hormone Archives - Amazing Health Advances

Magnolia Bark Benefits the Body, Mind & More

The AHA! Team — Mon, 08 Sep 2025 05:14:51 +0000

Joe Boland via Dr. Axe – Magnolia bark has been used for centuries in Traditional Chinese Medicine, but it’s now gaining attention in the wellness world for its natural calming properties, hormone-balancing effects, and potential role in supporting sleep, digestion and more. Derived from the bark of the Magnolia officinalis tree, this herbal remedy contains powerful plant compounds that may support both physical and mental health. Whether you’re dealing with stress, insomnia, inflammation or looking to support healthy aging, magnolia bark extract could be a helpful addition to your routine. So read on to explore what magnolia bark is, its top benefits, how to use it, potential side effects and common questions. What is magnolia bark? Magnolia bark comes from the Magnolia officinalis tree, a plant native to China and parts of Southeast Asia. The bark of the tree has long been used in Traditional Chinese Medicine (TCM) under the name Houpo, often in formulas for anxiety, digestion and respiratory issues. The main active compounds in magnolia bark are honokiol and magnolol, two polyphenols that give this extract its anti-inflammatory, antioxidant, neuroprotective and anxiolytic (anti-anxiety) effects. It’s also one of the main Chinese herbs for health. You’ll find magnolia bark extract in a variety of natural supplements aimed at stress relief, sleep support, hormone balance and cognitive performance. Magnolia bark benefits The benefits of magnolia bark are supported by both traditional use and growing scientific research. Here are some of the top health benefits of magnolia bark: 1. Promotes relaxation and reduces stress Magnolia bark is perhaps best known for its calming effects. Honokiol and magnolol interact with GABA receptors in the brain, similar to how anti-anxiety medications work, without the same risk of dependence. This makes it a popular natural option for managing stress and anxiety. A randomized, controlled trial published in the Journal of the International Society of Sports Nutrition found that participants who took a supplement containing magnolia bark extract and phellodendron experienced significant reductions in cortisol levels and improved mood after just four weeks. 2. Supports better sleep Because of its GABA-enhancing effects, magnolia bark is also used as a natural sleep aid. It may help you fall asleep faster and experience more restful sleep without grogginess the next day. In a randomized, controlled trial involving 143 postpartum women, researchers assessed the effects of drinking pure magnolia tea over a three‑week period. Compared to a control group, those consuming magnolia tea reported a significant improvement in sleep quality related to physical symptoms at the three‑week mark, and these benefits were still evident at six weeks post‑test. The study concluded that magnolia tea significantly alleviated sleep deprivation related to physical discomfort in postpartum women Some supplements combine it with melatonin or L-theanine for enhanced effects. 3. May aid weight maintenance and cortisol balance Chronic stress and elevated cortisol are linked to abdominal fat gain and weight retention. Magnolia bark’s ability to lower cortisol may support healthy metabolism and weight loss, especially when combined with healthy lifestyle habits. A 2006 randomized, double‑blind, placebo‑controlled trial examined overweight, pre‑menopausal women aged 20-50 who identified as “stress eaters.” The subjects took 250-milligram capsules three times daily (total milligrams per day) of a proprietary magnolia/phellodendron extract or placebo for six weeks. While the placebo group gained an average of about 1.5 kilograms over the study period, the treatment group participants maintained their weight, with 75 percent of placebo participants gaining at least one kilogram versus only 37 percent in the treatment group. As for cortisol, the study observed a trend toward lower evening salivary cortisol levels in the treatment group compared to the placebo group. While this did not reach conventional statistical significance, it suggests potential evening cortisol reduction associated with the extract. The proposed mechanism was that reduced cortisol may mitigate stress‑induced overeating, contributing to weight stability in those prone to stress eating. 