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UC Researchers Engineer New Probiotic to Target and Break Down Cancer Cell Defenses

AHA Publisher — Tue, 23 Nov 2021 08:00:36 +0000

University of Cincinnati via News-Medical – Bacteria generally have a bad reputation, as people first think of certain strains that can cause serious illnesses like pneumonia or meningitis. However, there are many helpful bacteria, known as probiotics, that assist the body in different ways. University of Cincinnati researchers have now engineered a probiotic designed to target and break down cancer cell defenses, giving therapies an easier way inside to kill tumors. The findings were recently published in the journal Advanced Healthcare Materials. Nalinikanth Kotagiri, PhD, the senior author of this study, an assistant professor in UC’s James L. Winkle College of Pharmacy and a UC Cancer Center member, studies “solid cancers” or those defined as abnormal cellular growths in “solid” organs such as the breast or prostate, as opposed to leukemia, a cancer affecting the blood. Kotagiri explains many solid cancers have an extracellular matrix made up of collagen and hyaluronic acid. The matrix forms a barrier around the cells and makes it harder for antibodies and immune cells to reach the tumors. Shindu Thomas, the first author of this study and a graduate student in the Kotagiri lab, worked with E. coli Nissle, a bacteria that has been used as a probiotic for around 100 years and is different from E. coli strains that cause sickness. Through new technology, any protein or enzyme can be manufactured on the E. coli Nissle bacteria. In this case, the bacteria was engineered to secrete an abundance of smaller structures called outer membrane vesicles on the outer edge of cells. The vesicles carry the same materials present on the bacteria itself, so researchers designed the bacteria to carry an enzyme that breaks down cancers’ extracellular matrix. Kotagiri said bacteria tend to thrive in low-oxygen and immunodeficient environments, two characteristics found in solid cancers. Because of this, the specially designed bacteria are naturally drawn to these cancers. “We took advantage of this unique feature of E.coli Nissle to home and localize into these tumors. And then once bacteria are lodged there, they start making nanoscale vesicles which carry the enzyme much deeper into the tumor matrix.” Nalinikanth Kotagiri, PhD, senior author of the study After creating the new probiotic, researchers studied the bacteria’s effect on animal models of breast and colon cancer. The bacteria is delivered intravenously about four or five days prior to the cancer treatment, allowing the bacteria time to populate and break down the cancer’s defenses and prepare it to take to the treatment. After administering the bacteria and then subsequent doses of either immunotherapy or another pharmaceutical, drugs used in targeted therapy, Kotagiri said mice survived twice as long compared to those given the cancer therapy alone. Imaging showed the bacteria and enzyme were effective at breaking down the extracellular matrix and allowing the therapy to reach the cancer cells. The study found the bacteria affected the tumors but was not attacking healthy cells in other organs like the heart, lungs, liver and brain. Kotagiri said this shows the bacteria can be safe and will not cause infection in other parts of the body, but more research needs to be done to examine its safety in large animal models and potentially humans, particularly in immunodeficient environments. “This always comes with a word of caution as to how you can utilize this strategy without causing any sepsis or any overt infections in the body,” he said. Kotagiri said his lab began to look more closely at how bacterial probiotics can address biomedical problems around 2018, as there are about one to two times as many bacterial cells than human cells in your body at any given time. “There’s bacteria in the gut, on the skin, inside your lungs, inside your mouth, even inside tumors,” Kotagiri said. “So why not take advantage of that and find interesting ways to make them a bit more proactive?” If the engineered bacteria continues to prove itself safe and effective, Kotagiri said there are a wide variety of ways to engineer the bacteria for different uses, including potentially using the bacteria to treat disease conditions in the gut, mouth and skin. There is also potential to engineer the bacteria armed with multiple proteins and molecules to make a monotherapy platform (or therapy that uses one type of treatment) rather than just facilitating combination therapy, he said. “So the bacteria can essentially serve as a mothership that would carry the necessary therapeutic payload to unique niches in the body and from there it’s a self-sustaining entity,” Kotagiri said. “While the possibilities are endless there are also significant challenges. We have to be good stewards of making that kind of evidence possible for the community to understand what are the limits and what can be done.” To read the original article click here.

