction of 45% relative to the control group. The experimental group included women and men aged 41.4 to 77.4. About 77% of the severe Covid-19 patients treated in three hospitals with MesenCure had one or more risk factors for poor prognosis: hypertension, hyperlipidemia, obesity and Type 2 diabetes. Most were treated during the fourth Covid-19 wave in Israel, dominated by the Delta strain. The control group received the current standard of care — anti-inflammatory drugs in combination with steroids. This regimen, according to Bonus BioGroup, reduces mortality in hospitalized Covid-19 patients only slightly, from 25.8% to 21.8%, indicating that MesenCure is four times more effective. “We are proud of our success in leading the world to be a safer place by developing a medication for severe Covid-19 patients, thereby dramatically reducing the threat to their lives,” said Dr. Shai Meretzki, CEO of Bonus BioGroup. “In less than two years from the epidemic outbreak, we are the first in the world to report an effective and significant treatment for severely ill patients.” According to a statement from Bonus BioGroup, an independent expert committee confirmed the findings of the Phase II clinical trial of MesenCure and recommended continuing toward Phase III. Meretzki told the Jerusalem Post that the company will apply for emergency use approval from European and US regulatory agencies. To read the original article click here.

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