prevent dementia Archives - Amazing Health Advances

Slash Risk of Dementia up to 40% with THIS Science-Backed Approach

The AHA! Team — Wed, 06 Aug 2025 05:03:21 +0000

Patrick Tims via NaturalHealth365 – Count to three. That’s how long it takes for someone in the world to develop dementia. The number of people living with this condition will double in just two decades. The good news? There are ways to defend against cognitive decline – nutrition, mental stimulation, and exercise, as highlighted in a study published in the British Journal of Sports Medicine. Aerobic exercise is one of the most powerful lifestyle factors for protecting brain health. Research shows that staying physically active can significantly lower the risk of dementia, making movement a key ingredient in lifelong cognitive wellness. So, how does exercise protect your brain? And what kind of workout is most effective? Let’s dive in. Exercise: A powerful defense against dementia The fight against dementia starts with movement. Research shows that high cardiorespiratory fitness (CRF) can lower the overall risk of dementia by 40% and even reduce risk by 35% in those genetically predisposed to the condition. Why? Because exercise strengthens both the heart and lungs, two key players in maintaining cognitive function. Drawing from the UK Biobank data, a new study analyzed over 61,000 adults aged 39 to 70 over 12 years. The findings were clear: Those with higher CRF performed significantly better on cognitive tests. Even individuals with a moderate to high genetic risk for dementia saw a 35% lower risk if they maintained high CRF. Participants with high CRF had a 40% lower overall risk of developing dementia. On average, they also delayed dementia onset by 1.5 years. CRF – your body’s ability to deliver oxygen during exercise – directly impacts memory, processing speed, and cognitive resilience. Just six minutes of stationary cycling was enough to reveal these benefits in the study. While no single factor can guarantee protection against dementia, regular aerobic exercise is one of the most powerful tools available for preserving brain health and reducing the impact of genetic risk. Not all exercise protects against dementia – cardio is key When it comes to brain health, not all exercise is created equal. Cardiorespiratory fitness (CRF) is one of the most effective physical activities for slowing cognitive decline. However, knowing that aerobic exercise is one of the most powerful defenses against dementia is one thing – making it a consistent habit is another. The key is finding activities that you enjoy and can sustain long-term. Here’s how to seamlessly integrate CRF-boosting movement into your lifestyle: 1. Start small and build up If you’re new to aerobic exercise, start with 10-15 minutes a day and gradually increase the duration and intensity. A brisk walk around the neighborhood, a light bike ride, or even a short dance session in your living room can get your heart pumping. 2. Make movement a daily habit Schedule exercise like an important meeting. Whether it’s a morning walk, an afternoon swim, or an evening dance class, consistency matters more than intensity. The goal is to keep your heart and lungs working regularly. 3. Try fun, social activities Exercising with others can make it more enjoyable and sustainable. Join a dance class, sign up for a group swim session, or go on weekend hikes with friends. Social engagement is a brain booster, so combining it with movement creates a double benefit. 4. Take advantage of everyday movement You don’t need a gym membership to stay active. Take the stairs instead of the elevator, park farther from the store, or walk while taking phone calls. Small bursts of movement throughout the day add up. 5. Mix it up to stay engaged Variety prevents boredom and ensures you’re challenging different muscle groups. Alternate between cycling, power walking, swimming, and dancing to keep things interesting while maximizing CRF benefits. 6. Track your progress Using a fitness tracker or journal to monitor your activity levels can help you stay motivated and see your improvement over time. Even tracking how you feel mentally and physically after exercise can reinforce the habit. 7. Listen to your body The goal is lifelong brain health, so prioritize consistency over intensity. If you’re fatigued, opt for a lower-impact activity like swimming or a leisurely bike ride instead of skipping movement altogether. By making these small but meaningful changes, you’re not just improving your physical health but actively protecting your brain for years to come. Sources for this article include: BMJ.com Studyfinds.org Alzint.org To read the original article click here.

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Antidepressants Linked to Faster Cognitive Decline in Dementia

