cruciferous vegetable Archives - Amazing Health Advances

New Scientific Review: Broccoli Compounds Act Against Cancer, but Western Medicine Ignores Its Benefits

AHA Publisher — Tue, 14 Dec 2021 08:00:18 +0000

Lori Alton via NaturalHealth365 – For almost three decades, forward-thinking scientists have been investigating the potential of sulforaphane – found in cruciferous vegetables such as broccoli and Brussels sprouts – to combat cancer. In a new review published in Frontiers in Nutrition, the authors evaluated sulforaphane research while shedding light on the multiple mechanisms through which this potent natural compound targets cancer cells. Yet, despite very promising results, the team noted there has been a delay in Western medicine’s acceptance of the therapeutic potential of sulforaphane. Why are conventional oncologists “dragging their feet” on this?! Let’s see what the research reveals. Preliminary Studies Showcase Anticancer Effects of Sulforaphane in Broccoli Cell and animal studies have shown that sulforaphane has anticancer effects, with the ability to cause apoptosis, or pre-programmed “suicide,” in cancer cells. Sulforaphane has also been shown to inhibit the ability of cancer to invade other cells and to slow the progression of lesions into malignant tumors. (As it turns out, sulforaphane has the capacity to inhibit angiogenesis, the formation of new blood vessels carrying oxygen and nutrients to tumors). Research has shown that a high dietary intake of cruciferous vegetables – such as broccoli, kale, cabbage, and Brussels sprouts – is associated with a lower risk of cancers. And, a recent (2020) review of clinical studies indicates that cruciferous vegetables rich in sulforaphane may reduce the risk of breast cancer. And, according to the U.S. Centers for Disease Control and Prevention, breast cancer currently claims the lives of over 42,000 women a year in the United States. No doubt, more women need to hear about the health benefits of cruciferous vegetables. Hope Against a Lethal Disease: Sulforaphane in Broccoli Inhibits Triple-Negative Breast Cancer Cells, While Potentially Setting the Stage for Treatment Triple-negative breast cancer is among the deadliest of all breast cancers – and there are currently no effective therapies. However, researchers say that sulforaphane works against the signaling pathways needed for the development and metastasis of this type of cancer. A 2019 study published in Cancer Prevention Research revealed that sulforaphane suppressed the growth and tumorsphere formation of triple-negative breast cancer stem cells, both in vitro (in test tubes) and in vivo (in living creatures). One of the reasons for the virulence of triple-negative breast cancers is that the cells don’t have the receptors that allow effective treatments to be given. But, a meta-analysis of studies found that sulforaphane – along with epigallocatechin gallate, a flavonoid found in green tea – restored estrogen receptors in triple-negative breast cancer cells, thereby potentially “opening the door” for treatment! And, the encouraging research is not limited to breast cancer. In a study published in Oncotarget – Peer-Reviewed Oncology and Cancer Research, scientists found that sulforaphane significantly inhibited thyroid cancer cell proliferation as well – leading them to label it a “potentially effective antitumor agent.“ Bureaucratic Obstacles and “Red Tape” Have Slowed Sulforaphane Research In the Frontiers of Nutrition review, the authors discussed the delay in sulforaphane’s acceptance as a cancer treatment – along with the delay in the acceptance of cruciferous vegetables as a preventive, and possibly therapeutic, intervention. Until the beginning of the 21st century, pure sulforaphane – which was used in many of the studies – was considered a drug by the Food and Drug Administration, meaning trials had to be strictly regulated. In addition, while sulforaphane had obvious anticancer effects, it was difficult for researchers to “tease out” exactly which other nutrients in cruciferous vegetables (such as flavonoids, anthocyanins, carotenoids, fiber, vitamins, and minerals) might be acting against cancer as well. As if that doesn’t make the research tricky enough, cruciferous vegetables contain varying amounts of glucoraphanin and other anticancer constituents – depending on the species, temperature, time of harvest, light, and soil. Calling the current therapeutic use of plant compounds “woefully inadequate,” the team suggested supporting health and preventing disease through the promotion and marketing of “healthy diets rich in fresh fruits and vegetables.” They also called for more research to explore the effects of sulforaphane. Good News: Sulforaphane Precursors Help Absorbability Three decades of research have illustrated the cancer-fighting abilities of sulforaphane. However, experts point out that you can’t just “pop a pill” of this compound – as stomach acids would quickly destroy it. So, how do we get this precious anticancer molecule into our bodies? Researchers say this requires the use of a “precursor” known as glucoraphanin, which is converted to sulforaphane in the digestive tract. And, one more “player”- an enzyme known as myrosinase – is needed. This natural plant chemical activates sulforaphane upon being ripped, cut, or chewed. While mature broccoli lack sulforaphane-boosting power, fresh, raw broccoli sprouts possess a much greater ability than mature florets to boost blood levels. (We’re talking 10 to 100 times more!) But: food-borne pathogens are sometimes found in broccoli sprouts, causing many natural health experts to warn that they require extensive decontamination before they can be eaten. Fortunately, supplementary glucoraphanin and myrosinase are available in enteric caplets, which are coated to avoid stomach acids. Before supplementing, however, consult your integrative doctor or health coach for guidance. Of course – despite their limitations in raising sulforaphane levels – cruciferous vegetables have consistently been linked with lower cancer rates, as well as with other health benefits. Eating generous amounts of these vegetables should be part of your daily health routine. Unfortunately, conventionally-trained nutrition “experts” barely acknowledges the existence of plant chemicals – and physician training includes almost no nutrition education. The reviewers would clearly like to see this situation change – and called for a complete “reinvention of the country’s healthcare,” with phytochemicals, such as sulforaphane, at the forefront. Let’s see if anyone is listening. Sources for this article include: LifeExtension.com NIH.gov NIH.gov CDC.gov To read the original article click here.

