amino acid Archives - Amazing Health Advances

Amino Acids & Mental Health

The AHA! Team — Fri, 20 Sep 2024 08:24:17 +0000

Dr. Caroline Leaf – In this podcast (episode #589) and blog, I talk to Angelo Keely, co-founder and CEO of Kion Aminos, about the role protein plays in our mental and physical health, why amino acids are important, and how to strengthen your mind, brain, and body and increase your longevity! After a near-death experience in his late teens, Angelo decided that taking charge of his own health should play an integral role in his life. He eventually started a new business based on his own experiences and his passion to help people improve their wellbeing and live their best lives, called Kion Aminos. I am a big fan of Kion Aminos, which I take every day as part of my mental and physical regimen. As you have heard me talk about on my podcast and in my books, our mental health and physical health are intertwined. Both are heavily influenced not only by what we put in our bodies, but by what our bodies are missing, or deficient in, as well. This is one of the reasons I want to make sure I am getting enough protein. For our cells to be able to communicate with each other, we need to consume adequate protein for the essential amino acids it contains. Our body breaks down protein into its individual essential amino acid components, which then circulate through our blood and are used by the brain and body for everything from building muscle to forming neurotransmitters and hormones. Our body breaks down protein into its individual essential amino acid components These essential amino acids are very different from other macronutrients like carbohydrates or fats, which are energy sources. Protein can be converted into an energy source, but this is not its primary use. When we consume protein, our body wants to break down protein into individual amino acids and use them to fuel all the amino acid and protein requirements in the mind and brain. Many of us get our daily intake of protein from whole food protein sources like eggs, poultry and tofu, but most people don’t know we can also get what we need most from protein – essential amino acids – directly as a supplement, hence the reason Kion Aminos is an important part of my life, and why Angelo is so passionate about what he does: in so many ways, amino acids are essential to life! They play an important role not just in muscle building and physical recovery but also in the mind-brain connection. When we go through life, our experiences are wired into the brain on several different levels, which involves the production of amino acids. Amino acids help build many things in the brain and body, including our experiences! Without amino acids, we would not be able to experience life as we know it. In fact, over 50% of our solid body mass is made up of proteins (and thus amino acids), including the heart, kidneys, muscles, neurotransmitters, neurons and so on. Our experience of existing mentally could even be called an amino acid experience! It is important to note that proteins are in a constant state of breaking down and then re-synthesizing to function optimally. When these proteins break down into amino acids, some cannot be reused, which eventually leave our body in our urine. These amino acids have to be replenished through what we eat and drink so that our brain and body can continue functioning optimally. Proteins are in a constant state of breaking down This means that when we consume protein (and thus amino acids), we are not just giving our brain and body energy to burn; we are also giving ourselves the building blocks that make up the brain, heart, kidneys, muscles and so on. We are actually protecting the most vital parts of ourselves by building up and strengthening our muscles–it is not just about moving fast or looking good. Many people think that the primary function of skeletal muscles is to help the body move, but our muscles are also the primary reservoir of amino acids for the rest of the brain and body. If we stop consuming amino acids or proteins, then the body will start breaking down our muscle tissue to get amino acids into the blood and to vital parts of the body like the liver, heart or brain, so that these organs can function. Amino acids really are the building blocks of life! And supplementing so we make sure we get the amino acids we need is incredibly important as we age. Research shows that, after the age of 30, our ability to break down proteins and get the essential amino acids we need decreases, so we need to make sure we have good sources of these amino acids in our diet to maintain our health and improve our longevity. Of course, with so many supplements out there, we shouldn’t just take the first amino acids we see, as not all products are created equal. This is why Angelo and the team at Kion are passionate about making premium, clean, research-backed amino acid supplements and foods that support a long, fun, active life. They meticulously select the highest quality natural ingredients and blend them into complementing supplements and functional foods that maximize wellness, performance, and longevity. Their products contain all 9 essential amino acids our bodies cannot make by themselves, already broken down from protein and ready to be absorbed and used by your body, making it 2X to 8X more effective than protein. I also love that the Kion formula is completely transparent and backed by over 20 years of research. This is something I am particularly passionate about as a woman in her 60s. As we get older, we need certain amino acids to help us maintain our wellbeing and longevity. And low-dose (3g), leucine-rich, essential amino acids (like those found in Kion Aminos) can help stimulate muscle synthesis equivalent to 20g of whey protein in older women at rest and after exercise. This means that, for women like myself, Kion Aminos can be 6x more effective than an equal amount of whole food protein at stimulating muscle synthesis to help maintain my physical and mental health, quality of life and longevity! If you want to try Kion Aminos for yourself, for a limited time you can get 20% of your order at getkion.com/drleaf! For more on why amino acids are so important for our mental and physical wellbeing, listen to my podcast with Angelo (episode #589) and check out Kion Aminos’ amazing products. Podcast Highlights 2:05 Proteins, amino acids & why they are so important 9:43 What essential amino acids are & why we need them 11:40 Great sources of essential amino acids 12:30 Why essential amino acids are important as we age 20:45 Why we all need to strengthen muscles—this is not for bulking up! 25:40 Why we want to be proactive when it comes to our health 27:06, 32:51 Why we need to be careful what supplements we take & why I love Kion Aminos 33:55 Why Angelo started Kion Aminos & his advice to fellow entrepreneurs and people who want to start their own business This podcast and blog are for educational purposes only and are not intended as medical advice. We always encourage each person to make the decision that seems best for their situation with the guidance of a medical professional. To read the original article click here.