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Good Bacteria May Eliminate Bad Bacteria Better Than Antibiotics

AHA Publisher — Thu, 30 Sep 2021 07:00:06 +0000

Brian Blum via Israel21c – The bacteria wars are coming. Researchers at Tel Aviv University have pitted “good” bacteria against “bad” bacteria and the good guys, it appears, are winning. If the system can be scaled, this new approach could potentially replace antibiotics, which are increasingly struggling against antibiotic-resistant “superbugs.” For the TAU study, the researchers used a toxin injection system known as a “Type 6 Secretion System.” It’s usually deployed by pathogenic (“bad”) bacteria. They introduced the system into a “friendly” bacterium, Vibrio natriegens, which is not harmful to humans. The researchers described their technology as similar to a microscopic poison arrow shot from a good bacterium to eliminate a bad bacterium under specific conditions. “The system that we built allows us to engineer ‘good’ bacteria that can recognize pathogenic bacteria, attack them with toxins, and neutralize them,” explains Dr. Dor Salomon, who co-led the study. “We know how to change and control every component in the system and create a bacterium that neutralizes different strains of bacteria. This is proof of feasibility, showing that we have the knowledge and ability to create bacteria that take advantage of this killing system and may serve as antibiotic treatments.” The current bacteria prototype is best suited for bugs that occur naturally in saltwater. This is a growing concern, as fish and seafood constitute a major food source in many regions of the world. “Their productivity is severely impaired as a result of bacteria-borne diseases,” Solomon notes, “and since we want to avoid pouring antibiotics into aquaculture farms, a biological solution such as the one we have developed is an effective alternative.” The system will eventually be adapted to treat pathogenic bacteria in humans, farm animals and plants. Tel Aviv University has filed a patent application through Ramot, the university’s technology-transfer company. In addition to Solomon, Dr. Biswanath Jana and Kinga Kappel of the department of clinical microbiology and immunology at TAU’s Sackler Faculty of Medicine participated in the research. The results were published this month in the scientific journal EMBO Reports. To read the original article click here.

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Common Drugs that Steal Your Body’s Nutrients

AHA Publisher — Mon, 08 Mar 2021 08:00:49 +0000

Dr. Josh Axe, DC, DMN, CNS – The following is an adapted excerpt from my new book “Ancient Remedies: Secrets to Healing with Herbs, Essential Oils, CBD, and the Most Powerful Natural Medicine in History“ (Little, Brown Spark) Have a fever? Take an antibiotic. High cholesterol? Use a statin. In pain? Pop an opioid. Feeling blue? Try an antidepressant. According to the Centers for Disease Control (CDC), 74 percent of doctor’s visits end with a scribbled prescription. It’s so common, many of us never think to question modern healthcare’s singular focus on medication. As a result, these lab-created drugs have stealthily taken over our lives. The Kaiser Family Foundation recently reported that 50 percent of Americans ages 30 to 49 are currently taking prescription medication, as are 75 percent of those in their 50s, and nearly 90 percent of those age 65 and older. More shocking, a third of people in their 50s — and more than half of those 65 and older — take four or more prescription drugs regularly. Our culture has come to equate healing with drugs, so much so that many of us expect our doctors to give us medication, and we often feel disregarded or mistreated when we leave an appointment empty-handed. Antibiotics are a tragic example. If you’ve ever had a chronic cough, or your child has had an ear infection, chances are your doctor prescribed one of these bacteria-killing drugs — and you might have been grateful to receive it. But here’s the thing: We now know that these