Weight Loss Surgery Undergone Before Pregnancy May Influence Children’s Weight Gain

The AHA! Team — Thu, 05 Sep 2024 08:29:54 +0000

The Endocrine Society via EurekAlert! – BOSTON—The type of weight loss surgery women undergo before becoming pregnant may affect how much weight their children gain in the first three years of life, suggests a study being presented Monday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. Researchers found children born to women who underwent the bariatric procedure known as sleeve gastrectomy before they became pregnant gain more weight per month on average in the first three years of life compared with children born to women who had the less common Roux-en-Y gastric bypass weight loss procedure. “Either the extent of pre-pregnancy weight loss or the metabolic changes from Roux-en-Y gastric bypass may be favorable for the children’s early childhood weight gain,” said researcher Vidhu Thaker, M.D., of the Columbia University Irving Medical Center in New York, N.Y. Maternal obesity is a risk factor for obesity in children. Women are more likely to conceive following weight loss procedures, but less is known about the early growth of the children born after pre-pregnancy weight loss procedures. Sleeve gastrectomy and Roux-en-Y gastric bypass are two of the more common types of weight loss surgery, also known as bariatric and metabolic surgery. These surgeries result in sustained weight loss and improve the body’s metabolism in the majority of patients. In vertical sleeve gastrectomy (also called gastric sleeve surgery), a surgeon removes most of the stomach, leaving only a banana-shaped section that is closed with staples. By removing a part of the stomach that makes hormones that drive hunger, this procedure also decreases appetite. In gastric bypass, the surgeon divides the stomach into two parts, sealing off the upper section from the lower. The surgeon then connects the upper stomach directly to the lower section of the small intestine. This creates a shortcut for food, bypassing part of the stomach and the small intestine. Skipping these parts of the digestive tract means the body absorbs fewer calories and nutrients. The researchers examined the weight and length of offspring born after pre-pregnancy weight loss procedures in the first three years of life. The study used data from 20,515 deliveries over three years, of which 450 had pre-pregnancy weight loss procedures. Among the mothers who underwent weight loss surgery, 57% had sleeve gastrectomy and 41% had Roux-en-Y gastric bypass. Long-term weight and length data were available for about half of the babies in each group. The researchers found there was no difference in birth weight among the babies born after weight loss surgery. The pace of weight gain was higher in those born after pre-pregnancy sleeve gastrectomy compared to those born following Roux-en-Y gastric bypass, while adjusting for several other variables including pre-pregnancy body mass index. “While we did not have data on the magnitude of weight loss following bariatric surgery, Roux-en-Y gastric bypass is known to have higher weight loss and metabolic changes compared to sleeve gastrectomy,” Thaker noted. The authors concluded that the either the extent of pre-pregnancy weight loss or the metabolic changes from Roux-en-Y gastric bypass may be favorable for the offspring’s early childhood weight trajectory. “A study of the mechanisms underlying the associations of the sustained pre-pregnancy weight loss and the offspring’s early life growth may also apply to other methods of weight loss, including the most recently approved anti-obesity medications,” Thaker said. # # # Endocrinologists are at the core of solving the most pressing health problems of our time, from diabetes and obesity to infertility, bone health, and hormone-related cancers. The Endocrine Society is the world’s oldest and largest organization of scientists devoted to hormone research and physicians who care for people with hormone-related conditions. The Society has more than 18,000 members, including scientists, physicians, educators, nurses and students in 122 countries. To learn more about the Society and the field of endocrinology, visit our site at www.endocrine.org. Follow us on Twitter at @TheEndoSociety and @EndoMedia. To read the original article click here.

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New Study Shows Weight-Loss Surgery Significantly Cut Risk of Severe Complications From COVID-19 in Patients with Obesity

AHA Publisher — Tue, 04 Jan 2022 08:00:35 +0000

American Society for Metabolic and Bariatric Surgery (ASMBS) via Newswise – NEWBERRY, FL – Dec. 29, 2021 – Adults with obesity who had weight-loss surgery and achieved substantial weight loss prior to contracting COVID-19 reduced their risk for developing severe outcomes from the infection by 60% compared to those who did not have surgery, according to a new Cleveland Clinic study published online today in the journal JAMA Surgery. According to the U.S. Centers for Disease Control and Prevention (CDC), having obesity increases the risk of severe illness from COVID. “This is an important study that shows that patients with obesity who had bariatric surgery and subsequently developed COVID-19 had greatly reduced their risk for hospitalization, supplemental oxygen, and severe infection compared to similar patients that did not have bariatric surgery,” said Shanu N. Kothari, MD, president of the American Society for Metabolic and Bariatric Surgery (ASMBS), who was not involved in the study. “This timely study should serve as further motivation for patients and their doctors to treat the disease of obesity before potentially having to treat its dangerous consequences.” Obesity is linked to more than 40 diseases including type 2 diabetes, hypertension, heart disease, stroke, sleep apnea, osteoarthritis and at least 13 different types of cancer. The CDC reports that from 1999 –2000 through 2017 –2018, the prevalence of obesity in the U.S. increased from 30% to 42% and severe obesity increased from 4.7% to 9.2%. Metabolic/bariatric surgery has been shown to be the most effective and durable treatment for severe obesity, resulting in significant weight loss and resolution or improvements in diabetes, heart disease, sleep apnea and many other diseases. The safety profile of laparoscopic bariatric surgery is comparable to some of the safest and most commonly performed surgeries in the U.S. including gallbladder surgery, appendectomy and knee replacement. An estimated 256,000 bariatric surgeries were performed in 2019, according to the ASMBS, which represents less than 1 percent of the currently eligible surgical population by BMI. Nearly 60% were sleeve gastrectomies, an increasingly popular procedure that involves removing most of the stomach and shaping the remainder into a tube or sleeve, restricting the amount of food it can hold. About 18% of procedures were gastric bypass. To read the original article click here.

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Weight Loss Surgery Undergone Before Pregnancy May Influence Children’s Weight Gain

New Study Shows Weight-Loss Surgery Significantly Cut Risk of Severe Complications From COVID-19 in Patients with Obesity