dementia and old age Archives - Amazing Health Advances

Ancient Herb Shows Promise in Fighting Dementia

The AHA! Team — Mon, 16 Dec 2024 06:16:14 +0000

Osaka Metropolitan University via News-Medical – Attempts to discover a breakthrough dementia drug might be drawing attention these days, but traditional medicinal products can offer hints for preventive medicine. Traditional medicinal products can offer hints for preventive medicine A research group led by Specially Appointed Professor Takami Tomiyama of Osaka Metropolitan University’s Graduate School of Medicine has found that administering the dried seeds of a type of jujube called Ziziphus jujuba Miller var. spinosa, used as a medicinal herb in traditional Chinese medicine, holds promise in restoring cognitive and motor function in model mice. By administering hot water extracts of Zizyphi spinosi semen to model mice with Alzheimer’s disease, frontotemporal dementia, Parkinson’s disease, and dementia with Lewy bodies, the team found that cognitive and motor functions were restored. Furthermore, when the seeds were simply crushed into powder and administered to the model mice, the team discovered that the cognitive function of the model mice recovered to a level above that of control mice. In addition, the powders apparently suppressed cellular aging in older mice and improved their cognitive function to a similar level as younger mice. Previously, members of the research team reported separately that the pathology of dementia in model mice improved with cognitive and motor functions restored after using the Hawaiian herb mamaki and the Chinese herb Acorus gramineus. “The results of our research will hopefully make it possible to develop dementia prevention products that middle-aged and elderly people can take at their own discretion.” -Takami Tomiyama, Professor, Graduate School of Medicine, Osaka Metropolitan University The findings are currently available as a reviewed preprint in eLife. Source: Osaka Metropolitan University Journal reference: Umeda, T., et al. (2024) Simply crushed Zizyphi spinosi semen prevents neurodegenerative diseases and reverses age-related cognitive decline in mice. doi.org/10.7554/elife.100737.1. To read the original article click here.

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How to Care for a Loved One with Dementia

The AHA! Team — Wed, 27 Nov 2024 06:37:37 +0000

University of Miami via Newswise – More than 11 million Americans are tasked with the responsibility of taking care of someone with cognitive decline. A diagnosis of Alzheimer’s disease or related dementias (ADRD) for an aging loved one can be devastating for a family. In 2023, it was estimated that 6.7 million Americans of all ages had the diagnosis of Alzheimer’s disease. More than 11 million people care for a loved one with Alzheimer’s or a related dementia, according to the Centers for Disease Control and Prevention, and about 80 percent of those patients are cared for in the home. Dr. Elizabeth Crocco is a geriatric psychiatrist and the medical director of the Memory Disorders Clinic Center for Cognitive Neuroscience and Aging at the University of Miami Miller School of Medicine. Over the course of her career, she has seen thousands of patients and their families. She reports that for some families, the diagnosis of ADRD can be helpful because it ultimately can explain that the illness is not just due to normal aging. For others, a diagnosis can be scary. “It can be frightening because they know that it is irreversible and that it progresses,” she said. “The idea that the person will lose part of who they are, not just cognitively, but part of their essential personality, brings up a lot of feelings.” Cognitive impairment is the hallmark feature of ADRD, but these illnesses can also have behavioral changes. These include agitation, irritability, depression, and anxiety. It is important for care providers to learn how to handle these situations while also maintaining their own mental health, she said. In her clinic, Crocco and her team work with care providers so that they understand the condition and can better manage its symptoms. This includes how to communicate with the loved one. “The memory issue is not the only problem that is making one’s loved one suffer, and a family member can have a difficult time,” she said. “It is the psychiatric and behavioral symptoms that are often the most difficult to deal with: depression, anxiety, anger issues, agitation, along with resistance to care and help.” Medications, of course, can help, but effective and consistent caregiving is paramount in coping with a patient with ADRD. Crocco offered some helpful tips that can make taking care of an individual with ADRD easier: Establish a routine Consistency is key. Chaotic home situations are not kind to people with cognitive impairment. Traveling is a change of routine that can lead to more behavioral problems and confusion. If they resist a task, try not to force them to do it. Wait an hour or more as their attitude may change later. Keep calm Keeping calm and composed is important when dealing with a loved one with ADRD. Also, remember that your reality might not be theirs, and you need to be respectful. Crocco’s mother had dementia. She tells this story: “One time I was at my mother’s house, and I had left a piece of pizza on the stove. My mother began screaming and cursing because there was a piece of pizza on the stove, and it upset her. I took the pizza off the stove, washed the area down, and I said: ‘I am so sorry, Mom, that I upset you.’ She calmed down immediately.” Sundowning It can happen earlier than expected, in the late afternoon. During this time, for both biological and situational reasons, an ADRD individual may become more confused, disoriented, agitated, and paranoid, as well as anxious and fearful. It is important for loved ones to predict patterns to minimize problems behaviorally without always opting for medications. Therapeutic fibbing Cognitive decline often leaves the person with memories of the past. If a loved one has forgotten that someone is deceased, they may repeatedly ask about them. At times, it might be better to let them believe that they are still alive. “What is the alternative?” asked Crocco. “Letting them relive the death over and over again?” Often arguing with a loved one with Alzheimer’s is a losing proposition and only leads to agitation and discord. “You argue and you lose,” said Crocco. Use music and pets Often introducing preferred music from the loved ones’ era can assist in preventing behavioral problems and be very entertaining and enjoyable. Bringing in pets for ADRD individuals to interact with can also assist. It is well known that having animal or pet interactions can lower ones’ stress level as well as blood pressure, said Crocco. Seek help An adult day care center is a good alternative to help a care provider with the help of a loved one with ADRD, said Crocco. Besides providing social interaction and dementia care during the day, it also affords the caretaker time to work or rest, said Crocco. Learn more about the Memory Disorders Clinic at the University of Miami Health System. To read the original article click here.

