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MRI Drugs Leave Toxic Heavy Metal Residue in the Brain

The AHA! Team — Wed, 27 Aug 2025 05:49:18 +0000

Lori Alton via NaturalHealth365 – MRIs help doctors see inside your body, but new findings have raised red flags. Medical experts want more research on health risks – especially how these metal-based contrast agents might build up in your body long after the scan. Many MRI procedures involve getting a contrast injection to improve the clarity of the images. The problem is that some patients with multiple MRIs report thinking problems afterward. These symptoms increasingly point to gadolinium, a metal used in contrast agents that may be more dangerous than we thought. New research shows it can stay in your body for years, even with healthy kidneys. What’s particularly concerning is that gadolinium might damage your cells and even your DNA. Scientific studies raise serious brain health concerns A study showed a correlation between intravenous gadolinium-based contrast agents and deposits of gadolinium found in neural tissues. Results were published online in Radiology, with lead author Robert McDonald, MD, PhD, Mayo Clinic, noting that some of the administered doses of contrast agent deposited in neural tissues were surprising. Patients who have undergone routine MRIs, such as Marcie Jacobs, later reported a loss of cognitive abilities. After having memory and other brain function issues following several years of routine MRIs for breast cancer detection, Ms. Jacobs ended up on disability. Also in the journal Radiology, Dr. Emanuel Kanal, University of Pittsburgh Medical Center, along with Michael Tweedle at Ohio State University, wrote that current studies “called into question” the “safety of at least some” of the agents. While the two did not call for an end to the use of these agents, they did call for increased caution in using these drugs. Are you being offered these MRI drugs? About a third of all MRIs in America still use gadolinium-based contrast agents, even as questions linger about their long-term safety. The FDA has tightened regulations rather than banning the most problematic agents outright – taking a different approach than European regulators who pulled Omniscan and Magnevist from their markets back in 2018. This safety debate isn’t new. Back in 2007, the U.S. Food and Drug Administration (FDA) first required warnings after research linked certain agents to nephrogenic systemic fibrosis, a serious condition causing tissue hardening, particularly in kidney patients who struggle to clear the metal from their bodies. Despite two FDA reviewers pushing for an outright ban on high-risk agents, the agency opted for stronger warnings instead. By 2010, they recommended against using Omniscan, Magnevist, and Optimark for patients with kidney problems. In 2018, warnings expanded to include gadolinium retention risks even for people with healthy kidneys. These days, doctors typically reach for newer macrocyclic agents, which hold their gadolinium more securely and seem less likely to release it into body tissues. However, the debate continues about whether these regulatory steps go far enough to protect patients. Gadolinium brain deposits spark ongoing safety debate Brain scans after certain contrast-enhanced MRIs show gadolinium sticking around – a discovery that’s raised eyebrows across medicine even without clear proof of harm. The findings haven’t definitively shown these metal deposits cause problems, but they’ve certainly got doctors thinking twice. GE Healthcare insists its research shows no evidence of harm from these brain deposits. Bayer has been working with outside researchers to get to the bottom of things. Both companies have settled their share of lawsuits, including some involving deaths. Back in 2010, Bayer reached a settlement with a California man who claimed Bayer’s product Magnevist gave him nephrogenic systemic fibrosis – a rare but serious condition. The health dangers continue to be a hot topic of debate. Research points in different directions – some studies raise red flags while others find no smoking gun. Doctors now find themselves weighing benefits against possible risks, especially when their patients already have kidney problems. The risk to MRI patients continues Doctors now check kidney function before giving patients contrast agents, but that might not solve the problem. We’re seeing gadolinium deposits showing up even in people with healthy kidneys, sometimes months or years after their MRIs. Researchers are worried about finding these metal traces in brain tissue at much higher levels than anyone thought possible. We don’t know yet how this might affect someone’s brain function or overall health over the long haul. The data simply isn’t there. This puts radiologists in a tough spot. These contrast agents help spot tumors, inflammation, and blood vessel problems that might otherwise go undetected. That’s incredibly valuable – but at what risk? Some hospitals have started switching to newer gadolinium compounds like the macrocyclic agents, which seem to hold onto their gadolinium better than older ones like Omniscan and Magnevist. Others are cutting doses to the bare minimum or skipping contrast altogether when possible. For patients needing multiple MRIs throughout their lives, the risk increases with each scan. Many are now asking for contrast-free procedures or looking for facilities that use the newer, possibly safer agents. Until we know more, the smart move seems to use the least risky contrast agents only when absolutely necessary. Meanwhile, researchers keep studying what happens to these metal deposits in the body over time. One thing’s for sure – we haven’t heard the last word on gadolinium safety. Editor’s note: Find out more about how to keep your kidney health strong, own the Fatty Liver Docu-Class package created by NaturalHealth365 Programs, that includes the Kidney Health Docu-Class. Sources for this article include: NIH.gov FDA.gov FDA.gov Current.com Auntminnie.com Propublica.org To read the original article click here.