The AHA! Team — Fri, 23 May 2025 05:21:22 +0000

Karolinska Institutet via EurekAlert! – New research suggests that antidepressants can accelerate cognitive decline in people with dementia. At the same time, some drugs appear to be less harmful than others, which can help doctors make better treatment decisions, according to the study published in BMC Medicine. Antidepressants are often used to relieve symptoms such as anxiety, depression, aggressiveness, and sleep disturbances in dementia sufferers. However, a new observational study based on data from the Swedish Dementia Registry (SveDem) shows that patients with dementia who are treated with antidepressants experience an increased cognitive decline compared to patients who do not receive this medication. The study is based on a comprehensive analysis of registry data from 18,740 patients, of whom approximately 23 percent were treated with antidepressants. During the course of the study, a total of 11,912 prescriptions of antidepressants were registered, with selective serotonin reuptake inhibitors (SSRIs) accounting for 65 percent. Depressive symptoms “Depressive symptoms can both worsen cognitive decline and impair quality of life, so it is important to treat them. Our results can help doctors and other healthcare professionals choose antidepressants that are better adapted for patients with dementia,” says Sara Garcia Ptacek, researcher at the Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, and the study’s last author. The researchers from Karolinska Institutet and Sahlgrenska University Hospital in Gothenburg have followed the patients’ cognitive development over time and compared both medicated and non-medicated groups as well as different types of antidepressants. Although it is not currently possible to determine whether the cognitive impairment is due to the drugs or to the depressive symptoms themselves, the researchers were able to see that antidepressants were associated with increased cognitive decline. Differences between drugs The study also points to differences between different drugs. The SSRI escitalopram was associated with the fastest cognitive decline, followed by the SSRIs citalopram and sertraline. Mirtazapine, which has a different mechanism of action, had less negative cognitive impact than escitalopram. The researchers now want to investigate whether certain patient groups, such as people with specific dementia types or biomarkers, respond better or worse to different antidepressants. “The goal is to find these subgroups to create more individualised care,” says Sara Garcia Ptacek. The study has been funded by the Swedish Research Council, Region Stockholm, the Swedish Dementia Research Foundation, the Alzheimer’s Foundation and New Innovative Roads Call – a private initiative from the Leif Lundblad family and others. The researchers report no conflicts of interest. Publication: “Antidepressant use and cognitive decline in patients with dementia: a national cohort study”, Minjia Mo, Tamar Abzhandadze, Minh Tuan Hoang, Simona Sacuiu, Pol Grau Jurado, Joana B. Pereira, Luana Naia, Julianna Kele, Silvia Maioli, Hong Xu, Maria Eriksdotter, Sara Garcia Ptacek. BMC Medicine, online February 25, 2025, doi: 10.1186/s12916-025-03851-3. Journal BMC Medicine DOI 10.1186/s12916-025-03851-3. To read the original article click here.

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Ancient Herb Shows Promise in Fighting Dementia

The AHA! Team — Mon, 16 Dec 2024 06:16:14 +0000

Osaka Metropolitan University via News-Medical – Attempts to discover a breakthrough dementia drug might be drawing attention these days, but traditional medicinal products can offer hints for preventive medicine. Traditional medicinal products can offer hints for preventive medicine A research group led by Specially Appointed Professor Takami Tomiyama of Osaka Metropolitan University’s Graduate School of Medicine has found that administering the dried seeds of a type of jujube called Ziziphus jujuba Miller var. spinosa, used as a medicinal herb in traditional Chinese medicine, holds promise in restoring cognitive and motor function in model mice. By administering hot water extracts of Zizyphi spinosi semen to model mice with Alzheimer’s disease, frontotemporal dementia, Parkinson’s disease, and dementia with Lewy bodies, the team found that cognitive and motor functions were restored. Furthermore, when the seeds were simply crushed into powder and administered to the model mice, the team discovered that the cognitive function of the model mice recovered to a level above that of control mice. In addition, the powders apparently suppressed cellular aging in older mice and improved their cognitive function to a similar level as younger mice. Previously, members of the research team reported separately that the pathology of dementia in model mice improved with cognitive and motor functions restored after using the Hawaiian herb mamaki and the Chinese herb Acorus gramineus. “The results of our research will hopefully make it possible to develop dementia prevention products that middle-aged and elderly people can take at their own discretion.” -Takami Tomiyama, Professor, Graduate School of Medicine, Osaka Metropolitan University The findings are currently available as a reviewed preprint in eLife. Source: Osaka Metropolitan University Journal reference: Umeda, T., et al. (2024) Simply crushed Zizyphi spinosi semen prevents neurodegenerative diseases and reverses age-related cognitive decline in mice. doi.org/10.7554/elife.100737.1. To read the original article click here.

