newborn baby Archives - Amazing Health Advances

Postpartum Female Preference for Cooler Temperatures Linked to Brain Changes

The AHA! Team — Mon, 11 Aug 2025 05:35:50 +0000

Baylor College of Medicine via EurekAlert! – Mothers experience major metabolic adaptations during pregnancy and lactation to support the development and growth of the new life. Although many metabolic changes have been studied, body temperature regulation and environmental temperature preference during and after pregnancy remain poorly understood. Researchers at Baylor College of Medicine and collaborating institutions show in the journal Molecular Metabolism that postpartum female mice develop new environmental temperature preferences and reveal brain changes mediating these changes. Humans and mice body temperature “In both humans and mice, body temperature increases during early pregnancy, drops to normal temperature during late pregnancy and then goes up again during lactation,” said co-corresponding author Dr. Chunmei Wang, assistant professor of pediatrics at USDA/ARS Children’s Nutrition Research Center at Baylor. In this study, Wang and her colleagues investigated what changes occurred in the brain that mediated the new temperature preference. “We worked with mice and found that female mice prefer a cooler environment starting from late pregnancy and persisting in long-term postpartum,” Wang said. “For more than four weeks post-weaning female mice had a lower body temperature and preferred cooler environments; they lost their typical preference for warm environments (30 °C/86 °F) but still avoided cold environments (15 °C/59 °F).” To identify the biological underpinnings of these changes, the researchers studied the preoptic area (POA), a brain region important for sensing and regulating body temperature. “We discovered that the change in temperature preference in postpartum female mice was associated with a significant decrease in a particular group of neurons, estrogen receptor alpha (ERα)-expressing neurons in the preoptic area of the brain (ERαPOA neurons),” Wang said. Supporting this finding, the researchers found that virgin females in which the estrogen receptor alpha had been deleted in ERαPOA neurons also preferred lower temperatures and avoided warmer locations, mimicking postpartum females. Looking closely into the ERαPOA neurons, the researchers found that these neurons vary in their ability to sense warm or cold temperatures – one group of ERαPOA neurons can directly respond to warmth, while another group responds to cooler temperatures. “Interestingly, compared to female mice that had not been pregnant, ERαPOA neurons of postpartum females had reduced response to warmth and an enhanced response to cold,” Wang said. Together, the results support that the ability of ERαPOA neurons to sense warmth and cold is regulated by reproductive experience and leads to changes in temperature preferences that alter the animal’s warmth-seeking behavior. Currently, the researchers are exploring the function of each group of ERαPOA neurons on the regulation body temperature and thermal preference. Other contributors to this work include Nan Zhang, Meng Yu, Qianru Zhao, Bing Feng, Yue Deng, Jonathan C. Bean, Qingzhuo Liu, Benjamin P. Eappen, Yang He, Kristine M. Conde, Hailan Liu, Yongjie Yang, Longlong Tu, Mengjie Wang, Yongxiang Li, Na Yin, Hesong Liu, Junying Han, Darah Ave Threat, Nathan Xu, Taylor Smiley, Pingwen Xu, Lulu Chen and co-corresponding authors Tianshu Zeng and Yanlin He. The authors are affiliated with one or more of the following institutions: Baylor College of Medicine, Huazhong University of Science and Technology, Hubei Branch of National Center for Clinical Medical Research of Metabolic Diseases, Louisiana State University, South-central Minzu University and the University of Illinois. This work was supported by grants from the USDA/CRIS (3092-51000-062-04(B)S), Pennington Biomedical Research Center institutional funding and the National Natural Science Foundation of China. ### Journal Molecular Metabolism DOI 10.1016/j.molmet.2025.102108 To read the original article click here.

