cannabis Archives - Amazing Health Advances

As Cannabis Users Age, Health Risks Appear to Grow

The AHA! Team — Wed, 13 Aug 2025 05:57:54 +0000

KFF Health News via News-Medical – “If you view cannabis as a medicine, you should be open to the idea that there are groups who probably shouldn’t use it and that there are potential adverse effects from it,” – “Because that is true of all medicines.” A cautionary tale Benjamin Han, a geriatrician and addiction medicine specialist at the University of California-San Diego, tells his students a cautionary tale about a 76-year-old patient who, like many older people, struggled with insomnia. “She had problems falling asleep, and she’d wake up in the middle of the night,” he said. “So her daughter brought her some sleep gummies” — edible cannabis candies. “She tried a gummy after dinner and waited half an hour,” Han said. Feeling no effects, she took another gummy, then one more — a total of four over several hours. Han advises patients who are trying cannabis to “start low; go slow,” beginning with products that contain just 1 or 2.5 milligrams of tetrahydrocannabinol, or THC, the psychoactive ingredient that many cannabis products contain. Each of the four gummies this patient took, however, contained 10 milligrams. The woman started experiencing intense anxiety and heart palpitations. A young person might have shrugged off such symptoms, but this patient had high blood pressure and atrial fibrillation, a heart arrhythmia. Frightened, she went to an emergency room. Lab tests and a cardiac work-up determined the woman wasn’t having a heart attack, and the staff sent her home. Her only lingering symptom was embarrassment, Han said. But what if she’d grown dizzy or lightheaded and was hurt in a fall? He said he has had patients injured in falls or while driving after using cannabis. What if the cannabis had interacted with the prescription drugs she took? “As a geriatrician, it gives me pause,” Han said. “Our brains are more sensitive to psychoactive substances as we age.” Thirty-nine states and the District of Columbia now allow cannabis use for medical reasons, and in 24 of those states, as well as the district, recreational use is also legal. As older adults’ use climbs, “the benefits are still unclear,” Han said. “But we’re seeing more evidence of potential harms.” A wave of recent research points to reasons for concern for older users, with cannabis-related emergency room visits and hospitalizations rising, and a Canadian study finding an association between such acute care and subsequent dementia. Older people are more apt than younger ones to try cannabis for therapeutic reasons: to relieve chronic pain, insomnia, or mental health issues, though evidence of its effectiveness in addressing those conditions remains thin, experts said. In an analysis of national survey data published June 2 in the medical journal JAMA, Han and his colleagues reported that “current” cannabis use (defined as use within the previous month) had jumped among adults age 65 or older to 7% of respondents in 2023, from 4.8% in 2021. In 2005, he pointed out, fewer than 1% of older adults reported using cannabis in the previous year. What’s driving the increase? Experts cite the steady march of state legalization — use by older people is highest in those states — while surveys show that the perceived risk of cannabis use has declined. One national survey found that a growing proportion of American adults — 44% in 2021 — erroneously thought it safer to smoke cannabis daily than cigarettes. The authors of the study, in JAMA Network Open, noted that “these views do not reflect the existing science on cannabis and tobacco smoke.” The cannabis industry also markets its products to older adults. The Trulieve chain gives a 10% discount, both in stores and online, to those it calls “wisdom” customers, 55 or older. Rise Dispensaries ran a yearlong cannabis education and empowerment program for two senior centers in Paterson, New Jersey, including field trips to its dispensary. The industry has many satisfied older customers. Liz Logan, 67, a freelance writer in Bronxville, New York, had grappled with sleep problems and anxiety for years, but the conditions grew particularly debilitating two years ago, as her husband was dying of Parkinson’s disease. “I’d frequently be awake until 5 or 6 in the morning,” she said. “It makes you crazy.” Looking online for edible