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Hidden Dangers of Antibiotic Use: Did Your Doctor Tell You This?

The AHA! Team — Mon, 04 Aug 2025 05:48:38 +0000

Dena Schmidt via NaturalHealth365 – While antibiotics can help fight off unhealthy bacteria, they can also suppress the growth of the bacteria that contribute to a healthy gut microbiome and a robust immune system. Not only are bacteria developing antibiotic resistance at an alarming rate, but research from the University of Virginia School of Medicine has found that antibiotic use can also make the gut microbiome and the immune system more prone to dis-ease. The researchers believe that gut problems are due to the reduced levels of ‘good’ gut bacteria that help fight disease. While antibiotics can help fight off unhealthy bacteria, they can also suppress the growth of the bacteria that contribute to a healthy gut microbiome and a robust immune system. Additionally, a 2023 study published in Cell Reports Medicine found that prior antibiotic use can negatively impact immune responses by diminishing gut microbiome diversity and altering systemic immune function. The study demonstrated that patients with advanced gastric cancer who had taken antibiotics experienced poorer outcomes when treated with PD-1 inhibitors, a type of immunotherapy. Immune system ‘first responder cells’ impaired by antibiotic use The researchers specifically found that neutrophils, an important immune system white blood cell, were dramatically suppressed. This weakened the intestinal barrier against invading bugs and made the entire immune system less effective at fighting off infections. Neutrophils are in a sense the immune system’s “first responders” against invading foreign pathogens. Antibiotics were found to disrupt the balance of the gut microbiome to the extent that natural microbes could not properly do their job. This in turn left the gut and the entire body more susceptible to infection. Researchers are still seeking more insights into the role of the gut microbiome in health. Although the microorganisms that live inside us are still somewhat mysterious, they undoubtedly play a key role in digestion and overall health. The entire gut microbiome and immune system are compromised by the overuse of antibiotics For the study, the University of Virginia School of Medicine researchers focused on amebic colitis, a deadly parasitic infection commonly found in developing countries. Antibiotic use is widespread in many third-world or developing countries. The researchers collected and analyzed stool samples from children living in the slums of Dhaka, Bangladesh. They found those with the most severe infections had far less gut microbiome diversity. This correlated with high antibiotic use in this area, where children often receive two dozen or more antibiotic treatments by the age of two. Use vitamin C, vitamin D, and a healthy diet to bolster the immune system naturally This research adds to the mounting evidence that antibiotics should not be used unless absolutely necessary. Not only does antibiotic overuse lead to multi-drug-resistant bacteria, but it also raises the risk of infection due to impaired immune system functioning. Let this serve as a reminder to avoid antibiotics whenever possible. Instead, strive to keep your immune system strong through a healthy diet, sufficient vitamin C, and adequate vitamin D intake through sunshine exposure and/or supplementation. We at NaturalHealth365 can only hope that government health officials – especially within developing countries – will read this article and take action to help save lives. Editor’s note: For the finest quality probiotics, vitamins C and D, I suggest you look at the LuvByNature brand. Sources for this article include: NIH.govNews-Medical.net To read the original article click here.

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Are Parasites the Hidden Cause of Your Fatigue, Brain Fog, or Bloating?