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Protect Your Brain Health with These 4 Powerful Nutrients

The AHA! Team — Mon, 18 Aug 2025 05:23:26 +0000

Lori Alton via NaturalHealth365 – Perhaps you’ve heard people joke about having “senior moments,” those temporary lapses of memory that can leave you searching for a word — or a lost set of car keys. Perhaps you’ve even had a few yourself. Is this a sign of poor brain health? Unless they occur so frequently that they interfere with daily life, these little lapses are probably just a sign of normal age-related memory loss – and of the inevitable fact that your brain is getting smaller every year. Loss of brain mass can threaten cognition, memory, mood – even life itself Brain shrinkage, or loss of volume in the brain, is a normal part of aging. However, abnormally pronounced brain shrinkage puts you at risk for cognitive and movement disorders – and even stroke or premature death. Research shows that people with smaller brain volumes have a 96 percent increase in their risk of stroke – as well as a 58 percent increase in risk of death from all causes. Cardiovascular disease can be a major contributor to brain shrinkage. In one study, patients with coronary artery disease were found to have significantly smaller amounts of gray matter – with worse performances on cognitive tests. Diabetes, sleep disorders, stress, and obesity can all accelerate brain shrinkage as well. Lifestyle factors, such as a toxic diet, a lack of physical activity, smoking, and excessive drinking, can also speed the process. Neuroscientists say brain shrinkage can be slowed significantly with lifestyle changes. In addition to following a healthy diet and getting active, you can protect your brain by supplementing with the following four nutrients. Combine three different B-complex vitamins for brain health B-complex vitamins help to regulate homocysteine, an amino acid associated with heart disease. High levels of homocysteine cause brain shrinkage and dementia – especially when the body is deficient in B vitamins. Doctors say it’s important for aging people to maintain optimal B vitamin levels, especially those with high homocysteine levels. Three of the B-complex vitamins – vitamin B-12, vitamin B-9, and vitamin B-6 – are especially helpful in retaining brain volume. Vitamin B-12, or cobalamin, is found in fish, meat, and dairy. It is needed by the body to metabolize fatty acids, an important component of brain cells. People with B-12 deficiencies experience shrinkage at a rate that is 5 times faster than that of people with higher levels. Vitamin B-9, known as folate, occurs naturally in leafy vegetables, legumes, fruits, and organ meats such as beef liver. In one study, people with higher folate levels experienced slower rates of brain atrophy – as well as a longer period of time progressing from mild cognitive impairment to full-blown dementia. Vitamin B-6, or pyridoxine, is important in the production of neurotransmitters and the absorption of vitamin B-12. It occurs naturally in meat, fish, dairy, lentils, and brown rice. In a controlled trial published in the scientific journal PLoS One, adults over 70 with mild cognitive impairment were given 800 mcg of folate, 500 mcg of vitamin B-12, and 20 mg of vitamin B-6 daily for two years and experienced brain shrinkage at a rate of 30 percent slower than the control group. For participants with elevated homocysteine at the beginning of the study, results were even more dramatic — they slowed their brain shrinkage rate by 53 percent. Are high-fat diets bad for the brain? Healthy fats – such as the omega-3 fatty acids in fish oils and nut oils – are a major part of brain cell membranes, and optimal levels can play a key role in protecting your brain. Higher levels of the omega-3 components known as DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid) are associated with larger brain volumes. When DHA and EPA levels drop, age-related cognitive deficits worsen. Major depressive disorder and bipolar disorder are both associated with abnormal distributions in the brain of fatty acids. People with Alzheimer’s disease also show low levels of fatty acids. Omega-3s protect against over-excitation – a primary cause of age-related brain cell damage – while decreasing inflammation and protecting against damage from stress. Pomegranate juice sharpens memory and improves cognition Pomegranates are rich in anti-inflammatory, antioxidant, and neuroprotective plant-based compounds called polyphenols. This flavorful juice can help reduce overall fat content in obese people, help regulate blood sugar, and fight inflammation – “win/win” scenarios in the fight against brain shrinkage. And researchers have found that a mere 8 ounces of pomegranate juice a day can improve cognition and memory. Compound from grapes and berries may enlarge memory center Resveratrol is a phenol in red grapes, red wine, and darkly pigmented fruits such as blueberries. Studies showed that resveratrol increased volume in the hippocampus – the part of the brain associated with memory. It also helped protect against oxidative damage that leads to brain cell death and reduced injury to brain endothelial cells with high-fat diets. In a 2014 study published in the Journal of Neuroscience, adults who were overweight but otherwise healthy were given 200 mg of resveratrol daily for 26 weeks. Researchers found that resveratrol improved connections between the hippocampus and frontal sections of the brain and served to increase memory performance. They noted resveratrol’s potential as a novel strategy to maintain brain health during aging. As baby boomers round the corner into advanced age, avoiding loss of brain volume becomes a must for optimal health. Never underestimate the power of good (organic) nutrition and healthy lifestyle changes. Editor’s note: Discover the best ways to avoid and even REVERSE the signs of dementia, own the Alzheimer’s and Dementia Summit created by NaturalHealth365 Programs. Sources for this article include: NIH.gov Lifeextension.com NIH.gov NIH.gov To read the original article click here.

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Summer Brain Fog? It Could Be Your Gut — Here’s What Scripture & Science Say About It

