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Reviving the Ancient Healing Wisdom of Frankincense (Boswellia)

The AHA! Team — Mon, 30 Dec 2024 06:11:06 +0000

News Editors via Natural News – Frankincense oil may receive most of the fame and glory, but the humble Boswellia tree from which it is derived, can also create another powerful natural medicine. Oil and extracts of Boswellia have been used for thousands of years to treat numerous health conditions. (Article republished from GreenMedInfo.com) While many of us are familiar with the meditative, cleansing, and enchanting aromas of incense, the very word itself contains the powerful natural medicine from which it is derived. Frankincense, meaning “true incense” is a resin that comes from any tree species that belongs to the genus Boswellia. Spreading their branches through the Middle East, Africa, and India, this tree’s roots run deep in ancient usage and text. While all Boswellia species can produce frankincense, Boswellia serrata is the supernal species that is adorned in traditional medicinal systems like Ayurveda and Unani for producing exceptional extracts. Boswellia has a documented history of usage that dates back thousands of years Boswellia has a documented history of usage that dates back thousands of years, but it is quite possible this radical resin shared an evolutionary history with humans that greatly precludes our current estimates and archived paleoanthropological data. Just as fashion follows a circular cycle, with skinny jeans now the “newest rage”, so too is it time for a Boswellia revival and resurgence. Currently, there are 30 clinical studies on pubmed.gov, and 28 of those studies used B. serrata (the other 2 studies did not list a specific Boswellia species in their abstract). With a strong modern-day scientific backing, coupled with traditional use, Boswellia is a bright beacon pushing contemporary usage of natural medicines onward and upward. A few of its best-known therapeutic roles today include treating chronic health conditions like asthma, arthritis, cancer, and gastrointestinal issues. It has also been shown to reduce edema (swelling) from brain tumors after patients underwent radiotherapy [Kirste, 2011]. “RESULTS: Compared with baseline and if measured immediately after the end of radiotherapy and BS/placebo treatment, a reduction of cerebral edema of >75% was found in 60% of patients receiving BS and in 26% of patients receiving placebo (P = .023). These findings may be based on an additional antitumor effect. There were no severe adverse events in either group.” [Kirste, 2011] According to the American Academy of Allergy, Asthma, and Immunology in just 8 years (from 2001-2009), the prevalence of asthma jumped from 20 million people to 25 million people. That trend only seems to be increasing and if we extrapolate the data to 2017 there will be 30 million people with asthma, which is almost 10% of the population. Commonly used drugs, like inhaled corticosteroids or oral steroids may be effective, but at what cost? Serious long-term health consequences such as osteoporosis, cataracts, behavioral and mood changes, plus immunosuppression, are just to name a few [Dahl, 2006]. One of the reasons asthma is difficult to treat is because it involves an inflammatory enzyme pathway called the 5-LOX (arachidonate 5-lipoxygenase). Through a series of biochemical reactions, this enzyme produces substances called leukotrienes from the oxidation of lipid substrates, predominantly from arachidonic acid, a polyunsaturated omega-6 fatty acid [Safayhi, 2000]]. When leukotrienes are overly expressed, our immune system is excessively activated, and we enter a state of chronic inflammation, which can manifest as chronic diseases like asthma. One of the beautiful mechanisms by which Boswellia exhibits its benefits is through the prevention of degradation and oxidation to these fatty acids, thus reducing the inflammatory changes in the first place. Boswellia has also proven to be efficacious in other chronic illnesses like inflammatory bowel diseases. Collagenous colitis, which falls under the IBD umbrella, is characterized by chronic diarrhea and is typically treated with a polypharmacy approach. In a placebo-controlled, randomized, double-blind clinical study, B. serrata extract (BSE) was found to be superior in remission rates (63.6%) versus placebo (26.7%) after a six-week treatment [Madisch, 2007]. In a clinical study on chronic colitis, the remission rates were thirty percent higher in the Boswellia group (14 out of 20 patients) versus the anti-inflammatory pharmaceutical drug sulfasalazine (4 out of 10 patients) [Gupta, 2001]. In a clinical study on breast cancer patients undergoing radiotherapy, a Boswellia cream was found to significantly reduce the skin-damaging side effects [Togni, 2015]. Radiotherapy can cause extreme irritation, inflammation, itching, pain, and redness, which can severely alter a patient’s quality of life [Shaitelman, 2015]. Managing these disruptive side effects is typically done with steroids to reduce the immune response, but why risk the consequences when Boswellia is a much safer alternative? While Boswellia extract may be a formidable force, so too are the volatile oils (essential oils) derived from the gummy resin. There are four main species of Boswellia There are four main species of Boswellia from which high-quality frankincense oils are extracted: B. sacra, B. carteri, B. frereana, and B. serrata. While the chemical constituents may vary by species, in general, frankincense oil contains beneficial terpene compounds (limonene, alpha-pinene, beta-pinene, camphene, myrcene) [Woolley, 2012]. Human data may currently be limited on essential oil applications, but animal and cellular studies have elucidated some of the mechanisms responsible for these anti-cancer properties. Frankincense oil has demonstrated cytotoxic, apoptotic, and anti-proliferative properties against various cancer cell lines, including pancreatic cancer (which generally has an overall survival rate in humans of less than five years) [Ni, 2012]. Without applying reductionist principles to the innate wisdom of this plant, Boswellia probably has countless ways by which it improves health and restore balance. Whether you prefer a Boswellia extract or frankincense essential oil – caveat emptor (buyer beware) – as the purity and efficacy of products can vary greatly. Make sure to do your research and work with a company you know and trust. Read more at: GreenMedInfo.com To read the original article, click here