The AHA! Team — Wed, 21 May 2025 05:07:23 +0000

Dr. Don Colbert – Millions of people in the U.S. unknowingly suffer from parasites, yet they are often overlooked by conventional medicine. Fatigue, brain fog, bloating, and even mood swings may not be random – they may be signs that something far more insidious is draining your energy from within. 🧬 The Magnitude of the Problem According to the CDC, over 60 million Americans are chronically infected with Toxoplasma gondii, a common parasite found in undercooked meat and contaminated water. And that’s just one type. Intestinal parasites like Giardia lamblia, pinworms, hookworms, and tapeworms are also widespread—and often undiagnosed. A 2014 study in the American Journal of Tropical Medicine and Hygiene revealed that many parasitic infections in the U.S. go undetected due to limited screening practices. ⚠️ Overlooked Symptoms of Parasitic Infection Could parasites be causing your symptoms? Chronic fatigue or low energy Gas, bloating, constipation, or diarrhea Unexplained skin rashes or acne Nighttime teeth grinding or insomnia Brain fog or poor focus Mood changes, anxiety, or irritability Weight fluctuations These symptoms are often misdiagnosed as IBS, anxiety, or food sensitivities—when parasites may be the real root cause. 🧠 The Gut-Brain-Parasite Axis Emerging research shows parasites don’t just affect digestion—they can influence brain function. A 2015 study published in Proceedings of the Royal Society B found that chronic Toxoplasma infection may alter neurotransmitters and affect behavior. Parasites can also: Increase inflammation in the gut Disrupt the microbiome Deplete essential nutrients All of which contribute to fatigue, anxiety, and mental fog. 🛡️ Top 10 Doctor-Recommended Ways to Prevent and Eliminate Parasites Naturally Rather than relying solely on pharmaceuticals, many integrative practitioners—like Dr. Don Colbert—recommend a more natural, gentle parasite cleanse that supports the body’s detox systems while addressing both exposure risks and internal imbalances. Here’s how to protect yourself and actively cleanse your system: 1. 🧼 Wash Hands Before Meals and After Handling Pets Parasite eggs can transfer from contaminated surfaces, pet fur, soil, or litter boxes to your mouth—especially if you don’t wash your hands consistently. This is one of the most overlooked yet common pathways for parasite transmission. 👉 Wash your hands thoroughly with warm water and soap for at least 20 seconds, especially: Before eating or preparing food After using the bathroom After touching pets, soil, or raw meat 2. 🔥 Cook Meat Thoroughly and Avoid Raw Pork or Wild Game Undercooked or raw meats—particularly pork, venison, and wild-caught game—can harbor harmful parasites like Trichinella, Taenia (tapeworms), and Toxoplasma gondii. ✅ Internal temperature guide: Pork: 145°F + 3-minute rest Ground meat: 160°F Wild game: 165°F Avoiding raw meat dishes or undercooked sushi made with pork or game is especially important if you’re immunocompromised or actively detoxing. 3. 💧 Filter Your Drinking Water—Especially Well Water Parasites like Giardia and Cryptosporidium are resistant to chlorine and can be found in untreated well water, mountain streams, and even some public systems. 👉 To reduce your risk: Use a high-quality water filter that removes parasites, bacteria, and protozoa Boil water when camping, traveling, or after natural disasters Consider regular testing if you use private well water 4. 🥬 Wash Produce with a Veggie Rinse or Diluted Vinegar Fruits, herbs, and leafy greens can carry parasite eggs from contaminated soil, water, or fertilizer—especially if eaten raw. ✅ Best practices: Use a veggie-safe wash or soak produce in a mix of 1 part vinegar to 3 parts water Scrub root vegetables like carrots or beets Rinse all produce thoroughly, even organic items 5. 🌍 Travel with Natural Antimicrobials (Like Garlic or Oregano Oil) Traveling to tropical or developing countries? New environments often expose you to unfamiliar pathogens in food, water, or even insect bites. 🧳 To protect your gut while traveling: Bring natural antimicrobials like oregano oil capsules, garlic supplements, or clove oil Consider a daily probiotic to support your gut lining Drink only filtered or bottled water, and avoid raw produce in high-risk areas 🌿 Natural Remedies to Cleanse the Body of Parasites Rather than relying solely on pharmaceuticals, Dr. Colbert recommends a natural, gentle cleanse that supports your entire detox system: 6. 🌿 Wormwood This bitter herb has been used for centuries to expel intestinal parasites and worms. It contains compounds like thujone, which have been studied for their anti-parasitic effects against Plasmodium and helminths. 7. 🧄 Garlic Garlic is rich in allicin, a sulfur compound that exhibits broad-spectrum antimicrobial, antifungal, and antiparasitic activity. 👉 It may help: Reduce active parasite load Inhibit reproduction of parasite eggs Support immune defense during cleansing 8. 🍃 Oregano Oil Oregano oil is one of the most potent plant antimicrobials. A 2000 study published in Phytotherapy Research showed oregano oil helped eradicate parasites in humans with gastrointestinal infections. 👉 It’s also: Antibacterial and antifungal Helpful in restoring gut balance Easy to take while traveling or cleansing 9. 🌀 Fiber for Colon Cleansing During a cleanse, fiber helps sweep out dead parasites, eggs, and toxins from the digestive tract, while also supporting healthy elimination. ✅ Dr. Colbert recommends: 👉 Fiber Zone – a delicious, psyllium-based prebiotic fiber blend that nourishes the gut and promotes regular detox support. 10. 🧬 Milk Thistle for Liver Detox As parasites die, they release toxic byproducts that your liver must process and eliminate. That’s why liver support is critical during any parasite cleanse. One of the most powerful and well-studied herbs for liver health is milk thistle. Rich in the compound silymarin, it has been shown to: Support liver cell regeneration Protect the liver from oxidative stress Enhance detoxification enzymes Help stabilize liver enzymes during toxic load [7] 🔁 For comprehensive liver support, consider combining milk thistle with other botanicals like Divine Health Nano-Glutathione Spray, NAC, alpha lipoic acid, or beet extract—found in Dr. Colbert’s Liver Gallbladder Cleanse. 💊 What Makes Dr. Colbert’s Liver Gallbladder Cleanse Unique? Divine Health’s Liver Gallbladder Cleanse is formulated with a synergistic blend of detox-supporting ingredients that go beyond milk thistle alone: Ingredient / Purpose Milk Thistle Extract (250 mg) / Regenerates and protects liver cells N-Acetyl-L-Cysteine (NAC) (1000 mg) / Boosts glutathione, the body’s master antioxidant Alpha Lipoic Acid (600 mg) / Recycles antioxidants and supports liver detox Organic Beet Root (600 mg) / Stimulates bile flow to aid gallbladder function Artichoke Extract (125 mg) / Promotes bile production and fat digestion Selenium (100 mcg) / Supports thyroid and liver enzyme activity This combination is ideal for: Supporting phase I and II liver detox pathways Enhancing glutathione levels during a cleanse Assisting with fat metabolism and gallbladder function Managing oxidative stress during pathogen die-off ✅ This formula is especially beneficial during a parasite cleanse when your detox pathways are under extra demand. 👉 You can find all of these ingredients in Dr. Colbert’s Liver Gallbladder Cleanse — a core component of a complete cleansing protocol. 🛡️ The Gentle Cleanse Protocol A typical integrative parasite cleanse may include: Herbs: Wormwood, garlic, oregano oil, black walnut, and clove Fiber: Daily intake of psyllium or plant-based fiber like Fiber Zone Liver support: Milk thistle, dandelion, leafy greens Immune boosters: Zinc, vitamin C, probiotics 🙏 Final Thoughts If you’re dealing with ongoing symptoms—despite clean labs and diets—don’t rule out parasites. Many people find that once they address this root cause, their energy, clarity, and digestion improve dramatically. “Beloved, I pray that you may prosper in all things and be in health, just as your soul prospers.” – 3 John 1:2 📚 References CDC on Toxoplasmosis Ajjampur SS et al. Am J Trop Med Hyg, 2014 Flegr J et al. Proc R Soc B, 2015 Willcox M. Trans R Soc Trop Med Hyg, 2004 Ross ZM et al. Appl Environ Microbiol, 2001 Force M et al. Phytother Res, 2000 Saller R et al. Drugs, 2001 To read the original article click here.