The AHA! Team — Wed, 28 May 2025 05:14:57 +0000

Dr. Don Colbert – If you find yourself feeling mentally sluggish during the summer months—struggling with memory, focus, or motivation—you’re not alone. Many of my patients describe what they call “summer brain fog.” And while you might blame it on the heat or disrupted routines, there’s often a deeper root: your gut. In this article, I want to unpack the fascinating link between gut health and brain function, and why healing your gut might be the most effective way to sharpen your mind—especially this time of year. We’ll also look at what science has to say, and how Scripture reinforces the importance of caring for our bodies with wisdom and intentionality. The Gut-Brain Connection: More Than a Feeling The gut and brain are connected by a complex network of nerves, biochemicals, and messenger systems known as the gut-brain axis. This communicationToxic Summer: Hidden Chemicals in Sunscreen, Swimsuits, and Bug Spray — And What God Says About Stewarding Your Body highway allows your digestive system to send and receive signals to and from your brain—often influencing mood, focus, memory, and even sleep. Here’s what we know from science: The gut produces over 90% of the body’s serotonin, a neurotransmitter crucial for mood regulation. An imbalance in the gut microbiome—such as an overgrowth of bad bacteria or yeast—can trigger inflammation, which can cross the blood-brain barrier and contribute to brain fog, anxiety, and fatigue. Studies show that gut dysbiosis (imbalanced bacteria) is associated with cognitive decline and poor memory. When the gut is struggling, the brain often suffers quietly until symptoms like fatigue, poor concentration, or forgetfulness emerge. Why Summer Makes It Worse There are several seasonal habits that may quietly sabotage gut health during the summer: 1. Processed Summer Treats Ice cream, BBQ sauces loaded with sugar, soda, and artificial dyes—these common indulgences can feed harmful gut bacteria and promote systemic inflammation. 2. Travel & Disruption of Routine Whether it’s international travel or a simple road trip, your digestion can be thrown off by irregular meals, different water sources, or unfamiliar foods. 3. Alcohol & Dehydration Increased alcohol intake and reduced hydration in the heat can irritate the gut lining and impair healthy digestion. 4. Sleep Disturbance Longer days and more activity can interfere with restful sleep, which your gut (and brain) need for repair and detox. What You Can Do to Restore Clarity If you want to reclaim your mental edge this summer, healing your gut is an excellent place to start. Here are a few simple yet powerful steps: 1. Cut the Sugar and Processed Foods Sugar feeds the wrong bacteria. Swap sugary snacks for high-fiber fruits like berries, which also support digestion and reduce inflammation. 2. Rebuild with Probiotics and Fiber Adding a quality probiotic and a soluble fiber supplement helps repopulate good bacteria and keep your gut regular. I often recommend Zone Biotics Probiotic and Fiber Zone from Divine Health. 3. Consider Advanced Gut Support For those needing more comprehensive care, Biotic Zone Probiotic is an advanced formula that combines powerful probiotics and prebiotics to promote digestive balance, reduce bloating, and support brain-gut communication. 4. Support the Gut Lining L-glutamine, aloe vera, and collagen can help repair a leaky gut. You can find these in many gut repair powders or take them separately. Explore our detox and cleanse supplements for comprehensive support. 5. Hydrate Intentionally Drink filtered water consistently throughout the day. Add sea salt or electrolytes to help absorption, especially if you’re sweating more than usual. 6. Focus on Anti-Inflammatory Foods Include foods like leafy greens, turmeric, wild salmon, and extra virgin olive oil. These nourish the brain and gut while reducing inflammation. Gut-Healing Foods That Also Fuel Mental Clarity Your food choices play a pivotal role in gut health—and by extension, brain function. Here are some of the best whole foods to incorporate into your daily routine: 1. Fermented Foods Kimchi, sauerkraut, kefir, and unsweetened yogurt are rich in probiotics that help replenish good bacteria in your gut. 2. Prebiotic-Rich Foods Foods like garlic, onions, leeks, asparagus, and green bananas feed the good bacteria and support a thriving microbiome. 3. Omega-3 Rich Foods Wild-caught salmon, sardines, flaxseeds, and chia seeds help reduce inflammation and support the brain-gut connection. 4. Polyphenol-Packed Plants Blueberries, pomegranate, spinach, and dark chocolate (70%+ cacao) provide antioxidants that protect both the brain and gut lining. 5. Bone Broth Loaded with collagen and amino acids like glutamine, bone broth helps seal and heal the gut lining. 6. Clean Proteins Organic pasture-raised poultry, wild-caught fish, and grass-fed beef provide essential nutrients for cellular repair and neurotransmitter production. These foods are a foundational part of the preventative and holistic approach I recommend—and they nourish more than just your body. They create the internal environment needed for peace, energy, and mental clarity. What Scripture Reminds Us About the Body Scripture reminds us that our bodies are a gift from God, and we are called to steward them well: “Do you not know that your bodies are temples of the Holy Spirit, who is in you, whom you have received from God?” — 1 Corinthians 6:19 Caring for your body—including your gut—isn’t just about physical health. It’s about clarity, energy, and the ability to serve others and fulfill your purpose with excellence. Sometimes the greatest clarity doesn’t come from another coffee or pushing through fatigue. It comes from healing the internal systems God designed to work together in harmony. 🛒 Ready to Support Your Gut? Explore Dr. Colbert’s Top Gut Health Supplements: 👉 Zone Biotics Probiotic 👉 Fiber Zone 👉 Biotic Zone Probiotic 👉 Detox & Cleanse Collection Final Thoughts Summer brain fog isn’t something you have to live with or push through. By supporting your gut, you support your brain—and ultimately your quality of life. From a scientific perspective, gut health is one of the most powerful levers for cognitive and emotional wellness. And from a spiritual perspective, it’s a meaningful way to honor the temple God entrusted to us. Until next time, stay sharp, stay healthy, and stay grounded in grace. To your health, Dr. Don Colbert, MD To read the original article click here.