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Eating Raw Sauerkraut Offers More Health Benefits Than You Think

AHA Publisher — Tue, 23 Feb 2021 08:00:03 +0000

Karen Sanders via NaturalHealth365 – Sauerkraut, that familiar hot dog condiment, may not have the beauty of garnet-colored raspberries or the sweet, refreshing flavor of tropical fruits. But the latest scientific research tells us that freshly-made organic sauerkraut is a true superfood that boosts the immune system, promotes intestinal health, and helps prevent cancer in many ways. A recently published study in Critical Reviews in Food Science and Nutrition found that fermented foods such as raw sauerkraut contain chemical compounds and beneficial bacteria that offer a wide array of health benefits due to their anticancer, anti-microbial, and antioxidant activities. How Does Sauerkraut Prevent Cancer? Cabbage, the cruciferous vegetable from which sauerkraut is made, is already valued by natural food experts and nutritionists for its sky-high amounts of anticarcinogenic bioactive compounds. In fact, the glucosinolates in cabbage help activate the body’s own antioxidants, which fight the lipid oxidation and inflammation that can trigger cancer and heart disease. Additionally, the process of lacto-fermentation involved in turning cabbage to sauerkraut produces beneficial bacteria. It unleashes even more potent anti-inflammatory cancer-fighting substances – taking the health benefits to a whole new level and helping to ward off cancers of the prostate, bladder, and breast. Here Is Why Raw Sauerkraut Helps Ward Off Cancer According to the author and natural health expert Sandor Ellix Katz, the process of lactic fermentation not only preserves the nutrients in food but breaks them down. Hence, they are even more healthful and easily digested. But what, exactly, is lactic fermentation, and why is it beneficial? Although the term sounds somewhat technical, it is actually the natural result of layering shredded cabbage in water with salt, then letting existing bacteria on the cabbage do the work. The end product – sauerkraut – contains more live probiotic cultures than yogurt. One result of lacto-fermentation is to create large amounts of beneficial lactobacillus bacteria, which support friendly flora in the intestinal tract. Another is the release of isothiocyanate compounds from existing glucosinolate; these isothiocyanates have shown such pronounced anticarcinogenic effects in cellular, laboratory, and human studies. Impressive Science Behind the Benefits of Sauerkraut In an October 2002 article in the Journal of Agricultural and Food Chemistry, researchers announced that they had isolated isothiocyanates in sauerkraut and that these compounds had cancer-protective effects in animal studies. They added that clinical research would be required to determine if these effects extended to humans. In the twelve years since the article was published, many studies on sauerkraut and sauerkraut juice show that it lowers cancer risk in humans – particularly for cancers of the breast and colon. In a study published in 2011 in the British Journal of Nutrition, researchers noted that the detoxifying enzymes in sauerkraut juice have an anticarcinogenic effect on kidney and liver cancer cells and added that sauerkraut juice increased levels of glutathione-S-transferase – considered a chemoprotective agent. Sauerkraut’s Probiotic Cultures Fight Cancer in Multiple Ways In a review published in 2006 in the Journal of Applied Microbiology, researchers stated that lactic acid bacteria could prevent certain types of cancer – including colon and bladder cancer – and categorized how probiotic cultures help torpedo cancer cell development. Not only do probiotic cultures detoxify ingested carcinogens and stimulate the immune system, but they also create an environment hostile to carcinogenic compounds. Specifically, they create organic compounds – including butyrate – that inhibit tumor growth and encourage the apoptosis, or programmed cell death, of cancer cells. The authors theorized that probiotic cultures might also suppress bacteria responsible for turning procarcinogens into carcinogens and added that lactobacillus could bind to mutagenic compounds in the intestine. What Is the Best Type of Sauerkraut to Prevent Cancer? Buy only sauerkraut that is freshly made, raw, unpasteurized, and organic; your best bet is to look for it in the refrigerated aisle of local markets or farmers’ markets. Avoid canned sauerkraut, which offers far fewer nutrients and probiotic benefits. Most experts recommend consuming at least 1 and ½ cups of sauerkraut 4 to 5 times a week; 2-cup servings, of course, are even healthier. One cautionary note: raw sauerkraut produces raffinose, a trisaccharide that can’t be broken down in the intestine. Bloating and flatulence can result but should subside as your body becomes accustomed to this healthful food. Simply put, fresh lacto-fermented sauerkraut, packed with cancer-fighting compounds and antioxidants and high in healthful dietary fiber, is a superb nutritional choice. Sources for this article include: NIH.gov Wiley.com NIH.gov To read the original article click here. For more articles from NaturalHealth365 click here.

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