4. Helps balance hormones Preliminary studies have suggested magnolia bark may help balance estrogen and progesterone levels, making it useful for managing symptoms of PMS, menopause and perimenopause, including mood swings and irritability. In a randomized, multicenter, controlled clinical study of 634 menopausal women (mean age of 53 years), researchers compared daily oral supplementation of “Estromineral Serena” (which included 60 milligrams of magnolia bark extract, along with isoflavones, lactobacilli, calcium, vitamin D3 and magnesium) against a control formula lacking the magnolia extract, over 12 weeks. Both groups experienced relief from classic vasomotor symptoms like hot flashes and night sweats. However, the group receiving magnolia‑enriched ES showed greater improvements in insomnia, irritability, anxiety, depressed mood, asthenia and loss of libido, symptoms closely tied to hormonal imbalance during peri‑ and post‑menopause. Importantly, well‑being scores and physician‑rated efficacy were significantly higher in the magnolia group (around 70  percent positive) versus the control (about 17  percent). 5. Offers neuroprotective and cognitive support Research has revealed that honokiol and magnolol can protect the brain from oxidative stress and inflammation, potentially reducing risk of neurodegenerative diseases. 2013 cell culture study A 2013 cell culture study examined how magnolol and honokiol (the major polyphenols in Magnolia officinalis bark) affected oxidative stress and inflammation in both neurons and microglial cells. The researchers found that both compounds inhibited NMDA-induced superoxide production in neurons, and in microglial cells they suppressed NADPH oxidase activation, iNOS expression, and production of ROS and nitric oxide via dampening the ERK1/2 signaling pathway. These findings indicate that magnolol and honokiol can attenuate excitotoxicity, reduce oxidative stress and mitigate neuroinflammation in vitro, mechanisms closely linked to neurodegeneration and cognitive decline. Animal studies also have suggested it may support memory and cognitive performance. 6. Provides antioxidant and anti-inflammatory effects Magnolia bark extract is rich in polyphenols, which help fight free radical damage and reduce chronic inflammation. Those are two major contributors to aging and chronic disease. 7. Supports digestive and respiratory health Traditionally, magnolia bark has been used to relieve bloating, gas, nausea and even coughing. Its anti-inflammatory properties may help reduce gut inflammation and support a balanced microbiome. 8. Holds potential anti-cancer properties Emerging research has revealed that compounds in magnolia bark, especially honokiol, may help inhibit the growth and spread of certain cancer cells. Honokiol has demonstrated pro-apoptotic effects, meaning it can trigger the natural death of damaged or cancerous cells, particularly in the breast, lung and colon. While most studies are in early stages or preclinical models, they show promising results for future integrative therapies. 9. May help lower blood sugar Animal studies have indicated that magnolia bark extract may support healthy blood sugar levels by improving insulin sensitivity and reducing glucose levels. This makes it a potentially useful herbal ally for people managing metabolic syndrome or at risk of type 2 diabetes, though more human trials are needed to confirm these effects. 10. Holds antimicrobial and antibacterial powers Magnolia bark has shown broad antimicrobial activity against several types of bacteria, including those involved in oral health issues such as gingivitis and bad breath. Its antibacterial compounds may help inhibit the growth of harmful pathogens in the gut and respiratory tract, contributing to overall immune health. In a randomized, controlled intervention trial involving nine healthy adult volunteers, participants consumed sugar‑free chewing gum and compressed mints containing magnolia bark extract (MBE) following lunch. Saliva samples were collected before and at intervals after consumption. The results showed that the products containing magnolia bark reduced total salivary bacteria by approximately 62 percent at 30 minutes and 43 percent at 40 minutes, whereas the placebo chewing gum or mint showed minimal effect or even an increase in bacterial counts. Notably, MBE components (magnolol and honokiol) demonstrated strong inhibition of key oral bacteria, such as Streptococcus mutans, Porphyromonas gingivalis and Fusobacterium nucleatum. How to use Magnolia bark is available in several