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Brain Imaging + Virtual Reality Shows Promise for Effectively Managing Cancer Pain

The AHA! Team — Wed, 14 May 2025 05:38:10 +0000

Roswell Park Comprehensive Cancer Center via Newswise – Roswell Park-led study takes a significant step toward relief without opioids Highlights Advanced brain imaging gauges pain objectively Virtual-reality relaxation program found clinically effective for pain relief More than 75% of patients who used VR reported a decrease in pain A clinical research study Newswise — BUFFALO, N.Y. — A clinical research study led by Roswell Park Comprehensive Cancer Center has identified a way to objectively measure pain in cancer patients and treat it effectively without opioids. Published in Scientific Reports, the study advances the goal of better managing cancer pain using a non-invasive brain imaging technology and a non-drug treatment that incorporates virtual reality (VR). The project was led by principal investigator Somayeh Besharat Shafiei, PhD, Assistant Professor of Oncology in Roswell Park’s Department of Urology, and co-investigator Oscar de Leon-Casasola, MD, Chief of Pain Medicine at Roswell Park, and included team members from Roswell Park and the University of Guelph in Ontario. A new strategy They propose and assess a new strategy combining brain imaging with the use of functional near-infrared spectroscopy (fNIRS) — a way to gauge the severity of pain using a head cap fitted with optical sensors — and the use of virtual reality to provide pain relief. All participants wore fNIRS head caps to record brain activity by measuring changes in blood oxygenation and deoxygenation. This made it possible for the researchers to identify brain-based biomarkers that distinguish between three levels of pain: no/mild, moderate and severe. Some participants also used VR headsets equipped with software that allowed them to explore realistic underwater scenes. The researchers believe VR may influence a person’s perception of pain by modulating pain-related neural circuits in the regions of the brain. The study enrolled 147 participants, including: 13 healthy patients, who wore fNIRS head caps for 10 minutes 93 cancer patients experiencing pain, who wore fNIRS head caps for 10 minutes 41 cancer patients experiencing pain, who wore fNIRS head caps and VR headsets for a total of 29 minutes —10 minutes before VR, nine minutes during VR and 10 minutes after VR Of the pain-afflicted cancer patients who used the VR program, more than 75% self-reported a decrease in pain — indicating a noticeable improvement well beyond the clinically relevant threshold of 30%. Results of the brain imaging suggest that VR has an effect on both the cognitive and emotional aspects of pain. “This study signals a new era in precision medicine where neuroimaging and digital therapeutics revolutionize pain assessment and treatment,” says Dr. Besharat Shafiei, first author of the study, who notes that an estimated 60-80% of cancer pain is not properly managed. “This combination therapy could reshape clinical pain management protocols, reduce reliance on opioids, and improve the quality of life for millions of cancer patients worldwide.” To read the original article click here.

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Ingredient In Coffee Improves Your Memory (It’s NOT Caffeine)

The AHA! Team — Fri, 02 May 2025 05:34:35 +0000

Al Sears, MD, CNS – If you think the caffeine in your morning cup o’ joe is solely responsible for its coveted brain-boosting benefits, you’re not alone. After all, caffeine is a key reason why 81% of Americans get their day going by drinking at least two cups of coffee every day.1 And studies prove this naturally occurring herbal stimulant can improve both short-term and long-term memory2,3 increase alertness and reduce fatigue,4 and enhance cognition.5 But coffee has a special helper that most people don’t know about. I’m talking about a little-known compound called trigonelline, a unique form of vitamin B3 (niacin). Trigonelline, which is also found in fenugreek seeds, Japanese radishes, and hemp seeds, has been shown to:6 Increase spatial learning and memory Support nervous system development Enhance mitochondrial function and Increase key neurotransmitters in the hippocampus of the brain But its key brain benefit is that it suppresses neuroinflammation. As a regular reader, you know how dangerous inflammation is, and how it’s often a key factor in chronic diseases, especially in the brain. You see, breakthrough research confirms that amyloid plaques – the misfolded proteins that are a key symptom of Alzheimer’s disease – are caused by a breakdown of the immune system, triggered by widespread inflamm-aging. Amyloid plaques prevent neurons from working properly. When your brain is inflamed and your immune system can no longer clear away these rogue proteins, they cluster together and gum up the signaling networks between your neurons. Eventually, it leads to memory loss and confusion. At the same time, inflammation squeezes the blood vessels in your brain, restricting oxygen supply, causing cell damage, loss of brain tissue, and cell death. A new study, aimed at investigating the therapeutic potential of trigonelline, revealed it may effectively treat Alzheimer’s, Parkinson’s, epilepsy, and depression7 by preventing oxidative stress.8 Oxidative stress can feel like brain fog, chronic fatigue, or a headache. It can also result in memory loss, infections, and serve as a catalyst for inflammatory diseases.9 Preventing oxidative stress helps control your body’s inflammatory response. The implications of these studies for trigonelline as a neuroenhancer, and for coffee lovers are huge. Coffee lovers can rejoice in knowing there is truly something special about their cup of joe other caffeinated beverages can’t match. Get The Most Out Of Your Cup Of Coffee Drinking a cup or two of coffee is the best way to increase trigonelline levels. Here’s what I recommend: Choose Arabica coffee. While both Arabica and robusta coffee beans contain this brain-saving enzyme, concentrations are twice as high in Arabica. Look for certified organic beans. Not only are they higher in antioxidants, they don’t use any synthetic chemicals or fertilizers. I also suggest looking for “Fairtrade” on the label. This protects traditional small coffee farmers. Drink it fresh. Grind your coffee at the time you wish to drink it. This maximizes the flavor and prevents oxidation. Coffee’s healing properties are best when brewed fresh. Drink it black. The best benefits of coffee are delivered in its purest state. Adding dairy products and sweeteners may alter the taste, but it will also diminish the rewards. If you’re not a fan of coffee, you can supplement with fenugreek capsules. I suggest taking 500 mg a day. To Your Good Health, Al Sears, MD, CNS References: Buchholz K. “How many cups of coffee do Americans drink each day?” January 2023. https://www.statista.com/chart/19524/cups-of-coffee-drunk-by-americans-per-day/ Accessed on November 30, 2023. Sherman S, et al. “Caffeine Enhances Memory Performance in Young Adults during Their Non-optimal Time of Day.” Front Psychol. 2016; 7: 1764. Borota D, et al. “Post-study caffeine administration enhances memory consolidation in humans.” Nat Neurosci. 2014 Feb;17(2):201-3. Nehlig, A. “Is caffeine a cognitive enhancer? J Alzheimer’s Dis. 2010;20(S1):S85-S94. Zhang B, et al. “Cognition and brain activation in response to various doses of caffeine: a near-infrared spectroscopy study.” Front Psychol. 2020 July 3;1393. Aktar S, et al. “Transcriptomics and biochemical evidence of trigonelline ameliorating learning and memory decline in the senescence-accelerated mouse prone 8 (SAMP8) model by suppressing proinflammatory cytokines and elevating neurotransmitter release.” GeroScience. 2023. Zia S, et al. “Unlocking therapeutic potential of trigonelline through molecular docking as a promising approach for treating diverse neurological disorders.” Metabolic Brain Disease. 2023. Chowdhury A, et al. “Trigonelline insulates against oxidative stress, proinflammatory cytokines and restores BDNF levels in lipopolysaccharide induced cognitive impairment in adult mice.” Metab Brain Dis. 2018;33(3):681-691. Pizzino G, et al. “Oxidative stress: Harms and benefits for human health.” Oxid Med Cell Longev. 2017:8416763. To read the original article click here.