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Greater Body Fat Found to Be a Risk Factor for Reduced Cognitive Function

AHA Publisher — Wed, 02 Feb 2022 08:00:54 +0000

McMaster University via News-Medical – A new study has found that greater body fat is a risk factor for reduced cognitive function, such as processing speed, in adults. Even when the researchers took cardiovascular risk factors (such as diabetes or high blood pressure) or vascular brain injury into account, the association between body fat and lower cognitive scores remained. This suggests other not yet confirmed pathways that linked excess body fat to reduced cognitive function. In the study, 9,166 participants were measured by bioelectrical impedance analysis to assess their total body fat. As well, 6,733 of the participants underwent magnetic resonance imaging (MRI) to measure abdominal fat packed around the organs known as visceral fat, and the MRI also assessed vascular brain injury – areas in the brain affected by reduced blood flow to the brain. The results were published today in JAMA Network Open. “Our results suggest that strategies to prevent or reduce having too much body fat may preserve cognitive function.” Sonia Anand, lead author, professor of medicine of McMaster University’s Michael G. DeGroote School of Medicine and vascular medicine specialist at Hamilton Health Sciences (HHS) She is also a senior scientist of the Population Health Research Institute of McMaster and HHS. She added that “the effect of increased body fat persisted even after adjusting for its effect on increasing cardiovascular risk factors like diabetes and high blood pressure, as well as vascular brain injury, which should prompt researchers to investigate which other pathways may link excess fat to reduced cognitive function.” Co-author Eric Smith, a neurologist, scientist and an associate professor of clinical neurosciences at the University of Calgary, said that “preserving cognitive function is one of the best ways to prevent dementia in old age. This study suggests that one of the ways that good nutrition and physical activity prevent dementia may be by maintaining healthy weight and body fat percentage.” Smith is head of the brain core lab for the two population cohorts used for this new analysis– the Canadian Alliance for Healthy Hearts and Minds (CAHHM) and PURE Mind- a sub-study of the large, international Prospective Urban Rural Epidemiological (PURE) study. The participants were in the age range of 30 to 75 with an average age of about 58. Just over 56% were women; they all lived in either Canada or Poland. The majority were White European origin, with about 16% other ethnic backgrounds. Individuals with known cardiovascular disease were excluded. To read the original article click here.

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