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Bacteria Found to Eat Forever Chemicals & Even Some of Their Toxic Byproducts

The AHA! Team — Mon, 24 Mar 2025 05:36:09 +0000

University at Buffalo via EurekAlert! – University at Buffalo study shows that strain taken from contaminated soil breaks apart the strong carbon-fluorine bonds of PFAS, as well as some of the shorter-chain PFAS left behind In the quest to take the “forever” out of “forever chemicals,” bacteria might be our ally. Most remediation of per- and polyfluoroalkyl substances (PFAS) involves adsorbing and trapping them, but certain microbes can actually break apart the strong chemical bonds that allow these chemicals to persist for so long in the environment. Now, a University at Buffalo-led team has identified a strain of bacteria that can break down and transform at least three types of PFAS, and, perhaps even more crucially, some of the toxic byproducts of the bond-breaking process. A strain of bacteria that can break down and transform at least three types of PFAS Published in this month’s issue of Science of the Total Environment, the team’s study found that Labrys portucalensis F11 (F11) metabolized over 90% of perfluorooctane sulfonic acid (PFOS) following an exposure period of 100 days. PFOS is one of the most frequently detected and persistent types of PFAS and was designated hazardous by the U.S. Environmental Protection Agency last year. The F11 bacteria also broke down a substantial portion of two additional types of PFAS after 100 days: 58% of 5:3 fluorotelomer carboxylic acid and 21% of 6:2 fluorotelomer sulfonate. The bond between carbon and fluorine atoms in PFAS is very strong “The bond between carbon and fluorine atoms in PFAS is very strong, so most microbes cannot use it as an energy source. The F11 bacterial strain developed the ability to chop away the fluorine and eat the carbon,” says the study’s corresponding author, Diana Aga, PhD, SUNY Distinguished Professor and Henry M. Woodburn Chair in the Department of Chemistry, within the UB College of Arts and Sciences, and director of the UB RENEW Institute. Unlike many prior studies on PFAS-degrading bacteria, Aga’s study accounted for shorter-chain breakdown products — or metabolites. In some cases, F11 even removed fluorine from these metabolites or broke them down to minute, undetectable levels. “Many previous studies have only reported the degradation of PFAS, but not the formation of metabolites. We not only accounted for PFAS byproducts but found some of them continued to be further degraded by the bacteria,” says the study’s first author, Mindula Wijayahena, a PhD student in Aga’s lab. The work was supported by the National Institute of Environmental Health Sciences, part of the National Institutes of Health. Other collaborators include the Catholic University of Portugal, the University of Pittsburgh and the Waters Corp. Picky eaters learn to like PFAS PFAS are a group of ubiquitous chemicals widely used since the 1950s in everything from nonstick pans to fire-fighting materials. They’re far from the meal of choice for any bacterium, but some that live in contaminated soil have mutated to break down organic contaminants like PFAS so that they can use their carbon as an energy source. “If bacteria survive in a harsh, polluted environment, it’s probably because they have adapted to use surrounding chemical pollutants as a food source so they don’t starve,” Aga says. “Through evolution, some bacteria can develop effective mechanisms to use chemical contaminants to help them grow.” The bacterial strain used in this study, F11, was isolated from the soil of a contaminated industrial site in Portugal and had previously demonstrated the ability to strip fluorine from pharmaceutical contaminants. However, it had never been tested on PFAS. Collaborators from the Catholic University of Portugal placed F11 in sealed flasks with no carbon source aside from 10,000 micrograms per liter of PFAS. Following incubation periods of between 100 to 194 days, the samples were then shipped to UB, where analysis revealed that F11 had degraded some of the PFAS. The elevated levels of fluoride ions detected in these samples indicated that F11 had detached the PFAS’ fluorine atoms so that the bacteria could metabolize the carbon atoms. F11 was not only chopping PFOS into smaller pieces, but also removing the fluorine from those smaller pieces “The carbon-fluorine bond is what makes PFAS so difficult to break down, so to break them apart is a critical step. Crucially, F11 was not only chopping PFOS into smaller pieces, but also removing the fluorine from those smaller pieces,” Wijayahena says. Some of the metabolites left behind still contained fluorine, but after being exposed to PFOS for 194 days, F11 had even removed fluorine from three PFOS metabolites. “As a caveat, there could be other metabolites in these samples so miniscule that they elude current detection methods,” Aga says. Making PFAS a desirable menu item While UB researchers say their study is a good start, they caution that the F11 took 100 days to biodegrade a significant portion of the supplied PFAS, and there were no other carbon sources available for consumption. The team now plans to research how to encourage F11 to consume PFAS faster, even when there are competing energy choices that could increase their growth rate. “We want to investigate the impact of placing alternative carbon sources alongside the PFAS. However, if that carbon source is too abundant and easy to degrade, the bacteria may not need to touch the PFAS at all,” Aga says. “We need to give the F11 colonies enough food to grow, but not enough food that they lose the incentive to convert PFAS into a usable energy source.” Eventually, F11 could be deployed in PFAS-contaminated water and soil. This might involve creating conditions to grow the strain within activated sludge at a wastewater treatment plant, or even injecting the bacteria directly into the soil or groundwater of a contaminated site, a process called bioaugmentation. “In wastewater- activated sludge systems, you could accelerate removal of undesired compounds by adding a specific strain to the existing bacterial consortium in the treatment plants,” Aga says. “Bioaugmentation is a promising method that has not yet been explored for PFAS remediation in the environment.” Journal Science of The Total Environment DOI 10.1016/j.scitotenv.2024.178348 Method of Research To read the original article about Bacteria Found to Eat Forever Chemicals click here.