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Dementia Surging Among Younger Adults at Unprecedented Rates, Study Reveals

The AHA! Team — Fri, 04 Apr 2025 05:04:20 +0000

News Staff via NaturalHealth365 – Young minds are deteriorating faster than anticipated, with early-onset dementia diagnoses rising at an alarming rate among young adults. This growing trend is profoundly affecting working-age individuals and their families. In fact, recent findings published in Neurology Journals highlight the increasing prevalence and incidence of early-onset dementia, shedding light on the significant mental health challenges faced by those under 65. Beyond the individuals themselves, dementia takes a toll on their loved ones and society as a whole. As more young and middle-aged adults are diagnosed, the burden on our healthcare system – and its associated costs – continues to escalate. The growing global crisis of early-onset dementia Finnish researchers recently analyzed the prevalence and incidence of early-onset dementia – defined as dementia occurring before age 65 – over a span of just over a decade. Their findings revealed that incidence rates were higher than previously reported and showed a progressive increase throughout the 11-year study period. However, it’s important to note that the data was limited to two regions in Finland: Northern Savonia in Eastern Finland and Northern Ostrobothnia in the north. Further insights were provided by a systematic review published in JAMA Network Further insights were provided by a systematic review published in JAMA Network, which analyzed 95 studies on early-onset dementia. This global review found that the standardized prevalence of early-onset dementia averaged 119 cases per 100,000 individuals aged 30 to 64. Alarmingly, the incidence among individuals aged 30 to 34 showed an increase of 1.1 cases per 100,000. These findings show that early-onset dementia is not confined to Finland or specific regions but represents a growing global health challenge. Natural solutions for maintaining cognitive performance You can take steps to proactively defend against the development of early-onset dementia. A diet highlighted by Mediterranean foods, meaning wild fish, organic olives, nuts, and leafy greens, is beneficial to brain health. Foods rich in antioxidants, such as organic dark chocolate, bell peppers, berries, and tomatoes, also help prevent dementia. Moreover, fish, walnuts, and other foods with omega-3 fatty acids improve brain functionality, helping to slow the progression of dementia and cognitive decline. Like other body sites, the brain needs sufficient blood flow to function at peak performance. Engage in strength training and aerobic exercises to boost blood flow to your brain. Mental stimulation also helps ward off dementia. Continue your quest for knowledge through lifelong learning. If you struggle to remember things, play cognitive training games or enroll in a class or two at your local community college. Even socialization plays a role in keeping the mind sharp and your spirit high. Engage in social activities with neighbors, family, and friends. If you are isolated, consider volunteering or joining others for Bingo Night or other local events that provide much-needed mental stimulation. Minimize the stress in your life, and you’ll find that your mind isn’t nearly as crowded. You’ll think more clearly with sufficient sleep. Engage in daily meditation for 10 minutes and practice mindfulness exercises to keep your mind sharp. Though study results are mixed, there is some evidence that herbal supplements such as turmeric (curcumin) and ginkgo biloba promote cognitive function. If you drink alcohol, limit your intake, as alcohol is a subtle poison that kills brain cells. Editor’s note: Discover the best strategies to avoid and reverse the signs of dementia, own the Alzheimer’s and Dementia Summit created by NaturalHealth365 Programs. Sources for this article include: Neurology.org NIH.gov Studyfinds.org To read the original article click here.