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What Parents Should Know About Newborn Hearing Screenings

The AHA! Team — Wed, 11 Jun 2025 05:09:29 +0000

Children’s Hospital Los Angeles via Newswise – Early detection of hearing loss in children is imperative. Learn what the result of your kid’s hearing test means—and what you need to do about it next. In the United States, approximately 3 out of every 1,000 infants are born with hearing loss. Surprisingly, over 90% of these children are born to parents who themselves have normal hearing. As mandated by state regulations, newborn hearing screenings are performed in all hospitals where babies are delivered. These screenings are essential for early detection, which Kristina Rousso, AuD, an audiologist with the California Leadership Education in Neurodevelopmental and Related Disabilities (CA-LEND) training program at Children’s Hospital Los Angeles, says is crucial for achieving optimal outcomes in a child’s development. Babies’ brains “From birth, babies’ brains are constantly taking in information to support development of listening, language, and reading,” Dr. Rousso says. Dr. Rousso says that she and her colleagues follow the Joint Committee on Infant Hearing Guidelines 1:3:6 model—identification through screening by 1 month of age; diagnosis of hearing level and type with a pediatric audiologist by 3 months of age; and treatment with hearing devices by 6 months of age. What can cause hearing loss at birth? Below are some of the reasons that a baby may be born with hearing loss: Genetic factors Maternal viruses during pregnancy, such as cytomegalovirus (CMV) and rubella Extended stays in neonatal intensive care, due to risk factors such as low birth weight, lack of oxygen, and phototherapy treatment Two types of newborn hearing screenings There are two primary types of newborn hearing screenings: otoacoustic emissions (OAE) and auditory brainstem response (ABR). “Both are painless, fast, and easy to measure,” Dr. Rousso says. Otoacoustic emissions involves playing different sounds into the baby’s ear to detect a response from the inner ear Auditory brainstem response measures the brain’s response to sounds and volume levels through electrodes placed on the baby’s head during sleep. Hearing screenings provide a “pass” or “refer” result. Here is what each means. Pass: A “pass” indicates your baby likely has normal to near-normal hearing. “However,” Dr. Rousso says, “it’s still important to monitor speech and language development and the baby’s responses to different sounds in the environment.” If your baby does not respond to sounds appropriately at home, or their speech and language development is not advancing, schedule a hearing test appointment with a pediatric audiologist, who can evaluate and treat your child for possible hearing loss. Refer: A ”refer” result means that more information is needed to determine if the baby has hearing loss in one or both ears. A second hearing test will be administered before you and your baby are discharged. If the baby does not pass the second time, you will be referred to a pediatric audiologist for a comprehensive diagnostic evaluation. Dr. Rousso emphasizes the importance of promptly taking your baby to a pediatric audiologist for a complete evaluation if the baby does not pass the hearing screen, or if the baby is not developing speech or language. The sooner hearing loss is diagnosed and treated, the faster a baby’s brain can start to develop speech and language. To read the original article click here.

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Doctors Perform Lifesaving Procedure on Baby During Birth

AHA Publisher — Fri, 16 Oct 2020 07:00:42 +0000

Abigail Klein Leichman via Israel21c – Doctors in Israel saved a newborn’s life yesterday with a rare surgical procedure performed before the boy was fully outside his mother’s body. The “ex utero intrapartum treatment” (EXIT) procedure during a Caesarean-section delivery at Tel Aviv Sourasky Medical Center was planned when prenatal imaging revealed that the fetus’ airways were blocked by a growth. They knew the fetus would be fine until his umbilical cord was cut because the placenta provides oxygen. Once the cord is detached after birth, he would not have been able to breathe air into his lungs. A team of some 30 physicians prepared for the EXIT procedure – previously done in Israel only a few times — using a 3D-printed model of the fetus’ neck. The multidisciplinary team of doctors and nurses delivered the baby’s head and inserted a tracheal tube that bypassed the growth. When they pulled the rest of his body from the womb and cut the cord, he was able to breathe through the tube. Mother and son are reported to be in good condition. The doctors believe the airway-blocking growth may disappear on its own; otherwise it can be surgically removed. ′′I’ve been an obstetrician for over 25 years and every birth is a new source of excitement, but this was one of the special ones,” said Dr. Ariel Many, director of labor and delivery at the center’s Lis Maternity and Women’s Hospital. “To be a partner in a procedure where you’re holding the head of the fetus and treating him while he is mostly still in his mother’s womb, and then delivering this new life into the world, is a supreme, uplifting, special and touching feeling that will stay with me and the team for a long time,′′ said Many. To read the original article click here. For more articles from Israel21c click here.

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