Hormones Archives - Amazing Health Advances

Scientists Warn: Men’s Cancer Deaths Predicted to Soar by 93% by 2050

The AHA! Team — Wed, 29 Jan 2025 06:53:51 +0000

News Staff via NaturalHealth365 – Cancer is a diagnosis nobody wants to receive – it’s terrifying. While cancer rates have steadily climbed for most types, deaths from cancer have gone down. That’s good news, but it’s not the whole story. Few epidemiological studies have examined cancer cases versus deaths from the disease, so researchers have decided to investigate this gap. They focused on men’s cancer rates versus mortality, mainly because men’s cancer risk factors tend to be more controllable than women’s or children’s. What they found is concerning, but there is hope. We’ll look at their results and methods, what we can expect for men’s cancer rates going forward, and what you can do to lower your risks. Men’s cancer rates: A growing but preventable crisis The study we’re looking at was conducted in 2022 when cancer incidence was about 212 per 100,000 men surveyed. While this might not sound like a huge number, it is significant – and the research suggests these numbers could jump by up to 93% by 2050. Generally speaking, women face certain cancer risks due to their biology. The hormonal changes they experience throughout life make them more susceptible to cancers men simply don’t have to worry about – either because men lack ovaries and a uterus or because they don’t go through the same hormonal shifts. Men, however, have a different problem: they tend to make riskier lifestyle choices and pay less attention to their health than women, driving up their cancer rates for largely preventable reasons. While men don’t face the risks of breast, uterine, ovarian, or other female reproductive cancers, they tend to smoke more, drink more, and make poorer lifestyle choices than women, including bad diet and lack of exercise. These factors account for a huge portion of cancer rates – and they’re largely preventable. Are men’s cancer rates rising faster than we can handle? The researchers analyzed global epidemiological data to develop what they call an MIR (mortality to incidence ratio). They hypothesized that men in societies with lower Human Development Index (HDI) scores would have a much closer MIR to men in higher HDI countries. This makes sense – poor access to medical care, low socioeconomic status, war, disease, famine, and social unrest create low HDI societies. At the same time, countries like Australia, the U.S., and most of Europe rank higher on the HDI scale. They collected statistical data on males across several age groups: 15 to 64, 15 to 39, 40 to 64, and 65 and older. By sampling these diverse age groups and breaking them down by HDI status, they could better understand mortality versus incidence rates. The researchers then used this data to project men’s cancer rates 25 years into the future, assuming current societal conditions remained unchanged. The results were troubling. In low and medium HDI countries, the MIR was significantly closer – meaning cancer rates and deaths from cancer were nearly matched. Higher HDI countries showed high cancer incidence but lower mortality rates. This difference partly stems from richer countries having more access to cancer-promoting lifestyles, but researchers also noted better diagnostic capabilities in countries with stronger healthcare systems. One of the study’s most striking findings focused on men over 65, who showed the highest mortality rates when diagnosed with almost any type of cancer, especially rare ones like pancreatic or unusual blood cancers. The researchers suggested this might be because older men are less likely to seek treatment, have lower treatment tolerance, or lack access to necessary care due to economic factors. What the study says about men’s cancer rates The study projects a nearly 93% increase in men’s cancer rates by 2050 if current trends and variables remain unchanged. It emphasizes the critical role of wealthier nations in supporting poorer countries to strengthen global cancer diagnosis and treatment. The researchers advocate for creating a robust network of interconnected medical data sharing to improve outcomes worldwide. How to lower your cancer risk: Simple steps every man can take As research shows, men’s cancer risks often stem from preventable factors we impose on ourselves. Men are more likely to use tobacco and alcohol, engage in risky behaviors, maintain poor diets, live sedentary lifestyles, and work jobs with carcinogen exposure. We’re also less likely than women to see doctors and often ignore cancer symptoms for months – choices that can seriously impact treatment success. Nature offers many tools to fight disease, though we often overlook these natural protections. Quit smoking – period. There’s no benefit to smoking, only downsides. Lung cancer has the highest incidence and mortality rate for men worldwide, with smoking as a leading cause. Monitor alcohol intake. While moderate drinking might be okay, most men drink more than safe amounts. Excessive drinking doesn’t just harm your liver and heart – it increases cancer risk across the board. Your diet matters enormously in cancer prevention. Add cancer-fighting foods like organic walnuts, black beans, turmeric, chilies, and ginger. Increase your fruit and vegetable intake while removing processed foods. These changes particularly help prevent colon cancer. Exercise regularly – it helps trigger death in damaged cells. Consider beneficial supplements like ashwagandha, curcumin, vitamin D, and green tea. These have shown promising results in cancer prevention. Manage stress through regular exercise and meditation. High stress causes inflammation, which can promote cancer development. Make stress management a priority in your daily routine. Cancer rates are rising, but you can take action now to lower your risk. Many of these changes aren’t about adding new habits but stopping harmful ones. Taking charge of your health brings multiple benefits: lower blood pressure, reduced cardiovascular disease risk, less inflammation, and better overall well-being. Don’t make it easier for disease to take hold – start protecting your health today. Editor’s note: Discover the best ways to naturally avoid the threat of cancer from many of the best holistic cancer experts, own the Stop Cancer Docu-Class created by NaturalHealth365 Programs. Sources for this article include: Wiley.com To read the original article click here.