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Excessive Abdominal Fat Linked to “Shocking” Problem for the Brain

The AHA! Team — Fri, 14 Feb 2025 06:11:46 +0000

Sara Middleton via NaturalHealth365 – Obesity is not an unusual phenomenon in the Western world. For example, in the United States, you’re actually MORE likely to meet a person carrying around extra body fat than not, with about 75% of adult males, 60% of adult females, and 30% of children falling into the overweight or obese category. These figures are shocking, to say the least. But perhaps more alarming is recent research revealing how excess body fat impacts the brain. Studies have found that higher body mass index (BMI) is associated with changes in brain structure and function across all ages. In children, higher BMI correlates with reduced working memory performance and smaller gray matter volume in areas related to memory and cognitive control. Similarly, research on adults shows that higher BMI and waist-to-hip ratios are linked to overall gray matter atrophy, with specific reductions in regions tied to cognition and reward. In short, carrying extra body fat doesn’t just affect physical health – it may be shrinking the brain. Research reveals the shocking association between obesity and brain health The researchers of a study published in Neurology analyzed brain MRI imaging of 9,652 people, 19% of whom were obese or overweight (they measured body mass index, waist-to-hip ratio (WHR), and total fat mass to help determine this). It turns out that having a high BMI plus a high waist-to-hip ratio (indicating a greater amount of abdominal fat) makes you more likely to have lower gray matter volume in your brain. If you’re wondering, gray matter contains a majority of the nerve cells in your brain and is important for everything from self-control to physical movement. Loss of gray matter and overall brain shrinkage are associated with things like dementia and other cognitive health problems. Incredibly, these changes remained even after the researchers adjusted for other factors known to affect brain mass, including age, physical activity levels, high blood pressure, and smoking. They conclude: “The combination of heightened BMI and WHR may be an important risk factor for gray matter atrophy.” While the researchers acknowledge that they have a bit of the “chicken or the egg” conundrum – ‘Did the brain shrinkage lead to obesity or did obesity lead to brain shrinkage?’ – we certainly think it’s reasonable to assume the latter, considering that we know so many other ways being overweight can impact brain health and mental function. The connection between BMI, brain structure, and cognitive performance in children In even more recent research, scientists explored the effect of obesity on children’s brain health. They found that higher BMI was associated with poorer working memory performance and smaller gray matter volumes in key brain areas, including the left superior frontal gyrus, dorsal anterior cingulate cortex, and medial orbital frontal cortex. Children with higher BMI also showed weaker activation in the caudate, amygdala, and other brain regions involved in memory tasks. Specifically, the dysfunction in the caudate appeared to mediate the relationship between higher BMI and lower working memory accuracy. This study on children supports the growing body of evidence that higher body fat not only affects physical health but also impacts brain function. Interestingly, these brain changes were linked to poorer memory abilities, suggesting that obesity in childhood may have long-term implications for cognitive development. Other surprising ways abdominal fat impacts your brain function Having excess body fat is linked with an increased risk for serious health conditions, including diabetes, arthritis, cancer, and heart disease. But it also can hurt your head, too! For instance, being overweight has been shown to: Lead to a “tolerance” to sugary and fried foods (much like people who use drugs become tolerant to their drug of choice and need more and more of it to get the same high-inducing effects), which is believed to be a major driver of food addiction Decrease the size of a part of the brain called the orbitofrontal cortex (necessary for controlling impulsivity), which can lead to uncontrolled eating Impair memory, likely due to hormones released by fat cells that trigger inflammation and damage tissues The takeaway here is simple and direct: maintaining lean body weight is good for you from head to toe. So, commit to a balanced whole foods (organic) diet, stay physically active – regularly, and do everything you can to reduce the level of (chronic) stress you experience. Remember, you deserve to be happy, healthy, and energetic – all the days of your life. Sources for this article include: NIH.gov Neurology.org Sciencedaily.com Livescience.com To read the original article click here.

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Bali Secret Grows New Brain Cells