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NIH Grant Supports Study of Copper’s Role in Killing Harmful Bacteria

The AHA! Team — Fri, 21 Feb 2025 06:07:49 +0000

University of Arizona Health Sciences via News-Medical – A researcher at the University of Arizona College of Medicine – Tucson received a $1.9 million grant from the National Institutes of Health to continue his research into uncovering the mysteries of copper – specifically, how it can be harnessed to kill harmful bacteria and other microorganisms. “We started using copper tens of thousands of years ago to cut down on bacterial infections. People used to store their food in copper pots, which helped cut down on spoilage. Copper doorknobs have been shown to cut down on hospital-acquired infections. We’re still finding more things it can do.” -Michael D.L. Johnson, PhD, associate professor of immunobiology Johnson said he hopes one of these potential new uses could form the backbone of a next-generation antibiotic; however, to build a solid foundation for the pharmaceutical research, his lab aims to learn more about what makes copper toxic to bacteria in the first place. The research is being made possible by an R35 grant, which is reserved for scientists with outstanding research records and the potential to make major contributions to their fields. Using Streptococcus pneumoniae as a model organism, Johnson and his team will attempt to learn what makes bacterial cells vulnerable to copper. “It’s a pretty prominent pathogen. More than a million people die per year because of these bacteria,” he said, referring to the bacteria that can cause infections in the lungs, brain, nose and blood. “Our laboratory is interested in trying to figure out how it ticks. Our way of doing that is to understand how it gets its nutrition.” The human body uses minerals such as iron and calcium, which we get from our diets, to keep bodily processes running. Bacteria are no different in that they need minerals to function, but copper, which is essential in the human diet, can be toxic to bacteria. “There are certain minerals that bacteria don’t want in excess, and that’s where copper comes into play,” said Johnson, who is a member of the BIO5 Institute. “There are a lot of ways we can weaponize copper. We’re trying to study how our body uses copper as a mechanism to kill pathogens.” Johnson believes that by flooding bacteria’s environment with excess copper, researchers may be able to trick them into building essential proteins with the wrong materials. We’re trying to study how our body uses copper as a mechanism to kill pathogens “Copper can displace iron, manganese or other metals and inactivate the protein,” he said. “It would be like me trying to start my wife’s car with my key. It doesn’t work.” Johnson will build on his previous studies investigating how S. pneumoniae reacts to copper and complement parallel studies performed in his lab to learn more about copper as an antimicrobial. He said his goal is to untangle exactly what makes copper toxic to S. pneumoniae and use that information to draw conclusions about similar bacteria. “All bacteria are different, but there are some mission-critical systems that are the same from bacteria to bacteria. How they process some of these metals is almost identical,” he said. “What I’m studying can be applied to other bacteria, but first we need to understand the basic mechanism of how these things work.” Johnson said that while new antibiotics are slow to be developed and approved, antibiotic resistance is on the rise among pathogens, meaning that infections that were once easily cured with medicine could someday be deadly again. The Centers for Disease Control and Prevention considers antibiotic resistance a danger to public health, with drug-resistant S. pneumoniae classified as a “serious threat.” “Bacteria are quite crafty. They will mutate to overcome antibiotics,” Johnson said. “Our bodies have evolved to use copper to kill bacteria, and to this day, copper is still toxic. We want to take advantage of that to help people with life-threatening infections.” This research is supported by the National Institute of General Medical Sciences, a division of the National Institutes of Health, under award no. R35GM128653. Source: University of Arizona Health Sciences To read the original article click here.

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Top 10 Places You Should DEFINITELY WASH Your HANDS After Touching