medications aren’t effective at treating chronic coughs, ear infections and many other common ailments for which they’re routinely prescribed. Worse, antibiotics can be far more dangerous than we’ve been led to believe. We’ve known for a long time that they wipe out billions of healthy bacteria in the gastrointestinal tract — microbes that play a vital role in helping us digest food, fight inflammation, and maintain a healthy mood and strong immune system. But did you know that taking antibiotics repeatedly might actually increase your risk of cancer? An analysis of a large medical records database, published in the European Journal of Cancer, found that the more courses of antibiotics a patient took in the prior year, the greater their risk of esophageal, gastric, pancreatic, lung, prostate and breast cancers. Healthcare professionals in the United States write roughly 260 million prescriptions for antibiotics every year. Although the cancer risk from antibiotics is small, the drugs are jeopardizing millions of people’s health. As appalling, at least 30 percent of those millions of prescriptions are completely unnecessary, according to the CDC, because they’re prescribed for conditions that don’t respond to antibiotics. (I believe that closer to 90 percent are unnecessary, since our bodies are capable of fighting most bacterial infections on their own; and if you need extra help, a number of herbs are effective antimicrobials, with few, if any, side effects.) Those needless rounds of medication not only harm the health of people who take them, but they also contribute to the development of antibiotic-resistant strains of lethal microbes. At least two million people in the U.S. are infected with antibiotic-resistant bacteria every year, and 23,000 die because the bacteria have learned to outwit even our most powerful medications. Antibiotic resistance is one of the most urgent public health threats facing the world today. If you have a life-threatening infection, taking antibiotics makes sense. In all other instances, I agree with the sentiment of Francis Bacon, an early champion of the scientific revolution, who noted in the 16th century, “Sometimes the remedy is worse than the disease.” Antibiotics are the tip of the iceberg — and few people understand the true scope or seriousness of synthetic pills’ risks. You probably don’t know, for instance, that long-term use of most medications, both prescription and over-the-counter, can cause serious nutrient deficiencies. Proton pump inhibitors, which are routinely prescribed for acid reflux, limit the body’s ability to absorb vitamins B12 and C as well as iron, calcium, magnesium, zinc and beta-carotene. They also raise your risk of dying from heart disease, chronic kidney disease and gastrointestinal cancer. Likewise, some diuretic drugs for high blood pressure deplete your body of calcium, magnesium, thiamin, zinc, potassium, folate and iron. These nutrients are absolutely essential for the healthy functioning of your brain, heart and muscles. And those widely used types of drugs are just two examples, among dozens, of pharmaceuticals that can cause dire nutritional deficiencies. Check out this chart on commonly prescribed medications and the dangerous nutrient deficiencies they can cause. I took an oath when I became a doctor, as all physicians do. That oath was “First do no harm.” But how can any doctor be true to that oath if we rely exclusively on pharmaceuticals? As Sir William Osler, a revered Canadian physician in the 1800s, said, “The person who takes medicine must recover twice; once from the disease and once from the medicine.” What I’ve shared is just a glimpse of the vast pharmaceutical-fueled tragedy that’s quietly unfolding across the country. But there’s a deeper truth that makes our dependence on pharmaceuticals even worse: For years, Western medicine has disregarded, ignored, maligned, and sometimes intentionally buried information about safer ancient alternatives. To read the original article click here. For more articles from Dr. Axe click here.