forms, including: Capsules or tablets Powdered extract Tinctures or liquid drops Herbal teas (less common) Suggested dosage: A typical dosage of magnolia bark extract ranges from 200 to 500 milligrams per day, often split into two doses. Some formulations may combine magnolia bark with other calming herbs, so be sure to check the label. Best time to take: For sleep support, take it about 30-60 minutes before bed. For anxiety or cortisol management, doses may be taken in the morning or afternoon. Always follow the instructions on the supplement label or speak with a healthcare provider to determine the best dosage for your needs. Risks and side effects Magnolia bark is generally well-tolerated, but like any supplement, it’s not without risks. Potential side effects may include: Drowsiness or sedation, especially if combined with other sedatives or alcohol Headache or dizziness in some individuals Gastrointestinal upset, such as nausea or diarrhea (rare) Who should avoid it? Pregnant or breastfeeding women should avoid magnolia bark due to limited safety research. People taking sedatives, anti-anxiety medications or sleep aids should consult a doctor to avoid additive effects. If you have a hormone-sensitive condition (such as breast cancer), speak with your doctor first, as magnolia bark may interact with estrogen pathways. Frequently asked questions What does magnolia bark do to the body? Magnolia bark promotes relaxation, helps manage stress and anxiety, supports hormonal balance, and may protect the brain and body from oxidative stress and inflammation. Is magnolia bark safe to take daily? Yes, magnolia bark is generally safe for short- to medium-term use. However, long-term safety has not been fully established, so it’s best to use it under the guidance of a healthcare professional. Does magnolia bark make you sleepy? It may have a mild sedative effect, especially in higher doses or when taken before bed. It interacts with GABA receptors, which help calm the nervous system and may promote sleep. Can magnolia bark help with anxiety or depression? Yes, magnolia bark has been shown to help reduce anxiety symptoms and may support mood. It works similarly to some anti-anxiety medications by influencing neurotransmitters like GABA and serotonin, though more human studies are needed. Is magnolia bark extract the same as magnolia bark? Magnolia bark extract is a concentrated form of magnolia bark, often standardized to contain specific amounts of honokiol or magnolol. It’s more potent and commonly used in supplements. Who should not take magnolia bark? Magnolia bark should be avoided by pregnant and breastfeeding women and anyone taking sedatives, anti-anxiety drugs or sleep aids without first consulting a healthcare provider. Individuals with hormone-sensitive conditions, such as certain cancers, should also speak with a doctor before use due to magnolia bark’s potential interaction with estrogen pathways. Does magnolia bark increase testosterone? Magnolia bark is not typically used to boost testosterone directly. However, by helping to lower cortisol, which can suppress testosterone production, it may indirectly support healthy testosterone balance, especially in men under chronic stress. Does magnolia bark reduce cortisol? Yes, magnolia bark has been shown to help lower cortisol levels, particularly when used in supplement formulas targeting stress and anxiety. Lower cortisol can lead to improved mood, reduced belly fat and better hormone balance. What is the best way to take magnolia bark? The best way to take magnolia bark is in the form of a standardized extract in capsule or tincture form. Capsules with 200-500 milligrams of extract are commonly used for stress relief, while liquid tinctures offer faster absorption. Always follow dosage instructions on the label, and consider taking it with food to minimize any digestive discomfort. Conclusion Magnolia bark is a powerful natural remedy with a long history of use and promising modern research to back it up. From reducing anxiety and promoting sleep to supporting hormone balance, brain function and inflammation control, its benefits are broad and impactful. As with any supplement, it’s best to talk to a healthcare professional before starting magnolia bark extract, especially if you’re on medication or have existing health conditions. When used correctly, it can be a safe and effective way to help your body adapt to stress, rest better and feel more balanced. To read the original article click here.