cannabis products, Logan found that gummies containing cannabidiol, known as CBD, alone didn’t help, but those with 10 milligrams of THC did the trick without noticeable side effects. “I don’t worry about sleep anymore,” she said. “I’ve solved a lifelong problem.” But studies in the United States and Canada, which legalized nonmedical cannabis use for adults nationally in 2018, show climbing rates of cannabis-related health care use among older people, both in outpatient settings and in hospitals. California In California, for instance, cannabis-related emergency room visits by those 65 or older rose, to 395 per 100,000 visits in 2019 from about 21 in 2005. In Ontario, acute care (meaning emergency visits or hospital admissions) resulting from cannabis use increased fivefold in middle-aged adults from 2008 to 2021, and more than 26 times among those 65 and up. “It’s not reflective of everyone who’s using cannabis,” cautioned Daniel Myran, an investigator at the Bruyère Health Research Institute in Ottawa and lead author of the Ontario study. “It’s capturing people with more severe patterns.” But since other studies have shown increased cardiac risk among some cannabis users with heart disease or diabetes, “there’s a number of warning signals,” he said. Cannabis use disorder For example, a disturbing proportion of older veterans who currently use cannabis screen positive for cannabis use disorder, a recent JAMA Network Open study found. As with other substance use disorders, such patients “can tolerate high amounts,” said the lead author, Vira Pravosud, a cannabis researcher at the Northern California Institute for Research and Education. “They continue using even if it interferes with their social or work or family obligations” and may experience withdrawal if they stop. Among 4,500 older veterans (with an average age of 73) seeking care at Department of Veterans Affairs health facilities, researchers found that more than 10% had reported cannabis use within the previous 30 days. Of those, 36% fit the criteria for mild, moderate, or severe cannabis use disorder, as established in the Diagnostic and Statistical Manual of Mental Disorders. VA patients differ from the general population, Pravosud noted. They are much more likely to report substance misuse and have “higher rates of chronic diseases and disabilities, and mental health conditions like PTSD” that could lead to self-medication, she said. Current VA policies don’t require clinicians to ask patients about cannabis use. Pravosud thinks that they should. Moreover, “there’s increasing evidence of a potential effect on memory and cognition,” said Myran, citing his team’s study of Ontario patients with cannabis-related conditions going to emergency departments or being admitted to hospitals. Comparisons Compared with others of the same age and sex who were seeking care for other reasons, research shows these patients (ages 45 to 105) had 1.5 times the risk of a dementia diagnosis within five years, and 3.9 times the risk of that for the general population. Even after adjusting for chronic health conditions and sociodemographic factors, those seeking acute care resulting from cannabis use had a 23% higher dementia risk than patients with noncannabis-related ailments, and a 72% higher risk than the general population. None of these studies were randomized clinical trials, the researchers pointed out; they were observational and could not ascertain causality. Some cannabis research doesn’t specify whether users are smoking, vaping, ingesting or rubbing topical cannabis on aching joints; other studies lack relevant demographic information. Safer modes of consumption “It’s very frustrating that we’re not able to provide more individual guidance on safer modes of consumption, and on amounts of use that seem lower-risk,” Myran said. “It just highlights that the rapid expansion of regular cannabis use in North America is outpacing our knowledge.” Still, given the health vulnerabilities of older people, and the far greater potency of current cannabis products compared with the weed of their youth, he and other researchers urge caution. “If you view cannabis as a medicine, you should be open to the idea that there are groups who probably shouldn’t use it and that there are potential adverse effects from it,” he said. “Because that is true of all medicines.” Source: KFF Health News To read the original article click here.