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The 5 Best Probiotic Foods for Good Gut Health

AHA Publisher — Thu, 25 Feb 2021 08:00:38 +0000

Dr. Don Colbert – A simple way to improve your digestion is by eating more fermented foods. That’s because they contain probiotics that: Encourage the right balance of good bacteria in your digestive tract so it can filter out harmful toxins, chemicals, and waste Offset bad bacteria caused by poor diet, lack of sleep, stress, and environmental toxins to maintain a healthy gut barrier Research also shows probiotics can support a healthy immune system and may have protective effects against everything from IBS, constipation, and bloating to autoimmune disorders like Crohn’s disease and ulcerative colitis [1,2,3]. CHOOSE THESE BEST PROBIOTIC FOODS FOR A HEALTHY GUT You can reap the benefits of probiotics every day by eating the following best probiotic foods. They’re rich in that good bacteria needed for a healthy gut! FERMENTED VEGETABLES The best way to get probiotics and fiber is from whole, fermented vegetables. Sauerkraut and kimchi are the best low-carb choices. SAUERKRAUT Sauerkraut is fermented cabbage high in organic acids and enzymes. It contains probiotics, fiber, vitamins B, C, and K, iron, manganese, folate, copper, and potassium, all important for gut health and overall wellness. KIMCHI Kimchi is a reddish cabbage fermented with salt, garlic, vinegar, chili peppers, and other spices. A very popular condiment in Korea, kimchi is rich in probiotics and has lots of benefits. Besides supporting your gut with healthy bacteria, a number of studies have shown eating fermented kimchi may significantly decrease blood pressure, BMI, weight, total cholesterol, fasting, and more [4,5,6]. Note: Eat sauerkraut and kimchi in small, condiment-sized portions, as large amounts may cause bacterial imbalance. MILK OR WATER KEFIR Kefir is fermented and cultured drink made from a combination of yeast, bacteria, and either milk or water. Kefir is great for healing gut and digestion function. Although kefir initially contains sugar, its bacteria actually eat up that sugar, making it a keto-friendly food. It also contains calcium and protein (if made with milk), B vitamins, and potassium. UNSWEETENED YOGURT Yogurt can be a great probiotic keto snack. But make sure it has no added carbs from sugar or fruits, as these will take you out of the Keto Zone! Look for full-fat, organic and/or grass-fed yogurt from cows, sheep, or goats as much as possible. These options are more nutritious and less likely to contain pesticides, antibiotics, or hormones along with that beneficial bacteria. LOW-SUGAR KOMBUCHA Kombucha is a fermented black or green tea full of probiotics, enzymes, and beneficial vitamins and minerals for gut health. Kombucha has a range of health benefits for your digestion, immunity, joint health, and detoxification. Make sure the kombucha is: A low-sugar brand, as many kombucha varieties have a lot of sugar that will kick you out of the Keto Zone (check the sugar and net carb grams to be sure) Packaged in a dark glass bottle, as too much UV light can kill the good bacteria inside Organic, raw, and unpasteurized (pasteurization kills the friendly probiotics!) If you can’t find low-sugar kombucha, probiotic vinegar is a good alternative that’s still highly beneficial. DIVINE HEALTH PROBIOTIC FOODS AND SUPPLEMENTS Dr. Colbert offers several products offering the benefits of probiotics plus more: Beyond Biotics Ultra Blend Probiotics: a new product containing three clinically studied and tested strains consisting of 12 billion bacteria. Boosts immune response and natural defenses. Helps to support the natural balance of good bacteria in your gut where 70% of the immune system is found. Living Chia: ground chia seeds plus added probiotics. Fermented Green Supremefood and Red Supremefood for daily probiotics from 10 fermented veggies and four fermented grasses! Boost your gut health daily by consuming these best probiotic foods along with a healthy diet and lifestyle. More and more, science is proving that a healthy digestive system is the key to a healthy brain and body—and the power to keep your gut healthy lies directly with you! Get Dr. Colbert’s Healthy Gut Zone book today to help you understand the connection between your gut and your health. You will learn that whatever inflames your gut will eventually inflame your brain and the rest of your body. Making the right food choices will become the medicine in which you will walk and live in divine health. SOURCES 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448089/ 2. https://www.ncbi.nlm.nih.gov/pubmed/25099542 3. https://link.springer.com/article/10.1007/s11894-015-0439-z 4. https://www.ncbi.nlm.nih.gov/pubmed/21745625 5. https://www.ncbi.nlm.nih.gov/pubmed/23444963 6. https://www.ncbi.nlm.nih.gov/pubmed/24456367 To read the original article click here. For more articles from Dr. Colbert click here.

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UTSW Researchers Identify Molecule Linking Weight Gain to Gut Bacteria