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Toxic Fragrance Chemicals Cause Over a Dozen Adverse Health Reactions

The AHA! Team — Wed, 29 May 2024 08:10:50 +0000

Lori Alton via NaturalHealth365 – The dangers of secondhand smoke are well known. But what about the dangers of “secondhand scents? According to a recent study published in The Science of The Total Environment, air fresheners can cause severe adverse health effects such as cardiovascular disease, systemic inflammation, and autonomic dysfunction. Another study showed that a stunning 34 percent of the American population suffers adverse effects after exposure to air fresheners and other scented products. Fully half of those affected experience health problems severe enough to be classified as “disabling.” Keep reading to discover how ordinary scented products can present serious risks to environmental quality and your health. Harm caused by fragrance products is at “epidemic” proportions In a population survey published in Air Quality, Atmosphere, and Health, researcher Professor Anne Steinemann examined the impact of common scented products on the health of 1,136 adults in the United States. Dr. Steinemann, an internationally recognized authority on environmental pollutants’ health effects, concluded that these problems’ adverse effects constituted an “epidemic.” Fragrances are found in a wide variety of commercial products, including laundry detergents, fabric softeners, cleaning supplies, air fresheners, shampoos, hair sprays, soaps, perfumes, and scented candles. Exposure also results from the practice known as “scent branding,” in which fragrances are wafted through the entire indoor environments of public spaces such as hotels, airports, and shops. In fact, Dr. Steinemann reported that 99 percent of Americans are regularly exposed to fragrance products – whether through their own use or through involuntary exposure from someone else’s use. The study revealed that almost a quarter of all Americans experience adverse effects from proximity to someone wearing fragrance products – such as perfumes, colognes, or lotions. 19 percent of the population has problems being in a room that has been cleaned with scented products, while a significant 14 percent experience health problems from the scent of laundry products being vented from homes or businesses into the environment. Reactions to fragrances can be debilitating Exposure to synthetic chemicals in fragrances can cause a range of symptoms, including migraines, dizziness, rashes, muscle cramps, mucosal symptoms, and gastrointestinal disturbances such as nausea or diarrhea. Immune system problems – such as swollen lymph glands, fatigue, and fever – can also occur, along with even more serious conditions such as anaphylaxis, loss of consciousness, seizures, and rapid or irregular heartbeat. Dr. Steinemann reported that the most common adverse effects were respiratory problems at 18.6 percent, congestion at 16.2 percent, and migraine headaches at 15.7 percent. Important note: When it comes to triggering asthma attacks, the Institute of Medicine has placed fragrances in the same category as secondhand smoke. For at least half of the individuals affected, the effects are severe enough to be potentially disabling – as defined by the Americans with Disabilities Act. In other words, the adverse effects can substantially limit major life activities such as seeing, hearing, eating, walking, learning, reading, communicating, or working. According to the survey, 15 percent of the population reported losing workdays – or even jobs – due to the effects of fragrances. In addition, 22 percent reported having to avoid specific areas because of possible exposure to a fragrance that would sicken them. And 20 percent typically decide to leave an area upon detecting a fragrance. The word “fragrance” is used to disguise a witches’ brew of toxins Outrageously, manufacturers can use a single word – “fragrance” or “perfume” – on a product label in order to designate a cocktail of up to 100 noxious chemicals and synthetic compounds. An analysis of 37 fragrance products showed that they emitted 156 different VOCs (volatile organic compounds), 42 of which are classified as toxic or hazardous under U.S. federal law. Yet, fewer than 3 percent were disclosed on the products’ labels or websites. Fragrance chemicals include human carcinogens, endocrine disruptors, neurotoxins, respiratory irritants, and toxins such as formaldehyde, acetaldehyde, chloromethane, and ethanol. Toluene, a hazardous waste product that has been shown to damage the central nervous system, is often found in fragrance samples. According to Dr. Steinemann, even low-level exposure to these toxins can cause serious (unwanted) effects like asthma attacks, anaphylaxis, seizures, and unconsciousness. In addition, synthetic fragrances have been linked to adult and childhood cancers, neurological problems, immune system weakening, and autoimmune disorders. Are we really willing to sacrifice our health for the sake of a pleasing scent? Let the buyer beware: Deceptive labels conceal toxins Warning: a label claiming the product is “green,” “natural,” or “organic” is no guarantee of safety – as even products labeled in this way can emit hazardous environmental pollutants. In another example of deceptive labeling, “unscented” products often contain perfume – a “masking fragrance” that hides the telltale scent of the synthetic chemicals. Fortunately, safe alternatives to toxic cleaning supplies and personal care items do exist. Natural health experts advise using non-toxic standbys such as baking soda, hydrogen peroxide, white vinegar, lemon juice, and unscented castile soap – while substances such as rosemary, avocado, and olive oil can be used to create natural beauty products. Dr. Steinemann, who says her study has “important implications for businesses, schools, homes, and other private and public places,” strongly recommends the institution of “fragrance-free” policies. As her study makes clear, most Americans do not want to be assaulted by unwanted fragrances – and many have shown they are willing to vacate the premises to avoid these obnoxious irritants. Maybe businesses and manufacturers will take notice. Sources for this article include: NIH.gov Sciencedirect.com Link.springer.com Link.springer.com Link.springer.com Drsteinemann.com To read the original article click here.

