diagnostic test Archives - Amazing Health Advances https://amazinghealthadvances.net/tag/diagnostic-test/ Your hub for fresh-picked health and wellness info Tue, 21 Apr 2020 06:16:45 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.1 https://amazinghealthadvances.net/wp-content/uploads/2019/08/AHA_Gradient_Bowl-150x150.jpg diagnostic test Archives - Amazing Health Advances https://amazinghealthadvances.net/tag/diagnostic-test/ 32 32 Diagnostic Biosensor Quickly Detects SARS-CoV-2 from Nasopharyngeal Swabs https://amazinghealthadvances.net/diagnostic-biosensor-quickly-detects-sars-cov-2-from-nasopharyngeal-swabs-6490/#utm_source=rss&utm_medium=rss&utm_campaign=diagnostic-biosensor-quickly-detects-sars-cov-2-from-nasopharyngeal-swabs-6490 https://amazinghealthadvances.net/diagnostic-biosensor-quickly-detects-sars-cov-2-from-nasopharyngeal-swabs-6490/#respond Tue, 21 Apr 2020 07:00:24 +0000 http://amazinghealthadvances.net/?p=8556 American Chemical Society via EurekAlert – According to many experts, early diagnosis and management are critical for slowing the spread of SARS-CoV-2, the new coronavirus that causes COVID-19. Therefore, the race is on to develop diagnostic tests for the virus that are faster, easier and more accurate than existing ones. Now, researchers reporting in ACS Nano have developed a field-effect transistor-based biosensor that detects SARS-CoV-2 in nasopharyngeal swabs from patients with COVID-19, in less than one minute. Currently, most diagnostic tests for COVID-19 rely on a technique called real-time reverse transcription-polymerase chain reaction (RT-PCR), which amplifies SARS-CoV-2 RNA from patient swabs so that tiny amounts of the virus can be detected. However, the method takes at least 3 hours, including a step to prepare the viral RNA for analysis. Edmond Changkyun Park, Seung Il Kim and colleagues wanted to develop a faster diagnostic test that could analyze patient samples directly from a tube of buffer containing the swabs, without any sample preparation steps. The team based their test on a field-effect transistor — a sheet of graphene with high electronic conductivity. The researchers attached antibodies against the SARS-CoV-2 spike protein to the graphene. When they added either purified spike protein or cultured SARS-CoV-2 virus to the sensor, binding to the antibody caused a change in the electrical current. Next, the team tested the technique on nasopharyngeal swabs collected from patients with COVID-19 or healthy controls. Without any sample preparation, the sensor could discriminate between samples from sick and healthy patients. The new test was about 2-4 times less sensitive than RT-PCR, but different materials could be explored to improve the signal-to-noise ratio, the researchers say. This article has been modified. To read the original article click here.

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