The AHA! Team — Wed, 12 Feb 2025 06:49:46 +0000

News Editors via Natural News – What is green coffee? (Article republished from GreenMedInfo.com) It’s impossible to count, but how many people have gotten sick from Covid, the flu or the common cold from simply touching something that someone else who was sick touched, and then touching your fingers to your mouth, nose or eyes? The easiest way for germs, bacteria, viruses and pathogens to enter your body and make you sick is through your wet orifices, and that’s why we are here to remind you of the top ten places where germs sit and wait to jump onto your fingers and into your body through your eyes, nose or mouth. Wash your hands with warm water and soap after touching these popular germ-laden places #1. Money So easily we forget when we handle money that it’s actually one of the dirtiest surfaces in the universe. Money can trade hands up to 100 times in a day and the odds of at least one of those people being sick are very high, especially during the cold and flu season (now). Whether it’s cash or change, the end result is the same. People sneeze and cough into their hands, they rub their eyes, pick and wipe their nose, pick their teeth and eat food with their hands, and even let their dogs lick their mouth and nostrils. Gross. Then you touch the money they touched and voila. You’re sick. #2. Touchscreens How easy it is to forget or not even realize that you’ve touched some automated screen to ring up your groceries, personal care items, household goods or even to pay the bill at the doctor, pharmacy or hospital. Germs are microscopic, that’s why they’re called microorganisms, so it only takes the tip of one finger to touch the pin pad to enter your debit or credit card secret code to pay for your goods and services. Then, you will most likely touch an itchy eye, adjust a contact lens, or shove a piece of gum or a mint in your mouth without even thinking about it. Bam – you just pushed sickness right through your gate, into your “home.” #3. Restaurant menus Wait, did you go to the bathroom and wash your hands before you left for the restaurant, or did you wait until you arrived there? Guess what? It doesn’t matter, because as soon as you touch the menu to figure out what you want to eat, you just touched one of the most hand-trafficked places on the planet. Now, most likely, you will touch your food, whether some finger-food appetizer, a sandwich, or you just drop a piece of whatever on the plate, grab it and toss it in your mouth. Researchers at the University of Arizona swabbed menus and found a whopping 185,000 bacterial organisms on them. Maybe, from now on, you should look at the menu, order, then hit the restroom and wash up. #4. Animals Americans love their pets. They are unconditional best friends. They’re good for company, entertainment, snuggling and of course, pictures and videos for sharing on social media. What happens, though, when the dog licks the owner’s face, or the cat hops up on the kitchen table after using the litter box? It’s important to wash your hands well after petting, holding or playing fetch with your pet, or anyone else’s pet. #5. Kitchen sponges Wow, these things get really nasty. People seem to keep the same ones forever and a day, until they’re chock full of grease, food particles and a million germs (over 300 species of bacteria have been found living in them) that get on your hands, your cookware, your silverware, your plates, your bowls, and then find their way into your body. Buy a bristle brush with a handle and toss out that nasty sponge. #6. Other people’s pens Bet you didn’t think of that one. You have to sign for a package, or an invoice, or sign in at a front desk, and then you touch your mouth, nose or eyes, and the person or persons who used that pen before you were sick as dogs. Pens have up to 10 times the germs of an office toilet seat. Let that sink in. #7. Doorknobs, handrails, poles and handles go anywhere and the odds are you’re going to touch at least half a dozen. At the office, store, building, bathrooms, homes and public transportation. #8. Everything at the airport, bus or train terminal this includes rails, tables, chairs, money, door handles, tray tables and any buttons you push for anything. #9. Anything at the doctor’s office, clinic or hospital. #10. People’s hands it’s too easy to shake someone’s hand or even fist bump and forget you did it. Thirty seconds later you’re touching your face and then they tell you they’ve been fighting a cold, the flu or Covid. Tune your food news frequency to FoodSupply.news and get updates on more ways to eat clean, keep germs out of your body, and avoid common illnesses. Sources for this article include: NaturalNews.com TheHealthy.com To read the original article, click here

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Antibiotics Destroy Memories?