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Swap Out Hazardous Household Cleaning Products for These 8 Nontoxic Alternatives

AHA Publisher — Mon, 03 Oct 2022 07:00:16 +0000

Stephanie Woods via NaturalHealth365 – Every day we use products to clean our homes, sanitize surfaces, and freshen the air, all in the name of creating a healthy living environment. And why not? Ads we see on the TV, internet, and in magazines, placed by companies that claim to have not only our best interest at heart but our families as well, promise a clean, healthy, safe home. Why wouldn’t we believe them? Unfortunately, too many people are taught to trust those in power, the ones with the money, larger than life because “they know what’s best for us.” And those same people follow without question, allowing these entities to introduce toxic substances into our food, water, and the products used to supposedly clean our homes and create a healthy, safe environment. But researchers are uncovering startling information that tells a different story. The majority of common, popular household cleaning products are devastatingly harmful to humans and pets. Common Household Cleaning Products May Be More Harmful Than Previously Thought It is well documented that the only way to get past a tainted food supply is to buy local, organic, and fresh – and even that is questionable. Unsafe water is another concern that is finally coming onto the public’s radar. Toxic household cleaners are not necessarily a new conversation, but it is gaining more traction as research reveals just how hazardous they are. An alarming body of research recently published by the University of Bergen in Norway found that long-term use of cleaning products (once a week for twenty years) could have the same effect on the human body as smoking 20 cigarettes a day over a ten to twenty-year period. Researchers believe that this damage could occur due to the irritation of the mucous membranes that line the lungs caused by exposure to the chemicals in the cleaning products. Inhaling these chemicals frequently (at least once a week) over a long period of time (around twenty years) can result in airway changes that are destructive and extremely harmful. After all, the particles that are contained in the cleaning products are intended to clean surfaces, not enter the human body or be inhaled into the lungs. The containers have strong warnings about ingesting the products, but the truth is, the mucous membranes aren’t the only vulnerability; the eyes and skin are also significant conduits by which toxins can enter the body. This includes exposure to toxins during application or use and any airborne contamination lingering after the product has been used. This endangers others who may not have had direct contact with the products due to use but are present in the living environment and touch the surfaces or breathe in the fumes – even long after the product was used. The research concluded that household cleaning products create as much air pollution as cars. Exposure to Household Cleaning Products Can Lead to Severe Adverse Health Effects Chronic or long-term exposure to household disinfectants, sanitizers, and cleaners has been linked to several serious health conditions, including: Increased asthma symptoms and complications Increased risk of conditions associated with asthma such as COPD, scarred lung tissue, and lung infections Low sperm count Increased risk of developing COPD Miscarriage Damage to the nervous system Headaches or migraines Menstruation irregularities in women Symptoms of airway irritation or inflammation, including wheezing, chest pain, and shortness of breath Increased risk of pneumonia caused by exposure via inhalation Products that top the list as most hazardous include those that contain corrosive chemicals, such as drain cleaners, oven cleaners, and toilet bowl cleaners. Ammonia and chlorine are also harmful chemicals that many cleaning products proudly advertise right there on their labels. Laundry detergents, dryer sheets, and fragrance products are also laden with harmful chemicals. Many fragrances that are added to cleaning solutions can also cause serious health problems. Ditch Harmful Products and Try THESE Nontoxic Alternatives Cleaning your home should be to rid your living environment of harmful toxins, not introduce more of them. Harsh chemicals may remove dirt and germs from surfaces, but the damage they do to the human body is a steep price to pay. Even products that carry an “organic,” “green,” or “natural” label or certification can still emit air pollutants that can be harmful. Using nontoxic, truly natural cleaners will significantly reduce your risk of exposure to harmful chemicals while keeping your home healthy, clean, and sanitized. The good news is all you need are eight staples that are probably in your pantry right now: Baking soda Gentle, non-scratch scrub Oven cleaner Drain cleaner Carpet deodorizer Litter box deodorizer Castile soap Laundry soap Bath soap All-purpose cleaner for home Shower cleaner Coconut oil Antiviral, antibacterial, and antifungal cleaning solutions Clean wood furniture Sanitize wood cutting boards Use instead of WD-40 to lubricate squeaky hinges, etc. Moisturize leather goods (instead of leather conditioner) Essential oils (citrus is a good choice but eucalyptus, frankincense, peppermint, and tea tree oil are nice too) General cleaner (added to water) Insect repellant or “bug spray” (add a few drops of citrus, eucalyptus, frankincense, peppermint, or tea tree oil to water and put in a spray bottle) Room freshener Put in a diffuser during illness (frankincense cleans the air, eucalyptus helps relieve stuffy heads) Use in homemade laundry soap Hydrogen peroxide General cleaning solution Antibacterial cleaner Clean food prep areas Lemons (peel and juice) Clean and freshen refrigerator Clean and freshen garbage disposal Room freshener Clean cutting boards Clean coffee maker Furniture polish Rubbing alcohol (vodka also works) Countertop cleaners Sanitize surfaces White vinegar Disinfectant (follow with hydrogen peroxide for deeper disinfecting) Window cleaner Clean tile floors and bathtub (mix with baking soda) All-purpose cleaner for countertops (except stone, marble, or granite countertops) Bathroom grout Using truly natural, nontoxic cleaning substances will help keep a healthier, cleaner home. Sources for this article include: ChildrensHealthDefense.org Thoracic.org OEM.BMJ.com To read the original article click here.