The post Magnolia Bark Benefits the Body, Mind & More appeared first on Amazing Health Advances.

Oxytocin (The Love Hormone): Benefits + How to Increase Levels

The AHA! Team — Wed, 19 Feb 2025 06:11:36 +0000

Jillian Levy, CHHC via Dr. Axe – Why is oxytocin called “the love drug”? It’s responsible for many aspects of social bonding and sexual pleasure and affects emotions. Oxytocin, nicknamed by some experts “the tend and befriend hormone,” is one of the most important hormones that humans (and many other mammals) produce. It plays an important role in: social bonding building relationships reproduction childbirth breastfeeding raising children Here’s something that may come as a surprise: According to the American Psychological Association, oxytocin is released in response to both positive social connection and stressful conditions. Levels have been found to be higher when someone is under stress, such as when exposed to social isolation or when in an unhappy relationship. It’s thought that increased levels may help motivate people to reach out for help. On the other hand, situations that make us feel safe, happy and connected tend to cause the release of several “feel-good hormones,” including oxytocin, dopamine and serotonin. What is oxytocin? Oxytocin is a hormone (technically a peptide or neuropeptide) that is involved in bonding. As a neuropeptide, it’s a “chemical messenger” that acts on organs, including the brain. What does oxytocin do, and where is it produced? Oxytocin is produced in the hypothalamus region in the brain, often called the “control center” of the brain. It’s also thought to be influenced by activation of the amygdala, which is the region of the brain mostly associated with fear and memories. Once the hypothalamus sends signals for oxytocin to be produced, it’s either released into the bloodstream or to other parts of the brain and spinal cord. It binds to oxytocin receptors, influencing how we feel and behave toward others. Oxytocin influences the autonomic nervous system and the immune system. This includes having an effect on the “hypothalamic-pituitary-adrenal axis” (also called the HPA axis), which dictates release of many hormones. This peptide hormone has been said to have “broad implications” for general health, including facilitating adaptation to stressors, development, growth, healing, reproduction and social behavior. It also seems to have anti-inflammatory and even antioxidant effects, since it defends the body against trauma, illness and stress-induced damage. Additionally, it helps keep blood pressure levels in the normal range and also balances cortisol levels, a primary “stress hormone.” We usually think of it as a feminine hormone, but do men produce oxytocin too? Yes. While it was originally considered a hormone that was only found in women due to its tie to labor, lactation and raising children, it’s now known to be present and important in both men and women (although women are still thought to produce more). For example, oxytocin helps with male reproduction, as well as female reproduction, by supporting production of testosterone in the testes and motility of sperm. Additionally, it affects both sexes’ metabolisms, moods, immune systems and more. How the love hormone affects emotions Why is oxytocin called “the love drug”? It’s responsible for many aspects of social bonding and sexual pleasure and affects emotions. Oxytocin also has similarities to endorphins (opiate chemicals) because we produce more in order to soothe ourselves in response to sources of pain and stress. How does oxytocin make you feel? Here’s a basic overview of the emotional effects of oxytocin: Research has told us that oxytocin’s effects are basically the opposite of those linked to our “fight or flight” response. Higher levels are linked to feeling calmer and having a better capacity to deal with stress. Newer research has suggested that increased oxytocin can potentially also increase feelings of generosity, forgiveness, trustworthiness, joy and security. It seems to help increase fidelity and monogamy in relationships by keeping us honest and facilitating compassion/empathy toward others. Plus it increases feelings of protectiveness. Benefits/uses 1. Helps with social bonding and building relationships Can oxytocin make you fall in love? The release of oxytocin is associated with feelings of love and protection, as well as empathy, trust and connectedness. Studies have shown that oxytocin enforces pro-social behaviors, attachment, bonding and even fidelity by rewarding those who maintain good relationships with positive, calm feelings of well-being. One study demonstrated that people in the early stages of romantic attachment, within the first six months of a new relationship, had higher circulating levels of oxytocin. It’s also known that oxytocin levels are high during sexual activity and after orgasms. Many forms of social contact seem to result in bursts of oxytocin, even if it’s anticipated social contact, such as planning for a date, party or get-together. The hormone also works on a “positive feedback loop.” It makes us want to socialize, which further increases our oxytocin production, which then makes us feel good so we continue to seek out relationships with others. 2. Boosts ability to cope with stress While it also works under times of low stress, oxytocin has been shown to be elevated under times of high stress, too. Some studies have found that people who report having poor social relationships usually have higher circulating levels of both oxytocin and the stress hormone cortisol than those reporting better relationships. Externally administering the hormone via supplements has been shown to help mitigate stress reactions, acting as a type of natural buffer. It can make people who are stressed seek out support through better social connections. It may also help protect the nervous system from shutting down in the face of stressful circumstances, including childbirth. By increasing someone’s motivation to find help from others, the hormone can help people find opportunities and engage in behaviors that lead to more security, joy and love. 3. Induces labor What does oxytocin do in women to facilitate reproduction? Not only does it help women bond with their sexual partners or potentially the future fathers of their children, but oxytocin also strengthens labor contractions during childbirth, along with helping control bleeding after childbirth. It facilitates production of prostaglandins, which are chemicals that move labor along by increasing contractions. In prescription/synthetic form, it can be used to induce labor or speed up the process. The most widely used form is the brand-name drug Pitocin, which is commonly given to women in the hospital during labor. 