altered brain function Archives - Amazing Health Advances

Do I Need an Epileptologist?

The AHA! Team — Mon, 18 Aug 2025 05:37:03 +0000

Morgan deBlecourt via Duke Health – An epileptologist is a neurologist who specializes in caring for people with epilepsy. Epileptologists have completed an additional one to two years of subspecialty training in epilepsy care. Most people with epilepsy can see a primary care doctor or general neurologist to manage their seizures. However, you may need more advanced care if your seizures are not under control, if you have certain medical issues, or if you want a second opinion. An epileptologist is a neurologist who specializes in caring for people with epilepsy. Epileptologists have completed an additional one to two years of subspecialty training in epilepsy care. When to See an Epileptologist To confirm your epilepsy diagnosis If your seizures are not under control after three months of care by your primary care physician or after one year of care by a general neurologist If your seizures are not under control despite trying two or three different medications If you are experiencing unwanted side effects from medications If you have other medical conditions or considerations that affect or are affected by epilepsy If you are pregnant or want to become pregnant Seek Care at an Epilepsy Center “An epileptologist typically works in a designated epilepsy center, which is capable of evaluating people whose seizures are not under adequate control. An epilepsy center provides a very comprehensive approach to care,” said Duke epileptologist Aatif Husain, MD. An epilepsy center is staffed by specialists who use sophisticated testing to pinpoint your diagnosis, offer the latest treatments, address possible side effects of medications, recommend surgical options if appropriate, and help you manage the social and emotional aspects of epilepsy. “Advances over the past decade have enabled more personalized epilepsy care,” said Duke epileptologist Birgit Frauscher, MD. “With new options now available, regular re-evaluation of treatment is essential.” As a Level 4 Epilepsy Center, Duke is recognized by the National Association of Epilepsy Centers for providing the highest level of diagnostic, treatment, and surgical options. To read the original article click here.

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When Your Loved One has Aphasia

The AHA! Team — Mon, 28 Jul 2025 05:28:22 +0000

Meredith Nye, CCC-SLP, MS, via Duke Health – Speech pathologists can help relatives and friends work with a loved one who has aphasia and find ways to communicate effectively. Aphasia is a language disorder that can affect comprehension and communication. Although it is most often caused by a stroke, aphasia can also result from traumatic brain injury, brain tumors, or progressive neurological disorders such as primary progressive aphasia (PPA). These conditions damage the language centers of the brain, leading to difficulties with speaking, understanding, reading, and/or writing. Learning to communicate with someone who has aphasia can positively impact that person’s social interactions, relationships, medical decision-making, and overall wellbeing. “We work with patients and their care partners to provide customized treatment plans focusing on life participation and maximizing communication success,” says Meredith Nye, CCC-SLP, MS, a Duke speech-language pathologist. “Aphasia doesn’t impact a person’s hearing or thinking skills like memory. Rather,” she says, “people with aphasia may use the wrong word, like ‘mother’ instead of ‘daughter’ or ‘yes’ instead of ‘no.’ Or they may make up words, unintentionally repeat themselves, or only be able to say a few words or sounds when they are trying to communicate. Or they may have a hard time understanding what you’re saying.” How to Communicate with Someone with Aphasia Speech pathologists can help relatives and friends work with a loved one who has aphasia and find ways to communicate effectively. Nye recommends keeping these tips in mind: Focus Their Attention If possible, move your conversation to a quiet, well-lit room where there are no distractions. Turn off background disturbances like the radio or television. It’s best to limit conversation to one or two people at the most. Use All Forms of Nonverbal Communication Rather than rely on words, use a wave to say “goodbye” or “hello.” Thumbs up can be used to say “good job” or “yes.” Your facial expressions can show anger, sadness, or elation. Exchange written or drawn messages. Have Patience Sometimes it takes longer for a person with aphasia to communicate. Count to 10 slowly before providing help or choices. Many times it takes that much time or longer for them to get their message out. Confirm Your Understanding After an exchange with your loved one, make sure you understand by verbally repeating or by writing a synopsis of the message’s key points. If they wanted coffee, write “coffee” and draw a picture. Use intonation in your voice when you ask, “You want coffee?” and point to the picture. Have them answer yes or no. Use Technology Computers, smart devices, and other forms of technology can help people with aphasia return to hobbies, read, and converse with others. Icons and emojis can enhance email and social media conversations. Encourage your loved one to listen to audiobooks in addition to reading the print versions. Speech pathologists can also recommend programs that enable your loved one to use word-prediction or speech-to-text capabilities. Get Help Speech pathologists can help people make progress even years after they are originally diagnosed with aphasia, says Nye. “We can help them focus on their strengths and find ways to better engage with family and their community. We can offer tools to help them socialize and have a better quality of life through communication.” Find Aphasia Support Groups There are many groups and resources in the community to support people with aphasia and their families. Nye says a speech-language pathologist is your best resource for identifying groups in your area. To read the original article click here.

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Are Gender and Sexual Identity Linked to Brain Health?