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Environmental Toxins Linked to Rise in Chronic Health Issues Among Children

AHA Publisher — Mon, 12 Sep 2022 07:00:11 +0000

Stephanie Woods via NaturalHealth365 – Since when did it become normal for kids to have chronic illnesses? More and more children are diagnosed with chronic health issues like asthma, ADHD, type 1 diabetes, autoimmunity, allergies, obesity, and more. There was a time when a diagnosis like this would be a cause for concern, but today it barely registers as a blip on most healthcare professionals’ and even many parents’ radars. “It is what it is” seems to be the mantra. But it isn’t normal and shouldn’t be viewed as such. These health issues are not normal, especially for children. It’s time for Western medicine to take a step back, stop treating the symptoms, and get to the root of the problem. Therein lies the dilemma. Just how did we get here? Could environmental toxins be to blame? 43 Percent of Children Live With at Least One Chronic Health Condition Children are not only being diagnosed with chronic illnesses that were once exclusive to adults – some of these children are born with them. Tragically, children battling chronic health issues make up more than 70% of all pediatric intensive care admissions in hospitals across the country. An estimated 43% of children have at least one chronic health condition, according to one study that listed 20 common conditions. When they added obesity and being at high risk for developmental/behavioral issues to the mix, that number rose to 54%. These conditions included asthma, autism, diabetes, learning disabilities, and depression. Perhaps most alarming is that most of these conditions are carried on into adulthood, making them lifelong illnesses. Environmental Toxins – a Culprit for the Increase in Children’s Chronic Health Issues Environmental toxins are cited as one of the primary contributing factors in the dramatic uptick of chronic illness in children. Unfortunately, the U.S. (and most of the Western world) has a long history of harmful environmental chemicals. For example, lead has long been a culprit for a number of health issues and learning disabilities, and while it has been banned, it is still found in some places, such as lead paint that was painted over instead of being removed first. The same goes for asbestos. The pesticide DDT is another toxin that was widely accepted for a long time. While it has been outlawed, other harmful chemicals are cropping up to take its place. Each year, more and more toxic household products and harmful substances released into our environment are being identified. These toxic substances are in our homes, schools, workplaces, and even our drinking water. It can be difficult to avoid, especially if you aren’t certain exactly who your enemy is. Of course, we can’t disregard the dangers of glyphosate, indoor air pollution and the many toxins inside childhood shots. How to Reduce Environmental Toxin Exposure? It might seem like a losing battle, trying to fight a toxic environment around us. But there are steps you can take to minimize exposure. Read the labels. Read the labels on everything and avoid the more dangerous chemicals such as polychlorinated biphenyls, per-, and polyfluoroalkyl substances, and glyphosate. Filter your drinking water. Use a water filter at home that removes PCBs and PFAs from your water. Choose fresh, whole, organic foods. Organic foods have strict requirements for pesticide use so choosing these foods decreases your pesticide exposure. Avoid highly processed foods. Opt for natural, whole foods instead of overly processed foods laden with chemicals and additives. Use an air purifier. An air purifier can help filter volatile organic compounds from the air, so you are less likely to be exposed to chemicals in gas form that are released in your home from the products you use. Make your own natural household cleaning products. Vinegar, baking soda, and other natural substances can clean and sanitize your home just as well as store-bought products but without the harmful chemicals released into the air and left as residue on surfaces. The health of our children should be a top priority. They depend on us to make the world a safer place for them. We need to work harder to live up to that. Sources for this article include: ChildrensHealthDefense.org NIH.gov ScienceDirect.com EnvironHealthPrevMed.BiomedCentral.com To read the original article click here.

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How Exercise Interventions Could Help People With Asthma

AHA Publisher — Wed, 12 Jan 2022 08:00:01 +0000

University of East Anglia via Newswise – Interventions aimed at promoting physical activity in people with asthma could improve their symptoms and quality of life – according to new research from the University of East Anglia. Researchers looked at whether interventions such as aerobic and strength or resistance training, had helped participants with asthma. Although they found that these interventions worked, patients with asthma may have had difficulty undertaking them because of their difficulty travelling to fitness groups or because the interventions were not suitable for people with additional health conditions. But the team say that digital interventions – such as video appointments, smartwatches and mobile apps – could remove some of these barriers and enable patients to carry out home-based programmes in future. Prof Andrew Wilson, from UEA’s Norwich Medical School, said: “Being physically active is widely recommended for people with asthma. Doing more than 150 minutes a week of moderate to vigorous physical activity has extensive benefits including improved lung function and asthma control. “But research has shown that people living with asthma engage in less physical activity and are more sedentary than people without asthma. “We wanted to find out whether interventions – such as being asked to perform aerobic exercise a few times a week in group sessions, together with ‘goal setting’ – are effective in helping people with asthma be more active.” The team studied interventions that were designed to promote physical activity in adults with asthma. They looked at 25 separate studies from around the world involving 1,849 participants with asthma, to see whether their symptoms and quality of life were changed thanks to the interventions. Postgraduate researcher Leanne Tyson, also from UEA’s Norwich Medical School said: “We found that interventions that promote physical activity had significant benefits in terms of increasing physical activity, decreasing time spent sedentary, improving quality of life, and decreasing asthma symptoms. “This is really important because helping patients make significant behaviour changes could really improve their outcomes in the long term. “Our review also highlights the potential use of digital interventions, which were notably absent. “This is important now more than ever as patients have not been able to attend face-to-face support during the Covid-19 pandemic, and services will likely become overwhelmed. Therefore, alternative interventions and methods of delivery need to be considered.” To read the original article click here.

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Asthma May Reduce Risk of Brain Tumors — But How?