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What You Need to Know About Pituitary Tumors

The AHA! Team — Mon, 16 Dec 2024 06:33:20 +0000

Morgan deBlecourt via Duke Health – Pituitary tumors are abnormal growths in the pituitary gland, a pea-sized organ at the base of the brain that regulates hormones. Fortunately, these tumors are usually treatable and non-cancerous. Duke Health neurosurgeon Jordan Komisarow, MD, is part of a team of doctors who specialize in diagnosing and treating pituitary tumors. Here he answers frequently asked questions to help you decide where you should seek care. How serious is a pituitary tumor? Pituitary tumors are slow-growing and rarely life-threatening. According to Dr. Komisarow, many people find out they have a pituitary tumor accidentally, after undergoing an imaging scan for an unrelated problem. They often have no symptoms. On the other hand, pituitary tumors that are large can affect your vision. A subset of tumors produce harmful hormones and can significantly impact your quality of life. Regardless, all pituitary tumors should be managed by an experienced team of specialists to avoid serious complications. How can a pituitary tumor affect the rest of my body? Since the pituitary gland produces hormones, a pituitary tumor can affect any body system that involves hormones, including growth, metabolism, and reproduction. Symptoms can vary widely from fatigue to weight gain, infertility, sexual dysfunction, breast discharge, uncontrolled diabetes and blood pressure, and more. Large pituitary tumors can crowd nearby brain structures like the optic nerves, which can cause symptoms such as vision loss. What are the most common treatments for a pituitary tumor? If your pituitary tumor is low-risk and causing few or no symptoms, your best option may be to monitor the tumor with regular imaging and hormone testing, said Dr. Komisarow. Medications can help treat hormone imbalances. Surgery to remove the tumor is usually reserved for people experiencing significant symptoms or complications related to the tumor. What doctors treat pituitary tumors? Many types of doctors treat pituitary tumors since they can affect so many body functions. Even if you’re not a candidate for surgery, a neurosurgeon often serves as the point person for pituitary tumor care. Endocrinologists manage hormones and treat any resulting pituitary disorders. Neuro-ophthalmologists, eye doctors who specialize in treating vision problems caused by neurological conditions, treat vision loss. Other specialists who may be involved in your care include ear, nose, and throat (ENT) doctors, radiation oncologists, and plastic surgeons. Where should I go for pituitary tumor treatment? Dr. Komisarow recommends seeking treatment at a center like Duke, which offers an all-in-one pituitary clinic. This means you’ll see a neurosurgeon, endocrinologist, and neuro-ophthalmologist, all in one day and in one location. They offer comprehensive testing, review your test results, and discuss next steps. “You want to find doctors who specialize in treating pituitary tumors, meaning it’s not just a component of their practice, but it’s the center of their practice,” Dr. Komosarow said. “Especially if you need surgery, our team at Duke has the experience and technology to safely care for people that other institutions turn away due to risk of anesthesia or nerve damage. We want to help every patient we can.” To read the original article click here.

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Cystic Acne Treatment Through Dietary Changes & Beyond