The AHA! Team — Wed, 06 Nov 2024 06:51:50 +0000

American Academy of Neurology (AAN) via Newswise – LGBTQ+ people may be more likely to have negative brain health outcomes, including a higher risk of dementia and late-life depression, than people who are straight, according to a recent study published in the online issue of Neurology®, the medical journal of the American Academy of Neurology. LGBTQ+ people may be more likely to have negative brain health outcomes, including a higher risk of dementia and late-life depression MINNEAPOLIS – LGBTQ+ people may be more likely to have negative brain health outcomes, including a higher risk of dementia and late-life depression, than people who are cisgender and straight, according to a study published in the September 25, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. These results do not prove that sexual or gender diversity causes neurological diseases, they only show an association. LGBTQ+ refers to people who are lesbian, gay, bisexual, transgender, and nonbinary, plus other people who are sexually or gender diverse. Sexual diversity refers to individuals whose sexual orientation is different from straight, including lesbian, gay or bisexual people. Gender diversity refers to individuals whose gender identity does not align with the sex they were assigned at birth, which includes transgender and nonbinary people. Cisgender refers to individuals whose gender identity matches their sex assigned at birth. “In a world that increasingly recognizes the crucial role of equitable health care, it remains concerning how little is known about the health disparities faced by LGBTQ+ people,” said study author Shufan Huo, MD, PhD at the Yale School of Medicine in New Haven, Connecticut. “Our study looked at this group, which has been historically underrepresented in neurological research, and found that they had an increased risk of adverse brain health outcomes.” For the study, researchers evaluated data from 393,041 people with an average age of 51. Of the total group, 353,409 were cisgender and straight people, and 39,632 were LGBTQ+ people. Researchers evaluated electronic health records and self-reported data to identify a composite score of the following neurological conditions: dementia, late-life depression and stroke. They then evaluated each disease separately and looked at all subgroups of the LGBTQ+ participants. A total of 21,091 people had a neurological disease. Of those, 11,553 people had late-life depression, 6,605 people had strokes and 2,933 people had dementia. After adjusting for factors that could affect the risk of these three neurological conditions, such as age, smoking or high blood pressure, researchers found that LGBTQ+ people were 15% more likely to develop negative brain health outcomes in these conditions when compared to people who identified as cisgender and straight. Researchers also found that LGBTQ+ people had a higher risk of dementia and late-life depression, 14% and 27% respectively, than people who were cisgender and straight. “Our findings underscore the need for further research focusing on the health care disparities affecting the LGBTQ+ community,” Huo said. “Possible reasons for these disparities could include discrimination, stress, access to health care and policy and legal factors.” When looking at stroke, researchers found a higher risk only for transgender women, who were 68% more likely to have a stroke than cisgender people. A limitation of the study was that it did not look at the causes and mechanisms behind the inequities faced by LGBTQ+ people. For example, the study did not look at gender-affirming hormone therapy in transgender people, which could play a role in increased stroke risks in transgender women. The study was supported by the German Research Foundation. To read the original article click here.

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Malfunctioning Blood-Brain Barrier Is Linked to Benign Forgetfulness of Aging

AHA Publisher — Wed, 24 Mar 2021 07:00:06 +0000

University of Washington School of Medicine/UW Medicine via News-Medical – Have you forgotten where you laid your keys? Ever wondered where you had parked your car? Or having trouble remembering the name of the new neighbor? Unfortunately, these things seem to get worse as one gets older. A big question for researchers is where does benign forgetfulness end and true disease begin? One of the keys to having a healthy brain at any age is having a healthy blood-brain barrier, a complex interface of blood vessels that run through the brain. Researchers reviewed more than 150 articles to look at what happens to the blood-brain barrier as we age. Their findings were published March 15 in Nature Aging. Whether the changes to the blood-brain barrier alters brain function, however, is still up for debate. “It turns out very little is known how the blood-brain barrier ages. It’s often hard to tell normal aging from early disease.” (William Banks, Study Lead Author and Gerontology Researcher, School of Medicine, University of Washington) Banks is a researcher with the Geriatrics Research Education and Clinical Center at the Veterans Affairs Puget Sound Health Care System The blood-brain barrier, discovered in the late 1800s, prevents the unregulated leakage of substances from blood into the brain. The brain is an especially sensitive organ and cannot tolerate direct exposure to many of the substances in the blood. Increasingly, scientists have realized that the blood-brain barrier also allows many substances into the brain in a regulated way to serve the nutritional needs of the brain. It also transports informational molecules from the blood to the brain and pumps toxins out of the brain. A malfunctioning blood-brain barrier can contribute to diseases such as multiple sclerosis, diabetes, and even Alzheimer’s disease. Before scientists can understand how such malfunctioning can contribute to the diseases of aging, they need to understand how a healthy blood-brain barrier normally ages. Research shows that healthy aging individuals have a very small leak in their blood-brain barrier. This leakage is associated with some measures of the benign forgetfulness of aging, considered by most scientists to be normal. But could this leak and the difficulties in recall be the early stages of Alzheimer’s disease? When a person carries the ApoE4 allele, the strongest genetic risk of Alzheimer’s risk, researchers said there is an acceleration of most of the blood-brain barrier age-related changes. People with ApoE4 have a hard time getting rid of amyloid beta peptide in their brains, which causes an accumulation of plaque. With healthy aging, the pumps in the blood-brain barrier work less efficiently in getting rid of the amyloid beta peptide. The pumps work even less well in people with Alzheimer’s disease. Another key finding in the review is that as we age, two cells begin to change in the blood-brain barrier: pericytes and astrocytes. Recent work suggests that the leak in the blood-brain barrier that occurs with Alzheimer’s may be due to an age-related loss of pericytes. Astrocytes, by contrast, seem to be overactive. Recent work suggests that preserving pericyte function by giving the factors that they secrete or even transplanting them could lead to a healthier blood-brain barrier. Some research suggests that pericyte health can be preserved by some of the same interventions that extend lifespan, such as regular exercise, caloric restriction, and rapamycin. Other findings raise the question of whether the brain’s source of nutrition and its grip on control of the immune and endocrine systems could deteriorate with aging. Another finding raises the possibility that the rate at which many drugs are taken up by the brain may explain why older folks sometimes have different sensitivities to drugs than their children or grandchildren. To read the original article click here.

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