The AHA! Team — Thu, 05 Dec 2024 06:09:34 +0000

Al Sears, MD, CNS – A study by epidemiologists at Harvard Medical School reveals a crucial link between your gut’s reaction to antibiotics – especially when taken during midlife and older – and a dramatic decline in cognitive ability as you age. Even in my earliest days of practicing medicine, I was never a big fan of prescribing antibiotics – except, of course, in cases of extreme or life-threatening infections. Because even back then, I was concerned about the damage these drugs could cause to your gut. That’s because trillions of microscopic bacteria – some that protect against certain diseases and some that can cause disease – live in your microbiome and exist in a delicate balance with each other. The problem is that antibiotics can’t distinguish between so-called “good” bacteria and the “bad” ones causing the infection. These drugs kill everything they touch. You see, this microbiome of bacteria and other microbes is essential to almost every aspect of your health – from your immune system and how much energy you have to the absorption of nutrients and even your vulnerability to depression. Now a study by epidemiologists at Harvard Medical School reveals a crucial link between your gut’s reaction to antibiotics – especially when taken during midlife and older – and a dramatic decline in cognitive ability as you age. This makes sense because your gut microflora acts like a biochemical telegraph system that sends messages along your vagus nerve directly to your brain. Don’t get me wrong. I’m not against antibiotics, per se. Since the rollout of penicillin in the 1940s, and the other antibiotics that followed, these drugs have saved hundreds of millions of lives in the fight against diseases like tuberculosis, pneumonia, and diphtheria. I am against their overuse. And now there’s one more reason to stop overusing these drugs… Studying the data of more than 14,000 women from the Nurses’ Health Study project, Harvard scientists found that taking antibiotics for two months or more during midlife was “significantly” linked to poorer cognition, learning, and memory scores , as well as reduced psychomotor speed and attention.1 The researchers noted that the decline in brain power was the equivalent of losing about three or four years of normal aging. The message of the study is loud and clear – keep your antibiotic use to a bare minimum. There are still too many doctors who hand these dangerous drugs out like candies whenever a patient appears with a sore throat, cough, or a urinary tract infection. According to the Centers for Disease Control and Prevention, around 1 in 3 antibiotic prescriptions are unnecessary.2 But the problem isn’t just confined to prescription antibiotics. Antibiotics are pumped into industrialized cattle and poultry to fight bacterial infections that spread through cramped feedlots and battery chicken farms. They are also sprayed onto fruit trees and industrial vegetable farms to prevent and treat infection. During spraying, the wind can carry them further afield into the water supply. 3 Simple Steps To Protect Yourself From Antibiotics Protecting yourself from the damage of antibiotics requires a three-pronged strategy… Avoid Cheap Meats: Cattle and poultry pumped full of antibiotics are now awash in our food supply. Make sure the meat you purchase is always grass-fed, pastured, and antibiotic free. Unless you know the source of the meat and the practices of the ranch or farm, the safest foods are USDA-certified organic foods. If your grocer doesn’t carry them, let them know you’ll shop elsewhere. Bulk up Your Immune System: A strong immune system is essential, not just for fighting infections – but also for fighting the effects of antibiotic use. Two of my favorite immune system boosters are: Anamu. Studies show this South American herb contains a powerful compound called dibenzyl trisulphide, which is a potent stimulator of your body’s “T helper cells.” Their job is to give other immune cells an extra boost.3 Anamu capsules are available at most health food stores. I suggest taking 500 to 1,000 mg per day in divided doses. Astragalus. This herb has been used in Traditional Chinese Medicine for millennia to strengthen the body’s immune defenses. Astragalus is called an “adaptogen,” meaning it helps protect the body against physical and mental stresses. I recommend 500 mg of the concentrated extract three times a day. Replace Big Pharma Meds with Natural Antibiotics: Nature has given us hundreds, if not thousands, of herbal alternatives. A few good ones are: Garlic. Research has found that garlic can be an effective treatment against many forms of bacteria, including Salmonella and E. coli. Garlic has also been shown to be effective against drug-resistant tuberculosis bacteria. Honey. Multiple studies reveal honey to be a powerhouse natural antibiotic, with the ability to inhibit more than 60 kinds of bad bacteria.4 The best is raw honey and always avoid pasteurized honey products. Curcumin. This is the main ingredient in the spice turmeric, and it’s one of the cornerstones of ancient Ayurvedic medicine. Thousands of studies prove curcumin beats a long list of modern drugs, including antibiotics. A recent study found curcumin killed 100% of the MRSA superbug within 2 hours.5 To Your Good Health, Al Sears, MD, CNS References: 1. Mehta RS, et al. “Association of midlife antibiotic use with subsequent cognitive function in women.” March 2022. Plos One. 17(3):e0264649. 2. “1 in 3 antibiotic prescriptions unnecessary: New CDC data show large percentage of antibiotics misused in outpatient settings.” CDC. May 3, 2016. Available at: https://www.cdc.gov/media/releases/2016/p0503-unnecessary-prescriptions.html 3. Williams LA, et al. “A critical review of the therapeutic potential of dibenzyl trisulphide isolated from Petiveria alliacea L (guinea hen weed, anamu).” West Indian Med J. 2007 Jan;56(1):17-21. 4. Mandal MD, Mandal S. “Honey: its medicinal property and antibacterial activity.” Asian Pac J Trop Biomed. 2011 Apr;1(2):154-60. 5. Poonam Tyagi, et al. Bactericidal Activity of Curcumin I Is Associated with Damaging of Bacterial Membrane. PLoS One. 2015;10(3):e0121313. To read the original article click here.

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Giant Viruses Found on Greenland Ice Sheet