The post As Cannabis Users Age, Health Risks Appear to Grow appeared first on Amazing Health Advances.

Daily Cannabis Use Linked to Public Health Burden

The AHA! Team — Mon, 28 Apr 2025 05:24:00 +0000

George Washington University via Newswise – A new study analyzes the disease burden and the risk factors for severity among people who suffer from a condition called cannabinoid hyperemesis syndrome (Washington Feb. 20, 2025) Cannabinoid hyperemesis syndrome Researchers at the George Washington University say the condition occurs in people who are long-term regular consumers of cannabis and causes nausea, uncontrollable vomiting and excruciating pain in a cyclical pattern that often leads to repeated trips to the hospital. “This is one of the first large studies to examine the burden of disease associated with this cannabis-linked syndrome,” says Andrew Meltzer, professor of emergency medicine at the GW School of Medicine & Health Sciences and lead author of the study. “Our findings suggest that cannabinoid hyperemesis syndrome could represent a costly and largely hidden public health problem.” Many experts say that the condition is on the rise While the exact prevalence of the condition is unknown, many experts say that the condition is on the rise as the number of daily or near daily users of cannabis has increased in the US. To assess the burden of disease, Meltzer and his colleagues conducted a survey of 1,052 people who report suffering from cannabinoid hyperemesis syndrome. The researchers asked questions about frequency of use, duration of the habit, the age they started using the drug, and need for emergency department or hospital care. Key findings of the study: 85% reported at least 1 emergency department visit and 44% reported at least 1 hospitalization associated with the hyperemesis symptoms. Early age of cannabis initiation was associated with higher odds of emergency department visits. Daily use of cannabis before the onset of the syndrome was nearly universal, with over 40% of respondents reporting they used marijuana more than 5 times a day. Prolonged use was common with 44% reporting using regularly for more than 5 years before onset of syndrome. The new research suggests that the condition may impose a heavy burden on individuals who suffer from it as it often results in pain, vomiting and costly trips to the hospital. Emergency room doctors can stabilize the patient and help alleviate the acute symptoms but the only known way to stop the episodes of excruciating abdominal pain and repeated vomiting is to stop using cannabis, Meltzer says. A substantial risk of this painful and costly condition Although this study had some limitations, including self-reported use of cannabis, Meltzer says it suggests a substantial risk of this painful and costly condition, especially for users who begin daily use of cannabis as adolescents. He says more research is needed to understand why some people suffer from the condition after prolonged cannabis exposure and others do not. In addition, it is unclear why cannabis changes from a drug that has been known to ease nausea and vomiting, especially among patients undergoing chemotherapy, to causing nausea and vomiting in a subset of people. Many patients don’t realize that the syndrome is connected with their use of cannabis Meltzer says it is important for clinicians to advise those with frequent cannabinoid use or hyperemesis about the risks and subsequent disease burden. He says many patients don’t realize that the syndrome is connected with their use of cannabis. Physicians should explain that and advise patients on resources to help them quit, he says. The study, Cannabinoid Hyperemesis Syndrome is Associated with High Disease Burden: An Internet-based Survey, was published in the Annals of Emergency Medicine on Feb. 20, 2025. Andrew Meltzer explains more about the study in this GW video. -GW- To read the original article click here.

The post Daily Cannabis Use Linked to Public Health Burden appeared first on Amazing Health Advances.