The AHA! Team — Wed, 13 Nov 2024 06:11:16 +0000

Annie Price, CHHC via Dr. Axe – Have you ever had large, red, painful breakouts? These cystic acne breakouts can affect both men and women as young as 8 or as old 50. The face is the most common and concerning area of occurrence, but other problem areas can include the chest, back, upper arms and shoulders. Cystic acne, which is way worse than just any old pimple, is actually the most severe form of acne possible. Common medical treatment for cystic acne might work, but some have very serious side effects. A natural way to fight cystic acne is to address the gut-skin connection with the use of probiotics through food, supplements and home remedies for acne. In fact, way back in 1961, a case report found that out of 300 acne patients given a probiotic, 80 percent had clinical improvement. Read on to learn how you can naturally treat your cystic acne and have clear skin once again. What Is Cystic Acne? Also called nodulocystic acne and similar to nodular acne, cystic acne is an intense form of acne that results in large, inflamed cysts and nodules that appear on the skin. Unlike other milder forms of acne, cystic acne is noticeably painful and occurs when oil and dead skin cells build up deep down in hair follicles or pores. Cystic acne is most common during puberty for young boys, but sadly, it can continue into the adult years, especially when there is a hormonal imbalance. For adult women, it’s common to to experience cystic acne around their menstrual cycles, especially on the the jawline and chin, which are the common areas for hormonally motivated breakouts. It’s more serious than hormonal acne, which occurs with both men and women when undergoing significant hormonal changes, such as aging, pregnancy or stress. In contrast, cystic acne can happen at any age because of dietary sensitivities and an overproduction of sebum. Symptoms Acne vulgaris is the medical name for common acne. Acne conglobata, or cystic acne, is a more serious and rarer form of acne that occurs mainly in young men, but it can affect people of both sexes and various ages. When you have cystic acne, your skin’s pores get clogged with oil and dead skin cells and become inflamed. It becomes cystic acne when the pore ruptures underneath the skin, which causes the inflammation to spill out into the surrounding skin tissue. This chain reaction can continue in the skin, triggering wider inflammation, spreading more acne bacteria and more breakouts. Next, your body forms a cyst around the area to stop the inflammation from spreading further. Symptoms of cystic acne include: large, red and painful breakouts on the face, chest, back, upper arms, shoulders and/or thighs nodules that appear as raised, red bumps that generally do not have whiteheads showing — they can resemble a keloid lesions that are usually felt beneath the skin before they’re seen more visible acne that produces cysts and nodules in addition to papules and pustules breakouts that are painful to the touch or even when not touched decrease in self-esteem and mood and increase in psychological distress, especially when cystic acne occurs on the face The unique appearance of a cystic acne is due to the acute damage to the oil gland causing intense inflammation and irritation, which leads to redness, swelling and soreness. Cystic acne is easy to diagnose by a dermatologist and does not require any special tests. Causes Cystic acne can be caused by or related to: Genetics Hormonal changes, including polycystic ovary syndrome High levels of humidity and sweating Pore-clogging and irritating face and body care products Some drugs and chemicals (for example, corticosteroids, lithium, phenytoin, isoniazid), which may worsen or cause eruptions that are similar to acne Cystic acne often runs in families. If one or both of your parents had severe cystic acne, then you have a greater chance of having it as well. It’s most common in teenage boys and young men. It’s believed that hormones called androgens can play a part in the development of cystic acne in teens when there is an increase in androgens. This increase leads to changes in your skin that can result in clogged pores and acne. Cystic acne doesn’t only affect men, though. For women, hormone changes that trigger cystic acne can be brought on by menstrual cycles, pregnancy and menopause. Conventional Treatment Cystic acne is the most severe form of acne, but over-the-counter remedies aren’t always enough to treat this form of acne. If any, benzoyl peroxide is a topical antibacterial treatment that is most often used to treat acne and may help less severe cystic acne. Instead, many people opt to see a dermatologist in order to get diagnosed and then prescribed medications to treat cystic acne. The most effective conventional medicine for cystic acne is isotretinoin (Accutane), which actually is derived from vitamin A. While most people experience a reduction in acne lesion counts, adverse events are common, especially overly dry skin, mood issues and decreased appetite. If the cystic acne covers a lot of skin, a dermatologist may want to prescribe oral antibiotics. While these can work against the inflammation and bacteria, they don’t address the excess oil or dead skin cells. Because of antibiotic resistance, they should only be used in the short term, if at all. Topical retinoids also may be used and are related to vitamin A, but in general they’re not sufficient to address cystic acne. They can also make your skin red and peel — plus make it very vulnerable to sunburn. Another prescription medication is spironolactone (Aldactone), a diuretic that usually is used for edema as well as high blood pressure. It’s also used for acne but mostly just women who have acne around their jawline. Its side effects can be serious and should not be taken if planning to become pregnant. Natural Remedies 1. Avoid these foods Conventional Dairy: Even if you’re not lactose intolerant, conventional dairy products can be hard on the digestive system. Many people see an improvement in their acne when they cut down or eliminate dairy products like milk, cheese and ice cream. If you want to check if dairy is a culprit, try eliminating it from your diet for two weeks to see if your cystic acne improves. If it does, then you know that dairy is not agreeing with you. You can choose to remain dairy-free, or you can slowly reintroduce dairy back into your diet. Choosing better-quality dairy can be helpful as well. Sugar: Sugar and other high-glycemic foods (like breads and pasta) can make inflammation in your body worse. The more inflammation you have, the worse your cystic acne will be. Try natural sweeteners instead. Consuming excess amounts of sugar and grain products can also feed yeast and candida in the body, increasing the presence of acne on the skin. Caffeine and chocolate: Many experts like to say that there is no link between caffeine and chocolate consumption and breakouts. However, there is no doubt that caffeine consumption has a direct impact on your hormonal balance. In particular, caffeine overdose can raise the stress hormone known as cortisol, which can cause cortisol face. By reducing or eliminating various sources of caffeine, like coffee, tea and chocolate, you can help keep your hormones in better balance and clear up your cystic acne. Low-fiber, highly processed foods: Consuming foods that are low in fiber and highly processed has a direct negative effect on your gut health, which negatively impacts skin health. When you consume processed meat products like cold cuts, breakfast cereals and microwave meals, an unhealthy shift occurs in your inner microbial colonies. This sets off inflammation throughout your entire body, which can bring on a cystic acne flare-up or make any current acne even worse. Fried and fast foods: These foods are also highly processed and low in fiber. Additionally, they contain a number of ingredients that cause inflammation, including hydrogenated oils, sodium, chemicals, flavorings and sugar. 2. Eat these foods Probiotic-rich foods: The healthier your gut is, the better your balance of good versus bad bacteria. When you consume probiotic-rich foods like kefir and cultured vegetables, the probiotics line your gut and create a healthy, sealed barrier that prevents inflammation that can trigger acne. One Korean study of 56 acne patients found that drinking a Lactobacillus-fermented dairy beverage effectively reduced their total acne lesion count and decreased oil production over 12 weeks. High-zinc foods: People with acne tend to be low in zinc so you definitely want to increase your dietary intake of zinc by consuming things like grass-fed beef, chickpeas, pumpkin seeds and cashews to prevent a zinc deficiency. Zinc also supports a healthy digestive tract, which improves skin health. Vitamin A-rich foods: Foods high in vitamin A, like kale, spinach, sweet potatoes and carrots, fight infection and speed healing, two things you definitely need when you’re trying to get rid of cystic acne. Fiber-rich foods: Consuming high-fiber foods like vegetables, fruits, nuts, seeds and oatmeal encourages colon cleansing as well as the growth of good bacteria in the gut, both of which can help eliminate cystic acne. High-quality protein foods: Grass-fed beef, organic chicken, wild-caught fish and free-range eggs are high in protein and nutrients and help balance blood sugar, a key component in the fight against cystic acne. Liver-supportive foods: Since hormones are processed in the liver, eating liver-supportive foods can help clear up acne. Eat more cruciferous vegetables like broccoli and cauliflower as well as leafy greens and high-fiber fruits, such as pears and apple, for improved liver function. 3. Consider taking these supplements Probiotics (10,000 IU to 50,000 IU daily, typically two to three capsules twice daily) — Taking probiotics can boost your immunity and help your internal fight against cystic acne. You can also use probiotic skin care products, which can provide a protective external shield. Studies show that probiotics may help prevent skin eruptions. Omega-3 fatty acids (1,000 milligrams of fish oil/cod liver oil daily or 3,000 milligrams of flaxseed or chia seed oil) — Omega-3 helps reduce inflammation and support hormone balance. One scientific study specifically found that after 10 weeks of omega-3 fatty acid or GLA supplementation, inflammatory and non-inflammatory acne lesions decreased significantly. Zinc (25–30 milligrams twice daily) — Research suggests that people with acne have lower blood and skin levels of zinc. Taking zinc by mouth may help reduce acne. Vitex (160 milligrams of Vitex/chasteberry) — This herbal remedy is specifically recommended for hormonally induced acne. Guggul or guggulsterone (25 milligrams twice daily) — Guggul is made from the sap of a tree native to India. For individuals suffering from cystic acne, a controlled clinical trial found that guggul supplements outperformed 500 milligrams of tetracycline. It’s also been shown to be effective for nodulocystic acne, a similar form of acne that usually targets the face, chest and back. 4. Consider essential oils Essential oils like tea tree and lavender can help fight cystic acne. The best way to use essential oils for acne is to apply two to three drops topically to the area of concern. Tea tree and lavender essential oils are safe for neat (direct) application, but they can also be combined with a carrier oil such as jojoba or coconut oil if you have sensitive skin. A scientific review of the efficacy, tolerability and potential modes of action in regard to the treatment of acne with tea tree oil states that tea tree products reduce lesion numbers in patients with acne, have tolerability levels that are similar to other topical treatments, and have antimicrobial and anti-inflammatory activities that are associated with the treatment of acne. Avoid exposure to direct sunlight when treating acne with essential oils. The UV rays can make your skin more sensitive and may lead to skin irritations or redness. If using any of these essential oils causes skin irritation, discontinue use of that oil. Skin Care Tips 1. No popping Whatever you...