4. Supports breastfeeding and child rearing According to a 2018 study focused on human evolution, some of oxytocin’s main functions are to support breastfeeding and nurturing maternal behaviors among both mothers and fathers. Research has linked the hormone to a mother’s ability to care for her infant in multiple ways, one of which is through breastfeeding. When a baby nurses from his/her mother’s breast, nerves in the nipple send a signal to the pituitary gland to produce oxytocin, which then causes tiny muscles around the nipple to squeeze and release milk. Experts also believe that oxytocin helps new mothers and fathers feel calm even during difficult life transitions, one of which is having and caring for a new baby. Levels have been shown to rise in parents due to affectionate touch and contact with their babies and children. 5. May have anti-aging and anti-obesity effects In one study, it was shown that higher oxytocin release is linked with protection against accelerated signs of aging and better regeneration of aged tissue stem cells, including muscle cells. Oxytocin injections may be used in the future to help injuries heal better, improve bone health and possibly prevent obesity. For example, some animal studies have found that oxytocin administration leads to sustained weight reduction by reducing food intake, which is believed to happen because it dampens the brain’s food-related reward circuitry. Additionally, it seems to reduce muscle and joint pain due to pain-dulling and anti-inflammatory effects. Higher circulating levels are also thought to be positively associated with lean mass and bone mineral density. 6. May help with social disorders Oxytocin has been investigated for its potential therapeutic effects on various psychiatric conditions characterized by social deficits and anxiety, including social phobia, autism spectrum disorders and postpartum depression. Research has suggested that oxytocin may modulate social behaviors and reduce anxiety, making it a promising candidate for treating social phobia. A review of clinical trials indicated that oxytocin administration could have beneficial effects across several conditions, including social anxiety. Oxytocin’s role in enhancing social cognition has led to studies exploring its application in autism as well. A meta-analysis of clinical trials found that oxytocin administration showed a significant combined effect in improving social behaviors in individuals with autism. The involvement of oxytocin in mood regulation and maternal behaviors has prompted investigations into its potential therapeutic effects on postpartum depression. Oxytocin is considered a promising neuromodulator for psychotherapeutic interventions in various psychiatric illnesses, including postpartum depression. While these findings are encouraging, it’s important to note that research is ongoing, and the therapeutic use of oxytocin for these conditions is still under investigation. Further studies are needed to fully understand its efficacy and safety profiles in these contexts. How to increase it Both higher- and lower-than-normal levels of oxytocin can cause health problems and changes in behavior among women and men, according to endocrinologists. Here are some examples of how: High levels among men may contribute to enlargement of the prostate gland (benign prostatic hyperplasia) and urinary problems. Low levels (what some might call “oxytocin deficiency”) among women can interfere with child labor and breastfeeding. Low levels among both sexes have been linked to depression and anxiety, although it still isn’t totally clear how administering oxytocin supplements can help treat these and other mental health conditions. It’s also believed that low levels may be tied to autism and autistic spectrum disorders. Wondering, “How can I increase my oxytocin levels?” Is there a supplement for oxytocin or foods that can naturally boost production? Here are ways that you can naturally boost your production in order to promote feelings of well-being and connectedness: Physical contact. Hugs, massages, being intimate, shaking hands and breastfeeding all cause the release of oxytocin. Physical contact can increase levels whether it’s between lovers, friends, or children and their parents. Essential oils. Research has shown that certain essential oils, including clary sage oil, may help balance hormones and encourage production of “the love hormone.” Making eye contact Laughing Giving and receiving gifts (including money) Altruistic behaviors, such as cooking for others and sharing meals together Petting a dog, cat or other pet Doing “loving kindness” meditations or visualization Telling someone you love him or her Listening to calming music Speaking to someone you trust on the phone Walking or exercising with someone Looking at photos or videos of people you care about, including via social media Supplements, sprays and dosage What happens if you take oxytocin in supplement or spray form? Although more research is still needed to confirm how oxytocin supplements and sprays affect our behaviors and moods, researchers think there’s a possibility that administering this hormone may help people dealing with social and emotional problems. Conditions that oxytocin may be able to help include: autism or Asperger’s disorder social anxiety schizophrenia depression Some early experiments have suggested that oxytocin nasal sprays or injections may help people with these conditions better identify emotional content and facilitate social information processing. The synthetic version of oxytocin given intravenously (Pitocin) is also used to induce labor. Can oxytocin be taken orally? At this time there isn’t an oral supplement of this hormone available. Because it’s destroyed in the gastrointestinal tract, it’s given by injection or nasal spray instead. Dosage of oxytocin depends on why it’s being given and someone’s response; therefore it must be individualized. When it’s given to induce labor, IV infusion is used along with frequent monitoring. Infusion doses starting at 0.5 to 1 milliunits/minute, in some cases increasing up to 6 milliunits/minute, are typically given to women during labor. Does food have oxytocin? This hormone is not found in foods, but it does play a role in regulating appetite. Eating aphrodisiac foods (such as chocolate, coffee, fish, avocado and some herbs) may also improve your mood and desire for connection, leading to higher release. Risks and side effects Are there any oxytocin supplement...