AHA Publisher — Thu, 03 Oct 2019 07:00:25 +0000

UT Southwestern Medical Center via EurekAkert – “Our results also suggest that disrupting the interactions between the microbiota and the body’s clock could make us more likely to become obese…” DALLAS – Sept. 27, 2019 – UT Southwestern researchers have found a key driver of the crosstalk that helps synchronize the absorption of nutrients in the gut with the rhythms of the Earth’s day-night light cycle. Their findings could have far-ranging implications for obesity in affluent countries and malnutrition in impoverished countries. In the study, published this week by Science, Dr. Lora Hooper and her research team found that the commensal, or good, bacteria that live in the guts of mammals program the metabolic rhythms that govern the body’s absorption of dietary fat. Dr. Hooper, Chair of Immunology and a Howard Hughes Medical Institute Investigator, is senior author of the study. The study also found that microbes program these so-called circadian rhythms by activating a protein named histone deacetylase 3 (HDAC3), which is made by cells that line the gut. Those cells act as intermediaries between bacteria that aid in digestion of food and proteins that enable absorption of nutrients. The study, done in mice, revealed that HDAC3 turns on genes involved in the absorption of fat. They found that HDAC3 interacts with the biological clock machinery within the gut to refine the rhythmic ebb and flow of proteins that enhance absorption of fat. This regulation occurs in the daytime in humans, who eat during the day, and at night in mice, which eat at night. “The microbiome actually communicates with our metabolic machinery to make fat absorption more efficient. But when fat is overabundant, this communication can result in obesity. Whether the same thing is going on in other mammals, including humans, is the subject of future studies,” added lead author Dr. Zheng Kuang, a postdoctoral fellow in the Hooper laboratory. To go back in time, the story really starts with a few mice and crosstalk between two laboratories at UT Southwestern. Dr. Hooper, who runs the University’s colony of germ-free mice, which are raised in environments that have no microbes, is also a Professor of Immunology and Microbiology and a member of the Center for the Genetics of Host Defense. She holds the Jonathan W. Uhr, M.D. Distinguished Chair in Immunology, and is a Nancy Cain and Jeffrey A. Marcus Scholar in Medical Research, in Honor of Bill S. Vowell. Histone modifications – which are made by enzymes like HDAC3 – control the expression of genes that in turn make proteins that carry out the work of the cell. Not long ago, the Hooper laboratory decided to do a mouse study of histone modifications that seemed to rise and fall along with circadian rhythms. In comparing normal, bacteria-laden mice with germ-free ones, researchers discovered some histone modifications – including those made by HDAC3 – were circadian in normal mice, but held steady at a flat level in germ-free mice. That’s when Dr. Hooper contacted Dr. Eric Olson, Chair of Molecular Biology and Director of the Hamon Center for Regenerative Science and Medicine, who had done studies on HDAC3 in a different tissue, the heart. The two laboratories collaborated to develop a mouse that lacked HDAC3 only in the gut lining. The mice they generated seemed unremarkable while eating a normal chow diet. However, when the researchers fed the mice a high fat, high sugar diet similar to one commonly consumed in the United States – they found something very different. “We call it the junk food diet. I describe it as like driving through a fast food restaurant for a burger and fries and then stopping off at the donut shop,” she said. “Most mice on that diet become obese. To our surprise, those that had no HDAC3 in their intestinal lining were able to eat a high fat, high sugar diet and stay lean.” Next, they compared the HDAC3-deficient mice to the germ-free mice. The researchers found that both groups of mice showed the same flat, nonrhythmic histone modifications, confirming HDAC3’s importance in circadian rhythms. Every cell in the body has a molecular clock that governs bodily processes. The mouse study revealed that HDAC3 attaches to that cellular clock machinery to ensure absorption of fat is highest when mammals are awake and eating. “Our results suggest that the microbiome and the circadian clock have evolved to work together to regulate metabolism,” she said. Why would a system evolve to make us fat? Dr. Hooper believes it could have evolved to enable mammals to use energy efficiently in order to boost immunity in an environment with food scarcity. “This regulatory interaction probably didn’t evolve to make us obese, but when combined with today’s calorie-rich diets, obesity arises,” she said, adding that this is speculation and the team is still working to understand all the components of the pathway. “Our results also suggest that disrupting the interactions between the microbiota and the body’s clock could make us more likely to become obese. These disruptions happen frequently in modern life when we take antibiotics, work overnight shifts, or travel internationally. But we think that our findings might eventually lead to new treatments for obesity – and possibly malnutrition – by altering the bacteria in our guts.” To read the original article click here.

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‘The Most Important Way to Prevent Disease, Including Cancer’: A Dose of Good Bacteria a Day Keeps the Doctor Away