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Reduce Hot Flashes with THIS Dietary Intervention

AHA Publisher — Mon, 14 Nov 2022 07:15:19 +0000

News Staff via NaturalHealth365 – Menopause is a natural part of getting older, signaling the end of a woman’s menstrual cycle. It usually starts when a woman is in her 40’s or 50’s. Unfortunately, menopause can have several uncomfortable side effects, including hot flashes, sleep problems, low energy, and emotional symptoms. However, a recent study indicates that a simple dietary change may significantly reduce aggravating hot flashes. Could This Straightforward Dietary Change Ease Menopausal Hot Flashes? What if you could reduce hot flashes just by changing your diet? A recent study, led by Dr. Neal Barnard and published in Menopause: The Journal of the North American Menopause Society, sought to find out. The trial was the Women’s Study for the Alleviation of Vasomotor Symptoms. To assess the link between diet and hot flashes, researchers evaluated postmenopausal women over a 12-week trial period. Some study participants implemented a vegan diet low in fats and a half cup of soybeans daily, while the control group did not change their diets. All participants then recorded the severity and frequency of hot flash symptoms over the course of the study. The group that consumed a vegan, plant-based diet rich in soy experienced a whopping 88% reduction in their hot flashes. Also, those eating a plant-based diet lost an average of 8 pounds and reported improved quality of life. These results indicate that hot flashes can be reduced by simply cutting out toxic animal foods, lowering fat intake, and adding soy to the diet. Of course, we would encourage our readers to eat only non-GMO soy products. Hormone Replacement or Diet Changes? Hormone replacement therapy, or HRT, has long been the treatment of choice for perimenopause symptoms. This is because many symptoms of menopause stem from changes within the hypothalamic-pituitary-ovarian axis and disrupted hormone levels. However, HRT can cause its own set of unwanted side effects, if done incorrectly. The key here is to find a qualified healthcare provider to help you with the process to avoid health issues. If menopause symptoms can be mitigated through healthy diet changes, these dangerous side effects can be avoided. And besides possibly reducing hot flashes, plant-based diets have been shown to reduce depression and other chronic health issues. Thus, the new dietary study presents an exciting new direction for researchers to investigate further. Ways to Ease Menopause Symptoms Naturally Changing to a low (healthy) fat, plant-based diet and eating more soy might help reduce your hot flashes. But there are also other ways to ease menopause symptoms without pharmaceuticals. Black cohosh supplements, adequate sleep, regular exercise, and stress reduction practices like yoga can all help. There’s a possibility that plant phytoestrogens could improve menopause symptoms. Phytoestrogens are naturally occurring estrogens in several foods, including flax, soybeans, and legumes. Acupuncture and hypnosis are two more therapies that may benefit women in menopause. Menopause is an important and natural phase of life. However, if you’re dealing with uncomfortable menopause symptoms, it’s worth looking into dietary changes and complementary therapies to help ease the transition. Sources for this article include: Medicalnewstoday.com Mayoclinic.org Clinicaltrials.gov To read the original article click here.