The post Oxytocin (The Love Hormone): Benefits + How to Increase Levels appeared first on Amazing Health Advances.

Study Reveals Higher Breast Cancer Mortality Risk for Black Women Across All Tumor Types

The AHA! Team — Fri, 25 Oct 2024 08:15:48 +0000

Mass General Brigham via News-Medical – Breast cancer is the most diagnosed cancer among U.S. women and the second leading cause of cancer death. Black women who develop breast cancer are around 40% more likely to die of the disease than white women, but it was unclear until now whether this disparity exists across all types of breast cancer. Now, a meta-analysis led by Mass General Brigham researchers shows that Black women have a higher risk of dying from breast cancer for all tumor subtypes, and the size of this disparity varies from 17-50% depending on the type of breast cancer. These findings, published in the Journal of Clinical Oncology, demonstrate that higher mortality rates among Black women with breast cancer are at least partially attributable to factors that are independent of tumor biology-;for example, socioeconomic inequality, delays in diagnosis, and inadequate access to timely quality cancer treatment resulting from systemic racism. “Our findings demonstrate that multiple, interacting factors contribute to disparities in breast cancer survival between Black and white women. To achieve equity, intervention is necessary at multiple levels-;from community to healthcare systems and individual healthcare providers, to patients themselves learning about their disease and what their expectations should be for their care.” Erica Warner, ScD, MPH, senior author, cancer epidemiologist at Massachusetts General Hospital, founding member of the Mass General Brigham healthcare system Though it is often discussed as a single disease, breast cancer has multiple subtypes that differ in risk factors, treatment, and prognosis. These subtypes are defined based on whether the cancer cells carry hormone receptors for estrogen or progesterone, which can be targeted for treatment, and whether they carry HER2 (human epidermal growth receptor 2), a protein associated with cancer aggressiveness and another potential treatment target. Breast cancer has multiple subtypes that differ in risk factors, treatment, and prognosis “There had been an anecdotal sense in the research community that differences in survival between Black and white women were greater for the most treatable forms of the disease-;tumors that carry hormone receptors-;and smaller for the historically less-treatable, hormone-negative tumors,” said Warner. To investigate whether these anecdotes were supported by the evidence, Warner’s team combined data from 18 studies that were published between 2009 and 2022. Altogether, these studies analyzed 228,885 breast cancer cases, 34,262 of which were in Black women. They found that survival was worse for Black women for all breast cancer subtypes, though the size of these disparities varied between breast cancer subtypes. There was a larger racial disparity for hormone-positive tumors, which were associated with a 34-50% higher risk of death for Black women, compared to hormone-negative tumors, which were associated with a 17-20% higher risk of death for Black women. “These findings underscore a stark reality in our healthcare system: Black women are facing higher risks of death from breast cancer compared to their white counterparts, across all types of the disease. This disparity isn’t just about biology,” said co-author Paulette Chandler, MD, MPH, associate epidemiologist in the Division of Preventive Medicine at Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system. “It’s a call to action for healthcare providers, policymakers, and communities alike to confront these inequities head-on and strive for meaningful change in breast cancer outcomes.” Because hormone-negative tumors are less common, Warner says that racial disparities in breast cancer survival for hormone-negative subtypes were likely not observed previously because individual studies lacked statistical power due to the small number of cases. “There may also be differences in the biological characteristics of some tumor subtypes between racial groups that our therapies are not attuned to, potentially because of underrepresentation of Black women in clinical trials,” said Warner. The researchers point to several existing multilevel intervention programs However, these racial disparities are not inevitable, and the researchers point to several existing multilevel intervention programs that have successfully reduced disparities in cancer survival. These programs leverage multiple strategies, including helping patients navigate the healthcare system, proactively identifying social needs and connecting patients with resources to address those needs, and by implementing systems that alert healthcare workers of missed appointments or unmet care milestones. At the national level, interventions like ACCURE and Equal Hope aim to close gaps in mortality and survival between Black and white women. Locally, MGH is collaborating with Boston Medical Center on a virtual Equity Hub for Cancer Treatment with the goal of enhancing partnerships and improving cancer care for underserved patients at community-based mental health centers. Source: Mass General Brigham Journal reference: Torres, J. M., et al. (2024) Racial Differences in Breast Cancer Survival Between Black and White Women According to Tumor Subtype: A Systematic Review and Meta-Analysis. Journal of Clinical Oncology. doi.org/10.1200/JCO.23.02311. To read the original article click here.

The post Study Reveals Higher Breast Cancer Mortality Risk for Black Women Across All Tumor Types appeared first on Amazing Health Advances.

How Fiber Can Improve Your Mental and Brain Health + Tips on Boosting Gut Health and Overcoming Food Sensitivities with GI Specialist Dr. Will Bulsiewicz