Cannabis and Cars

The AHA! Team — Mon, 20 Jan 2025 06:40:50 +0000

Michael Greger M.D. FACLM via Nutrition Facts – Did traffic fatalities increase or decrease after cannabis legalization? Is cannabis-impaired driving a public health and safety concern? Well, the number of tickets for cannabis-impaired driving went up in Washington State after legalization, as did the proportion of drivers in fatal car crashes in Colorado who tested positive for marijuana use. But, in both cases, this “may simply reflect a general increase in marijuana use” overall. It doesn’t mean that cannabis is causing the crashes, as I discuss in my video The Effects of Marijuana on Car Accidents. There is a lot of evidence correlating marijuana use with car accidents, but who uses marijuana? Mostly young people and males. And guess who has a higher crash risk regardless of what they smoke? Young people and males. However, even taking that into account, it does seem that “roughly 20–30% of traffic crashes involving cannabis use occur because of the cannabis use.” But, to put that in perspective, that number is more like 85 percent when it comes to alcohol. Aren’t cannabis crashes low-velocity fender-benders from an impaired driver going like five miles an hour? “After a systematic review of the literature,” a compilation of studies “examining acute cannabis consumption and motor vehicle collisions…found a near doubling of the risk of a driver being involved in a motor vehicle collision resulting in serious injury or death.” So, that’s pretty serious, but alcohol is even worse. Cannabis may double or triple the risk of car crashes, but alcohol may multiply the risk 6- to 15-fold. The combination may be even worse—25 times the odds of a fatal car crash involvement when testing positive for both cannabis and alcohol. The “safety consequence of increased incidence of cannabis intoxication” when driving is listed as one of the “three primary reasons for concern about legalized cannabis….” Well, what happened in the U.S. states where marijuana was legalized? How much did traffic fatalities go up? They didn’t. In fact, they went down. What? “Why does legalizing medical marijuana reduce traffic fatalities?” Because of reduced alcohol consumption. It was found that “the legalization of medical marijuana is associated with reduced alcohol consumption, especially among young adults.” So, there was more drugged driving, but less drunk driving—and drunk driving is so much worse that fatalities went down overall. So, perhaps we’d also see less liver disease and less alcohol-induced brain damage, as cannabis substitutes for some of the alcohol use. Indeed, researchers argued that “cannabis was unlikely to produce as much harm as alcohol because, unlike alcohol, cannabis did not cause liver and other gastrointestinal diseases, it was not fatal in overdoses, it did not appear to be as neurotoxic as alcohol, and it was not as potent a cause of car crashes as alcohol.” “The health problems reported by cannabis dependent persons—e.g. bronchitis and impaired memory—are much less serious on average than those reported by persons who are alcohol dependent (e.g. delirium, liver disease, gastritis) but this does not mean that cannabis dependence is a minor problem.” When public health authorities bring that up, though, they may be criticized. In the 1940s and 1950s in the United States, for instance, after the repeal of Prohibition, we needed to warn people about the problems of heavy drinking, liver cirrhosis, and alcoholism, but some dismissed the concerns as if they were just “temperance propaganda.” We now see a similar situation, where the public health profession wants to educate people about the adverse health effects of cannabis but is dismissed as “reefer madness” hysterics. Still, it’s important to put these adverse health effects in perspective. How does the safety of cannabis stack up against alcohol and tobacco? According to the Centers for Disease Control and Prevention (CDC), “alcohol is linked to approximately 88,000 deaths per year,” whereas “there are no reported deaths due to cannabis.” (They’re from things like car accidents.) What’s more, they even go down when more people smoke pot because alcohol is so much worse. “With hindsight, we can clearly see the enormous problems that have been caused to many individuals and to society by tobacco and alcohol”—both legal drugs. “If asked to decide today which psychoactive drugs should be legal, cannabis (which rarely kills people) might well be judged as being comparatively benign” and may be much higher on the list. I have many other videos on cannabis if you’re interested. Check out the related posts below. I first released these videos in a webinar, and you can find them all on a digital download here. Key Takeaways After the legalization of marijuana, there was an increase in cannabis-impaired driving incidents and in the proportion of drivers in fatal crashes who tested positive for marijuana. However, this increase may reflect a general rise in marijuana use rather than directly causing more crashes. Although there is evidence correlating marijuana use with car accidents, it’s essential to note that young people and males, who are more likely to use marijuana, already have a higher risk of crashes. Cannabis use is estimated to be a factor in 20 to 30 percent of crashes involving its use, compared to about 85 percent for alcohol. A systematic review found that cannabis use nearly doubles the risk of serious injury or death in car crashes. However, alcohol poses a much greater risk, increasing the likelihood of crashes by 6 to 15 times. The risk is even higher when cannabis and alcohol are combined. Despite concerns, traffic fatalities did not increase in U.S. states where marijuana was legalized; they actually decreased. This reduction is attributed to a decrease in alcohol consumption, particularly among young adults, who may be substituting cannabis for alcohol. Cannabis is associated with fewer serious health problems compared to alcohol and tobacco. The CDC reports no direct deaths due to cannabis, whereas alcohol is linked to approximately 88,000 deaths per year. While cannabis dependence has health risks, they are generally less severe than those associated with alcohol dependence. To read the original article click here.