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Support Coronary Health With THIS Amino Acid

AHA Publisher — Mon, 21 Nov 2022 08:00:48 +0000

Lori Alton via NaturalHealth365 – Every 34 seconds in the United States, somebody dies of heart disease. In fact, cardiovascular disease is currently the leading cause of death in the nation, claiming about 697,000 lives in 2020 alone. In coronary heart disease – the most common type of heart condition – arteries can’t deliver enough oxygen-rich blood to the heart. Lysine, a common amino acid, is believed to inhibit plaque build-up and promote heart health. Moreover, a this study suggests that lysine can lower high blood pressure – a known risk factor for heart disease. Let’s see what other health benefits this nutrient has to offer. Lysine Is a “Jack of All Trades” That Supports the Health of Multiple Systems First of all, what is lysine’s role in the body? A building block for proteins, it is vital for muscle growth and maintenance. And, as it helps to prevent the loss of lean muscle mass, it may be particularly beneficial in improving strength and mobility in elderly people. Lysine also helps to produce collagen – a protein needed for speedy wound healing, healthy skin, and flexible arteries. In addition, lysine contributes to bone health and wards off osteoporosis by supporting the absorption of calcium. It also supports the immune system by assisting the production of infection-fighting antibodies. As if that weren’t enough, this versatile nutrient is also involved in the creation of enzymes and hormones. One more surprising attribute of lysine is its ability to ease anxiety and lower levels of the “stress” hormone, cortisol. In one randomized, placebo-controlled study, a week of supplementation with lysine and arginine reduced anxiety and lowered cortisol in healthy adults with stress-induced anxiety. Finally, this amino acid is believed to help control outbreaks of “cold sores” resulting from the herpes simplex Type 1 virus. Clearly, when it comes to sustaining health, lysine “wears many hats.” Supplementation May Help Keep Blood Pressure in Healthy Range Some researchers maintain that lysine can reduce hypertension (high blood pressure) by preventing pressure buildup in the arteries. Recent research has shown that people with suboptimal lysine intake and high blood pressure experienced lowered blood pressure when supplemented with lysine. In a randomized, placebo-controlled study published in BMC Nutrition, 1,000 mg of lysine a day for 112 days significantly lowered systolic blood pressure (the top number, which measures the force of each heartbeat). In fact, this measurement dropped by an average of almost 20 points! The scientists concluded that the amino acid may be a “useful nutrient” when added to hypertension medications. Lysine May Promote Heart Health by Reinforcing Collagen Nobel prize-winning researcher Linus Pauling maintained that lysine may help promote heart health by strengthening collagen (“like steel rods in concrete,” in his colorful analogy), thereby helping to prevent collagen fracture and blood clots. When there are extra amounts of lysine and the amino acid proline in the blood, Pauling declared, the lipoprotein-a attachment sites are obstructed by lysine, creating a “Teflon-like” coating around the particles and preventing them from binding to the arterial walls. In this way, lysine is believed to prevent plaque buildup – reducing the threat of atherosclerosis and high blood pressure. Unfortunately, these findings have been generally greeted with indifference by many conventional cardiologists. Mostly due to the ground-breaking work of Linus Pauling (and others, such as Dr. Sidney Bush), some natural health experts advise a combination of vitamin C and lysine to reverse atherosclerosis and help prevent heart attacks. For example, the Dr. Rath Health Foundation’s Cellular Recommendations for Heart Health call for 100 to 500 mg of the nutrient a day, along with other amino acids, bioflavonoids, vitamins, and minerals. Boost Dietary Intake With Meat, Beans, and Nuts Lysine is an essential amino acid, meaning it is not produced by the body and must be obtained through diet or supplementation. It is found in animal products, including grass-fed beef, dairy products, cage-free eggs, and wild-caught salmon or sardines. For vegetarians and vegans, no worries: lysine is also found in wheat germ, beans, lentils, amaranth, buckwheat, and nuts. While most people get enough lysine through diet, supplementation may be advisable. People recovering from burns or other severe injuries – and those who perform frequent, high-intensity workouts – may require a higher-than-average intake. Natural healers typically recommend amounts of up to 3 grams a day – but consult your own integrative doctor before supplementing. Capable of promoting stable mood, bone health, heart health, and better immunity, lysine is clearly too important to take for granted. Eating a healthy diet can help ensure that you are consuming enough of this health-promoting amino acid. Sources for this article include: MedicalNewsToday.com DrRathFoundation.org NIH.gov CDC.gov Healthline.com To read the original article click here.

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Gene-Edited Tomato Promoted as Therapeutic, But Is It Even Safe?