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Nanoplastics Promote Conditions for Parkinson’s Across Various Lab Models

The AHA! Team — Mon, 26 Aug 2024 03:47:42 +0000

Duke Health – DURHAM, N.C. – A novel study sounds the alarm on the need for a new area of research. Nanoplastics interact with a particular protein that is naturally found in the brain, creating changes linked to Parkinson’s disease and some types of dementia. In a Duke-led study appearing Nov. 17 in Science Advances, the researchers report that the findings create a foundation for a new area of investigation, fueled by the timely impact of environmental factors on human biology. Improperly disposed plastics have been shown to break into very small pieces “Parkinson’s disease has been called the fastest growing neurological disorder in the world,” said principal investigator, Andrew West, Ph.D., professor in the Department of Pharmacology and Cancer Biology at Duke University School of Medicine. “Numerous lines of data suggest environmental factors might play a prominent role in Parkinson’s disease, but such factors have for the most part not been identified.” Improperly disposed plastics have been shown to break into very small pieces and accumulate in water and food supplies, and were found in the blood of most adults in a recent study. “Our study suggests that the emergence of micro and nanoplastics in the environment might represent a new toxin challenge with respect to Parkinson’s disease risk and progression,” West said. “This is especially concerning given the predicted increase in concentrations of these contaminants in our water and food supplies.” West and colleagues in Duke’s Nicholas School of the Environment and the Department of Chemistry at Trinity College of Arts and Sciences found that nanoparticles of the plastic polystyrene — typically found in single use items such as disposable drinking cups and cutlery — attract the accumulation of the protein known as alpha-synuclein. West said the study’s most surprising findings are the tight bonds formed between the plastic and the protein within the area of the neuron where these accumulations are congregating, the lysosome. Researchers said the plastic-protein accumulations happened across three different models performed in the study – in test tubes, cultured neurons, and mouse models of Parkinson’s disease. West said questions remain about how such interactions might be happening within humans and whether the type of plastic might play a role. And were found in the blood of most adults in a recent study “While microplastic and nanoplastic contaminants are being closely evaluated for their potential impact in cancer and autoimmune diseases, the striking nature of the interactions we could observe in our models suggest a need for evaluating increasing nanoplastic contaminants on Parkinson’s disease and dementia risk and progression,” West said. “The technology needed to monitor nanoplastics is still at the earliest possible stages and not ready yet to answer all the questions we have,” he said. “But hopefully efforts in this area will increase rapidly, as we see what these particles can do in our models. If we know what to look out for, we can take the necessary steps to protect ourselves, without compromising all the benefits we reap every day from plastics.” The study was funded by in part by The Michael J. Fox Foundation for Parkinson’s Research and the Aligning Science Across Parkinson’s initiative (ASAP-020527). In addition to West, study authors include Zhiyong Liu, Arpine Sokratian, Addison M. Duda, Enquan Xu, Christina Stanhope, Amber Fu, Samuel Strader, Huizhong Li, Yuan Yuan, Benjamin G. Bobay, Joana Sipe, Ketty Bai, Iben Lundgaard, Na Liu, Belinda Hernandez, Catherine Bowes Rickman, and Sara E. Miller. To read the original article click here.

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Indian Spice Cuts Dementia Risk by 40%