The post Cannabis and Cars appeared first on Amazing Health Advances.

Cannabis Exposure Linked to 1.3x Higher Risk of Unhealthy Pregnancy

The AHA! Team — Mon, 10 Jun 2024 08:35:02 +0000

University of Utah Health Newswise – In the past ten years, the percentage of Americans who use medical marijuana has more than doubled as state-level legalization becomes increasingly common. But despite its prevalence as a medication, the full health effects of cannabis remain unknown, especially for specific populations—such as pregnant people—that might be especially at risk of health complications. Now, in a large study of more than 9,000 pregnant people from across the U.S., researchers at University of Utah Health have found that cannabis exposure during pregnancy is associated with a composite measure of unhealthy pregnancy outcomes, especially low birth weight, and that higher exposure is associated with higher risks. Compared to most prior studies, this study was larger and measured cannabis exposure more accurately, which allowed researchers to distinguish the effects of cannabis itself from those caused by other correlated health conditions. The research published online on December 12 in JAMA. “Cannabis use is not safe,” says Robert Silver, M.D., professor of obstetrics and gynecology at U of U Health and last author on the study. “It increases the risk of pregnancy complications. If possible, you shouldn’t use cannabis during pregnancy.” The researchers were driven to answer this question in part by the contradictory answers that many people encounter when trying to learn about the health impacts of cannabis use. “There’s so much information out there—discussion and social media channels and on the Internet—about cannabis use and pregnancy,” explains Torri Metz, M.D., vice chair of research of obstetrics and gynecology at U of U Health and lead author on the study. “I think it’s hard for patients to understand what they should be worried about, if anything.” Uncovering new risks Indeed, some previous studies on the topic found no association between cannabis use and pregnancy complications. One hurdle facing such research, Metz says, is that there are “so many differences between baseline characteristics of people who use and don’t use cannabis during pregnancy. There’s different rates of anxiety and depression.” These differences can also impact pregnancy risks, which makes it challenging to figure out the consequences related specifically to cannabis use. The large study population, including participants from eight medical centers across the U.S., allowed the researchers to address this issue. Being able to compare pregnancy outcomes for so many participants, 610 of which had detectable levels of cannabis exposure, meant that the researchers could statistically untangle the impacts of cannabis use from many other factors, including pre-existing health conditions, nicotine exposure, and socioeconomic status. The scientists found that cannabis exposure was associated with a 1.3-fold increase in risk after the impacts of other factors were removed. Higher levels of cannabis exposure over the course of pregnancy were associated with higher risks. A distinguishing feature of the study was how the researchers measured cannabis exposure. While other studies had asked participants to report their own cannabis use (which has been shown to underestimate the actual rate of use by two or three times), the scientists measured the levels of a metabolic byproduct of cannabis in participants’ urine samples, which gave more accurate measurements of cannabis exposure. Open questions To gauge impacts on pregnancy, the researchers looked at an aggregate measure of negative health outcomes, including low birth weight, pregnancy-related high blood pressure, stillbirth, and medically indicated preterm birth. Of these, the association between cannabis use and low birth weight was the strongest. All of these conditions have been linked to reduced function of the placenta, which supplies the growing baby with oxygen and nutrients. While this type of study can’t determine why cannabis is associated with negative pregnancy outcomes, previous studies in non-human primates have found that long-term cannabis exposure can interfere with blood supply to the placenta. The correlation Metz and her colleagues observed suggests that cannabis may disrupt the human placenta in a similar way. Silver adds that the greater risk seen at higher levels of exposure is especially concerning given the high amount of THC found in newer cannabis products—products that were barely starting to become available from 2010 to 2014, when the study data was collected. The health impacts of these more concentrated products remain largely unknown. The researchers urge people who are considering using cannabis while pregnant to have an open conversation with their doctor. While pregnant people may turn to cannabis to alleviate nausea or anxiety, other remedies have been proven to be safe. “There are many, many reasons people use cannabis,” Silver says. “But there may be alternative therapies that can help mitigate the symptoms.” Silver emphasizes that continued research on the health impacts of cannabis is urgently needed so that patients can make informed decisions about their health. “As long as humans are interested in using this product,” he says, “we ought to assess health effects both good and bad, as accurately as we can, and provide that information for folks.” To read the original article click here.