AHA Publisher — Fri, 11 Mar 2022 08:00:56 +0000

Stephanie Woods via NaturalHealth365 – Engineered foods are becoming more and more prevalent as scientists seek to make our whole, natural fruits, vegetables, grains, and meats into substances that vaguely resemble the original product. They claim to be doing it all in the name of better health, but is it really? Japanese startup, Sanatech, is behind the launch of the CRISPR gene-edited tomato, the first of its kind in the world. The engineered fruit contains higher levels of the sedative Gamma-AminoButyric Acid or GABA. It is garnering a mixed reception, with some experts touting its supposed health benefits and others voicing concerns about its safety for human consumption. The Trouble With GABA and Gene-Editing GABA is an amino acid that is believed to help lower blood pressure and increase relaxation. It is naturally found in tomatoes in small amounts, but the gene-edited tomato contains five times more GABA than a regular one. This has some scientists very concerned. In Japan, GABA is considered to be a health-promoting substance. However, studies show mixed findings. More disturbing, though, there have been absolutely zero studies showing that consuming the CRISPR tomato has any health benefits for humans or is safe to consume. There haven’t been enough studies done to determine if GABA is safe to use. It seems to be safe in the amounts commonly found in foods, but higher amounts could cause problems. There just isn’t enough evidence for many experts to feel comfortable with these higher amounts – and worse, putting in our food. Gene-editing has also raised some serious concerns. Research has shown that it can lead to serious chromosomal damage. Eyebrow-Raising “Marketing” – or Lack Thereof Sanatech is stepping lightly around the so-called benefits of the gene-edited tomato. In fact, they are very careful to avoid any claims of its ability to promote relaxation or lower blood pressure. To get around this, the company is using a more general tactic, marketing GABA as a substance that can help with relaxation and lower blood pressure. It then follows up by explaining that its tomatoes are fortified with high levels of GABA. Essentially, they are saying it without saying it, and this is causing some concern within the research community, especially since there is little evidence that even supports the substance as a viable health supplement, much less a safe one. Another Genetically Modified Tomato Is Also Causing Concern Cathie Martin of the UK’s John Innes Centre has developed a purple tomato using an older genetic modification technique. She plans to market to the public directly even though there have not been any human intervention studies on the tomatoes. This means that the health effects of conventional tomatoes and genetically modified tomatoes have not been studied or compared. The fact that she does not intend to make any claims regarding health benefits is of little comfort. However, the media and the John Innes Center have created a great deal of hype regarding the tomatoes’ cancer-fighting properties over the past few years. Warning from health organizations that state there is no evidence supporting the claims has not deterred or stopped them. With weak government regulations on genetically modified crops, these foods are already making their way onto American soil. After that, these scientifically-altered foods will be coming to a market near you … and most consumers will have no idea it’s happening. Sources for this article include: ChildrensHealthDefense.org FruitNet.com ChildrensHealthDefense.org To read the original article click here.

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What Is the Difference Between Slow and Fast Proteins?

AHA Publisher — Fri, 10 Dec 2021 08:00:06 +0000

Rakefet Arieli via The Jerusalem Post – There’s a difference between “slow” proteins, which are recommended to be consumed in food or drink before bed and “fast” proteins, which will do the work for you after you exercise. How can you choose the right one and which products do you need to know about before the next workout? Here are the answers. Adequate protein intake is crucial for our health. It contributes to muscle mass and bone health, and also helps us maintain a healthy weight. Since awareness of proper protein intake has increased in the last few years, companies started marketing new protein-rich products, such as yogurts, milk drinks, protein bars and protein powders. But What Exactly Should You Consume and How Do You Choose? Let’s organize all the information you need. Proteins are made up of chains of amino acids. There are 20 of these, and our body needs them all. The difference between the proteins is in the number of amino acids in the chain, their type, the order of their connection and the spatial structure in which they’re organized. Of the 20 amino acids, the amino acid leucine was found to be most effective for consumption after physical exertion, as it contributes to the repair and renewal of muscle tissue damaged during physical exercise, even slight tears which occur on a regular basis. Proteins are found naturally in milk and dairy products, meat and meat products, eggs, soy and legumes. Proteins differ according to the rate of their absorption in the body. With “slow” proteins the rate of increase of amino acids in the blood is slow, and with “fast” proteins the rate of increase of amino acids in the blood is fast. “Slow” proteins, such as casein protein, should be consumed when the time window for building muscle is long, for example before bed. “Fast” proteins, such as whey and soy, are recommended for consumption when the time window for building muscle is short, such as at the end of a workout or between workouts. There are many points to consider when choosing the protein product we want to eat or drink in different situations: is it part of a meal, something to meal after a workout, or a late night bitetaste, type, quantity, quality, availability, etc. If you want to consume protein after physical exertion, nutritionists recommend 20-40 grams of whey protein, which contains one-three grams of leucine. Cow’s milk naturally contains about 80% casein protein and 20% whey. When dairy products are produced changes in the protein content can be made which affects the amount and type of protein in the products. A protein that has undergone an isolation process will contain the highest amount of whey protein and the highest amount of the amino acid leucine. So, it will be the most recommended protein to consume after a workout. Today, you can find a variety of protein drinks that differ from each other in the process of protein production in nutritional values, which vitamins and minerals are added and in how they taste. Rakefet Arieli is a clinical and sports dietitian at Shaare Zedek Hospital Sports Medicine Center. This article was written in cooperation with Yotvata and was published on our sister publication, Maariv. To read the original article click here.