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Environmental Toxicants Contribute to Obesity and Metabolic Disease

AHA Publisher — Wed, 09 Nov 2022 08:00:45 +0000

Bhavana Kunkalikar via News-Medical – In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders. Obesity results from higher energy intake compared to energy expenditure, which in turn results in an increase in adiposity. The calorie gap for preventing weight gain in various populations is only 8.2 to 61.2 kcal/day. A sedentary lifestyle and excessive energy consumption may not entirely account for the increasing prevalence of global obesity and accompanying metabolic diseases, despite the robustness with which energy balance is regulated. It’s interesting to note that many other species also seem to be developing obesity in addition to humans. These findings imply that other factors may also contribute to obesity, other than the increased availability of high-calorie foods and the decreased mobility caused by technology advancements. BAT and Thermogenesis and Prevention of Obesity The primary location for the accumulation of lipophilic environmental compounds is adipose tissue. BAT and white adipose tissue (WAT) are two different adipose tissue forms. Only eutherian mammals have BAT, which, unlike WAT, has a thermogenic function that gives animals an evolutionary advantage in the cold. Thermogenic activities performed by active BAT per gram of tissue oxidize plasma triglycerides and glucose at a relatively high rate. However, it should be noted that during exposure to cold, skeletal muscle-based thermogenesis contributes significantly more to energy expenditure because of its large bulk. Four weeks of acclimation to cold is sufficient for adults to increase BAT thermogenesis and decrease skeletal muscle shivering. This highlights the potential significance of BAT concerning whole-body energy expenditure. In contrast, inhibition of adipose tissue lipolysis decreases BAT thermogenesis and promotes muscle shivering. Studies suggest that uncoupling protein 1 (UCP1) and BAT also promote energy expenditure in humans, regardless of cold exposure by boosting diet-induced thermogenesis (DIT). DIT accounts for 5% to 15% of the daily energy expenditure, depending on the make-up and quantity of the food consumed. In addition, a study showed that consuming a meal rapidly increases blood flow and oxygen consumption in BAT. As a result, DIT thermogenesis might play a significant role in humans’ daily expenditure of energy when they are in thermoneutral environments. Therefore, inhibition of this process might be linked to obesity and metabolic disorders. The Pesticide Chlorpyrifos Inhibits Diet-Induced Thermogenesis in BAT The team screened brown adipocytes expressing the UCP1 promoter associated with luciferase to identify environmental contaminants that could directly decrease BAT function. A total of 34 widely used pesticides were screened, including food packaging substances, herbicides, and food colors that shared structural similarities with serotonin, a substance that inhibited BAT thermogenesis. The team noted that UCP1 promoter activity, and protein and messenger ribonucleic acid (mRNA) expression, dramatically reduced in the presence of chlorpyrifos (CPF) at dosages as low as 1 pM. CPF, an organophosphate insecticide, is frequently applied to various field crops and fruits to control pests. Following treatment with 1 pM CPF, BAT cells were subjected to unbiased RNA sequencing, which revealed that the low dose of CPF caused noticeable alterations in mitochondrial gene expression. Subsequent research revealed that these changes were linked to deficits in mitochondrial respiration. These results demonstrated that CPF suppressed UCP1 expression and thermogenesis in cultured BAT cells within the exposure window within which individuals may be exposed to CPF through the ingestion of fruits and vegetables. The team noted that high CPF doses, which block brain and plasma acetylcholinesterase activity and plasma butyrylcholinesterase, can induce obesity and glucose dysregulation via mechanisms that may involve changes to the gut flora or increase in caloric consumption. However, weight gain, glucose intolerance, insulin resistance, and non-alcoholic fatty liver disease (NAFLD) were also reported at the low CPF doses when test mice were maintained at thermoneutrality. This indicated that CPF levels consistent with non-occupational exposure in individuals might encourage obesity by preventing diet-induced thermogenesis in BAT. Other Environmental Pollutants Which May Inhibit BAT Function Numerous environmental toxins bind to hormone receptors, such as androgen receptors (ARs), aryl hydrocarbon receptors (AhR), estrogen receptors (ERs), estrogen receptor-related receptors (ERRs), thyroid receptors (TRs), and pregnane X receptors (PXR) interfered with hormonal effects. These receptors play a crucial role in controlling BAT thermogenesis. Environmental toxins include DDT, organochlorine, and vinclozolin block androgen receptor-mediated processes, including UCP1 transcription. Some environmental toxins may influence BAT thermogenesis by imitating estrogen’s actions. For instance, the most popular industrial chemical used in manufacturing plastics, bisphenol A (BPA), causes weight loss without altering caloric intake. In addition, maternal exposure to BPA at the time of pregnancy mimics a weak estrogen agonist, increasing interscapular BAT weight and upregulating UCP1 expression in female offspring but decreasing BAT activity and brown adipogenesis in male offspring. Overall, the study findings highlighted that specific environmental contaminants might inhibit BAT’s thermogenesis. Further research should be conducted at different doses in BAT cell lines in order to assess this possibility and provide translatability to humans more accurately. Journal reference: Bo Wang, Gregory R. Steinberg, Environmental toxicants, brown adipose tissue, and potential links to obesity and metabolic disease, Current Opinion in Pharmacology, Volume 67, 2022, 102314, ISSN 1471-4892, DOI: https://doi.org/10.1016/j.coph.2022.102314, https://www.sciencedirect.com/science/article/pii/S1471489222001412 To read the original article click here.