The post Cannabis Exposure Linked to 1.3x Higher Risk of Unhealthy Pregnancy appeared first on Amazing Health Advances.

Marijuana and Schizophrenia?

The AHA! Team — Fri, 31 May 2024 05:31:56 +0000

Michael Greger M.D. FACLM via Nutrition Facts – The evidence linking cannabis use to psychotic disorders is considered strong enough to warrant a public health warning. “Even as proponents of [cannabis] legalization contend that smoked marijuana is a harmless natural substance that improves the quality of life, a growing body of evidence links it in a small but significant number of users to…the induction or aggravation of psychosis.” “Psychotic disorders are arguably the most serious of mental illnesses, the best known being schizophrenia.” “Schizophrenia, an illness that is characterized by delusions, hallucinations, and odd behavior, is among the top 10 leading causes of disability in the United States. It affects approximately 1% of the general population.” Can cannabis cause it? Schizophrenia… affects approximately 1% of the general population As I discuss in my video Does Marijuana Cause Schizophrenia?, over the last half-century, “nearly 2,000 studies have been published on this topic…and the pro-psychotic effects of cannabis have dominated media reporting about this drug. But how clear is the link?” Population studies have “consistently demonstrated a strong, positive, and dose-dependent association between cannabis use and the risk of psychotic disorders.” Indeed, studies have shown that the more cannabis people use, the more likely they are to be psychotic, as seen in a chart below and at 1:10 in my video. However, that doesn’t mean cannabis is the cause. It could just be a correlation or even a consequence of the disease. “The link between cannabis and psychosis is well established,” but it may be the case that patients with mental health problems self-medicate and “use cannabis to relieve their distress.” The link between cannabis and psychosis is well established… As you can see below and at 1:38 in my video, there isn’t only a link between cannabis and psychosis in snapshot-in-time cross-sectional studies, but in cohort studies as well, where people are followed over time. Research has shown that cannabis use often precedes psychosis, not the other way around. Now, it goes without saying that “the vast majority of people who use cannabis do not develop psychotic disorders such as schizophrenia, and many people diagnosed with such disorders have never used cannabis.” But, overall, these studies are considered to be “strong enough evidence to warrant a public health message that cannabis use can increase the risk of psychotic disorders.” There is another potential explanation: Even though cannabis use precedes schizophrenia, could it be that whichever genes drive schizophrenia also make it more likely you start smoking pot? The biggest strike against the cannabis-schizophrenia link is country-by-country ecological studies that don’t seem to show more disease in areas where there’s more use. And, overall, schizophrenia rates seem to have remained stable or even gone down worldwide since the 1960s, even though there’s been a big bump in cannabis use since then. If about 10 percent of schizophrenia cases are attributable to marijuana use and there’s been a fourfold increase in use, why hasn’t there been a 40 percent increase in the prevalence of schizophrenia? The problem with that argument is “there is little reliable evidence on the temporal [true] trends in the incidence of schizophrenia, so