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Eliminate Toxic Debris From Your Body with THIS Incredibly Effective Therapy

AHA Publisher — Thu, 20 May 2021 07:00:26 +0000

Sima Ash via NaturalHealth365 – Far-infrared (FIR) radiation is a subdivision of the electromagnetic spectrum that has been investigated for biological effects with very encouraging results. I have clients who have added this modality as part of their overall treatment plan for everything ranging from autism to heart conditions. How does FIR work? The body experiences FIR wavelength energy as a gentle radiant heat that can penetrate up to 1.5 inches beneath the skin. An article published in Photonics & Lasers in Medicine states that FIR energy is sufficient to exert rotational and vibrational modes of motion in bonds forming the molecules (including water molecules) and resonate with our cells. FIR Saunas Improve MULTIPLE Cardiovascular Conditions FIR saunas are frequently used in Japan and Korea, where it is referred to as Waon therapy. Studies have shown that FIR saunas are particularly beneficial for chronic heart failure and peripheral arterial disease and have been shown to improve cardiac and vascular function and reduce oxidative stress in patients with chronic heart failure. In addition, German medical researchers concluded that just 1 one-hour session of FIR could significantly reduce blood pressure due to persistent peripheral vessel dilation. They also noted that blood viscosity was improved. That’s Not All! People With Arthritis and Type 2 Diabetes Can Also Benefit A study of patients with rheumatoid arthritis showed a reduction in pain, stiffness, and fatigue during infrared sauna therapy. In addition, far-infrared sauna was associated with improved quality of life in people with type 2 diabetes mellitus. The author concluded that the uptake in the use of infrared saunas is greater than the uptake of other lifestyle interventions. FIR Saunas Can Even Help Children With Autism, According to Study Many parents report that their children with autism seem to improve when they have a fever. An article published in Medical Hypothesis states that the release of the amino acid glutamine could be the reason for the improvement in autism symptoms. In people with autism, glutamine in the blood and brain is low, but during a fever, glutamine is released from skeletal muscles as provisional fuel, and the glutamine is metabolized by the intestines – just as if the amino acid had been ingested. The International Journal of Hypothermia derived the same conclusion. They found that a fever or hyperthermia may alter glutamate levels in the brain and therefore be able to impact the symptoms of autism. Working with this information, many physicians have incorporated FIR into their practice to help children with autism. Here Is How FIR Therapy Helps Reduce Toxic Burden and Achieve Optimum Health Our skin is a major elimination organ, but many of us do not sweat regularly. This could be due to insufficient physical activity, sun exposure, or wearing synthetic or tight-fitting clothing. Simply put, sweating is natural (and essential) for optimal health. Using FIR saunas helps restore skin elimination by helping the body eliminate toxic debris. In fact, FIR therapy was used as part of the protocol to help September 11th firefighters recover – after being exposed to toxic chemicals as part of the World Trade Center rescue and clean-up efforts. Exposure to solvents and other chemicals has been linked to psychiatric disorders, including depression, mood disorders, anxiety, and detoxification has helped many people recover. In my practice, we use CEASE therapy, a detoxification protocol that has been assisting children with autism and other disorders for many years. Far-infrared sauna therapy could be a wonderful adjunct for many who have trouble with detoxification and need help assisting their bodies to remove toxic debris. As a precaution, please check with your healthcare practitioner before starting FIR – as there are protocols that need to be followed, including specific vitamins and minerals before and after sauna sessions and, of course, assuring that enough water is consumed during the session. It is also important not to bring in reading materials or plastic containers, for your water, into the sauna as those can contain the exact chemicals you are attempting to detox. About the author: Sima Ash of Healing 4 Soul is a clinical and classical homeopath and certified clinical nutritionist who utilizes a unique approach pioneered by Tinus Smits, M.D. called CEASE therapy. CEASE treatment aims to systematically detoxify the causes of illness, leading to step-by-step improvement and restoration of health in the individual. For additional information, please visit – Healing4Soul.com. Sources for this article include: NIH.gov NIH.gov TownsendLetter.com NIH.gov To read the original article click here. For more articles from NaturalHealth365 click here.