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Need Thyroid or Hormone Support? Take Our Quiz Today!

AHA Publisher — Mon, 07 Nov 2022 05:47:26 +0000

Dr. Don Colbert – A woman’s body is constantly changing. Every decade, every year, even within each month, women experience hormone ebbs and flows, and changing bodies. While this may seem unsettling, it doesn’t have to be. In fact, it can be a great opportunity to learn to nourish your body with thyroid and/or hormone support as needed. You may be at the point in your life where some extra nutrients are needed. Your body may no longer be in balance. Here are 12 signs you can benefit from thyroid or hormone support (1, 2, 3). Thyroid and Hormone Support Quiz Are any of the following true for you? You feel chronically fatigued, and you can’t explain why. You are increasingly sensitive to cold or heat. You cannot lose weight no matter what you try. You’ve suddenly lost weight and did not want to. You’re experiencing thinning hair including eyelashes and/or eyebrows. You’re experiencing unwanted hair growth (on face, etc). You’re experiencing newly on-set acne, especially along your jawline. Your muscles and joints feel increasingly stiff or painful. You are experiencing night sweats or sweating profusely during the day. You are experiencing newly-onset urinary incontinence. You are experiencing sleep disturbances; trouble falling asleep and/or staying asleep. You feel like you are constantly in a PMS state: feeling anxious, overwhelmed, irritable, crampy, bloated, etc. Why These Symptoms Are Important If you answered yes to at least 3 of these questions, you may benefit from all-natural thyroid and/or hormone support. Unfortunately, for decades or even centuries, most of these symptoms have simply been chaulked up to “aging” or menopause. While women certainly age and experience body changes, and go through menopause and experience body changes, we don’t have to experience many of the negative and uncomfortable symptoms that come with them. In fact, most of these issues are easily soothed with thyroid and hormone support. The right nutrients can actually reduce many negative symptoms, improve balance within your body, and support whole-body wellness. You don’t have to feel poorly year after year. You can feel great again! Here’s how. How Thyroid Zone Can Help Your thyroid affects almost all of your body systems. Many thyroid issues are due to an imbalance or inadequacy of minerals, many of which are difficult-to-obtain in the diet. How can you support your thyroid? Consider Keto Zone® Thyroid Zone. This supplement specifically supports your thyroid by providing a variety of minerals and nutrients that promote healthy thyroid function. These nutrients are important for whole-body health and may improve the symptoms of hypothyroidism. In fact, Keto Zone® Thyroid Zone contains natural iodine, selenium, zinc, copper, vitamins A, D, and B12, Ashwagandha extract, Guggul extract, Coleus Forskohlii, L-Tyrosine, Schizandra, Kelp, Bladderwrack, and Cayenne – important minerals and nutrients for thyroid health (4). Thyroid Zone has been designed to encourage: Optimal Thyroid Hormone Production T4 to T3 Conversion Thyroid Hormone Activation Balanced Iodine Levels Optimal Thyroid Enzymes And Function Protection of the Thyroid From Oxidative Stress Weight Loss Healthy Metabolism Balanced Energy Thyroid Zone promotes balance and health in your thyroid, and therefore, your entire body. How Hormone Zone Can Help In addition, Dr. Colbert has formulated a ground-breaking supplement that supports women’s hormones. Specifically, Keto Zone® Hormone Zone contains Diindolylmethane (DIM), Vitamin D3, and Vitamin K2. Together these nutrients support balanced hormones throughout a woman’s life while also promoting bone health, heart health, and whole-body health. Here’s a summary of each: DIINDOLYLMETHANE (DIM) FOR HORMONE SUPPORT Diindolylmethane (DIM) is an important compound produced by our bodies when we eat cruciferous vegetables. If you’ve ever heard the advice to eat more greens to lower breast cancer risk, it’s due to the resulting production of DIM. DIM alters the metabolism of estrogen in order to help our bodies balance hormones. How? First, it can block an enzyme that converts testosterone into estrogen. Next, DIM converts “bad estrogens” (there are many forms) into good estrogen metabolism. It’s the bad estrogen forms that cause most PMS (pre-mentrual syndrome) and menopause symptoms). Further, DIM encourages pathways that encourage good estrogen production. DIM is a powerful compound for balancing a woman’s hormones and reducing negative estrogen symptoms (5). VITAMIN D3 Vitamin D3 is a prohormone, or nutrient that is readily converted to its hormone form in the body. It is extremely important for a myriad of health functions, including calcium regulation, mental health, immune function, healthy bones and teeth, and metabolism. The vast majority of adults are low in vitamin D3. When it’s deficient, they may experience more infections and illness, lower bone density, cardiovascular disease, and mental illnesses and disorders like depression (6). Adding more Vitamin D3 supports women’s health! VITAMIN K2 Vitamin K2, or menaquinone, is found in animal foods and fermented foods. Most people have heard of vitamin K1 because it’s important for blood clotting, from birth onward. But the importance of vitamin K2 for bone health has only recently been discovered. What’s more, K2 is often deficient in adults. Vitamin K2 is extremely important for bone health, especially in post-menopausal women. Supplementing vitamin K2 and vitamin D together may reduce spinal fractures, hip fractures, and osteoporosis. Further, vitamin K2 supports good dental health from infancy into advanced age (7). Together, these powerful ingredients work to promote: Healthy hormone levels throughout adulthood Optimal estrogen ratios and testosterone levels Bone density and reduced risk of fractures Dental health Immune function Cardiovascular health Healthy skin Daily energy Healthy weight It’s never too late to focus on your hormone balance and health. A great step is to add a natural, hormone-balancing supplement which includes DIM, Vitamin D3, and Vitamin K2, such as Keto Zone® Hormone Zone. Can You Take Thyroid Zone & Hormone Zone Together? If you’re looking to support your thyroid health and encourage healthy hormone balance, you can certainly take Keto Zone® Thyroid Zone and Keto Zone® Hormone Zone at the same time! In fact, they work great together as their compounds synergistically support women’s health! Want Testosterone Support As Well? Of course, it may seem like we’re overlooking the men (or the testosterone needs of women). This article is about women’s thyroid and hormone health, after all. But, we’ve not forgotten testosterone. In fact, Dr. Colbert has also formulated a testosterone supplement that supports men’s health. Keto Zone® Testosterone Zone is men’s answer for healthy testosterone levels through every decade. It is formulated with all-natural, potent ingredients including Testofen, a powerful all-natural testosterone-supporting compound. And best of all, you can get all three products, Keto Zone® Thyroid Zone, Hormone Zone, and Testosterone Zone in a cost-effective, convenient combo pack: Dr. Colbert’s Hormone Health System! Bottom Line Many people benefit from all-natural thyroid and hormone support and supplementation. Is it time for you to try them? Are you experiencing negative health symptoms that could be soothed or alleviated? Dr. Colbert’s Keto Zone® Thyroid Zone and Keto Zone® Hormone Zone are great supplements with which to start. You can experience positive thyroid, hormone, whole-body health effects. In addition, try Dr. Colbert’s Hormone Health System to add testosterone to the mix! To read the original article click here.