AHA Publisher — Mon, 18 May 2020 07:00:30 +0000

Dr. Caroline Leaf – We all know fiber is good for us, but did you also know that it can help with your mental health? In this week’s blog and podcast, I spoke with GI specialist and epidemiologist Dr. Will Bulsiewicz about how a high-fiber diet can help boost mental and brain health, heal food sensitivities and reduce inflammation in the brain and body! In his amazing new book, Fiber Fueled: The Plant-Based Gut Health Program for Losing Weight, Restoring Your Health, and Optimizing Your Microbiome, Dr. B notes how even though he was very successful as a medical doctor, his processed food diet was making him miserable, tired and anxious. When he met his wife, he began to understand how real, healthy whole foods could transform his life, which led him on the path he is on today: meeting people where they are in their journey and helping them live their best and healthiest lives. As Dr. B points out, although the current healthcare system is really good at treating acute diseases, it falls short when it comes to preventative medicine and chronic health issues. Indeed, as a medical doctor with multiple qualifications, Dr. B was taught little about the impact lifestyle choices such as diet and exercise could impact our mental and physical health—he had to learn that from his wife! Thankfully, times are changing, especially as more and more research is being published on the importance of our lifestyle choices. We now know that pills and procedures are not everything; around 20% of diseases are genetic, which means 80% are related to our diet and lifestyle. This is great news! It means that our health is largely in our hands, which very empowering. In fact, we are just beginning to understand the importance of the gut-brain connection and diet on our mental and physical health. 15 years ago, we largely dismissed the role of our gut, but now we know that it is integral to our mental and physical health. As I discussed in a recent blog and podcast (episode #156), the gut is your brain’s best friend. They are constantly talking to each other like teenagers! There are 500 million nerve cells in the gut (5 x more than the spinal cord!), which send signals through vagus nerve to the brain, affecting our sympathetic and para-sympathetic nervous systems, hormones and the rest of your brain and body. Indeed, 90% of the neurotransmitter serotonin is produced in the gut, which not only regulates our mood, energy levels and focus, but also impacts our motility, that is our ability to digest, absorb and eliminate food products. When you damage the microbiome, you damage serotonin production, which affects and mood, which then impacts the rest of brain and body! One of the best ways we can ensure that our gut microbiome is happy and healthy is what Dr. B calls the production of postbiotics. We have all heard of probiotics (good bacteria) and prebiotics (the fiber that feeds the good bacteria in the gut). The magic happens when these two come together to form postbiotics which are necessary for a great digestive system, such as short chain fatty acids. These postbiotics not only heal things like leaky gut, but they also help with “leaky brains”, repairing the blood-brain barrier and helping us think clearly and quickly and boosts our mood, while helping protect us against the onset of cognitive decline. We get these postbiotics by eating a healthy, plant-rich diet, which is high in fiber that exercises the gut, feeding the good bacteria we need for digestion and keeping us happy and healthy! In fact, a high fiber diet can even reduce the inflammation associated with cardiovascular disease. When we eat a wide diversity of plants from fruits, veggies, nuts, seeds, grains and so on, we are supporting a wide diversity of good bacteria in our gut—every plant has a unique mix of fiber that feeds a unique mix of bacteria. This way of eating helps us live long and healthy lives, just like the people in what is known as the blue zones—areas of the world where there is the highest life expectancy, which I talked about in a recent blog and podcast (episode #149). A high fiber, plant-rich diet can also help with food sensitivities. As humans, we only have 17 digestive enzymes, so we need some digestive help from the good bacteria in our stomach. If, however, our microbiome is damaged or unhealthy, we can develop food sensitivities, especially if we are eating a highly processed and refined Modern American diet, known as MAD, that is so common today (I discuss this in detail in my book Think and Eat Yourself Smart). If we eat a diet rich in plant fibers, we can start to heal the gut microbiome, feeding the good bacteria that helps break down our food. However, like many things in life, this is a process and takes time, so learn to listen to your body and give yourself grace! Start small and where you are, and realize that the healing process may involve some pain and discomfort. Like training your body at the gym, you are training your gut to be healthy and strong again! There Are Also Other Non-Diet Related Ways We Can Boost Our Gut Health and Heal Our Microbiome 1. Get more sleep! A good night’s rest helps heal and repair the brain and the gut, so make sure you are catching those z’s! You can do this by avoiding blue light exposure before bed (for more on this see my blog and podcast episode #114). If you are battling to fall asleep at night, you can also try eat dinner earlier and water fast before bed. For more on sleep, see my blog and podcast episode #97. 2. Exercise. Exercise does wonders for our mental and physical health, and can really help boost our gut health and aid digestion! For more on the benefits of exercise, see my recent blog and podcast episode #139. 3. Practice mind management. As I have mentioned many times before, we need to manage our mind, which plays a massive role in our gut health! Toxic stress and chaotic, uncontrolled thinking both directly and indirectly impact the balance in our gut (as discussed above), so we should take the time to control our thinking through practices like yoga, meditation and mindfulness. My SWITCH app is a great tool for helping you learn how to manage your mind, deal with the root of your stress and anxiety, and overcome negative thought patterns and behaviors that impact gut health through the mental process of reconceptualization. It is now on sale less 50% for a 3-month subscription! I also recommend taking a lot of “thinker moments” throughout the day, where you switch off to the external and just let your mind wander and daydream. These moments give your brain a rest and allow it to reboot and heal, which increases your clarity of mind and ability to problem-solve when faced with a tough situation. So, be intentional about creating “thinker” breaks throughout your day by taking a few moments every day, or when you are feeling stressed out! For more information on thinker moments and how to make them a part of your daily routine, see my book, Think, Learn, Succeed. To read the original article click here. For more articles from Dr. Leaf click here.