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What Is Betaine? Benefits, Signs of Deficiency and Food Sources

AHA Publisher — Wed, 16 Sep 2020 07:00:51 +0000

Jillian Levy, CHHC via Dr. Axe – Betaine (BET) is an amino acid that has been shown to have potential benefits for fighting heart disease, improving body composition, and helping promote muscle gain and fat loss. This is thought mostly to be due to its ability to promote protein synthesis in the body. Never heard of betaine before? Also known as trimethylglycine, it is becoming more popular in supplements recently but is actually not a newly discovered nutrient. While it’s been studied for its positive impacts on preventing heart disease for quite some time, only recently has betaine been included more often in exercise-focused and energy supplements, protein powders and other products geared at improving exercise performance and body composition. What Is Betaine? Betaine is a trimethylglycine and derivative of the nutrient choline. In other words, choline is a “precursor” to betaine and must be present for betaine to be synthesized in the body. It’s created by choline in combination with the amino acid glycine. Just like some B vitamins, including folate and vitamin B12, betaine is considered to be a “methyl donor.” This means it aids in liver function, detoxification and cellular functioning within the body. Its most crucial role is to help the body process fats. What is betaine used for in supplement form? Probably the most extensively researched benefit of betaine is supporting conversion of the amino acid homocysteine in the blood to methionine. Although amino acids are critical compounds needed for many body functions, studies show that high levels of homocysteine can be harmful to blood vessels, potentially leading to the development of plaque buildup and the condition called atherosclerosis (clogged arteries). Health Benefits 1. Supports Heart Health Betaine is best known for helping reduce plasma homocysteine levels, which is directly related to lowering the risk for heart disease. A high homocysteine concentration is a potential risk factor for cardiovascular disease, but studies suggest that this condition can be reduced through regular betaine supplementation. High plasma levels of homocysteine greater than 15 μmol/L are present in an estimated 5 percent of the adult population and in as many as 50 percent of those with cardiovascular disease and stroke. According to a 2013 study, “supplementation with at least 4 grams/day of betaine for a minimum of 6 weeks can lower plasma homocysteine.” By helping fight hardening and blocking of arteries due to elevated homocysteine, betaine may be beneficial in reducing the risk for heart attacks, stroke, and other forms of cardiac arrest and heart disease. 2. Has Anti-Inflammatory Effects New research indicates that betaine has anti-inflammatory functions, offering protection against numerous diseases — including obesity, diabetes, cancer and Alzheimer’s disease. Its protective effects are in part due to its role in sulfur amino acid metabolism, which defends against oxidative stress, inhibits inflammatory responses, regulates energy metabolism and mitigates apoptosis. 3. May Help Improve Muscle Mass Though research from clinical trials is mixed and somewhat limited in humans, ongoing betaine supplementation has been shown to reduce fat (adipose) mass and increase muscle mass in animal studies and selective human studies. To date, several studies have been done to research whether betaine benefits exist for building strength and muscle mass. Different studies have showed varying results. A 2010 study reported increased muscle power output and muscle force production after betaine supplementation. Another 2009 study found that two weeks of betaine supplementation in active college males appeared to improve muscle endurance during squat exercises and increased the quality of repetitions that could be performed. A 2013 study revealed that six weeks of betaine supplementation improved body composition, arm size and bench press work capacity; attenuated the rise in urinary homocysteine thiolactone; and tended to improve power but not strength. To draw a conclusion, in 2013, a study was done by the Journal of the International Society of Sports Nutrition. Participants were tested to see whether six weeks of betaine supplementation would have impacts on body composition, strength, endurance and fat loss. After six weeks of betaine supplementation, participants showed improved body composition, gains in the size of arm muscles, and higher capacity to do bench press weightlifting and squat exercises. On the other hand, a 2017 systematic review found that among seven studies, only two reported increases in strength or power after supplementation with BET. The remaining five studies showed no change in any strength or power outcome measures with supplementation. 4. May Help with Fat Loss According to certain studies, betaine supplementation may be beneficial in altering how the body processes and partitions nutrients, resulting in quicker fat burning abilities and fat loss, without breaking down muscle tissue or losing muscle mass. A 2018 double-blind, randomized, placebo-controlled trial found evidence that betaine supplementation may enhance reductions in fat mass among female college athletes. The study found that 2.5 grams of supplementary betaine per day with nine weeks exercise training in 11 young women decreased body fat more than a placebo. A separate 2019 systematic review that included six studies with 195 participants concluded that: Betaine supplementation significantly reduced the total body fat mass and body fat percentage. No changes were observed regarding body weight and body mass index. The results suggested that dietary betaine supplementation might be an effective approach for reducing body fat. The review also pointed out that favorable effects of betaine on reducing body fat have been shown in studies using animals, such as rodents, pigs and fowls. 