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Sweet Spice Supports Hormone Health, Improves Digestion and More

AHA Publisher — Fri, 18 Feb 2022 08:00:21 +0000

Wendy Miller via NaturalHealth365 – Star anise is one of many spices that is easy to recognize by both sight and flavor. It also has several health benefits that set it apart from other herbs and spices. The systemic benefits it offers are widespread and can support various bodily systems. The fact that it offers one of the most recognizable and well-known flavors across the world is a delicious plus. Let’s take a look at some of the benefits star anise offers. Help guard against pathogenic invaders by adding this spice to your diet Star anise has been proven to protect against the big three. As an antibacterial, antiviral, and antifungal, star anise keeps bacteria, viruses, and fungi from overtaking the body and causing illness and disease. It has been used for centuries in medicines and herbal blends to eradicate the dangerous organisms that make their way into the body and break down our defenses. Star anise supports digestive health in multiple ways Star anise has been shown to promote better digestion. When the small fruits are eaten after a meal, the digestive system works more efficiently. Bloating is kept to a minimum and less gas is produced. There is also less cramping and discomfort. Star anise helps regulate the bacteria in the gut making it easier for nutrients to be absorbed and utilized by the body. Why should we strive to have a well-balanced gut flora? Because a balanced gut improves the body’s ability to get the most out of the foods you eat. An abundance of phytonutrients makes this spice a potent antioxidant The immune system uses inflammation to protect injured areas of the body from further damage. Star anise can be used in tonics or tea to aid in the reduction of inflammation and swelling that is associated with either injury or illness. The list of phytonutrients contained in star anise makes it a key antioxidant that protects cells and flushes toxins from the body. As a tea, it may support joints and muscles by reducing inflammation throughout the body. Unique chemical compound gives this sweet spice immune-boosting properties Star anise is one of the most powerful immune boosters in the world due to its incredibly high content of shikimic acid. With the amount of shikimic acid it contains and the high level of antioxidants, star anise is known for its ability to boost the immune system. When consumed in small amounts when you start to feel under the weather, it can provide your body with what it needs to work through the health crisis. Protect against seasonal and environmental threats one sip at a time Star anise can be consumed as a tea when you first start to experience scratchiness in your throat. Its anti-inflammatory properties may help reduce swelling and discomfort. Its wide array of medicinal properties can help boost the immune system, which is only one part of the benefit. Anise also helps strengthen and repair cells that may be damaged by bacteria or a virus. But wait, there’s more! See how star anise may support hormone health Star anise and many of its licorice counterparts have a significant impact on hormones in both men and women. For men, it is beneficial as an energizer as well as boosting libido. For women, the benefits are many. From smoothing out mood swings to supporting menstrual cycles, balancing the hormones can alleviate many cycle-related troubles such as headaches, hot flashes, cramps, and nausea. What’s the Bottom Line? Whether you choose to consume star anise as a tonic, tea, or in capsule form, the list of benefits is quite lengthy. The fact is, it is one of the few spices that can have a positive effect on almost every system in the body. Understanding how it works and what it can do will help you use this vital and very potent spice to its fullest advantage. Sources for this article include: NaturalPedia.com OrganicFacts.net Dupischai.com To read the original article click here.