AHA Publisher — Mon, 30 Sep 2019 07:00:19 +0000

Lorie Johnson via CBN Health News – The walls of a healthy gut are semi-permeable. They are made up of tiny holes like a fine mesh strainer. These tiny holes allow vital nutrients to flow from the gut into the bloodstream and ultimately other parts of our body. Today’s leading health experts recommend putting lots of good bacteria in our gut in the form of probiotic foods like yogurt and kimchi. They also advise consuming pre-biotic fiber, like vegetables to help keep the bacteria thriving. Finally, they warn against taking antibiotics and eating processed foods, which can reduce the good bacteria in our intestines. A growing number of doctors tell their patients by following this plan, they can prevent our scariest diseases like cancer and Alzheimer’s as well as our everyday aches and pains like bloating and diarrhea. Bacteria: The Master Key to Our Cells Medical researchers spend countless hours and dollars discovering all kinds of secrets to a longer, better life. Dr. Raphael Kellman is among an increasingly large group of physicians who say the microbiome stands at the top of this list. “The most important message that has come from science in the last decade, even less, maybe seven years, the most important message from all of the scientific research is this: the microbiome is essential and key to our health,” he told CBN News. In his book The Microbiome Breakthrough, Dr. Kellman explains why he feels everyone should do what they can to increase the amount and type of living bacteria in our gut. “In my opinion, it’s the most important way to prevent disease including cancer,” he said. Dr. Heidi Nelson, a Mayo Clinic microbiome researcher, agrees. She told CBN News the tiny ecosystem in our intestines demands balance. “If you have a buildup of certain bad nutrients, let’s take for example hydrogen sulfide, we know that some bacteria produce hydrogen sulfide and others remove it and use it,” she said, “But if you have too much hydrogen sulfide that could, in some people, be the cause of the break of DNA that starts the chain reaction of colon cancer from developing.” Getting the right mix of bacteria in our gut also reduces one of the greatest causes of cardiovascular problems: inflammation. “And that can cause high blood pressure that can affect the vessels in the body and that’s all related to heart disease,” Dr. Kellman said. A healthy gut can also prevent bloating, gas and diarrhea. These problems make everyday life miserable for far too many people who don’t realize they could end their suffering by improving their gut health. Autoimmune Diseases Tied to a “Leaky Gut” Dr. Kellman says the benefits can also help autoimmune disorders like Rheumatoid Arthritis. Another autoimmune disease affecting millions is Hashimoto’s Thyroiditis, which often goes undiagnosed. Symptoms of Hashimoto’s include fatigue and weight gain. Dr. Kellman says autoimmune diseases are often caused an extremely unhealthy gut condition called “leaky gut.” The walls of a healthy gut are semi-permeable. They are made up of tiny holes like a fine mesh strainer. These tiny holes allow vital nutrients to flow from the gut into the bloodstream and ultimately other parts of our body. However, damage to the gut from certain medications, foods, stress and more cause the tiny holes to enlarge. These larger holes allow big proteins and other particles to escape the gut and into the body that shouldn’t. Because the large particles shouldn’t be outside the gut, the immune system recognizes them as foreign and attacks them, causing damaging inflammation. Sometimes the immune system even attacks healthy tissue, like the thyroid, if the tissue resembles the large particles that escaped the gut. The good news is a “leaky gut” can be repaired. In fact, Dr. Kellman teaches his patients at New York City’s Kellman Center how to do this, practicing a sub-specialty he calls Microbiome Medicine. “The microbiome is a key player in healing Chron’s Disease and Colitis, Irritable Bowel Syndrome,” he said. Proof: Microbiome Affects Our Weight Approximately one-third of all Americans are obese, a health condition that leads to many other diseases such as diabetes, cancer and more. Obesity is so dangerous it’s now the second leading preventable cause of death behind smoking. Health experts say poor gut health often leads to obesity. Dr. Vincent Pedre teaches his patients to lose weight and keep it off by achieving and maintaining the proper mix of bacteria in the gut. “When your gut is healthy it’s much easier for your body to maintain a healthy weight,” he told CBN News. In a landmark study from Washington University School of Medicine in St. Louis researchers took identical human twins with the same DNA, although one was obese and the other was thin. They put gut bacteria from each twin into germ-free mice. The animals that received the obese twin’s gut bacteria became obese, while the mice that received the thin twin’s gut bacteria remained thin, even though all the mice at the same food. In his book, Happy Gut, Dr. Pedre explains since 80-percent of the immune system is located in the gut, a healthy one can prevent everything from infections to rashes. “Which could appear like eczema on your skin, hives, allergies, asthma, even migraines are connected to poor gut health,” he said. Brain Function Linked to Gut Health Even though our brain and gut are far apart, one of the key functions of health is preventing problems with the way we think and feel, everything from depression to Alzheimer’s. Dr. David Perlmutter, author of the New York Times bestseller Brain Maker explains how an internal super-highway called the gut-brain axis carries neurotransmitters, vitamins and other essential information from the gut to the brain, mitigating or in many cases, preventing our most troublesome neurological problems such as depression, anxiety, and other mood disorders as well as Alzheimer’s disease, ADHD, Parkinson’s, even autism. “A recent study that appeared in a well-respected, peer-reviewed medical journal actually looked at giving children with autism a fecal transplant, transplanting into them healthy gut bacteria. It was a small study, only 20 participants, but the results were really quite dramatic,” he told CBN News. Thousands of years ago, Hippocrates, the Father of Medicine, famously said, “All disease begins in the gut.” Today’s health experts agree, adding the opposite is also true: all disease can be prevented in the gut. To read the original article click here. For more articles from CBN News click here.

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