AHA Publisher — Mon, 13 Dec 2021 08:00:44 +0000

Washington University in St. Louis via Newswise – There’s not much good that can be said about asthma, a breathing disease in which the airways become narrowed and inflamed. But there’s this: People with asthma seem to be less likely to develop brain tumors than others. And now, researchers at Washington University School of Medicine in St. Louis believe they have discovered why. It comes down to the behavior of T cells, a type of immune cell. When a person — or a mouse — develops asthma, their T cells become activated. In a new mouse study, researchers discovered that asthma causes the T cells to behave in a way that induces lung inflammation but prevents the growth of brain tumors. What’s bad news for the airways may be good news for the brain. The findings, available online in Nature Communications, suggest that reprogramming T cells in brain tumor patients to act more like T cells in asthma patients could be a new approach to treating brain tumors. “Of course, we’re not going to start inducing asthma in anyone; asthma can be a lethal disease,” said senior author David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor of Neurology. “But what if we could trick the T cells into thinking they’re asthma T cells when they enter the brain, so they no longer support brain tumor formation and growth? These findings open the door to new kinds of therapies targeting T cells and their interactions with cells in the brain.” The idea that people with inflammatory diseases, such as asthma or eczema, are less prone to developing brain tumors was first proposed more than 15 years ago, based on epidemiologic observations. But there was no obvious reason why the two very different kinds of diseases would be linked, and some scientists questioned whether the association was real. Gutmann is an expert on neurofibromatosis (NF), a set of complex genetic disorders that cause tumors to grow on nerves in the brain and throughout the body. Children with NF type 1 (NF1) can develop a kind of brain tumor known as an optic pathway glioma. These tumors grow within the optic nerves, which carries messages between the eyes and the brain. Gutmann, director of the Washington University NF Center, noted an inverse association between asthma and brain tumors among his patients more than five years ago but didn’t know what to make of it. It wasn’t until more recent studies from his lab began to reveal the crucial role that immune cells play in the development of optic pathway gliomas that he began to wonder whether immune cells could account for the association between asthma and brain tumors. Jit Chatterjee, PhD, a postdoctoral researcher and the paper’s first author, took on the challenge of investigating the association. Working with co-author Michael J. Holtzman, MD, the Selma and Herman Seldin Professor of Medicine and director of the Division of Pulmonary & Critical Care Medicine, Chatterjee studied mice genetically modified to carry a mutation in their NF1 genes and form optic pathway gliomas by 3 months of age. Chatterjee exposed groups of mice to irritants that induce asthma at age 4 weeks to 6 weeks, and treated a control group with saltwater for comparison. Then, he checked for optic pathway gliomas at 3 months and 6 months of age. The mice with asthma did not form these brain tumors. Further experiments revealed that inducing asthma in tumor-prone mice changes the behavior of their T cells. After the mice developed asthma, their T cells began secreting a protein called decorin that is well-known to asthma researchers. In the airways, decorin is a problem. It acts on the tissues that line the airways and exacerbates asthma symptoms. But in the brain, Chatterjee and Gutmann discovered, decorin is beneficial. There, the protein acts on immune cells known as microglia and blocks their activation by interfering with the NFkappaB activation pathway. Activated microglia promote the growth and development of brain tumors. Treatment with either decorin or caffeic acid phenethyl ester (CAPE), a compound that inhibits the NFkappaB activation pathway, protected mice with NF1 mutations from developing optic pathway gliomas. The findings suggest that blocking microglial activation may be a potentially useful therapeutic approach for brain tumors. “The most exciting part of this is that it shows that there is a normal communication between T cells in the body and the cells in the brain that support optic pathway glioma formation and growth,” said Gutmann, who is also a professor of genetics, of neurosurgery and of pediatrics. “The next step for us is to see whether this is also true for other kinds of brain tumors. We’re also investigating the role of eczema and early-childhood infections, because they both involve T cells. As we understand this communication between T cells and the cells that promote brain tumors better, we’ll start finding more opportunities to develop clever therapeutics to intervene in the process.” To read the original article click here.

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Novel Therapeutic Strategies May Finally Bring Relief to Those Suffering from Asthma and Allergies