5. Helps with Liver Function and Detoxification Another positive effect of betaine seems to be supporting liver health by assisting in detoxification and the process of the liver digesting fats (lipids). Fat can accumulate to dangerous levels in the liver from certain conditions — such as alcohol abuse, obesity, diabetes and other causes — but betaine is able to assist in liver-cleansing functions of breaking down and removing fats. Betaine also seems to help the liver to dispose of toxins and chemicals, preventing against damage to the digestive tract and other bodily damage that can result from toxin exposure. It has also been found to protect the liver against hepatotoxins, such as ethanol and carbon tetrachloride, which are toxic chemical substances that can enter the body through some medications, drugs and pesticides. 6. Can Aid in Digestion Betaine is sometimes used to create betaine hydrochloride (HCl) supplements. Betaine HCI is thought to increase the concentration of hydrochloric acid in the stomach, which is the acid that must be present in order to break down foods and use nutrients. In certain groups of people who have low stomach acid, they can experience a range of digestive problems that betaine may be able to help relieve. Certain people find it beneficial to take betaine HCl extract prior to meals to help enable the stomach to dissolve and process foods. Positive results have been found in people who suffer from indigestion due to medications or other digestive problems. Taking betaine HCl before meals may be able to help promote a healthy digestive response and gut health. This is also important because the immune system heavily relies on the health of the gut flora to boost immunity. 7. Helps Relieve Aches and Pains Studies have shown that betaine may positively benefit those with muscle aches and pains. In one study conducted on horses, levels of lactate acid (associated with muscular fatigue) were lower after exercise when horses received betaine supplementation. This may be beneficial for people when performing rigorous exercise or for those who suffer from painful symptoms related to muscle and joint tissue damage. 8. Helps Repair Bodily Damage from Alcoholism Betaine is used to treat alcoholic liver damage that results in the accumulation of fat in the liver. It has lipotropic (fat-reducing) effects, so it has been shown to produce significant improvements in treating fatty liver disease by helping the liver process and remove fats. 9. Can Support Skin Health What is betaine in skin care products beneficial for? It’s thought to have certain anti-aging effects, such as helping prevent wrinkles. It can also keep skin moisturized by acting as a natural hydrator due to the way it keeps moisture locked into the skin. This means it helps protect skin’s texture, while potentially soothing irritated and dry skin. Signs of Deficiency A betaine deficiency is not thought to be common in Western nations, mostly because dietary intake is adequate. One reason is because betaine is present in high amounts in wheat products, which are a staple in most people’s diets. What happens when you skip out on betaine-rich foods? Although it’s not directly due to low betaine intake, low dietary intake may contribute to high homocysteine in the blood. High homocysteine levels in the blood may be elevated for many reasons, including environmental factors, diet and genetics. The biggest threat to consuming low betaine levels is experiencing symptoms related to high homocysteine in the blood. This is seen most often in either older populations above 50, those who have suffered from alcoholism or in children who have genetic conditions that lead to high homocysteine. Although this condition is rare, severely elevated levels of homocysteine can cause developmental issues, osteoporosis (thin bones), visual abnormalities, formation of blood clots, and narrowing and hardening of blood vessels. Top Food Sources Which foods contain betaine? Here are 12 of the best food sources of betaine: Wheat Bran — 1/4 cup uncooked (about 15 grams): 200 mg Quinoa — About 1 cup cooked or 1/4 cup uncooked: 178 mg Beets — 1 cup raw: 175 mg Spinach — 1 cup cooked: 160 mg Amaranth Grain — About 1 cup cooked or 1/2 cup uncooked : 130 mg Rye Grain — About 1 cup cooked or 1/2 cup uncooked: 123 mg Kamut Wheat Grain — About 1 cup cooked or 1/2 cup uncooked: 105 mg Bulgar Grain — About 1 cup cooked or 1/2 cup uncooked: 76 mg Sweet Potato — 1 medium potato: 39 mg Turkey Breast — 1 breast cooked: 30 mg Veal — 3 ounces: 29 mg Beef — 3 ounces cooked: 28 mg According to reports, wheat bran/wheat germ is the single highest source of naturally occurring betaine. Therefore, in the average American’s diet, baked products that contain wheat germ — including foods like breads, crackers, cookies and flour tortillas — are thought to be major contributors to betaine intake. These are not necessarily the healthiest sources, but because these types of processed products are unfortunately eaten in high quantities in the U.S. diet, they are usually how people obtain enough this nutrient on a daily basis. Alcoholic beverages, such as wine and beer, also contain low to moderate levels, so their high consumption rates make them another key contributor in the American diet. However, keep in mind that there are definitely healthier alternatives to getting the levels of betaine that you need. Try making some of these recipes below, which include betaine-rich foods like spinach, beets, quinoa and turkey. For breakfast: Baked Eggs with Spinach, Crustless Spinach Quiche or Quinoa Banana Oat Pancakes For lunch: Beet and Goat Cheese Salad For dinner: 47 Turkey Recipes For any time of day: Baked Quinoa with Apples or Beet Juice Dosage and Supplements There’s not an established daily recommended amount of betaine at this time for adults. Recommended doses vary depending on the conditions being treated, and more research is still being conducted to establish a set recommendation for the general public. Betaine is generally considered safe at a daily intake of nine to 15 grams for adults. For people with alcohol-induced fatty liver disease, the recommended amount of betaine supplementation is normally between 1,000 to 2,000 milligrams, taken three times daily. This is a high dose and more than normally would be taken, but it is needed to repair liver damage in certain cases, like with recovering alcoholics. Lower doses are usually used for nutritional support in people who have healthy livers and no history of heart disease. To help with digestion, there are many supplements (in the form of betaine HCl) available on the market that range in recommended doses between 650–2,500 milligrams. People who are looking for help with exercise performance, improving body composition, or relieving body...