it is difficult to know whether this statement is true or not.” Perhaps it’s more of an issue with potency rather than just cannabis in general. Indeed, “the incidence of schizophrenia is higher in countries…where high-potency cannabis has taken over the market compared with countries…where more traditional forms of cannabis are smoked.” The bottom line is you don’t know until you put it to the test. You can’t just randomize kids to cannabis, but, in a way, Nature set up a natural experiment for us. There are genes that kids randomly get that can increase their likelihood of smoking pot. Do those kids then go on to have a higher risk of schizophrenia? Yes, research “findings strongly support” all of those population studies that suggest “cannabis plays a causal [cause-and-effect] role in the development of schizophrenia.” Okay, but by how much? Let’s break it down. Even if cannabis use doubles the risk, that would mean only going from a 7-in-1,000 chance of developing a psychosis to 14 in 1,000. So, going from a 1 in 140 chance to a 1 in 70 chance. It would be different if schizophrenia runs in your family, where a doubling of risk could mean going from a one-in-ten chance to one in five, but, on a population scale, it could take thousands of cannabis users quitting to prevent a single case of schizophrenia. So, from a public health standpoint, “addiction is a far more common problem.” Researchers “estimate that people who try cannabis are ninefold more likely to become addicted to it”—even though that itself is relatively rare—“than to develop psychosis in their lifetime.” I have an entire series of videos on cannabis, which I originally released in a webinar and downloadable digital DVD. Key Takeaways Although some proponents of cannabis legalization argue that marijuana is a “harmless natural substance that improves the quality of life,” it has been linked “in a small but significant number of users to…the induction or aggravation of psychosis.” Schizophrenia, a psychotic disorder characterized by hallucinations, odd behavior, and delusions, affects about 1 percent of the general population. Studies have found that the more cannabis people use, the more likely they are to be psychotic, but that could just be a correlation or even a consequence of the disease. Individuals with mental health problems may self-medicate and use cannabis to relieve distress, for example. Research has found that cannabis use often precedes psychosis, not the other way around. Overall, there appears to be “strong enough evidence to warrant a public health message that cannabis use can increase the risk of psychotic disorders.” There does not seem to be more disease in regions with greater cannabis use. Overall, schizophrenia rates appear to have remained stable or even declined worldwide since the 1960s, despite a large jump in cannabis use since then. Potency may be a bigger issue. In countries with higher potency cannabis, the incidence of schizophrenia is higher than in countries with “more traditional forms.” Some genes can increase our likelihood of using cannabis, and kids who randomly get them have been found to have a higher risk of schizophrenia. Research suggests that cannabis may have a cause-and-effect role in the development of that psychosis. Even if cannabis use doubles the risk, however, that would just mean a 1-in-70 chance of developing a psychosis without a family history of schizophrenia. From a public health standard, the far more common problem is addiction. To read the original article click here.