AHA Publisher — Fri, 29 Oct 2021 07:00:48 +0000

Rutgers University’s Office for Research via Newswise – Asthma and allergies are chronic health conditions that continue to adversely impact the quality of life for many around the world. Thanks to exciting breakthroughs by Mark Siracusa, a researcher at Rutgers, The State University of New Jersey, there may be early signs of light at the end of the tunnel. According to Siracusa, many allergies are difficult to diagnose and even harder to treat, and doctors prescribe numerous medications that merely mitigate some of the symptoms without preventing the disease. Siracusa focused his attention and research on mast cells, a type of white blood cell that is part of the first line of defense in the body’s immune system but also the primary driver for asthma and allergies. “Although we’ve known about mast cells for over 100 years, they have remained very challenging to study,” said Siracusa, director of the Research Support Core and associate professor of medicine at Rutgers New Jersey Medical School. “By taking advantage of emerging technologies, we have been able to generate tools that, for the first time, allow us to study these cells at a very granular level. These advances have allowed us to uncover new and exciting therapeutic targets that can bring significant relief to patients.” Mast cells live between the external and internal tissues, detecting foreign bodies and releasing chemicals to alert the immune system. However, allergies and asthma can occur if the mast cells overreact to non-threatening stimulants, thereby causing the immune system to kick in even when no threat exists. With funding from the Foundation Venture Capital Group (FVCG), an affiliate of the New Jersey Health Foundation (NJHF), and support from Rutgers Office for Research, Siracusa founded NemaGen Discoveries, Inc., a biotech startup aimed at advancing therapies for patients suffering from mast cell-related diseases and chronic inflammation. “The missions of NJHF and NemaGen are fully aligned – to improve the quality of life for suffering patients. We are excited that our funding will help to advance NemaGen’s research, which can potentially lead to the solution that these patients need,” said George F. Heinrich, MD, vice chair and CEO of NJHF and FVCG. “We look forward to working with Dr. Siracusa and Rutgers University to successfully commercialize NemaGen’s technology.” The Rutgers startup was established to identify novel approaches to disrupt and combat mast cells, which up until now have had the upper hand over medicine’s treatment of the two diseases. Examples of allergies include hay fever, food allergies, and eczema, as well as more dangerous diseases such as mastocytosis and mast cell activation syndrome. “Dr. Siracusa’s groundbreaking research in allergic inflammation and mast cell-mediated diseases could prove to be critical in the treatment of allergies and asthma,” said Tatiana Litvin-Vechnyak, PhD, associate vice president of Innovation Ventures in the Rutgers Office for Research. “His work epitomizes Rutgers’ ‘Jersey Roots, Global Reach’ philosophy, and his continuing research has the potential to improve the lives of millions of people all over the world.” According to the World Health Organization (WHO), hundreds of millions of people around the world suffer from allergies or asthma, including nearly 300 million with asthma alone. In the United States, the annual cost from these two diseases is over $18 billion. Siracusa described NemaGen’s next steps and what FVCG’s funding allows the company to accomplish. “The NJHF has been a long-time collaborator in advancing research at Rutgers. They immediately recognized the clinical relevance of our work at a very early stage, and provided us with business-minded guidance and seed funding to progress our drug discovery programs. With the support of both institutions, we can further advance our novel chemical compounds that possess exciting therapeutic potential.” To read the original article click here.

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Hay Fever: Natural Ways to Treat Seasonal Allergy Symptoms