The AHA! Team — Mon, 13 May 2024 08:01:26 +0000

Al Sears, MD, CNS – By age 60, you have a 50/50 chance of having a clinically enlarged prostate. And it only gets worse every year. When your prostate isn’t functioning properly, it’s hard to enjoy life. There is a new study from Harvard University that demonstrates the power of special plant compounds called flavonoids. It reinforces the advice I’ve been giving my patients for more than 30 years… Increasing your intake of specific nutrients can head off – and even reverse – early signs of memory loss. The Harvard researchers came to this conclusion after tracking the dietary habits and cognitive outcomes of 78,000 study participants for 20 years. They found that those with a high intake of certain flavonoids were almost 40% less likely to experience cognitive decline.1 While it’s not entirely clear how flavonoids protect your memories, researchers believe the antioxidant and anti-inflammatory properties of these plant metabolites are in play. But what is clear is that dementia and other forms of cognitive decline are not due to the “Alzheimer’s gene” (APOE-e4) or any other aspect of your DNA. It’s another strong indication genes aren’t to blame for the 110% increase in Alzheimer’s that’s projected to happen by 2050. As a regular reader, you know Big Agra’s endless production of processed carbs is the key cause of Alzheimer’s. Our bodies simply weren’t designed for the industrial, grain-based foods modern humans eat. This starchy diet touches off an inevitable cascade of insulin resistance, inflammation, weight gain, and cellular damage. And it’s one reason a growing number of researchers are beginning to refer to Alzheimer’s as “type 3 diabetes.”2 But I see a bright side to the Harvard study. It supports the message I’ve been sharing with my patients for years now… With the right nutrients, you CAN protect yourself from this terrible disease. Why Your Brain Wants You to “Eat the Rainbow” I encourage my patients to “eat the rainbow.” Flavonoids give fruits and vegetables their bright, rainbow-like colors. Think of red and green peppers, purple grapes, blackberries, strawberries, blueberries, carrots, oranges, grapefruit, and so forth. Other food sources of flavonoids include onions, celery, artichokes, and broccoli – as well as spices like parsley and oregano. But given the increasingly alien environment we live in, there’s one brain-protective flavonoid that stands above the rest. And I recommend all my patients include it in their diet. I’m talking about curcumin. Curcumin is the bright compound that gives turmeric it’s unique golden color. Studies show it contributes to significant memory improvement and stronger cognitive function. Turmeric is the ingredient that gives curry its savory, earthy taste. It’s a member of the ginger family. Some researchers believe the heavy curry consumption in rural India explains the low incidence of dementia there. It’s only about a third of the rate seen in Europe and the United States.3 Protect Your Brain with Indian Curry My family loves to make curry. Here’s one of our favorite recipes: Ingredients: 1 teaspoon coconut oil 4 boneless chicken thighs, cut into small pieces 2 cups diced yellow onion 2 cloves garlic, minced 2 tablespoons fresh ginger 6 two-inches pieces of fresh turmeric root, peeled and grated 1 1/2 teaspoons ground cumin 1 teaspoon ground coriander 1/2 teaspoon ground cardamom 1 can (13.6) ounces of coconut milk 1 cup chicken stock 1/2 teaspoon garam masala 4 cups cubed butternut squash 1 tablespoon lime juice Instructions: Sauté chicken in coconut oil until cooked, then remove and set aside. Sauté the onion until it begins to soften. Then add ginger and garlic. Add remaining spices and cook for about 30 seconds. Add the butternut squash, coconut milk, and broth. Simmer for 15 minutes. Add salt to taste along with freshly squeezed lime juice. Add chicken and serve. To Your Good Health, Al Sears, MD, CNS References: 1. Yeh, Tian-Shin, et al. “Long-term dietary flavonoid intake and subjective cognitive decline in US men and women.” Neurology. 2021 Sept;97(10):e1041 – e1056. 2. de la Monte S, and Wands R. “Alzheimer’s disease is type 3 diabetes: Evidence reviewed.” J Diabetes Sci Technol. 2008 Nov; 2(6): 1101–1113. 3. Chandra V, et al. “Incidence of Alzheimer’s disease in a rural community in India: The Indo-US Study.” Neurology. 2001 Sep 25;57(6):985-9. To read the original article click here.

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Greater Body Fat Found to Be a Risk Factor for Reduced Cognitive Function

AHA Publisher — Wed, 02 Feb 2022 08:00:54 +0000

McMaster University via News-Medical – A new study has found that greater body fat is a risk factor for reduced cognitive function, such as processing speed, in adults. Even when the researchers took cardiovascular risk factors (such as diabetes or high blood pressure) or vascular brain injury into account, the association between body fat and lower cognitive scores remained. This suggests other not yet confirmed pathways that linked excess body fat to reduced cognitive function. In the study, 9,166 participants were measured by bioelectrical impedance analysis to assess their total body fat. As well, 6,733 of the participants underwent magnetic resonance imaging (MRI) to measure abdominal fat packed around the organs known as visceral fat, and the MRI also assessed vascular brain injury – areas in the brain affected by reduced blood flow to the brain. The results were published today in JAMA Network Open. “Our results suggest that strategies to prevent or reduce having too much body fat may preserve cognitive function.” Sonia Anand, lead author, professor of medicine of McMaster University’s Michael G. DeGroote School of Medicine and vascular medicine specialist at Hamilton Health Sciences (HHS) She is also a senior scientist of the Population Health Research Institute of McMaster and HHS. She added that “the effect of increased body fat persisted even after adjusting for its effect on increasing cardiovascular risk factors like diabetes and high blood pressure, as well as vascular brain injury, which should prompt researchers to investigate which other pathways may link excess fat to reduced cognitive function.” Co-author Eric Smith, a neurologist, scientist and an associate professor of clinical neurosciences at the University of Calgary, said that “preserving cognitive function is one of the best ways to prevent dementia in old age. This study suggests that one of the ways that good nutrition and physical activity prevent dementia may be by maintaining healthy weight and body fat percentage.” Smith is head of the brain core lab for the two population cohorts used for this new analysis– the Canadian Alliance for Healthy Hearts and Minds (CAHHM) and PURE Mind- a sub-study of the large, international Prospective Urban Rural Epidemiological (PURE) study. The participants were in the age range of 30 to 75 with an average age of about 58. Just over 56% were women; they all lived in either Canada or Poland. The majority were White European origin, with about 16% other ethnic backgrounds. Individuals with known cardiovascular disease were excluded. To read the original article click here.

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