The AHA! Team — Mon, 10 Feb 2025 06:32:15 +0000

Al Sears, MD, CNS – When I was in Bali, I learned that elephants – which are well known for their long and impressive memories – go to great lengths to seek out gotu kola leaves. It’s one of their favorite foods. Could this plant be the reason why elephants never forget? Who knows? What we do know is that research proves gotu kola can enhance your brain power. Let me explain… For decades, scientists believed that the adult human brain couldn’t grow new brain cells. They thought we were born with all the brain cells we’ll ever have – and that when they were gone, they were gone for good. They thought we were born with all the brain cells we’ll ever have However, a breakthrough study by researchers at Princeton University proved the opposite. That study, published in the prestigious Journal of Science, revealed the continuous growth of new brain cells in adult macaque monkeys. Then, a follow-up study published in the journal Cell found that humans also produce new neurons. And that – even in old age – your brain still produces around 700 new neurons a day.[i] In other words, despite what “medical experts” may tell you, your memory and cognitive performance don’t have to decline. In fact, they can actually improve as you age. And one of the best ways to boost your brain performance is with gotu kola, or Centella asiatica. Research shows it can revitalize your brain and nervous system and help you feel sharp and alert as it recharges your memory. Research shows it can revitalize your brain and nervous system In a number of studies, gotu kola enhanced memory performance, problem-solving abilities, intelligence, and mental energy.[ii] A landmark study published in the Journal of Pharmacy and Pharmacology found that gotu kola stimulates the growth of brain cells…[iii] While additional studies proved that gotu kola: [iv],[v],[vi],[vii] Improves cognitive function – even in cognitively impaired older adults Doubles how quickly and accurately you process information Increases problem-solving skills up to 45% Improves reading skills up to 29% Significantly boosts your attention span Increases concentration Further studies also give us lots of evidence that gotu kola is a powerful antioxidant and brain protector, as well as a nerve growth factor. Studies show it may also help stop plaque formation in Alzheimer’s disease and prevent dopamine neurotoxicity in Parkinson’s.[viii],[ix] I’ve recommended gotu kola for years as a way to treat stroke victims suffering from stroke-related dementia. A recent study backs up what I learned from traditional healers… According to this study from Indonesia, where gotu kola is used commonly in both traditional and mainstream medicine, concluded that therapy with an extract of the herb at 750 mg per day for six weeks was “effective in improving cognitive impairment after stroke.” The extract is called TTFCA, which stands for triterpenic fraction of Centella asiatica. This contains gotu kola’s most potent components. And it has shown special strength in improving memory.[x] Other studies have shown gotu kola is highly effective at preventing strokes in the first place – by promoting healthy veins and combatting high blood pressure. TTFCA improves the dilatation of blood vessels, which decreases blood pressure and improves blood flow throughout your body – from the largest veins to the tiniest of capillaries.[xi] When choosing a gotu kola supplement, look for one with more of the active components. Choose one that is standardized to the asiaticosides or asiatic acid. 3 Ways You Can Improve Your Memory with Gotu Kola I recommend my patients use gotu kola in three ways. As an extract. Take 10 to 20 ml per day. As a supplement. When choosing a gotu kola supplement, look for one with more of the active components. Select one that is standardized to the asiaticosides or asiatic acid. I recommend taking 300 mg a day. As a dried herb. One of my favorite ways to use gotu kola is by making a cup of tea. Here’s how: Measure 1 to 2 teaspoons (about 6 to 8 grams) of dried gotu kola into a cup. Cover with boiling water and allow to steep for 15 minutes. Strain, then sweeten with organic honey. Enjoy three cups a day. [i] Spalding K, et al. “Dynamics of hippocampal neurogenesis in adult humans.” Cell. 2013 Jun 6; 153(6):1219–1227. [ii] Prakash A, Kumar A. “Mitoprotective effect of Centella asiatica against aluminum-induced neurotoxicity in rats: possible relevance to its anti-oxidant and anti-apoptosis mechanism.” Neurol Sci. 2013 Aug;34(8):1403-9. [iii] Soumyanath A, et al. “Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro.” J Pharmacy Pharmacol. 2005;57(9):1221–1229. [iv] Shinomol GK, et al. “Exploring the role of ‘Brahmi’ (Bacopa monnieri and Centella asiatica) in brain function and therapy.” Recent Pat Endocr Metab Immune Drug Discov. 2011;5(1):51-57. [v] Xu Y, et al. “Gotu kola (Centella Asiatica) extract enhances phosphorylation of cyclic AMP response element binding protein in neuroblastoma cells expressing amyloid beta peptide.” J Alzheimers Dis. 2008 Apr;13(3):341-9. [vi] Tiwari S, et al. “Effect of Centella asiatica on mild cognitive impairment (MCI) and other common age-related clinical problems.” Dig J Nanomater Bio. 2008;3:215–220. [vii] Wattanathorn J, et al. “Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica.” J Ethnopharmacol. 2008;116(2):325-332. [viii] Orhan I. “Centella asiatica (L.) Urban: From traditional medicine to modern medicine with neuroprotective potential.” eCAM. 2012;2012:946259. [ix] Xu Y, et al. “Gotu Kola (Centella Asiatica) extract enhances phosphorylation of cyclic AMP response element binding protein in neuroblastoma cells expressing amyloid beta peptide.” J Alzheimers Dis. 2008 Apr; 13(3):341-9. [x] Farhana KM, Malueka RG, et al. “Effectiveness of gotu kola extract 750 mg and 1000 mg compared with folic acid 3 mg in improving vascular cognitive impairment after stroke.” eCAM. 2016: 2795915. [xi] Incandela L, et al. “Total triterpenic fraction of Centella asiatica in chronic venous insufficiency and in high-perfusion microangiopathy.” Angiology. 2001 Oct.;52 Suppl 2:S9-13. To read the original article click here.

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Glyphosate Exposure Linked to Lasting Brain Inflammation