AHA Publisher — Thu, 10 Jun 2021 07:00:54 +0000

Kathleen McCoy, BS via Dr. Axe – What makes spring so beautiful for many people leads to misery for those who suffer from seasonal allergy symptoms. Fresh-cut grass, blooming trees and flowers, and weeds release pollen, causing seasonal allergies (also known as hay fever) in an estimated 40 million to 60 million people each year, or up to 20 percent of people living in certain countries. Surveys have shown that when left untreated, seasonal allergy symptoms can become pretty miserable, affecting day-to-day activities and sometimes even spurring asthma attacks. For example, approximately 80 percent of people with asthma also suffer from seasonal allergies. Treating hay fever symptoms can reduce asthma-related hospitalizations and emergencies. How do you treat seasonal allergies? The good news is that natural allergy treatments can be as effective and, in many cases, even more effective than allergy medications. Some of the best options for managing seasonal allergy symptoms include making changes to your diet to reduce common allergens and inflammatory foods, taking supplements that support your immune system, and ridding your home of allergy triggers. What Are Seasonal Allergies? Allergic rhinitis is the medical term for hay fever and seasonal allergies, which affects the nasal passageways. This condition is characterized by the presence of inflammatory cells within the mucosa and submucosa. What months are allergy season? The time of the year that someone suffers from hay fever depends on the person’s specific triggers. Allergic rhinitis can occur not just in the spring, but throughout the summer and into the fall depending on the person. While hay fever frequently begins at a young age, it can strike anyone at any time. Sometimes seasonal allergy symptoms fade over the years, only to reoccur later in life. If you experience allergic rhinitis one location and move to a new area with different types of flora, your symptoms may go away or possibly get worse. Pollen is one of the main causes of seasonal asthma. Every tree, flower and weed releases pollen, but not all individuals have heightened sensitivity or allergic reactions to all types of pollens. It’s important to pay attention and recognize which things specifically trigger your hay fever symptoms. For some people, cottonwood trees and ragweed are the problems, while others struggle with grass. Research indicates nearly 75 percent of people in the United States who suffer from seasonal allergies are allergic to ragweed. Unlike grass, trees and flowers that produce pollen in the spring and summer, pollen due to ragweed is often highest during the fall. Nearly a third of ragweed allergy sufferers also experience allergic responses to certain foods. These include cucumbers, melons, zucchini, sunflower seeds, bananas and chamomile tea. (See below in the “Foods to Avoid” section.) Seasonal Allergy Symptoms What symptoms can seasonal allergies cause? The most common allergic rhinitis symptoms include: Stuffy nose/runny nose Post-nasal drip Excess mucus production Sneezing Runny nose Itchy, watery eyes Scratchy throat Tickle/irritation in the ears Decreased concentration and focus Decreased decision-making Exhaustion and sleep disorders Mood swings Irritability Low blood pressure Asthma Hives Eczema Middle ear infections Hay fever can feel similar to a common cold or sinus infection, but colds and sinus infections come and go much more quickly than seasonal allergies. Allergies usually don’t go away until the pollen is dormant. Someone suffering from seasonal allergies faces the same challenges season after season. When the allergen is pollen, mold or another airborne substance, the symptoms typically manifest in the lungs, nose and eyes. Food allergies, on the other hand, most commonly affect the mouth and stomach and may cause skin rashes. Researchers are at odds as to why this problem has worsened over the past 30 years but agree that allergies to pollen, mold and some foods are growing exponentially. We know increased pollen counts are one of the health effects of climate change; In 2000, pollen counts registered at 8,455 grains per cubic meter. By 2040, that number is projected to be well over 20,000. How do you know if you have bad allergies? The same pollen and allergens that trigger seasonal allergy symptoms can sometimes cause more serious symptoms, such as asthma attacks that result in wheezing, shortness of breath, chest tightness and difficulty breathing. This condition is referred to as allergy-induced asthma or allergic asthma. People with compromised immune systems, COPD and other respiratory conditions also need to manage their seasonal allergy symptoms to prevent further complications. Changes in diet, natural supplements, essential oils and lifestyle changes can help, but it’s also smart to work with a doctor if you suffer from multiple conditions that affect your breathing. Causes As mentioned above, examples of allergy triggers that can cause hay fever symptoms include: pollen ragweed mold dust grass residue from trees and flowers These triggers are most likely to lead to rhinitis symptoms when the weather is dry and warm. Allergy symptoms are due to our bodies releasing histamine in response to an allergen. A strong immune system is therefore key to fighting seasonal allergies, since this helps control histamine release. Did you know that your risk of suffering from seasonal allergy symptoms increases dramatically if you have certain underlying medical conditions? Asthma, unmanaged stress, deviated septum, nasal polyps, recent trauma or illness, pregnancy, and even food allergies can put you at heightened risk. According to Johns Hopkins Medicine, allergies are actually disorders of the immune system. The body over-reacts to harmless substances and produces antibodies to attack the substance. This is what causes the symptoms. You’re particularly susceptible to experiencing hay fever if you have: A weakened immune system Physical trauma or surgery Underlying illnesses High amounts of emotional and physical stress A lack of sleep You’re pregnant Stress plays a big part in keeping up immune defenses, and unmanaged stress can lead to worsened allergic reactions. Women who are pregnant — even those who’ve never suffered from allergies before — are more prone to allergic rhinitis. In fact, one in 100 pregnant women suffers from asthma during pregnancy, and many more suffer from hay fever. Safely treating allergies during pregnancy can be difficult — most over-the-counter (OTC) and prescription allergy medications aren’t considered safe for women who are pregnant or breastfeeding. Fortunately, there are numerous effective natural remedies that are safe, including for children, pregnant women and the elderly. Natural Treatments Limiting the time you spend outdoors can help relieve these symptoms of hay fever, but this isn’t the best solution. Who wants to spend their spring, summer and fall stuck indoors? Allergies can’t completely be prevented, but allergic reactions typically can be — or can at least be reduced. The treatment goal is to avoid contact with the allergen — however, this can be extremely difficult depending on your lifestyle. Treating your allergies typically requires a multi-pronged attack, one that addresses your diet, lifestyle and natural treatments. Foods to Avoid During Allergy Season: Any foods that you are allergic to, or have sensitivity to, should be avoided. If you’re not sure how far-reaching your food sensitivities are, an elimination diet can help identify foods that can make your allergies worse. Here are some common food allergens: Alcohol Caffeine Conventional dairy Chocolate Peanuts Sugar Artificial sweeteners Processed foods Melons Bananas Cucumbers Sunflower seeds Shellfish Bottled citrus juice Echinacea Chamomile Wheat Soy In addition to those above, many common food preservatives — including sodium bisulfite, potassium bisulfite, sodium sulfite and artificial sweeteners — can contribute to your allergic rhinitis symptoms. Avoid dried fruits, bottled citrus juice, shrimp and any highly processed foods. Many people also find relief when avoiding foods that cause mucus production — and it isn’t just dairy that contributes to mucus. Conventional dairy, gluten, sugar, caffeinated beverages, as well as any foods that you have sensitivities to can worsen your reaction. If you have a ragweed allergy, it’s important to avoid melons, bananas, cucumbers, sunflower seeds, echinacea and chamomile, as they can trigger allergic responses in your system. The goal of limiting foods that you have sensitivity to is to lighten the overall burden on your immune system and allow it to function more optimally. Best Foods to Enjoy During Allergy Season: The foods to avoid list may feel overwhelming, but fortunately, there are great-tasting foods that help relieve your symptoms while strengthening your immune system, including: Raw local honey Hot and spicy foods Bone broth Probiotic-rich foods Pineapple Apple cider vinegar Fresh, organic vegetables Grass-fed meats Free-range poultry Wild-caught fish Raw local honey is at the top of this list for good reason. In a randomized, controlled study published in the International Archives of Allergy and Immunology, patients who consumed honey had significantly better control of their allergies compared to those on conventional allergy medications. Local honey works to relieve symptoms because it contains local pollen that causes your allergies and helps the immune system deal with it better. A couple of tablespoons each day can relieve your itchy, watery eyes, runny nose and the general symptoms of hay fever. If you are battling excessive mucus, heat things up by eating hot, spicy foods. Hot, spicy foods help thin the mucus and allow it to be more easily expressed. Try adding garlic, onion, ginger, cinnamon and cayenne pepper to your recipes. Bone broth from chicken, beef or lamb helps ease respiratory problems and expel excess nasal mucus. It also helps reduce inflammation. Probiotic-rich foods support a healthy gut, improve digestion, increase energy levels and so much more. Probiotic foods to eat during allergy season include: Kefir Sauerkraut or kimchi Kombucha Natto Yogurt Raw cheese If you experience excessive mucus production, consume raw, organic dairy products, as the pasteurization process destroys the enzymes the body need. The enzyme bromelain found in pineapple, in addition to high levels of vitamins B, C and other essential nutrients, can help reduce your reaction to allergens. Be sure to eat the core of fresh, ripe pineapples, as it has the highest concentration of the essential nutrients you need during allergy season. Apple cider vinegar (ACV) supports a healthy gut and helps break up mucus and support lymphatic drainage. Three times per day, mix one tablespoon of ACV with one tablespoon of fresh-squeezed lemon juice and a half-tablespoon of local raw honey, and drink it. Fresh, organic vegetables — including Swiss chard, which is high in quercetin, cabbage, beets, carrots and yams — can help you fight allergic reactions. Choose vegetables that are dark green, yellow or orange for the best nutrient density during allergy season. Clean proteins, including wild-caught salmon, free-range poultry and organic grass-fed beef and lamb, are important, too. Wild salmon is rich in vitamins, omega-3 fatty acids, essential minerals and, of course, protein. If you haven’t yet made the switch to these types of clean proteins, allergy season is the perfect time. Other foods to enjoy during hay fever season including ginger, garlic, horseradish and onions. Ginger can be particularly helpful as it helps warm the body and break down toxins in your system. Best Supplements for Allergy Symptoms: It’s best to start supplements 30–60 days in advance of allergy season for the best results. Recent research shows that spirulina, butterbur and phototherapy hold promise in treating the symptoms of seasonal allergies. Spirulina — 1 teaspoon per day: Spirulina helps stop the release of histamine that causes symptoms. Consumption of spirulina was shown to significantly improve symptoms, including nasal discharge, sneezing, nasal congestion and itching, in a double-blind, placebo-controlled study. Quercetin — 1,000 milligrams per day: Research shows that quercetin, the flavonoid that gives fruits and vegetables their rich color, stops the production and release of histamine. Please note that quercetin may interfere with certain medications, including antibiotics, cyclosporine and other medications changed by the liver. Butterbur — 500 milligrams per day: Butterbur has traditionally been used to treat bronchitis, excess mucus and asthma. In a recent study of hay fever sufferers, it also was found to be as effective as some allergic rhinitis medications. However, young children and pregnant or breast-feeding women should not take butterbur supplements. Probiotics — 50 billion international units (2–6 capsules) per day: Probiotics modify the intestinal flora in the gut and help...

