natural antibodies Archives - Amazing Health Advances https://amazinghealthadvances.net/tag/natural-antibodies/ Your hub for fresh-picked health and wellness info Fri, 15 Nov 2024 03:36:15 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.1 https://amazinghealthadvances.net/wp-content/uploads/2019/08/AHA_Gradient_Bowl-150x150.jpg natural antibodies Archives - Amazing Health Advances https://amazinghealthadvances.net/tag/natural-antibodies/ 32 32 Breast Milk Antibodies Linked to Protection Against Rotavirus in Infants https://amazinghealthadvances.net/breast-milk-antibodies-protection-against-rotavirus-in-infants-8349/#utm_source=rss&utm_medium=rss&utm_campaign=breast-milk-antibodies-protection-against-rotavirus-in-infants-8349 https://amazinghealthadvances.net/breast-milk-antibodies-protection-against-rotavirus-in-infants-8349/#respond Fri, 08 Nov 2024 06:40:26 +0000 https://amazinghealthadvances.net/?p=16550 University of Rochester Medical Center via News-Medical – Babies whose mothers had high levels of specific antibodies in their breast milk were able to fend off the infection for a longer period than infants whose mothers had lower levels. A study led by researchers at the University of Rochester Medical Center found that breast milk provides protection against rotavirus, a common gastrointestinal disease that causes diarrhea, vomiting and fever in infants. Babies whose mothers had high levels of specific antibodies in their breast milk were able to fend off the infection for a longer period than infants whose mothers had lower levels. The findings are expected to drive future research to improve infant health through optimized breastfeeding practices. Published in the Journal of Clinical Investigation and funded by the Bill and Melinda Gates Foundation, the study also found significant differences in antibody profiles in breast milk between mothers in high-income countries (HICs) and low- and middle-income countries (LMICs). Researchers analyzed human milk samples from 695 women in Finland, the U.S., Pakistan, Peru, and Bangladesh, and measured specific IgA and IgG antibodies, which are common antibodies produced in breast milk, against 1,607 proteins from 30 pathogens. Researchers analyzed human milk samples from 695 women in Finland, the U.S., Pakistan, Peru, and Bangladesh The research, led by Dr. Kirsi Jarvinen-Seppo, MD, PhD, professor in the Division of Allergy and Immunology at UR Medicine Golisano Children’s Hospital (GCH), tracked antibody levels and kinetics over time to analyze antibody responses to a wide range of respiratory, diarrheal and sepsis pathogens in human milk. The study’s primary aim was to understand the protective properties of these antibodies and how they vary across different geographic and economic regions. “We would expect to find differences in antibody levels in different countries, due to different diseases circulating among areas of the world, but this is one of the first times that there’s been a head-to-head comparison for dozens of pathogens across several continents. It was encouraging to see such a clear link between higher antibody levels and a delay to rotavirus infection, and this was consistently observed among an independent validation cohort.” Dr. Kirsi Jarvinen-Seppo, MD, PhD, Professor in the Division of Allergy and Immunology at UR Medicine Golisano Children’s Hospital (GCH) Other notable findings from the study: Milk from women in LMICs had higher levels of IgA and IgG antibodies against various intestinal and respiratory pathogens compared to milk from HICs. This difference was particularly notable for pathogens such as Shigella and pneumococcus, which are major contributors to morbidity and mortality in young children. Higher body mass index (BMI) was associated with lower antibody levels, which went against expectations. “The variation in antibody profiles between regions highlights the impact of economic and environmental factors on maternal immunity,” said Jarvinen-Seppo. In addition to Rotavirus findings, the discovery that a higher BMI was associated with lower antibody counts in breast milk was also unexpected. “We had anticipated that underweight mothers might have lower antibody levels due to poorer nutritional status,” said Jarvinen-Seppo. “Due to rising obesity rates worldwide, this could be a significant finding, but this is preliminary and additional research is needed since this is the first time this has been measured.” “While the data on rotavirus protection is compelling, the geographical and BMI-related variations highlight areas where further research is essential. The study sets the stage for additional investigations that could lead to better understanding and interventions for improving infant health globally,” said Jarvinen-Seppo. Source: University of Rochester Medical Center Journal reference: Campo, J. J., et al. (2024). Human milk antibodies to global pathogens reveal geographic and interindividual variations in IgA and IgG. Journal of Clinical Investigation. doi.org/10.1172/jci168789. To read the original article click here.

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]]> https://amazinghealthadvances.net/breast-milk-antibodies-protection-against-rotavirus-in-infants-8349/feed/ 0 Natural COVID-19 Antibodies Lasts Seven Months for Children, According to New Study https://amazinghealthadvances.net/natural-covid-19-antibodies-lasts-seven-months-for-children-7902/#utm_source=rss&utm_medium=rss&utm_campaign=natural-covid-19-antibodies-lasts-seven-months-for-children-7902 https://amazinghealthadvances.net/natural-covid-19-antibodies-lasts-seven-months-for-children-7902/#respond Mon, 28 Mar 2022 07:25:43 +0000 https://amazinghealthadvances.net/?p=14322 University of Texas Health Science Center at Houston via Newswise – Children previously infected with COVID-19 develop natural circulating antibodies that last for at least seven months, according to a new study led by researchers at UTHealth Houston. The study was published today in Pediatrics. Researchers examined data from 218 children across the state of Texas between the ages of 5 and 19 who were enrolled in the Texas CARES survey, which began in October of 2020 with the goal of assessing COVID-19 antibody status over time among a population of adults and children in Texas. Volunteers who enrolled in the study provided researchers with three separate blood draws. Samples were collected before the vaccine rollout and during the Delta and Omicron variants. To date, investigators have completed three different phases of the study. “This is the first study from the Texas CARES survey that includes data from all three time points in the survey,” said Sarah Messiah, PhD, MPH, corresponding author of the study and professor of epidemiology, human genetics, and environmental sciences at UTHealth School of Public Health Dallas campus. “These findings are important because the information we collected from children infected with COVID-19 didn’t differ at all by whether a child was asymptomatic, severity of symptoms, when they had the virus, were at a healthy weight or had obesity, or by gender. It was the same for everyone.” While 96% of those infected with COVID-19 continued to have antibodies up to seven months later, well over half (58%) of the sample were negative for infection-induced antibodies at their third and final measurement. The findings do not include the impact of vaccine protection. The results of Texas CARES, Messiah said, are just a step in understanding the virus’s impact on children. To date, 14 million kids in the U.S. have tested positive for the virus, she said. To read the original article click here.

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