The AHA! Team — Mon, 20 Jan 2025 06:04:19 +0000

Arizona State University via News-Medical – The human brain is an incredibly adaptable organ, often able to heal itself even from significant trauma. The human brain is an incredibly adaptable organ, often able to heal itself even from significant trauma. Yet for the first time, new research shows even brief contact with a common herbicide can cause lasting damage to the brain, which may persist long after direct exposure ends. In a groundbreaking new study, Arizona State University researcher Ramon Velazquez and his colleagues at the Translational Genomics Research Institute (TGen), part of City of Hope, demonstrate that mice exposed to the herbicide glyphosate develop significant brain inflammation, which is associated with neurodegenerative disease. The findings suggest the brain may be much more susceptible to the damaging effects of the herbicide than previously thought. Glyphosate is one of the most pervasive herbicides used in the U.S. and worldwide. The research, which appears today in the Journal of Neuroinflammation, identifies an association between glyphosate exposure in mice and symptoms of neuroinflammation, as well as accelerated Alzheimer’s disease-like pathology. This study tracks both the presence and impact of glyphosate’s byproducts in the brain long after exposure ends, showing an array of persistent, damaging effects on brain health. The research, appeared in the Journal of Neuroinflammation Glyphosate exposure in mice also resulted in premature death and anxiety-like behaviors, which replicates findings by others examining glyphosate exposure in rodents. Further, the scientists discovered these symptoms persisted even after a 6-month recovery period during which exposure was discontinued. Additionally, the investigation demonstrated that a byproduct of glyphosate – aminomethylphosphonic acid – accumulated in brain tissue, raising serious concerns about the chemical’s safety for human populations. “Our work contributes to the growing literature highlighting the brain’s vulnerability to glyphosate. Given the increasing incidence of cognitive decline in the aging population, particularly in rural communities where exposure to glyphosate is more common due to large-scale farming, there is an urgent need for more basic research on the effects of this herbicide.” Ramon Velazquez, researcher, Arizona State University Velazquez is a researcher with the ASU-Banner Neurodegenerative Disease Research Center at the ASU Biodesign Institute and an assistant professor with the School of Life Sciences. He is joined by first author Samantha K. Bartholomew, a PhD candidate in the Velazquez Lab, other ASU colleagues, and co-senior author Patrick Pirrotte, associate professor with the Translational Genomics Research Institute (TGen) and researcher with the City of Hope Comprehensive Cancer Center in California. According to the Centers for Disease Research, farm laborers, landscape workers, and others employed in agriculture are more likely to be exposed to glyphosate through inhalation or skin contact. Additionally, the new findings suggest that ingestion of glyphosate residues on foods sprayed with the herbicide potentially poses a health hazard. Most people living in the U.S. have been exposed to glyphosate during their lifetime. “My hope is that our work drives further investigation into the effects of glyphosate exposure, which may lead to a reexamination of its long-term safety and perhaps spark discussion about other prevalent toxins in our environment that may affect the brain,” Bartholomew says. The team’s findings build on earlier ASU research that demonstrates a link between glyphosate exposure and a heightened risk for neurodegenerative disorders. The previous study showed that glyphosate crosses the blood-brain barrier, a protective layer that typically prevents potentially harmful substances from entering the brain. Once glyphosate crosses this barrier, it can interact with brain tissue and appears to contribute to neuroinflammation and other harmful effects on neural function. The EPA considers certain levels of glyphosate safe for human exposure, asserting that the chemical is minimally absorbed into the body and is primarily excreted unchanged. However, recent studies, including this one, indicate that glyphosate, and its major metabolite aminomethylphosphonic acid, can persist in the body and accumulate in brain tissue over time, raising questions about existing safety thresholds and whether glyphosate use is safe at all. Herbicide may attack more than weeds Glyphosate is the world’s most heavily applied herbicide, used on crops including corn, soybeans, sugar beets, alfalfa, cotton and wheat. Since the introduction of glyphosate-tolerant crops (genetically engineered to be sprayed with glyphosate without dying) in 1996, glyphosate usage has surged, with applications predominately in agricultural settings. The U.S. Geological Survey notes approximately 300 million pounds of glyphosate are used annually in the United States alone. Although glyphosate levels are regulated on foods imported into the United States, enforcement and specific limits can vary. Due to its widespread use, the chemical is found throughout the food chain. It persists in the air, accumulates in soils, and is found in surface and groundwater. Despite being considered safe by the EPA, the International Agency for Research on Cancer classifies glyphosate as “possibly carcinogenic to humans,” and emerging research, including this study, points to its potential role in worsening neurodegenerative diseases by contributing to pathologies, like those seen in Alzheimer’s disease. The chemical works by inhibiting a specific enzyme pathway in plants that is crucial for producing essential amino acids. However, its impact extends beyond the intended weed, grass and plant targets, negatively affecting the biological systems in mammals, as demonstrated by its persistence in brain tissue and its role in inflammatory processes. “Herbicides are used heavily and ubiquitously around the world,” says Pirrotte, associate professor in TGen’s Early Detection and Prevention Division, director of the Integrated Mass Spectrometry Shared Resource at TGen and City of Hope, and senior author of the paper. “These findings highlight that many chemicals we regularly encounter, previously considered safe, may pose potential health risks. However, further research is needed to fully assess the public health impact and identify safer alternatives.” Is glyphosate safe to use at all? The researchers hypothesized that glyphosate exposure would induce neuroinflammation in control mice and worsen neuroinflammation in Alzheimer’s model mice, causing elevated Amyloid-β and tau pathology and worsening spatial cognition after recovery. Amyloid-β and Tau are key proteins that comprise plaques and tau tangles, the classic diagnostic markers of Alzheimer’s disease. Plaques and tangles disrupt neural functioning and are directly linked to memory loss and cognitive decline. The experiments were conducted over 13 weeks, followed by a six-month recovery period. The main metabolite, aminomethylphosphonic acid, was detected in the brains of both normal and transgenic mice with Alzheimer’s pathology. Transgenic mice are genetically modified to carry genes that cause them to develop Alzheimer’s-like symptoms as they age. This allows researchers to study the progression and effects of the disease in a controlled laboratory setting. The researchers tested two levels of glyphosate exposure: a high dose, similar to levels used in earlier research, and a lower dose that is close to the limit used to establish the current acceptable dose in humans. This lower dose still led to harmful effects in the brains of mice, even after exposure ceased for months. While reports show that most Americans are exposed to glyphosate daily, these results show that even a short period could potentially cause neurological damage. Glyphosate caused a persistent increase in inflammatory markers in the brain and blood, even after the recovery period. This prolonged inflammation could drive the progression of neurodegenerative diseases, including Alzheimer’s, indicating even temporary glyphosate exposure can lead to enduring inflammatory processes that affect brain health. The data emphasizes that glyphosate exposure may be a significant health concern for human populations. The researchers stress the need for continued vigilance and intensified surveillance of glyphosate neurological and other long-term negative health effects. “Our goal is to identify environmental factors that contribute to the rising prevalence of cognitive decline and neurodegenerative diseases in our society,” Velazquez says. “By unveiling such factors, we can develop strategies to minimize exposures, ultimately improving the quality of life for the growing aging population.” The National Institutes on Aging, National Cancer Institute of the National Institutes of Health, and ASU Biodesign Institute funded this study. Source: Arizona State University Journal reference: Bartholomew, S. K., et al. (2024) Glyphosate exposure exacerbates neuroinflammation and Alzheimer’s disease-like pathology despite a 6-month recovery period in mice. Journal of Neuroinflammation. doi.org/10.1186/s12974-024-03290-6. To read the original article click here.

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