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Common Asthma Drug May Help People Fight COVID: ‘It Should Reduce Hospitalizations by Around Half’

AHA Publisher — Wed, 09 Sep 2020 07:00:53 +0000

Lorie Johnson via CBN News – Scientists are looking into whether a drug commonly used by people with asthma and other breathing conditions can also be used to successfully treat COVID-19. The drug could prevent patients in the early stages of the disease from landing in the hospital. Ever since COVID-19 burst on the scene in early 2020, scientists saw right away it goes for the lungs. Then came a surprise when they saw that people being treated for certain lung diseases seemed oddly protected against the coronavirus. These COVID-19 patients were people with asthma and the lung disease COPD and were living in Asia, Europe, North America, and elsewhere. Scientists noticed they were either underrepresented or completely absent from data surrounding pandemic cases, according to researcher Dan Nicolau of The Queensland University of Technology. “Which suggests that something these patients are doing is keeping them out of hospital,” he told CBN News. “It’s not keeping them from getting COVID but it’s keeping them, at least in some of the cases, keeping them from getting very sick.” Apparently, these patients who contracted COVID-19 were already using an inhaled corticosteroid, such as Budesonide, to treat their asthma or COPD. Nicolau leads a clinical study being conducted by QUT and Oxford University testing Budesonide’s effectiveness when given very soon after a person becomes infected with the novel coronavirus. “It should reduce hospitalizations in our math model, by around half,” said professor Nicolau. Unwilling to wait for study results, some doctors have begun prescribing inhaled Budesonide to patients who were recently diagnosed with COVID-19, such as Dr. Ted Trimble, who practices family medicine at Titus Regional Medical Center near Dallas, Texas. “I can’t do medicine without my faith. I often say to my patients upfront, ‘I consult Dr. Jesus’,” he told CBN News. Dr. Trimble said he’s prescribed Budesonide to ten COVID-19 patients with plans to continue. “Nine out of ten did extremely well within the first few treatments,” he explained. “They could breathe much easier, one needed to go to the hospital for oxygen support but did not require intubation or ventilation.” Likewise, Dr. Tom Rogers, an integrative medicine specialist who practices in the Knoxville, Tennessee area has also seen positive results in 11 patients and counting. “I started using it with no side effects and it seems to be if you treat early along with a Z-pack and zinc it really is very effective,” he told CBN News. Dr. Rogers gives the Budesonide specifically to COVID-19 patients with respiratory symptoms like a mild cough, wheezing, or shortness of breath. In cases where patients exhibit different common symptoms such as loss of smell, achiness, or fatigue, Rogers usually prescribes the controversial drug Hydroxychloroquine with the antibiotic Azithromycin, also known as a “Z-pack”, and zinc. “I am a Christian and my faith really carries me through every day caring for people all these years,” he said, adding, “There’s another very powerful thing that works against any disease or illness. It’s called prayer.” While the US Food and Drug Administration does not recommend Budesonide or Hydroxychloroquine to treat COVID-19, there has been movement. FDA Commissioner Stephen Hahn, M.D. now admits some Hydroxychloroquine studies “suggest a benefit” and pointed out doctors are free to prescribe drugs “off label” and that the FDA “does not regulate the practice of medicine.” To read the original article click here. For more articles from CBN News click here.

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