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Threonine: The Amino Acid Needed for Collagen Production

AHA Publisher — Fri, 25 Oct 2019 07:00:30 +0000

Christine Ruggeri, CHHC via Dr. Axe – Threonine is an essential amino acid that plays an important role in regulating protein balance in the body. Because it’s considered an “essential amino acid,” that means the body doesn’t synthesize the amino acid, so we need to eat foods high in threonine to obtain it. Chances are you haven’t heard much about threonine, but this amino acid is involved in a range of biological processes. It’s best known for its role in forming the foundation of connective tissues like collagen and elastin. It also helps regulate digestion, mood and muscle growth. Essential amino acids like threonine are the building blocks of proteins. They play a vital role in the structure of our bones, muscles and skin. When we don’t eat enough foods high in these important compounds, we can experience deficiency symptoms like mood changes, irritability, confusion and digestive problems. This is just another reason why it’s so important to eat a well-balanced diet that included a range of high-protein foods, ensuring that you get enough essential amino acids. What Is Threonine? Threonine is an essential amino acid that plays an important role in regulating protein balance in the body. Because it’s considered an “essential amino acid,” that means the body doesn’t synthesize the amino acid, so we need to eat foods high in threonine to obtain it. The threonine abbreviation is Thr, and its one letter code is T. The proper threonine pronunciation is “three-uh-need.” The threonine formula is C4H9NO3, and it contains an a-amino group, a carboxyl group and a side chain containing a hydroxyl group. This makes the threonine structure a polar, uncharged amino acid. Thr amino acid occurs naturally in the L-form, L-threonine. It’s a conjugate base of L-threoninium and a conjugate acid of L-threoninate. Here are some common questions about the structure of threonine amino acid: • How many stereoisomers does threonine have? Thr has four possible stereoisomers: (2S,3R), (2R,3S), (2S,3S) and (2R, 3R). • Is threonine positively charged? T amino acid is considered to have polar properties. • Is threonine acidic or basic? Thr is considered polar, while amino acids lysine and arginine are considered basic and charged, and aspartate and glutamate are acidic and negatively charged. • What is the threonine codon code? The possible threonine codons include ACA, ACC, ACG and ACT. Amino acid T is a precursor to serine and glycine, two other amino acids that are needed for the body to function properly. Glycine is a conditionally essential amino acid, which means that it’s made in small amounts by the human body. It’s also available in foods, and many people can benefit from consuming more from their diets. This is especially true if the person has a medical condition that limits the synthesis of glycine. Threonine Benefits 1. Supports Digestive Health Threonine protects the digestive tract by producing a mucus gel layer that covers it and serves as a barrier to damaging digestive enzymes. This important amino acid also supports healthy gut function by promoting the protective effects of the gut mucus barrier. According to research published in Frontiers in Bioscience, a large proportion of dietary threonine is utilized for intestinal-mucosal protein synthesis. For this reason, consuming Thr foods may help to improve gut health under physiological and pathological conditions in both humans and animals. 2. Boosts Immune System We need enough Thr to support proper immune function. The thymus gland uses the essential amino acid to make T-cells, or T lymphocytes, that work to fight off infections inside the body. Research published in Cold Spring Harbor Perspectives in Biology states that “serine/threonine kinases control the epigenetic, transcriptional and metabolic programs that determine T-cell function.” Researchers explain that at a basic level, serine and threonine kinases work as a series of on/off switches that trigger antigen and cytokine receptors that make up the immune system. 3. May Improve Muscle Contractions Although more research is needed to further understand its role, there is some evidence that Thr may benefit symptoms of ALS, aka Lou Gehrig’s disease. Thr amino acid works to increase glycine levels in the central nervous system. Glycine is used to treat spasticity, which is why L-threonine has been assessed for its ability to improve spasticity, or contracting muscles, in ALS patients. In a review conducted in Australia, researchers found that a double-blind, placebo-controlled study of oral L-threonine to treat spinal spasticity indicates a modest antispasmodic effect. However, studies involving ALS patients show no improvements with L-thr treatment. These mixed reviews suggest that using L-threonine supplements may help reduce muscle contractions but may not be effective for ALS symptoms. 4. Supports Muscle and Bone Strength Did you know that collagen and elastin proteins need threonine for proper production? You may already know that collagen is the most abundant protein in the body, and it’s found in our muscles, bones, skin, blood vessels, tendons and digestive system. Because Thr allows for the production of collagen, it plays a vital role in the health of your bones and muscles. Research conducted Texas A&M University indicates that glycine from threonine, proline and hydroxyproline contributes to 57 percent of total amino acids in collagen. Thr amino acid is a precursor to glycine, which is also used during the biosynthesis of creatine, providing muscles with a direct source of fuel to repair damage. Threonine also allows for proper elastin function. Elastin is a protein that’s found in connective tissue and lets the skin, tendons and ligaments resume shape after stretching or contracting. 