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Sleep and Biological Rhythm Variables Linked to Severity of Depression, Anxiety During Pregnancy

AHA Publisher — Wed, 19 Jan 2022 08:00:54 +0000

McMaster University via News-Medical – A set of parameters including sleep and biological rhythm variables are closely associated with the severity of depressive and anxiety symptoms, starting in the third trimester of pregnancy to the third postpartum month, according to a new study. The three-month period before and after giving birth is a vulnerable time for women’s mental health. It is estimated that 15 to 18 per cent of women experience anxiety and seven to 13 per cent experience depression during this peripartum period. In addition, nearly 10 per cent of women experience clinical levels of comorbid anxiety and depression during this time. In the largest observational study to date investigating changes in sleep and biological rhythms during the peripartum period, researchers identified several variables that are linked to depression and anxiety. Most notably, changes in the circadian quotient (the strength of the circadian rhythms), the average amount of activity during nighttime rest, and the amount of fragmentation of nighttime rest were strongly linked to higher depressive and anxiety symptoms. “Our findings highlight the importance of stabilizing the internal biological clock during the peripartum period to maintain healthy mood and minimize anxiety,” said Benicio Frey, senior author of the study and professor in the department of psychiatry and behavioral neurosciences at McMaster University. “Given the findings, future efforts should be made to standardize evidence-based interventions targeting these biological rhythms variables identified by our team, either as treatment or prevention strategies.” Frey and his research team conducted the study from the Women’s Health Concerns Clinic at St. Joseph’s Healthcare Hamilton. This clinic specializes in psychiatric disorders during the peripartum, premenstrual, and perimenopausal periods. Researchers recruited 100 women, 73 of whom they followed from the start of the third trimester to three months postpartum. They analyzed subjective and objective measures of sleep, biological rhythms, melatonin levels, and light exposure using a variety of tools, including questionnaires, actigraphs (wearable sleep monitors), laboratory assays, and other methods. Interestingly, the findings indicate that certain biological rhythms variables may be important to depressive symptoms at specific points along the peripartum timeline. For instance, higher fragmentation of nighttime rest was linked to a decrease in depressive symptoms at six to 12 weeks postpartum – a period that tends to coincide with a higher risk of developing postpartum depression. To read the original article click here.

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Hormone Exposure in the Womb Potentially Linked to Migraine Risk in Later Life

AHA Publisher — Tue, 21 Dec 2021 08:00:28 +0000

Frontiers via Newswise – Hormone levels in the womb before birth have been potentially linked to the risk of developing migraine in adulthood, reveals a new study of genetic and environmental information from the world’s largest database of twins. The research is also the first to show that genetic factors related to migraine risk may be different for men and women. The researchers hope these findings will enable more effective and targeted treatment options for this debilitating disease. The risk of experiencing migraine in adulthood has been linked to factors in the womb, finds a new study published in Frontiers in Pain Research. It also found evidence to suggest that different genes influence migraine risk in men and women. “We are the first to show that females with a male co-twin have a higher risk of migraine compared to females with a female co-twin, suggesting that prenatal factors, possibly relating to in utero hormone levels, may contribute to migraine risk,” said Morgan Fitzgerald, lead author of the study, from the University of California, San Diego School of Medicine. “We are also the first to present evidence that genetic factors related to migraine risk may be different between females and males.” Debilitating Disease Migraine is a severe, debilitating neurological disease that affects more than 12% of the world’s population. Females are more likely to suffer from migraine by a factor of nearly seven to one, and it is a leading cause of disability in young women. “Despite its prevalence, the factors that contribute to migraine are poorly understood,” said Dr Matthew Panizzon, principal investigator of the study, also based at the UC San Diego School of Medicine. “With the data from the Swedish Twin Registry, the largest twin registry in the world, there was a unique opportunity to probe factors contributing to female-male differences in migraine.” The researchers examined data from 51,872 individuals who had participated in prior Swedish Twin Registry studies. They identified those who experienced migraine without aura based on criteria set by the International Headache Society Classification of Headache Disorders. “Since the data were collected from twins, we were able to use analytic methods that allowed us to test whether migraine risk was driven by different genes in females and males, and whether the presence of an opposite-sex twin in utero, which is believed to impact prenatal hormone levels, had an influence,” explained Fitzgerald. “We found that the prenatal environment may contribute to migraine risk, and that some of the genetic factors that contribute to migraine risk may be different between females and males.” Improved Treatment Options “The findings of our study are important because the more we understand the factors that contribute to migraine, and especially the differences between males and females, the more opportunity there is to improve clinical care, diagnostic abilities, and therapeutic interventions for both men and women,” added Panizzon. Further questions remain, such as what factors dictate the presence or absence of aura with migraine, and at what age and in what stage of life does migraine begin. “Unfortunately, age at onset was not available in the Swedish Twin Registry data. In fact, most studies do not ask individuals when their migraine attacks first start,” explained Fitzgerald. “In the future, we hope to examine how age at migraine onset coincides with the timing of critical hormonal events like puberty.” To read the original article click here.

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