The post Marijuana and Schizophrenia? appeared first on Amazing Health Advances.

High-Strength Cannabis Linked to Addiction and Mental Health Problems

AHA Publisher — Wed, 27 Jul 2022 07:00:57 +0000

University of Bath via Newswise – As the strength or potency of cannabis products has increased internationally over the years, so have rates of people being treated for cannabis addiction, say the authors of a new study. Researchers from the Addiction and Mental Health Group at the University of Bath (UK) systematically analysed the relationship between the types of cannabis people use and their addiction and mental health problems. Their work draws on 20 studies involving almost 120,000 people. After alcohol and nicotine, cannabis is the most widely used drug globally. Latest estimates from the UK suggest that over the last year around one in five 16-24 year olds had used cannabis. Cannabis potency refers to the concentration of tetrahydrocannabinol (THC) in cannabis – the key psychoactive drug it contains. Recent studies from the same team at Bath have found that the concentration of THC in cannabis has increased significantly over time meaning that cannabis used today is typically much stronger than previously. The new study, published in The Lancet Psychiatry, suggests that people who use high potency cannabis are more likely to experience addiction than those using low potency products. It also suggests that people using high potency cannabis are more likely to experience a psychotic disorder, such as schizophrenia. These findings may help to explain why more people have received treatment for cannabis problems over recent years. Data from the European Monitoring Centre for Drugs and Drug Addiction show a 76% increase in people entering treatment for cannabis addiction in the past decade. Based on these new results, the authors argue that public health guidelines and policies to help make cannabis use safer should be encouraged. Lead author, Kat Petrilli from the University of Bath’s Department of Psychology explained: “Our systematic review found that people who use higher potency cannabis could be at increased risks of addiction as well as psychosis when compared to people who use cannabis products with lower potencies. “These results are important in the context of harm reduction which aims to minimise the negative consequences associated with drug use. While the safest level of use for cannabis is of course ‘no use’, it is important to acknowledge that a significant number of people across the world use cannabis regularly and to ensure they can make informed decisions that could reduce any possible harms associated with it.” The authors point out that strategies to make cannabis use safer could inform how the drug is regulated in the UK and internationally. Recreational cannabis use remains illegal in the UK, but cannabis products are now legally sold for recreational use in Canada, Uruguay, and parts of the USA. Several other countries appear set to follow this trend, including Germany. In the UK, the Liberal Democrats have argued that a legal regulated market could make cannabis use safer by enforcing a limit on the potency of cannabis products, and investing the revenue and savings from this into education and treatment for cannabis problems. Senior author, Dr Tom Freeman explained: “Our findings suggest that people who use cannabis could reduce their risk of harm by using lower potency products. In places where cannabis is legally sold, providing consumers with accurate information on product content and access to lower potency products could help people to use cannabis more safely.” Despite anecdotal evidence of links between cannabis and anxiety and depression, the authors note that the links between cannabis potency and other mental health problems are unclear. This research was funded by the Economic and Social Research Council. To read the original article click here.

The post High-Strength Cannabis Linked to Addiction and Mental Health Problems appeared first on Amazing Health Advances.

Cannabis Oil Effective in Treating Autism, Lab Trials Show

AHA Publisher — Thu, 06 Jan 2022 08:00:44 +0000

Naama Barak via Israel21c – In unique lab trials, researchers from Tel Aviv University alleviated symptoms of autism in animal models with medical cannabis oil, improving both behavioral and biochemical parameters of autism. Their novel research fills a notable gap in preclinical research. Medicinal cannabis is often administered to children and adolescents in clinical trials without knowing how cannabis affects biochemical processes or whether different types of cannabis oil can benefit different people. As described in Translational Psychiatry, the researchers administered cannabis oil to animals with a mutation in the Shank3 gene that is associated with about 1 percent of autism cases. “We saw that cannabis oil has a favorable effect on compulsive and anxious behaviors in model animals,” says Shani Poleg, the PhD student who led the research. “According to the prevailing theory, autism involves overarousal of the brain, which causes compulsive behavior. In the lab, in addition to the behavioral results, we saw a significant decrease in the concentration of the arousing neurotransmitter glutamate in the spinal fluid – which can explain the reduction in behavioral symptoms.” Which component of cannabis oil most effectively alleviated the symptoms of autism? Surprisingly, it was THC, which is responsible for the euphoric “high” associated with the use of cannabis. “Clinical trials testing cannabis treatments for autism usually involve strains containing very large amounts of CBD – due to this substance’s anti-inflammatory properties, and because it does not produce a sense of euphoria,” Poleg noted. “Moreover, the strains used for treating autism usually contain very little THC, due to apprehension regarding both the euphoria and possible long-term effects.” However, CBD alone had no impact on the behavior of the model animals. Treatment with cannabis oil containing THC but not CBD “produces equal or even better behavioral and biochemical effects.” “We observed significant improvement in behavioral tests following treatments with cannabis oil containing small amounts of THC and observed no long-term effects in cognitive or emotional tests conducted a month and a half after the treatment began,” Poleg concluded. To read the original article click here.

The post Cannabis Oil Effective in Treating Autism, Lab Trials Show appeared first on Amazing Health Advances.