5. Helps Prevent Fatty Liver Thr amino acid prevents fat buildup in the liver. It does this by regulating fat metabolism and facilitating lipotropic function. Liptropic compounds work to break down fat during metabolism, and without the amino acids threonine, methionine and aspartic acid, this wouldn’t be possible. Threonine deficiency can lead to fatty liver and even liver failure. An animal study published in the American Journal of Physiology found that Thr-deficient diets increase mitochondrial uncoupling in the liver. This means that diets lacking quality protein foods that provide essential amino acids can lead to cell malfunction and the buildup of fats in the liver. 6. May Alleviate Anxiety and Mild Depression Studies shows that alternations in serum levels of amino acids, including serine and glycine, which require Thr for production, are linked to major depression. Researchers in Belgium found that changes in levels of threonine, aspartate, asparagine and serine may predict a patient’s response to treatment with antidepressants by modulating amino acid levels in the body. Because Thr is a precursor to glycine, which helps calm nerves and support cognitive health, it’s often used as a supplement to relieve signs of anxiety and depression. Glycine is also known for its ability to help improve sleep, mental performance, mood and memory. Related Articles: Essential Amino Acids Benefits for Weight Loss, Muscle Gain and Even Mood Best Collagen-Rich Foods and Collagen-Boosting Foods 7. Accelerates Wound Healing Threonine is needed for the proper production of collagen, which is required for connective tissue formation and wound healing. Research shows that after experiencing burns or trauma, individuals have greater urinary spill of threonine. This indicates that the amino acid is metabolized from body tissues after an injury. Increasing your intake of Thr through amino acid T foods or supplements may help speed healing of wounds, burns and other forms of trauma. Threonine Deficiency Symptoms and Causes Threonine deficiency is rare, as most people get enough of the amino acid in the foods they eat. However, people with an unbalanced diet, vegans and vegetarians, may not consume enough threonine foods, which can cause low levels of the amino acid. Thr deficiency may cause the following symptoms: • digestive problems • irritability or emotional agitation • confusion • increased liver fat • poor nutrient absorption Threonine Foods and Supplements What is threonine found in? Amino acid T is found in nature in L-threonine form. A well-balanced diet that includes high-quality protein foods will provide the body with enough to maintain normal levels. The top threonine foods include: 1. Organic meat (including chicken, lamb, beef and turkey) 2. Wild-caught fish (including wild salmon) 3. Dairy products 4. Cottage cheese 5. Eggs 6. Carrots 7. Bananas 8. Sesame seeds 9. Pumpkin seeds 10. Kidney beans 11. Edamame 12. Spirulina 13. Lentils Thr deficiency is rare for people who eat a well-balanced, high-protein diet. For vegans and vegetarians, eating beans, seeds and peas will help maintain normal levels. L-threonine powder and capsules are available online or in most health food stores. You may also find that elastin supplements contain L-threonine. How to Take Threonine and Dosage You’ll likely find threonine supplements as 500-milligram capsules that can be taken up to three times daily, depending on your health needs and level of T amino acid deficiency. The most common L-threonine dose is 500–1,000 milligrams daily. Research suggests that doses up to four grams per day for 12 months are likely safe. If you use L-threonine to reverse a deficiency or improve symptoms of any health condition, do it under the care of a doctor or health care professional. Threonine Recipes There are so many ways to incorporate Thr into your diet. Focus on getting enough protein in your meals. You can do this with organic meats, wild-caught fish, eggs, beans, nuts and seeds. Here are some healthy and delicious recipes to get you started: • Pecorino Mushroom Chicken Recipe: This is a low-carb, gluten-free and keto-friendly chicken recipe that also includes mushrooms, ghee, cloves and pecorino cheese. • Heart-Healthy Eggs Benedict Recipe: This healthy version of eggs Benedict is made with anti-inflammatory foods like avocado, asparagus and tomato. • Turkey Chili with Adzuki Beans Recipe: This combination of turkey and beans is high in this amino acid. In addition to protein, this recipe is also high in healthy fats and iron. Precautions/Side Effects Although supplementing with threonine in appropriate amounts is generally considered safe, some people may experience minor side effects, such as headache, nausea, upset stomach and skin rash. There is not enough evidence to recommend that women who are pregnant or breastfeeding should take threonine supplements. Instead, it’s best to get enough of the amino acid from a well-balanced diet. People taking NMDA antagonists called memantine (Namenda), which are a type of medication for Alzheimer’s disease, should avoid using this supplement. The amino acid may reduce how well these medications work. Final Thoughts • What is the function of threonine? The threonine definition is an essential amino acid that plays an important role in regulating protein balance in the body. • Benefits of this amino acid include its ability to support digestive health, boost the immune system, improve muscle strength, reduce muscle spasms, relieve anxiety and mild depression, and speed wound healing. • What foods are high in threonine? High-quality protein foods, including organic meats, wild-caught fish, eggs, organic dairy products, seeds and beans are high in the Thr amino acid. • For those who aren’t getting enough Thr in their diets, supplementing with it may help to maintain normal levels. Capsules and powders are available online and in health food stores. To read the original article click here. For more articles by Dr. Axe.

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