The post How Fiber Can Improve Your Mental and Brain Health + Tips on Boosting Gut Health and Overcoming Food Sensitivities with GI Specialist Dr. Will Bulsiewicz appeared first on Amazing Health Advances.

Should Endocrine Dysruptor Bisphenol A (BPA) Be Banned Completely?

AHA Publisher — Mon, 18 Nov 2019 08:00:51 +0000

Michael Greger M.D. FACLM via Nutrition Facts – “The number of new chemicals is increasing exponentially, with approximately 12,000 new substances added daily…”—yet data aren’t available on the hazards of even some of the high-volume chemicals. Bisphenol A (BPA) is one of the highest volume chemicals, with billions of pounds produced each year. Studies have raised concerns about its possible implication in the cause of certain chronic diseases, such as diabetes, obesity, reproductive disorders, cardiovascular diseases, birth defects, chronic respiratory diseases, kidney diseases, and breast cancer. Given this, BPA is the topic of my video Why BPA Hasn’t Been Banned. A new study on the health implications of BPA comes out nearly every week. BPA was first developed over a hundred years ago as a synthetic estrogen, but it wasn’t until the 1950s that industry realized it could be used to make polycarbonate plastic, and “BPA rapidly became one of the most produced and used chemicals worldwide, even though it was a recognized synthetic estrogen” with hormonal effects. About a billion pounds are also used to line food and beverage cans, especially for tuna and condensed soups. Today, nearly all of us, including our children, have BPA in our bodies, but not to worry: The government says up to 50 µg/kg per day is safe. Even those working in Chinese BPA factories don’t get exposed to more than 70 times lower than that so-called safety limit. Why then did exposure seem to affect male workers’ sperm counts? In the United States, the general population gets less than a thousand times lower than the safety limit, yet, even at those incredibly low doses, we still seem to be seeing adverse effects on thyroid function, weight control, blood sugar control, cardiovascular disease, liver function, and immune function. Indeed, “[t]he fact that there are significant adverse effects in populations exposed to BPA at concentrations [thousands of] times lower than the TDI [tolerable daily limit]…indicates that the safe exposure to BPA may be much lower than previously thought in humans.” Despite this, the limit hasn’t been changed. BPA has been banned from “baby bottles and sippy cups,” but nearly unlimited doses are still apparently okay for everyone else. What’s the disconnect? It has to do with the fascinating world of low-dose effects of hormone-disrupting chemicals. “For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional concepts in toxicology, in particular the dogma of ‘the dose makes the poison'”—that is, the concept “that lower exposures to a hazardous compound will therefore always generate lower risks.” Indeed, that is the core assumption underlying our system of chemical safety testing. Researchers start giving animals in laboratories a super-high dose and then keep lowering the dosage until whatever adverse effects that had occurred disappear. Then, they add a safety buffer and assume everything below that dose should be okay, assuming a straight line showing the higher the dose, the higher the effect. However, hormone-disrupting chemicals can have all sorts of curious curves. How is it possible that something could have more of an effect at a lower dose? A study was done to see whether BPA suppressed an obesity-protective hormone in fat samples taken from breast reduction and tummy tuck patients. At 100 nanomoles of BPA, hormone levels were no lower than they were at 0nM of BPA. And, since most people have levels between 1 and 20, BPA was considered to be safe. But, although there was no suppression at 0 and no suppression at 100, at the levels actually found in people’s bodies, BPA appeared to cut hormone release nearly in half. As the world’s oldest, largest, and most active organization devoted to research on hormones concluded, “even infinitesimally low levels of exposure—indeed, any level of exposure at all—may cause [problems].” In fact, it may come to nearly $3 billion in problems every year, counting the estimated effects of BPA on childhood obesity and heart disease alone. There are alternatives the industry can use. The problem, though, is that they may cost companies two cents more. This article has been modified. To read the original article click here. To read more articles from Dr. Greger click here.

The post Should Endocrine Dysruptor Bisphenol A (BPA) Be Banned Completely? appeared first on Amazing Health Advances.