The AHA! Team — Fri, 11 Oct 2024 08:39:57 +0000

Aarhus University via EurekAlert! – The viruses probably regulate the growth of snow algae on the ice by infecting them. Knowing how to control these viruses could help us reduce some of the ice from melting Every spring when the sun rises in the Arctic after months of darkness, life returns. The polar bears pop up from their winter lairs, the arctic tern soar back from their long journey south and the musk oxen wade north. But the animals are not the only life being reawakened by the spring sun. Algae lying dormant on the ice starts blooming in spring blackening large areas of the ice. When the ice blackens it’s ability to reflect the sun diminishes and this accelerates the melting of the ice. Increased melting exacerbates global warming. But researchers might have found a way to control the snow algae growth – and maybe in the long run reduce some of the ice from melting. Living on the ice alongside the algae, postdoc Laura Perini from the Department of Environmental Science at Aarhus University and her colleagues, have found giant viruses. She suspects that the viruses feed on the snow algae and could work as a natural control mechanism on the algae blooms. – We don’t know a lot about the viruses, but I think they could be useful as a way of alleviating ice melting caused by algal blooms. How specific they are and how efficient it would be, we do not know yet. But by exploring them further, we hope to answer some of those questions, she says. Bigger than bacteria Viruses are normally much smaller than bacteria. Regular viruses measure 20-200 nanometers in size, whereas a typical bacteria is 2-3 micrometers. In other words, a normal virus is around 1000 times smaller than a bacteria. That is not the case with giant viruses though. Giant viruses grow to the size of 2,5 micrometers. That is bigger than most bacteria. But the giant viruses are not only bigger in size. Their genome is much bigger than regular viruses. Bacteriophages – virus infecting bacteria – have between 100.000 and 200.000 letters in their genome. Giant viruses have around 2.500.000. Never found on the ice before Giant viruses were first discovered in 1981, when researchers found them in the ocean. These viruses had specialized in infecting green algae in the sea. Later, giant viruses were found in soil on land and even in humans. But it’s the first time that giant viruses have been found living on the surface ice and snow dominated by microalgae, Laura Perini explains. – We analyzed samples from dark ice, red snow and melting holes (cryoconite). In both the dark ice and red snow we found signatures of active giant viruses. And that is the first time they’ve been found on surface ice and snow containing a high abundance of pigmented microalgae. A few years ago everyone thought this part of the world to be barren and devoid of life. But today we know that several microorganisms live there – including the giant viruses. – There’s a whole ecosystem surrounding the algae. Besides bacteria, filamentous fungi and yeasts, there are protists eating the algae, different species of fungi parasitizing them and the giant viruses that we found, infecting them. – In order to understand the biological controls acting on the algal blooms, we need to study these last three groups. Haven’t seen them with the naked eye Even though the viruses are giant, they can’t be seen with the naked eye. Laura Perini hasn’t even seen them with a light microscope yet. But she hopes to do so in the future. – The way we discovered the viruses was by analyzing all the DNA in the samples we took. By sifting through this huge dataset looking for specific marker genes, we found sequences that have high similarity to known giant viruses, she explains. To make sure that the viral DNA didn’t come from long dead microorganisms, but from living and active viruses, they also extracted all the mRNA from the sample. When the sequences of the DNA that form genes are activated, they are transcribed into single stranded pieces called mRNA. These pieces work as recipes for building the proteins the virus needs. If they are present the virus is alive. – In the total mRNA sequenced from the samples, we found the same markers as in the total DNA, so we know they have been transcribed. It means that the viruses are living and active on the ice, she says. DNA and RNA in viruses At the center of the giant viruses is a cluster of DNA. That DNA contains all the genetic information or recipes needed to create proteins – the chemical compounds that are doing most of the work in the virus. But in order to use those recipes, the virus needs to transcribe them from double-stranded DNA to single stranded mRNA. Normal viruses can’t do that. Instead they have strands of RNA floating around in the cell waiting to be activated, when the virus infects an organism and hijacks its cellular production facilities. Giant viruses can do that themselves which makes them very different from normal viruses. Whereas DNA from dead viruses can be found in samples, mRNA is broken down much faster. mRNA is therefore an important marker of viral activity. In other words mRNA-recipes of certain proteins show that the viruses are alive and kicking. Not sure exactly how they work Because giant viruses are a relatively new discovery not a lot is known about them. In contrast to most other viruses they have a lot of active genes that enable them to repair, replicate, transcribe and translate DNA. But why that is and exactly what they use it for is not known. – Which hosts the giant viruses infect, we can’t link exactly. Some of them may be infecting protists while others attack the snow algae. We simply can’t be sure yet, Laura Perini says. She’s working hard on discovering more about the giant viruses and has more research coming out soon. – We keep studying the giant viruses to learn more about their interactions and what is exactly is their role in the ecosystem. Later this year we’ll release another scientific with some more info on giant viruses infecting a cultivated microalgae thriving on the surface ice of the Greenland Ice Sheet, she concludes. Journal Microbiome DOI 10.1186/s40168-024-01796-y To read the original article click here.

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CDC Study: Significantly Higher Lyme Disease Rates Among Older Adults Than Previously Reported

The AHA! Team — Mon, 23 Sep 2024 08:24:32 +0000

Dr. Sanchari Sinha Dutta, Ph.D. via News-Medical – The U.S. Centers for Disease Control and Prevention (CDC), in association with the University of Iowa, USA, has conducted an epidemiological study to determine the incidence rate of Lyme disease among older adults in the United States. The study is published in the CDC’s Emerging Infectious Diseases journal. Background Lyme disease, also known as Lyme borreliosis, is a vector-borne bacterial infection caused by a species of Borrelia bacteria that spreads to humans by the bite of infected black-legged ticks (Ixodes scapularis). The main symptoms are fever, headache, fatigue, and a specific type of skin rash called erythema migrans. While Lyme disease can present with a characteristic erythema migrans rash, it can also lead to severe complications if left untreated, including facial nerve paralysis, arthritis, and even heart rhythm irregularities. In the United States, Lyme disease most commonly occurs in the Northeast, mid-Atlantic, and upper-Midwest regions. Previous studies estimating the prevalence of the disease have used employer-sponsored insurance claims data to quantify the disease diagnoses. However, this type of data does not include information on individuals aged 65 years and above who exhibit higher susceptibility to Lyme disease than their younger peers. In this study, scientists have determined the incidence of Lyme disease among older adults in the United States using Medicare fee-for-service data that includes information on individuals aged 65 years and above. Study design The study analyzed Medicare fee-for-service data together with drug treatment data to identify Lyme disease diagnoses among individuals aged 65 years and above. The data collected during 2016 – 2019 was included in the analysis. The Medicare fee-for-service study population was compared with the 2019 US Census estimation data for individuals aged 65 years and above to ensure that the two groups were age-, sex-, race-, ethnicity- and region-matched. Lyme disease diagnoses identified in the Medicare fee-for-service data were compared with the confirmed and probable cases among individuals aged 65 years and above obtained through national surveillance. However, the study also notes certain limitations, such as slight differences between the Medicare fee-for-service population and the U.S. Census population regarding race, ethnicity, and sex. These differences, though small, were stable throughout the study period. Important observations The Medicare fee-for-service population included in the study was estimated to have a median of 17,872,466 person-years during the study period, as compared to the US Census population of 51,561,372 individuals aged 65 years and above. Person-years refer to the number of years for which persons contribute data. The proportion of individuals from neighboring high-incidence states was higher in the Medicare population than in the US Census population. Incidence of Lyme disease A total of 88,485 Lyme disease cases were identified in the Medicare population during the 2016-2019 study period. This corresponded to an average incidence of 123.5 diagnoses per 100,000 person-years. The total number of Lyme disease cases reported through public health surveillance during the same period was 34,183. This corresponded to an average incidence of 16.6 cases per 100,000 persons. Symptoms include fever, headache, fatigue, and a bullseye rash. Approximately 82% of Lyme disease cases were identified among individuals residing in high-incidence states. The median incidence of Lyme disease diagnoses was 346.9 per 100,000 person-years among residents of high-incidence states, 35.3 per 100,000 person-years among residents of states or jurisdictions neighboring high-incidence states, and 29.4 per 100,000 person-years among residents of low-incidence states. Public health surveillance data revealed that about 93% of Lyme disease cases were among residents of high-incidence states. The median incidence of these cases was 57.1 per 100,000 persons among residents of high-incidence states, 3.6 per 100,000 persons among residents of states or jurisdictions neighboring high-incidence states, and 0.6 per 100,000 persons among residents of low-incidence states. The majority of Lyme disease diagnoses occurred in the summer months. Among residents of low-incidence states, a large proportion of disease diagnoses occurred in winter months. According to Medicare and surveillance data, the majority of Lyme disease cases were identified among men. In high-incidence states, men had the highest incidence of Lyme disease for all age groups. In low-incidence states, women had a slightly higher incidence than men only in the 65–69-year age group and 75–79-year age group. Study significance The study identified more than 88,000 adults aged 65 years and above diagnosed and treated with Lyme disease during 2016 – 2019 in the United States. Most Lyme disease cases have been identified among residents of high-incidence states. The study reports a 7-fold higher incidence of Lyme disease diagnoses compared to that reported through public health surveillance. These findings are similar to the findings reported in previous claims analyses. The study also acknowledges the issue of overdiagnosis, which may partly explain the differences observed between the Medicare data and public health surveillance data. Overdiagnosis has been reported in other analyses and may contribute to the higher incidence rates observed in this older population. A variation in Lyme disease seasonality has been observed when Medicare fee-for-service data is compared with surveillance data. Some differences in gender-specific disease susceptibility have also been observed when this study is compared with previous claims analyses. Antibiotics like doxycycline are effective treatments. In previous claims analyses, male children have shown higher susceptibility to Lyme disease in both high- and low-incidence states. In contrast, male older adults have shown higher susceptibility in high-incidence states. Overall, the study findings add insight into Lyme disease patterns unique to this older population in the United States. Journal reference: Schwartz AM. 2024. Epidemiology of Lyme Disease Diagnoses among Older Adults, United States, 2016–2019. Emerging Infectious Diseases. https://wwwnc.cdc.gov/eid/article/30/9/24-0454_article To read the original article click here.

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New Antibiotic Approach Proves Promising Against Lyme Bacterium

The AHA! Team — Fri, 31 May 2024 05:32:44 +0000

Duke Health – A technique that has demonstrated success against cancer tumors could also be lethal to bacteria and other pathogens DURHAM, N.C. – Using a technique that has shown promise in targeting cancer tumors, a Duke Health team has found a way to deploy a molecular warhead that can annihilate the bacterium that causes Lyme disease. Tested in cell cultures using the Borrelia burgdoferi bacterium, the approach holds the potential to target not only bacteria, but also fungi such as yeast and viruses. The findings appear in the journal Cell Chemical Biology. Duke Health team has found a way to deploy a molecular warhead that can annihilate the bacterium that causes Lyme disease “This transport mechanism gets internalized in the bacterium and brings in a molecule that causes what we’ve described as a berserker reaction – a programmed death response,” said lead author Timothy Haystead, Ph.D., professor in Duke’s Department of Pharmacology and Cancer Biology. “It wipes out the bacteria — sterilizes the culture with a single dose of light. And then when you look at what occurs with electron microscopy, you see the collapse of the chromosome.” Haystead and colleagues used a molecular facilitator called high-temperature protein G (HtpG), which is involved in protecting cells that are undergoing heat stress. This family of proteins has been the focus of drug development programs for possible cancer therapies. Studies of this protein as an antimicrobial have also been encouraging, but the Duke team’s work appears to be the first to tether an HtpG inhibitor to a drug that enhances sensitivity to light. The researchers found that the HtpG inhibitor, armed with the photosensitive drug, was rapidly absorbed into the cells of the Lyme bacteria. When hit with light, the bacteria’s cells went into disarray and ultimately collapsed, killing them. “Our findings point to a new, alternate antibiotic development strategy, whereby one can exploit a potentially vast number of previously unexplored druggable areas within bacteria to deliver cellular toxins,” Haystead said. In addition to Haystead, study authors include Dave L. Carlson, Mark Kowalewski, Khaldon Bodoor, Adam D. Lietzan, Philip Hughes, David Gooden, David L. Loiselle, David Alcorta, Zoey Dingman, Elizabeth A. Mueller, Irnov Irnov, Shannon Modla, Tim Chaya, Jeffrey Caplan, Monica Embers, Jennifer C. Miller, Christine Jacobs-Wagner, Matthew R. Redinbo, and Neil Spector (deceased). The study received funding support from the Steven and Alexander Cohen foundation and Bay Area Lyme Foundation. To read the original article click here.

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